Cosmetic ingredients

Akema Fine Chemicals S.r.l. Tel. +39 0541 657077 › Fax +39 0541 657134
Via Puglie, 12 › 47853 Coriano (RN) Italy [email protected] › www.akema.it
 Company highlights Distribution network
The products listed in this brochure are Akema has a large network of distributors For more information on products and
available worldwide through our local agents and agents in more than 40 countries services contact us directly or visit our
or from our headquarters in Italy. worldwide. Further information and help finding website at :
the best solution for your needs can be obtained www.akema.it
Additional products are also available or can directly from ourselves or via our agents.
be developed according to specific needs. The complete product documentation package For details on our distribution in your area,
and samples are available upon request. please contact us via phone, fax or e-mail.

» Over 30 years of production experience

» EU manufacture based in Italy

» Complete series of allantoin derivatives

» Wide range of cosmetic preservatives

» Family-owned company

» Worldwide distribution network

» Commitment to customer care

» Microbiological service and challenge tests offered

 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCTS LIST

Company profile

Founded in 1973, Akema Fine Chemicals is a Akema due to decades of experience We are committed to providing a continual
manufacturer of specialty chemicals for the has become a leading manufacturer of support for our customers ranging from
cosmetic and pharmaceutical industry. Imidazolidinyl Urea and Diazolidinyl Urea. assistance with marketing to technical
The company has focused on two main Over the years the company has widened its services.
product lines: range of preservatives to include new mild and The challenge tests which are offered to
» Allantoin and allantoin derivatives alternative preserving systems. customers play an important role in the
» Cosmetic preservatives. selection of preservatives and in determining
Now Akema offers the cosmetic industry a the appropriate level of use.
For more than 30 years Akema has comprehensive range of preservative systems,
successfully supplied both small and large able to meet the challenging needs of the At present Akema is recognized as an
cosmetic and pharmaceutical companies, modern cosmetic market. accredited manufacturer of cosmetic
building up a strong reputation as a reliable ingredients with a long history and an
manufacturer of high-quality Allantoin. Akema is an independent family-owned established presence within the global
company located in Northern Italy with a well marketplace. Akema provides high quality
An exclusive range of Allantoin derivatives established distribution network spread over products and services to successfully serve
is also produced, which offers formulators a the five continents. the global cosmetic industry.
valuable group of safe and effective functional
ingredients for various specific applications. All our products are manufactured in Italy Akema continues to form successful
using the latest technology and monitored by partnerships giving a competitive advantage
our own quality control system. in the current demanding market.
Allantoin
Allantoin is a well recognized skin protectant A pronounced moisturizing effect results organic component of many types of soil.
agent for cosmetic and dermatological from its ability to increase the water binding With a long history of use and no evidence of
preparations. ability of the stratum corneum which in turn adverse effects, allantoin represents an ex-
improves skin appearance. tremely safe and effective cosmetic ingredient,
Allantoin is a valuable healing agent which ideal for modern cosmetic products.
stimulates cell proliferation and healthy tissue Used as an anti-irritant it helps alleviate the In addition it is compatible with a large
formation. Applied to injured skin it promotes skin irritation caused by certain cosmetic number of cosmetic ingredients and has high
the regeneration of damaged epithelium and ingredients such as surfactants, by forming stability in a wide range of conditions.
accelerates wound healing. complexes and neutralizing many irritant and
sensitizing agents. Allantoin is effective in low concentrations.
Allantoin has a mild keratolytic action that It is typically used in the range of 0.1-0.5%,
helps the natural desquamation of the stratum Allantoin as a natural component is found although the concentration can be increased
corneum and promotes soft skin. in many plants, particularly in comfrey roots to 2% as well.
(Symphytum officinale), in animals and as an

Applications: » Baby care As a company focused on Allantoin production

» Skin care (face, lip, body, hands) » Sun care for nearly 40 years, Akema offers specialized
» Hair care » Bath products expertise and the highest quality and purity.
» Shaving products » Oral care Our product arises from a manufacturing
process free from solvents, without the use of
animal or vegetable materials.
 » Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCT LIST

