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Ceftazidime: Uses, Dosage, and Effects

Ceftazidime is a third-generation cephalosporin antibiotic used to treat central nervous system infections. It works by inhibiting the synthesis of the bacterial cell wall, causing cell death. It can cause adverse effects like headache, nausea, vomiting, and nephrotoxicity. Precautions include assessing for liver and renal dysfunction, obtaining cultures before and during therapy, administering separately from aminoglycosides, and discontinuing use if hypersensitivity occurs.

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2K views2 pages

Ceftazidime: Uses, Dosage, and Effects

Ceftazidime is a third-generation cephalosporin antibiotic used to treat central nervous system infections. It works by inhibiting the synthesis of the bacterial cell wall, causing cell death. It can cause adverse effects like headache, nausea, vomiting, and nephrotoxicity. Precautions include assessing for liver and renal dysfunction, obtaining cultures before and during therapy, administering separately from aminoglycosides, and discontinuing use if hypersensitivity occurs.

Uploaded by

RadicalRay
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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NURSING

DRUG ORDER MECAHNIS INDICATION CONTRAINDICATIO ADVERSE EFFECTS INTERVENTION and


M OF S NS OF THE DRUG PRECAUTIONS
ACTION
Generic name: ♥ Inhibits ☻ CNS ☼ Contraindicated to CNS: Headache, ☻ Assess for liver and
• ceftazidime synthesis of infections patients with dizziness, renal dysfunction
bacterial cell allergies to thethargies, ☻ Culture infection,
Brand name: wall, causing penicillins, paresthesias and arrange sensitivity
• Tazidime cell death. cepahlosporins. tests before and during
GI: nausea, vomiting, therapy if expected
Classification: anorexia, response is not seen.
• Antibiotic abdominal pain, Warning:
• Cephalospor flatulence,
in (third psuedomembrano ☻ Do not mix with
generation) us colitis, liver aminoglycoside
toxicity solutions, administer
Dosage: these drugs
GU: Nephrotoxicity separately.
• 300 mg
☻ Powder and
Hematologic: bone reconstituted solution
Route: marrow depression- darken with storage.
• IVTT decreased WBC, ☻ Have Vit. K available
decreased platelets, in case
Frequency: decrease Hct hypoprothrombinemia
• q 8 hr occurs
• ANST(-) Hypersensitivity: ☻ Discontinue if
ranging from rash to hypersensitivity occurs
fever to anaphylaxis, ☻ Teach SO that
serum sickness patients may
reaction experience upset
stomach or diarrhea
Local: Pain, abscess but must report
at injection site, severe diarrhea,
phlebitis, difficulty breathing,
inflammation at IV fatigue, pain at
site injection site.

Other:
Superinfections,
disulfiram-like
reactions with alcohol

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