on.
i
t
c
i
r
t
act:
t
s
n
e
r
o
right please c
y
p
o
C
ghts is.com
i
r
e
R F)
(
g
b
a
r
2
s
o
2
.c
1
For u
www er R F244
umb
n
e
imag
cobas 4000 analyzer series
The two belong together
cobas brand
Roche Diagnostics introduces the cobas brand as the umbrella
for products used to complete or expand the screening, diagnostic
and monitoring applications of the professional laboratory.
cobas brand includes:
serum work area with clinical chemisty
and immunochemistry
data management and preanalytical solutions
products for coagulation analysis and urinalysis
instruments for rapid blood and
cardiovascular testing
PCR-based applications for virology
and womens health testing
cobas modular platform
Flexibility you can build on
Todays laboratories are challenged with delivering high standards of laboratory services with fewer resources. They face
constant pressure to lower operating costs while aspiring to
grow their business in new areas. Their concern for patient care
is paramount, and they demand only the best in diagnostic
testing and services.
Just as every patient requires individualized care, every laboratory is unique. Striking the balance between high standards
and efficient operation requires tailor-made solutions. With
cobas modular platform, Roche has developed a platform
concept that delivers individualized solutions based on a common architecture for various workloads and testing requirements.
Common universal reagent carriers
Simplifies logistics
Efficient use of reagents
Common applications
and analytical technologies
Comparable patient results
Combines routine and innovative testing
Common operator interface
cobas 4000 is the second member of the new cobas modular
platform. It offers small workload laboratories a complete
solution for clinical chemistry and immunochemistry testing.
Requires less training
Promotes staff flexibility
The cobas modular platform is designed to reduce the complexity of laboratory operation and provides efficient and
compatible solutions for network cooperation.
1 Operator in
terface
Analytica
150
l modules
Different
ailable
assays av
cobas 4000 analyzer series
The two belong together
N EW 7
0
in 20
Complete serum work area testing
cobas 4000 performs clinical chemistry and immunoassay
testing for laboratories processing 80-200 serum samples/day.
Its menu of over 150 routine and innovative assays satisfies
virtually all of the testing needs for small workload laboratories.
Compact yet powerful
cobas 4000 includes the cobas c 311 analyzer for clinical
chemistry and cobas e 411 analyzer for immunoassays.
The combination of the two analyzers provides true
operational integration for small workload laboratories.
A capacity of up to 63 combined onboard tests enables full
indication panels for diagnosis and therapy monitoring.
Convenience in operation
cobas reagent packs are always ready to use and highly
stable for efficient usage.
Confidence in results
Common cobas user interfaces enable users seamless
and flexible operation between analyzers.
Online updates and remote service access via
cobas e-services expedite service and support.
Roche/Hitachi in design and manufacture, cobas 4000
continues the long tradition of proven reliability.
Electrochemiluminescence (ECL) technology sets
high standards of analytical performance and time to result.
One grip handling of reagents
The unique concept of the cobas c packs and cobas e packs
allows for convenient reagent handling.
All reagents are ready to use and are closed for protection
from external elements.
Reagent stability of up to 3 months once opened guarantees
efficient usage even for esoteric assays.
Over 90% of all reagents require calibration only once per lot.
Over 70% of all reagents require a sample volume of less
than 50 microliters.
cobas c pack multi enables development channels for userdefined reagent applications.
Loading cobas c pack onto the cobas c 311 analyzer
Pippetting reagent from cobas e pack on the cobas e 411 analyzer
cobas 4000 analyzer series
The two belong together
N EW 7
0
in 20
cobas c 311 analyzer
Clinical chemistry
ISE: potassium, sodium, chloride
Homogeneous immunoassays
HbA1c whole blood measurement
Integrated with cobas e-services
Throughput up to 480 tests/hour
45 direct access assays
Color touchscreen with mouse
Contact-free ultrasonic mixing
Clot detection
cobas e 411 analyzer
Heterogeneous immunoassays
Nine minute STAT applications
Cardiac markers including proBNP
Over 50 assays for anemia, bone, cancer,
hormones and infectious diseases
cobas e-services optional
Throughput of up to 88 tests/hour
18 direct access assays
Carry-over free disposable tips
Clot detection
Three ways to unmatched performance
As the heart of the cobas e 411 analyzer, ECL technology
delivers the unique combination of nine minute STAT applications, high analytical sensitivity and wide measuring ranges
for unparalleled performance in immunochemistry.