Allantoin EP/USP
Allantoin EP/USP is the pharmaceutical of granulation tissue and accelerates wounds Applications:
grade which conforms to pharmacopeial healing. » Cuts, abrasions, ulcers
specifications (USP, EP and JPC). » Slow healing wounds
Due to its healing and protecting properties As a keratolytic agent it promotes the removal » Burns and sun-burns
Allantoin has found a widespread use in of damaged tissue and dead cells, cleansing » Acne and skin eruptions
various dermatological and veterinary the areas where applied. » Ano-rectal diseases
preparations. » Dermatitis, xerosis, psoriasis
Allantoin can be used in topical drug products » Dental hypersensivity and periodontal
In topical pharmaceutical products it is a at 0.5-2% in the treatment of various diseases.
useful active ingredient which enhances conditions.
cell proliferation, promotes the formation
Allantoin Derivatives Alcloxa
The amphoteric characteristic of Allantoin The aluminum allantoinate complexes INCI name: Alcloxa
permits combination with various chemical combine the well-known properties of
substances to form salts and complexes. allantoin with the astringent action of Aluminium allantoinate complex with mild
aluminium to provide a beneficial effect astringent, anti-irritant, soothing and healing
In combination with various therapeutic in the treatment of acne, oral, foot and action. Well tolerated also by individuals
substances, Allantoin synergizes their activity dermatological problems. prone to irritation, reduce the irritant potential
reducing at the same time their side-effects, of cosmetic and OTC preparations.
sensitizing or irritating properties. Other allantoin complexes provide valuable
The addition compounds and salts thus combinations of allantoin with other active Applications:
formed have been shown to possess useful ingredients which can be useful in various » Antiperspirants, deodorants
dermatotherapeutic properties. specific skin conditions. » Oral care
» Shaving care
» Baby care
» Foot care
» Acne and skin eruptions products
» Anorectal drug products
Use levels: 0.1-2%

Alcloxa A.S. modified

INCI name: Aluminium Chlorohydrex, Allantoin

Alcohol-soluble form of Alcloxa, complexed

with propylene glycol. Designed for use in
high alcohol antiperspirants-deodorants,
pre- and after-shave preparations, aerosols
and lotions. Impart anti-irritant action with a
comfortable sustained drying activity, leaving
a nonsticky film.

Applications:
» Antiperspirants, deodorants
» Shaving care
Use levels: 6-20%

Aldioxa
INCI name: Aldioxa

Aluminium salt of Allantoin with astringent,

soothing and healing properties. Provide a
mild antiperspirant action which serves to dry
up weeping areas, prevents skin irritations
and promotes the regeneration of injured
tissue. Effectively employed to prevent and for
the treatment of diaper dermatitis. Meets JP
specifications.

Applications:
» Antiperspirants, deodorants
» Oral care
» Baby care
» Foot care
» Antiacne and skin eruptions
Use levels: 0.2-2%
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
» Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCT LIST

Alpantha® Allantoin VC®

INCI name: Allantoin Panthenol INCI name: Allantoin Ascorbate

Functional ingredient with anti-inflammatory, Functional ingredient with antioxidant, anti-

soothing, and moisturizing properties. Stimu- aging, bleaching and anti-irritant properties.
lates epithelization and healing of oral mucous Useful to protect from free radicals and UV
and skin impaired functions. Penetrates into damage, for the treatment of signs of aging,
hair with long lasting moisturizing effect, to promote skin renewal and to stabilize
repairs hair damage and improves hair sheen. oxidizable ingredients. Particularly suggested
Wide range of cosmetic and cosmeceutical for anti-aging and aged-skin products, skin
applications to help tissue regeneration and bleaching preparations, sun care and hair
for dry sensitive skin. care.

Applications: APPLICATIONS:
» Hair care » Skin-care
» Sun care » Sun care
» Oral & Lip care » Hair care
» Shaving care USE LEVELS: 0,2-1,0%
Use levels: 1-5%

Almeth®
Alglycera ®
INCI name: Allantoin Acetyl Methionine
INCI name: Allantoin Glycyrrhetinic Acid
Derivative of the sulphur-containing ami-
Functional ingredient with anti-inflammatory, noacid methionine with anti-seborrhoeic,
anti-allergic, mild keratolytic and skin whiten- anti-dandruff, anti-acne and healing proper-
ing properties. Reduces the irritant and ties. Useful in hair products for the treatment
sensitization effect caused by cosmetics, of dandruff and seborrhea capitis. Sooths the
environmental agents and sun exposure, irritated skin and promotes healing of acne
particularly to individuals with skin sensitiv- lesions.
ity. Suitable at 0.1-0.3% for cosmetics and
cosmeceuticals dedicated to dry-sensitive Applications:
skin, skin hyperpigmentation, sun care, shave » Hair care
care and oral care. » Skin care
Use levels: 0.2-1.0%
Applications:
» Skin care
» Sun care Alpolygal®
» Oral care INCI name: Allantoin Polygalacturonic Acid
» Shaving care
Use levels: 0.1-0.3% Functional ingredient with moisturizing,
smoothening and anti-irritant properties.
Suitable for products dedicated to dry, sensi-
tive and aged skin. Improves the skin-feel of
cosmetic formulations.

