Organ Baths
For conducing ex-vivo studies on isolated tissues
COM
PAC
BA
SI
PRODUCT OVERVIEW
PANLAB s.l.u. provides complete hardware solutions
and associated software for isolated tissues studies
from simple, manual systems to automated, computercontrolled systems.
The Compact Organ Baths series have been designed and
developed to satisfy the requirements of investigators
by offering advanced characteristics that render them
suitable for the in-vitro study of tissue behaviour. Due to
their compact design minimum bench space is required.
The Basic Single Chamber Organ Bath serie was developed
to provide a practical and functional design. They are
used basically in teaching, where their low demanding
maintenance, ruggedness and ease of use guarantee
excellent didactic performance.
All organ baths include tissue holders, transducer holders
and micropositioners.
Panlab provides a broad range of transducers, Ampliers,
digital Stimulators and the Protowin software for data
storage and analysis, including Dose Response analysis.
Please ask for the catalogues!
PANLAB s.l.u.
Key Features
Chambers fully and easily interchangeable.
Positioner for high precision adjustment of
Micro
the Transducer and tissue-holder support.
omplete accessibility to all components to
Cfacilitate
maintenance or replacement.
easy to place the stimulation
Extremely
electrodes.
valves per chamber for the fine
Independent
adjustment of bubbling.
Minimum drift of the nutrient liquid.
of totally inert materials (Viton, TPFE, Delrin,
Use
Silicone) and other materials that are not
Leaflet
Tissue bath studies allow the ex-vivo study of contractile
and relaxatory processes in target tissues. This assay
is commonly used to explore the functioning of a wide
variety of physiologic functions, mostly the cardiovascular,
gastrointestinal, pulmonary and renal functions and
reproduction.
degraded by acids or salts.
APPLICATIONS
Drug screening, classical pharmacology, toxicology,
Cardiovascular diseases, Diabetes, Allergy, Gastrointestinal
and renal dysfunctions, graft inammation, Sepsis,
Cancer...
LF0838B
01
Organ baths
BASIC ORGAN BATH
The Basic Organ bath consists of a Perspex organ bath with a glass tissue
chamber, three-way stopcock for physiological solution exchange, a ne
needle valve for gas regulation and a Micro Positioner with a tissue holder.
and compact individual
Static
assembly.
can be attached to form
They
batteries and work with different
22
tissues, using the same Termo
Regulated Pump.
Three-way PTFE tap for lling
and
emptying with the nutrient
liquid.
Heating coil built into the bath.
with a 25 mL chamber
Supplied
(by default)
18
30
Flat recorder
Work without computer! The Flat Recorder records the signal
on paper.
The transducer is connected directly to the Recorder, without
Ampliers or Couplers
23
30
Dimensions are in centimeters
LE 120-1
LE 120-2
76-0042 Flat Recorder - 1 Channel
76-0043 Flat Recorder - 2 Channels
Dimensions: 26 x 35 x 13 cm
O ring for chamber xing
Valve for bubbling adjustment
3-way PTFE Stopcock
Thermo Regulated Pump
SPECIFICATIONS
The LE13000
LE1300 Thermo regulated
pump is used
use to heat and recirculate
the water that
th maintains a constant
temperature in the tissue chamber.
It can be used to heat up
to 4 single baths, provided
that they are close enough
th
to avert drastic temperature
drops.
dr
02
Temperature range
+3C to 80C (Protection) Room Temperature;
Resolution 0.2C
Flow
12 l/min
Pressure
150 mbar
Total height
53 cm
Power supply
125V or 220 V, 1000 W
Perspex Tank 8 l
32 x 19 x 16 cm
PANLAB s.l.u.
Organ baths
COMPACT ORGAN BATHS
The Compact design allows up to eight individually mounted tissues
sues
to be studied simultaneously and independently per system.
The main perspex reservoir houses the heater, the chambers
and coils, one for each chamber, all submerged in
thermostatetically controlled water.
