1 - Genetics The Science of Heredity and Variation
1 - Genetics The Science of Heredity and Variation
Introduction
Many similarities and differences in family traits have genetic bases. Sex determination,
the occurrence of sex intermediates, mental retardation, and even infant deformities or death may
have underlying genetic or cytological causes.
Outcomes:
1. Define genetics as a science
2. Narrate the significant events in the history of genetics.
3. Enumerate the scope, fields and applications of genetics
4. Discuss the methods of genetic study
Genetics
History of Genetics
Time Table
460 377 B.C. Believed that each part of the parents body gives off tiny particles
Hippocrates that travel to the gonads to produce an offspring.
384 322 B.C. Presented the same idea as Hippocrates provided it favoured a
Aristotle fluid rather than particles travel to the gonads.
1822 1884 Devised a precise mathematical pattern for the transmission of
Gregor Mendel hereditary units.
1733-1806 Observed that although hybrids between species may show
Kolreuter uniform appearance, their fertile offspring will usually produce
considerable diversity.
1900 Duplicated mendels experiment.
Carl Correns (Germany),
Erick von Tschermak
(Austria), Hugo de Vreis
(Holland)
1902 Bateson, Cuenot Provided the information indicating that Mendels principles also
and Johansen apply to animals.
1902 Indicated the association of the mendelian factors with the
Sutton chromosomes by pointing to the resemblances in behavior
between the two.
1930 Provided basis
G.W. Beadle, B.
Ephrussi, E. L. tatum,
JBS Haldane
The Scope of genetics consists of the following broad problems with which it deals.
Chapter 1
Genetics
1. The development of an individual and maintenance of his own unique inherent pattern in
dynamic interplay with the environment.
2. The ability of species to transfer their systems to the next generation for continued
existence.
3. Living organisms orderly variety of patterns and their changes with time on a zoological
scale constitute the accomplishment of organic evolution.
4. The control of plant and animal improvement through breeding.
5. The definition of similarities and differences in the patterns encountered within the
human species and of the degree of plasticity of these systems.
Field of Genetics
1. Human Genetics
Focused on the pattern of transmission of human traits.
2. Medical Genetics
Area of human genetics focusing on studies of genetic diseases.
3. Cytogenetics
Concerned with how genes are arranged on chromosomes.
4. Microbial Genetics
Genetic investigationson microbes such as bacteria, yeasts, viruses, certain
molds, certain algae and ce tain protozoans.
5. Biochemical Genetics
Investigations focused on the action of genes on the biochemical level.
6. Molecular Genetics
Studies on the molecular level of genes.
7. Population Genetics
Concentrates on the gene pool (gene pool is defined as the sum of all the genes of
a population).
Application of Genetics
1. Experimental Breeding
One of the first methods of genetic investigation
Chapter 1
Genetics
Some organisms are much better united for use in experimental breeding than
others. Some of the qualities that make a species particularly suitable are the
following:
i. Short life cycle
ii. Large number of offspring
iii. Many variable inherited characteristics
iv. Raised conveniently and cheaply
2. Pedigree Analysis
Determine the type of ancestry.
Determine the method of transmission of traits.
Source:
1. Bio D: Geneics UPOU Module
Chapter 1