Applications:
» Skin care
Use levels: 0.5-1.0%

Other allantoin derivatives are also available:

» Allantoin Calcium Pantothenate » Allantoin encapsulated
» Allantoin Benzocaine » Aldioxa VC
» Allantoin Zinc Undecylenate » Aldioxa ACETYL METHIONINE
» Allantoin micronized
Cosmetic preservatives

Due to their nature, cosmetics can support Due to the requirements of the trends in the
the proliferation of microorganisms. current cosmetic market, we offer a variety of
Microbial contamination of cosmetics is a preservation options, ranging from traditional
substantial risk to product quality, consumer actives to systems based on parabens, IPBC
health and regulatory compliance. or organic acids.
An alternative option to traditional
The manufacture of safe cosmetic products preservatives has been developed as well.
includes the use of a tailor-made preservative
system for the protection against microbial This wide range of products will offer the
growth during manufacture, storage and opportunity to find the most appropriate
usage. preservation for every specific need.

Cosmetic formulators require preservatives

which are safe for the consumer and at
the same time inactivate different types of
microbial contaminants.

They should also be compatible with the

formulation, stable throughout the product’s
life, meet the regulations and be in line with
ever changing market needs.
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
» Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCT LIST

Preservative A15 Kemidant Kem 30

INCI name: Imidazolidinyl Urea INCI name: DMDM Hydantoin INCI name: Sodium Hydroxymethylglycinate,
Water
Long history of safe use. Fine white powder White powder with 99% active, highly
highly soluble in water, very active against effective against bacteria and molds at Liquid preservative derived from glycine
Gram+ and Gram- bacteria. Widely used very low levels. Extremely stable to storage with 50% of active in water. Broad spectrum
in cosmetics and topical pharmaceutical conditions and wide pH range. Very soluble in antimicrobial activity, highly effective against
products. Meets USP/NF requirements. water and suitable for a variety of personal Gram+ bacteria, Gram- bacteria and molds.
approvals: EU, USA, Japan1, ASEAN, Brazil care products. Can be used upto pH 12, also useful for the
Use levels: 0.2-0.4%. Approvals: EU, USA, Japan1, ASEAN, Brazil neutralization of carbomer gels and anionic
Use levels: 0.1-0.3% systems. Effective as unique preservative in
many formulations.
approvals: EU, USA, ASEAN, Brazil
Preservative A2 Use levels: 0.2-0.5%
INCI name: Diazolidinyl Urea Kemidant L
INCI name: DMDM Hydantoin, Water
Fine powder highly soluble in water. Highly
effective against Gram+ and Gram- bacteria Clear liquid with 55% of active in water
with some antifungal activity. Suitable in most solution, highly effective against Gram +,
personal care products for rinse-off, leave-on Gram - bacteria, active against molds. Long
and wet wipes. history of use in most type of cosmetics.
approvals: EU, USA, ASEAN, Brazil approvals: EU, USA, Japan1, ASEAN, Brazil
Use levels: 0.1-0.3% Use levels: 0.2-0.5%

Kemidant L40
INCI name: Water, DMDM Hydantoin

Clear liquid with 40% of active in water

solution, highly effective against Gram +,
Gram - bacteria, active against molds. Stable
in wide pH range. Tolerates low storage
temperature. Suitable for the preservation of
most types of cosmetics for rinse-off, leave-
on and wet wipes.
approvals: EU, USA, Japan1 , ASEAN, Brazil
Use levels: 0.3-1.0%
Preservative systems
No single preservative meets the
requirements for a complete preservation in
all situations. Individual preservatives are
often less effective against certain microbial
species than others; most do not have broad
spectrum activity against both bacteria
and fungi. To enhance the antimicrobial
effectiveness, blends of different actives with
complementary activity are used together.

