TCM Wisdom TubeTM

Treating Infertility in Advance Aged

Women Using the 8 Extra Meridians

by
Brandon Horn
PhD, JD, LAc, FABORM

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Sources of Information
Treating Infertility in Advance
Aged Women Using the
8 Extra Meridians
Brandon Horn

PhD, JD, LAc, FABORM

Main Teachers

Jeffrey C Yuen
Chang Qing
Fred Wu
Paul Yan

Research/PhD Dissertation at the American

University of Complementary Medicine
(AUCM.org)

Tel: (626) 780-7182 Fax: (626) 609-2929

Web: www.elotus.org Email: [email protected]

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine

What is Aging?

Aging Ovaries Illustrated (actual

picture of human ovaries)

Aging is the unfolding of Jing

Jing unfolds through movement (Yang)
Aging is Yang consuming Yin
Yang elements can be:
Physiological (e.g. Yang Qi) or
Pathological (e.g., fire toxins)

The primary (not only) 8EVs involved in the

process of aging are the Wei Channels

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

Characteristics of Aging Ovaries

(slide taken from ovarian reserve seminar)

Lusterless and wrinkled
Decreased in volume
Increasing fibrosis with accumulation of scar
and connective tissue
Reduced vascular network, sclerosis of vessel
walls
Increased apoptotic and necrotic cells

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

The Aging Ovary

Older ovaries show evidence of greater
oxidative damage than those in younger
women
Follicular depletion accelerates during the last
decade of reproductive life

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Tel: 626-780-7182 Fax: 626-609-2929 Website: www.eLotus.org Email: [email protected]
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine.

MorphologyofAgingvs.YoungOvaries
Biol Reprod. 2004 Feb;70(2):419-24. Epub 2003 Oct 15

Mitochondrial Dysfunction (could be physiological or pathological)

Decreased number of mitochondria
Increased mitochondrial density
Increased incidence of mitochondrial membrane rupture in granulosa cells

Smooth endoplasmic reticulum (SER) dysfunction

Increased frequency of dilated SER in granulosa cells (oxidative damage)
SER synthesizes lipids, metabolizes CHO, detoxifies drugs, attaches
receptors to cell membrane proteins

Golgi complex dysfunction

Increase in dilation of golgi complex (oxidative damage)
Golgi processes proteins for secretion by the cell

Increase in vacuole fraction

Vacuole functions include containing waste

Overall follicle quality scores were NOT associated with agerelated ovarian decline

Other Abnormalities Associated with Aging

Ovaries
Increased meiotic non-disjunction in oocyte
Age-related damage due to oxidative stress
Reduced microcirculation around follicles
Hypooxygenation of preovulatory follicle

Deletions in mtDNA
Acupuncture, herbs and nutrition can reduce
oxidative damage, increase microcirculation to
the ovaries, protect mtDNA and improve
follicular oxygenation.
(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

General Causes of Oocyte Aging:

Deficiency and Excess

8EV and Ovarian Aging

Deficiency

8EV can

Weakness or Deficiency of DNA or cellular

structures (8EV)
Deficiency of Protective factors

Excess

Strengthen the Jing (including DNA and cellular

structures)
Release deeply held PFs (including environmental
toxins, microorganisms, etc.)

Excess of insulting factors (e.g., oxidative stress)

(8EV+)
Insulting factors can be:
Endogenous (e.g., byproducts of energy production, etc.)
Exogenous (e.g., environmental toxins, microbes, etc.)

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

(c) 2007 Slide reproduced with permission from Seminar Optimizing Ovarian Reserve
Lotuscenter.com/publications

What are/are not the 8EV

8EV Meridians are conceptual

inventions

8EV are the vessels or conduits of Jing

Chapter 27 of the Nan Jing:

Jing is the fundamental material component of life

Qi Jing Ba Mai:
Why are they strange?

8EV are beyond the reach of the primary channels.

Note: all of the 8EV share common points and/or trajectories
with the PM

Are the 8EV present in an embryo?

Embryogenesis is the unfolding of Jing
Conduits of Jing must be present in an embryo
Where is Chong mai, etc. in an embryo?

Strange Channels
Strange because they have trajectories or aspects
(like other meridians), but no defined path (unlike other
meridians)

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Tel: 626-780-7182 Fax: 626-609-2929 Website: www.eLotus.org Email: [email protected]
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine.

Slowing Aging: an 8EV Perspective

8EV Meridians are only one

strategy for accessing the true 8EV

Energetics of structural integrity comes

primarily from the Wei vessels
Wei vessels:
Maintain structural integrity (morphology)
Assist in the removal of PFs located at the Jing
level
Help remove scar tissue and other morphological
factors stagnating the Jing
Increase the longevity of cells

Yinwei Mai

Yinwei Treatment Protocol for Ovarian Aging

Governs susceptibility to aging

Consolidate and strengthens oocytes

Strengthens integrity of Jing to protects from both

exogenous and endogenous insults
Governs time and the keepers of time (e.g.,
telomeres)
Prolongs life of ovaries.