Others characteristics
design reduces
ces
Compact
space requirements
nutrient
Independent
liquid inputs allow
use of different
physiological
solutions in the same
chamber
All the input output
connections
are accessible on
the rear panel of the bath
modes for solution replacement: overow/
Two
emptying and lling
Turbulence-free water circulation
of safety sensors for both water level and water
Use
temperature (cut-off at 50 C)
heating progressive control system
Electronic
prevents temperature peaks and ensures optimal heat
stability
Available accessories for using continuous perfusion
Components included
180 mL heating coil (one per chamber)
Thermo Regulation Unit
Gas outlet for feeding Petri solution
Micropositioners (one per chamber)
NEW OPTION
Superfusion Accessory LE01090
Input
Trickle
Output
Thermo Regulator
SPECIFICATIONS
Temperature
20C up to 40C
Resolution
0,1C
Stability
0,1C
Measures
24,7 x 11,5 x 16,0 cm
Power supply
125V/220 V, 1000 W
Manual or automatic lling and emptying!
lling and emptying with the nutritive
Independent
solution (Krebs).
Manual serie: three-way tap in the organ baths
serie: electrically-operated valves
Automatic
(two per chamber, one for lling and another for
emptying)
can be operated independently or
Electrovalves
simultaneously pushing the relevant key or by an
external device (timer, programmer or software).
Manual three-way tap
Automatic valves control
Heating
Coil
PANLAB s.l.u.
03
Organ baths
BASIC AND COMPACT BATH FEATURES
Chambers
Panlab s.l.u. provides a calibrate tissues chambers
of 4 different volumes (5, 10, 25 and 50 ml).The
chambers of the Basic Organ Baths do not have
the outlet A.
The Basic Organ Baths are equipped from factory
with a 25ml chamber. By request it can be changed
by another one of different volume.
Compact Organ Baths has not included the
chambers, so they must be ordered separately.
O-Ring
Micro Positioners
Tissue clips
The chambers are holded
on to the bath by two
O-Rings, that allow easy
remplacemet of the
chambers
Each organ bath includes the
Micro Positioners for a ne
adjustment of the tension
applied over the tissue by the
transducer.
Supplied in 10 units packs. Not
included in the bath set
LE0140 CLAMP
The
whole
ensemble
(transducer, tissue holder and
Micro Positioner) can be easily
detached from the Organ Bath
structure to allow an easy
and fast set of the tissue in
conditions that preserve an
optimal safety of tissues.
LE0145 HOOK
Electrodes
Tissue
The stimulation electrodes have a hook for holding the
tissue.
Four models are available in stainless steel or platinum
material.
LE 01.03X-YZ
Ring Diameter (6.5, 8, 10)
Model: A, B, C, o D
0 to Steel/Inox
5 to Platinum
ORDERING INFORMATION
CHAMBERS
COMPACT ORGAN BATHS (Chambers not Included)
Chambers
Dimensions (cm)
Tank
Manual
Automatic
5 mL
LE0105
76-0044
Base: 28 x 20; Height: 27 + 22
5L
LE01002
76-0030
LE01026
76-0031
10 mL
LE0110
76-0045
Base: 44 x 20; Height: 27 + 22
8L
LE01004
76-0032
LE01046
76-0033
25 mL
LE0125
76-0046
Base: 60 x 20; Height: 27 + 22
11 L
LE01006
76-0034
LE01066
76-0035
8 mL
LE0150
76-0047
Base: 76 x 20; Height: 27 + 22
14 L
LE01008
76-0036
LE01086
76-0037
BASIC ORGAN BATHS (Chamber of 25ml by default)
LE11100
76-0165
Single Organ Bath. Thermo Regulated not included.
LE11200
76-0166
Double Organ Bath - Includes Thermo Regulated Pump LE13000
LE11400
76-0167
Quadruple Organ Bath - Includes Thermo Regulated LE13000
LE13000
76-0168
Thermo Regulated Pump
04
PANLAB s.l.u.