The preservative systems are balanced

combinations of actives, which represents the
best compromise between efficacy, safety and
formulation compatibility.
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
» Preservative systems Microbiological service
» Preservative systems with parabens HAIR CARE
PRODUCT LIST

Preservative systems with parabens

Parabens have been successfully used in
foods, medicines and cosmetics preservation
for more than 70 years. They are the most
widely used antifungals in preserving
compositions for personal care products.
According to US & EU regulatory agencies,
the safety concerns on human health raised
in recent years concerning parabens and
incorrectly amplified by the media, had no
scientific basis.

Methylparaben, Ethylparaben, Propylparaben

and Butylparaben are recognized as safe
and maintain a global approval status in all
cosmetic applications.

Kemaben Kemaben 2E Kemaben 5

INCI name: Propylene Glycol, Imidazolidinyl INCI name: Propylene Glycol, Diazolidinyl INCI name: Phenoxyethanol, Propylene Glycol,
Urea, Methylparaben, Propylparaben Urea, Methylparaben, Propylparaben Methylparaben, Ethylparaben, Propylparaben

Synergistic combination of widely used Liquid preservative system with broad Liquid broad spectrum preservative system active
cosmetic preservatives in liquid form. Broad spectrum activity against bacteria and against bacteria, yeasts and molds. Optimised
spectrum activity against bacteria, yeasts and enhanced activity against yeasts and molds. blend for aqueous and oily formulations.
molds. Suitable for rinse-off, leave-on and Particularly suggested for emulsions very Worldwide approved without limitations; suitable
wet wipes. susceptible to fungal contamination. for rinse-off, leave-on and wet wipes.
approvals: EU, USA, Japan1, ASEAN, Brazil approvals: EU, USA, ASEAN, Brazil approvals: EU, USA, Japan, ASEAN, Brazil
Use levels: 0.6-1.2% Use levels: 0.3-1.0% Use levels: 0.5-1.5%

Kemaben 2 Kemaben 4 Kemaben DHA

INCI name: Propylene Glycol, Diazolidinyl Urea, INCI name: Phenoxyethanol, Methylparaben, INCI name: Phenoxyethanol, Methylparaben,
Methylparaben, Propylparaben Butylparaben, Ethylparaben, Propylparaben Dehydroacetic Acid

The first and most popular preservative blend Liquid preservative system with broad Unique optimized combination with broad
for cosmetics. spectrum activity against bacteria and spectrum activity against bacteria, yeasts and
Most commonly used cosmetic preservative highly effective against fungi. Very popular molds and superior water solubility.
blend. Synergistic combination of widely used combination, widely used for the protection Effective at acidic pH upto 6. Worldwide
cosmetic preservatives in liquid form. Broad of emulsions, oils and wet wipes. Globally approved for rinse-off, leave-on and wet
spectrum activity against bacteria, yeasts and approved for rinse-off and leave-on wipes applications.
molds. Effective in a wide range of cosmetics applications without restrictions. approvals: EU, USA, Japan, ASEAN, Brazil
for rinse-off, leave-on and wet wipes. approvals: EU, USA, Japan, ASEAN, Brazil Use levels: 0.4-1.0%
approvals: EU, USA, ASEAN, Brazil Use levels: 0.2-1.0%
Use levels: 0.5-1.0%
 Allantoin + Allantoin EP/USP » Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE INGREDIENT
PRODUCT LIST

Preservative systems
with IPBC
Iodopropynyl Butylcarbamate, also known as
IPBC, is a highly effective fungicidal agent.
It is widely used in cosmetic preservation
in combination with other antibacterials
to complete the antimicrobial spectrum of
activity. Such blends show synergistic effects,
allowing the use of lower levels of single
preservatives.

IPBC was recently approved for use in

cosmetic products in Japan, gaining
the present status of global approved
preservative.
Effective at very low concentrations, IPBC
represents an alternative to parabens for
products which are very susceptible to fungal
contamination. Largely used in personal care
wipes.