Wide measuring ranges
High analytical sensitivity
reduces the amount of tests
rerun due to out of range results
enables the use of innovative tests and
requires less sample volume
examples:
Estradiol range of 5 - 4,300 pg/mL
Progesterone range of 0 - 60 ng/mL
total-PSA range of 0 - 100 ng/mL
examples:
Troponin T 4th gen. with <10% CV
at 95th population percentile
hCG+ and TSH requires 10 and 50 L
sample volume, respectively
Nine minutes STAT applications
deliver unmatched turnaround time for
emergency samples
hCG+, Troponin T 4th Gen., CK-MB,
Myoglobin, PTH*
Make STATs part of your routine
With cobas 4000's nine minute STAT applications, you can
seamless integrate STAT samples into your routine workload.
These applications include:
- hCG+
- Troponin T 4th Gen.
- CK-MB
- Myoglobin
- PTH*
Faster turnaround-time for these critical parameters will
increase your laboratory's responsiveness to important areas
of the hospital such as the Emergency Department and
Surgery.
tion. act:
c
i
r
t
t res se cont
h
g
i
r
a
Copy ights ple om
r
R F)
.c
(
s
e
i
g
7
b
a
r
0
s
.co
551
For u
www 42-169
ber
m
u
en
imag
* PTH nine minute application in development for March 2007
cobas 4000 analyzer series
Preliminary Specifications
System
cobas 4000 analyzer series includes two stand-alone analyzers for serum work area
testing in small workload laboratories:
cobas c 311 is a fully automated, random access system for clinical chemistry and
homogeneous immunoassay analysis.
cobas e 411 is a fully automated, random access system for heterogeneous
immunoassay analysis. It is available as both a disk system and a rack system.
Test throughput
Up to 300 tests/hr. photometric and ISE on cobas c 311
Up to 88 tests/hr. on cobas e 411
Type of analyzers
cobas c 311: photometric measuring unit including ISE
cobas e 411: ECL technology measuring unit
Number of channels
Up to 63 channels (reagent slots) in total:
Up to 45 channels on cobas c 311
Up to 18 channels on cobas e 411
Available parameters
196 parameters in total:
117 photometric tests, 3 ISE tests, 8 formulas, 3 serum indices on cobas c 311
65 heterogeneous tests with cobas e 411
Sample types
Serum, Plasma, Urine, CSF, Whole Blood (HbA1c only)
Sample container types
Primary tubes
5-10mL; 16x100, 16x75, 13x100, 13x75mm
Sample cup
2.5mL
Micro cup
cobas c 311 only: 1.5mL
Cups on tube
Cup on top of a 16x75/100mm tube
cobas c 311 only: cup on top of one non-standard tube and
false buttom tube
Result integrity
Clot detection available on both analyzers
Disposable tips on cobas e 411
3 test-specific serum indices on cobas c 311; automatic interference flagging of
results provided by cobas IT 3000 work area manager
Rerun/reflex function
Automatic and manual rerun on cobas c 311, manual rerun only on cobas e 411
Automatic reflex is supported by both systems, reflex request to be provided by
cobas IT 3000 work area manager or LIS
Regulatory requirements
CE, UL, C-UL, CB-report and certificate
04952502001 - 1106 - X. Xx
COBAS, COBAS C, COBAS E
and LIFE NEEDS ANSWERS
are trademarks of Roche.
2006 Roche Diagnostics
Roche Diagnostics GmbH
D-68298 Mannheim
Germany
www.roche-diagnostics.com