Pair with Dai Mai (Tonification) for added effect on

protecting DNA
Sample Point Prescription: Sp13(+), Kd9(+), Pc6, Pc7, GB1,
KD7(+), Sp10(-), Sp6(+)
Note: Dont need to use all of these points

Caution: Overtreatment may increase risk of

non-disjunction
If pulses begin to deviate medially or new signs of
stagnation develop you may have over-treated.
If so, treat Yangwei mai and pulses should balance.

Yangwei Linking Mai

Yangwei treatment protocol for Ovarian Aging

Important for proper DNA replication

Sample point prescription for optimal

disjunction: UB63(-), GB35(-), GB29(-),
GB15(-), TH4, TH5(-), Sp 6(+)
Caution: Overtreatment can deplete yin and
destabilize Jing

Controls disjunction
Helps prevent aneuploidy (e.g., Down Syndrome)

Assists with removal of toxins and other PFs from the

Jing level

Always assess the state of yin and blood during

treatments. If deficiency begins to arise, stop
treatment until yin stabilizes then continue.

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Tel: 626-780-7182 Fax: 626-609-2929 Website: www.eLotus.org Email: [email protected]
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine.

Diagnostic suggestions for using Wei Mai

Case Study

Pulses Simplified:

Female

Normal pulses should have a straight trajectory

Deviations are assessed from proximal to distal
Inward deviations: yinwei excess/ yangwei deficiency
Outward deviations: yangwei excess/yinwei deficiency
Both Inward and Outward: treat both channels and treat the
liver PM
Neither Inward or Outward (i.e., no deviations): treat yinwei
(+)

Case Study
Pulses: rapid, flooding and deviated medially in
the Lr position. Lu x diff, sl. Rapid. Kd choppy
and rapid, Pc sl. Flooding and tight
Tongue: Red tip, swollen on the right side,
yellow coating in the back with red papules
visible.
Inspection: nails had several dark vertical
stripes. Luo vessels apparent at Sp 21 and
Lr14.

42 y/o
G3P0A3
5 rounds of IVF: 2 chem +, 1 fhb aborted due to
trisomy 21

Hx: Smoker for 10 years (tobacco + cannabis),

one glass of wine with dinner, stressful job
WDx: Advanced maternal age.
Recommendation egg donor

Case Study
Dx: Lr fire. Yinwei excess (Yinwei trying to contain the
heat)
Tx: UB63, GB35, GB27 St 28 (30hz for 10 min), TH3,
TH5, Kd 10, Lu6
Drain Lr fire

Result: After 6 treatments the choppiness and heat in

the pulses began to subside but was replaced by an
emptiness in the liver position. Pulse less deviated.
Tx: kd7, kd9 sp15 (2 hz for 5 minutes), kd10, pc7, Lu5
Add herbal medicine: Han Lian Cao 9g, Nu Zhen Zi 9g,
Fu Pen Zi 6g, Wu Wei Zi 6g, Zhi Ke 3g, Zhi Zi 4.5g, no
alcohol for 3 weeks
Result: After 3 treatments (3 weeks) the pulses filled
out. Lu began diffusing, TH reduced, Lr not rapid.

Case Study

Case Study

Tongue remained swollen on right side.

Papules @ root became a dull red.
Pulses: intermittently choppy at blood level in
guan position
Tx: Lr5 (bled), Lr 8, Sp9, CV9, CV4

Result: After 8 treatments pulses completely

balanced except liver pulse slippery and sl.
Rapid. Tongue still swollen on the right side.
Requested patient stop alcohol completely.
After 4 more treatments pulses normalized with
only a slight deviation in guan remaining.

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715

Tel: 626-780-7182 Fax: 626-609-2929 Website: www.eLotus.org Email: [email protected]
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine.

Case Study

Contact Info

REI allowed for another IVF following acu and

resulted in a healthy pregnancy. No change in
quantity of follicles, but quality of embryos
improved dramatically.
During pregnancy Tx: kd 9 moxa (ibuki 1 cone),
Lu5, Lr8 for 1st trimester. Amnio was normal.

Brandon Horn, PhD, JD, LAc

More information on the classic single herbs mentioned in

this seminar/webinar can be found in the
Chinese Medical Herbology and Pharmacology
More information on the classic formulas can be found in
the Chinese Herbal Formulas and Applications

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Tel: 626-780-7182 Fax: 626-609-2929 Website: www.eLotus.org Email: [email protected]
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine.

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