Kemidant Plus
INCI name: DMDM Hydantoin,
Iodopropynyl Butylcarbamate

Powder form, synergistic combination

highly effective against bacteria, yeasts and
moulds. Cost effective alternative to be used
alone in most types of cosmetics, particularly
for rinse-off products.
Approvals: EU 2, USA, Japan 1, ASEAN 2, Brazil
Use levels: 0.1-0.4%

Kem Plus Kem Plus 2

INCI name: Phenoxyethanol, INCI name: Phenoxyethanol,
Iodopropynyl Butylcarbamate Iodopropynyl Butylcarbamate

Liquid preservative system based on the Liquid preservative system with broad
antifungal IPBC, highly active against yeasts spectrum activity against bacteria, yeasts
and molds. Effective alternative to parabens, and molds. Versatile alternative to parabens-
useful for the protection against fungal based system suitable for the protection of a
contamination of a wide range of cosmetics wide range of cosmetics for rinse-off, leave-
for rinse-off, leave-on and wet wipes. on and wet wipes.
Approvals: EU 2, USA, Japan, ASEAN 2, Brazil Approvals: EU 2, USA, Japan, ASEAN 2, Brazil
Use levels: 0.02-0.4% Use levels: 0.5-0.9
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives » Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE INGREDIENT
PRODUCT LIST

Preservative systems
with organic acids
Organic acids are organic compounds with membrane and inhibit the microbial growth. Kemidant K
weak acidic properties, which are widely With a long history of safe human use and INCI name: DMDM Hydantoin, Water,
represented in nature as constituents of global approval, they provide an interesting Potassium Sorbate
plants. alternative which is becoming popular for the
preservation of cosmetics. Highly active preservative blend with broad
Organic acids and their salts are largely used spectrum antimicrobial activity against
in foods, medicines and cosmetics. Organic acids and their salts, together with bacteria, yeasts and moulds. Stable and
benzyl alcohol, are the only preservatives cost-effective system for the protection of a
They are mainly antifungal agents effective permitted by organic & natural certification wide range of cosmetics in acidic condition
in formulations with acidic pH, because bodies. preferably up to pH 6. Suitable for rinse-off,
only the undissociated form present in leave-on and wet wipes.
acidic conditions, can pass through the cell Approvals: EU, USA, Japan1, ASEAN, Brazil
Use levels: 0.2-0.6%

Kem K
INCI name: Phenoxyethanol, Water,
Potassium Sorbate

Mild and skin-tolerable preserving blend with

broad spectrum activity against bacteria,
yeasts and molds. Effective alternative in
cosmetic preservation, can be used for
the protection of a wide range of personal
care products with a slightly acidic pH,
preferably up to 6. Globally allowed for use in
cosmetics and dermopharmaceuticals with no
application restrictions.
approvals: EU, USA, Japan1 , ASEAN, Brazil
Use levels: 0.5-1.2%

Kem E
INCI name: Benzyl alcohol, Water,
Potassium Sorbate, Sodium benzoate

Liquid preservative with broad spectrum

efficacy based on natural-identical
ingredients. Gentle on the skin, preserving
combination highly effective against bacteria,
yeasts and molds in acidic conditions up to
pH 5.5. Globally approved in rinse-off and
leave-on applications, it is suitable for use in
a wide variety of cosmetic products. Permitted
for the preservation of natural & organic
cosmetics by main certification standards
(Ecocert, BDIH, Soil Association, ICEA/AIAB).
Approvals: EU, USA, Japan, ASEAN, Brazil
Notes on regulatory status: (1) Allowed in rinse-off products, not to be used on mucous membrane
(label required).
Use levels: 0.5-1.2%
All listed preservatives are approved according to EU Cosmetics Directive (2) Allowed in bath products, shower gels and shampoos without
and US regulation. restrictions; in other rinse-off products can’t be used for children under 3
Restricted concentrations, warnings, application restrictions are years (label required). Allowed in leave-on products not for use on large
applicable. Please refer to the product documentation for more specific part of body and not for children under 3 years (label required).
information. Not to be used for oral-care and lip-care.
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives » Multifunctional system with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCT LIST

Multifunctional system
with antimicrobial properties
Stabil Stabil is globally approved for all applications, As a combination of well established and
INCI name: Phenethyl alcohol, Caprylyl Glycol doesn’t contain ingredients commonly safe cosmetic ingredients with excellent
recognized as preservatives and the antimicrobial performance, Stabil offers
Stabil is an innovative multifunctional formulated producted may be described as formulators a different modern concept, which
system which represents a reliable and safe being preservative-free. meets current consumer and market demands
alternative to the traditional preservatives for alternative preservation strategies.
for personal care. Clear, colourless liquid compatible with the
It is a combination of widely accepted most used cosmetic ingredients and effective
cosmetic ingredients which acts as a skin in a wide range of pH and temperature. It is a
moisturizer, wetting agent and mild fragrance. versatile system that can be used at 0.6-1.2%
in a wide range of personal care applications,
Furthermore it has a broad spectrum activity particularly recommended for individuals with
against bacteria, yeasts and moulds, which sensitive skin and in baby care.
allows the control of microbial growth.
It is therefore an ideal option for creating No further preservatives are normally required
mild and skin-compatible self-preserving in the appropriately formulated product.
cosmetics.
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems » Microbiological service
Preservative systems with parabens HAIR CARE
PRODUCT LIST

Microbiological
service
Every cosmetic formulation has unique This test is also referred to as the To meet these specific needs of cosmetic
preservative requirements which depend challenge-test. It typically consists of the manufacturers, our in-house microbiological
on many factors such as the chemical addition of standardized inocula of bacteria laboratory offers its experienced technical
composition, the physical form, the intended yeast and moulds to the product sample. support.
use and the type of container. The surviving microorganisms are estimated
during a 28-day incubation period at different The challenge tests are offered to customers
This complex environment and its many time intervals, then results are compared with to assess the adequate preservation of each
interactive possibilities, makes it difficult established acceptance standards. cosmetic formulation, compare the activity
to predict with precision the ultimate of different preservatives and finally find the
effectiveness of a preservative in the final The purpose of conducting a challenge-test is appropriate level of use.
product. to select the appropriate type of preservative This test is performed according to a modified
and to determine the optimal level which European Pharmacopoeia method.
It is therefore necessary to conduct a direct ensures a safe preservation without excess.
microbiological preservative-effectiveness In this way, the preservative concentrations Our microbiologists may also assist
test on the finished formulation to confirm are kept as low as possible in order to customers during formula development and
that the preserved product may withstand the improve skin compatibility, avoid adverse help solve preservation issues with existing
microbial contaminants it might meet during reactions and unnecessary costs. preservative systems.
production and consumer use.
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional systems with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens » HAIR CARE
PRODUCT LIST

Hair care
Glyoxylic acid 50
INCI name: Glyoxylic Acid, Water

Hair care ingredient with hair straightening,

relaxing and conditioning effects.
The carboxylic and aldehyde groups of
glyoxylic react with the amine groups present
in hair keratin, resulting in the formation of
a stable amine bond. Provides long lasting
straightening effect of hair fibres in a very
short period of time, without causing damage
to the hair and skin irritations typical of
hydroxide-based products.

Organic acid with 50% of active in water

solution, miscible in water and alcohols, free
from formaldehyde and glutaraldehyde.

Functional cosmetic ingredients suggested in

hair straighteners to relax tightly curled hair,
soften or loosen curls, in particular for the
treatment of ethnic and fuzzy hair (shampoos,
conditioners, lotions, creams).
Used as a pH adjusting agent to neutralize
cosmetic formulations with high pH.

APPLICATIONS:
» Hair care products
USE LEVELS: 0.5-10%
 Allantoin + Allantoin EP/USP Preservative systems with IPBC
Allantoin derivatives Preservative systems with organic acids
Cosmetic preservatives Multifunctional system with antimicrobial properties
Preservative systems Microbiological service
Preservative systems with parabens HAIR CARE
» PRODUCT LIST

Product list
Product name INCI name

Allantoin ALLANTOIN Allantoin

ALLANTOIN EP/USP Allantoin (Ph. Eur., USP, JPC name)

Allantoin derivatives ALCLOXA Alcloxa

ALCLOXA A.S. MODIFIED Allantoin, Aluminum Chlorohydrex
ALDIOXA Aldioxa
ALPANTHA Allantoin Panthenol
ALLANTOIN CALCIUM PANTOTENATE Allantoin Calcium Pantothenate
ALGLYCERA Allantoin Glycyrrhetinic Acid
ALLANTOIN VC Allantoin Ascorbate
ALMETH Allantoin Acetyl Methionine
ALPOLYGAL Allantoin Polygalacturonic Acid

Hair care GLYOXYLIC ACID 50 Glyoxylic Acid, Water

Preservative actives PRESERVATIVE A15 Imidazolidinyl Urea

PRESERVATIVE A2 Diazolidinyl Urea
KEMIDANT DMDM Hydantoin
KEMIDANT L DMDM Hydantoin, Water
KEMIDANT L 40 Water, DMDM Hydantoin
KEM 30 Sodium Hydroxymethylglycinate, Water

Preservative systems KEMABEN Propylene Glycol, Imidazolidinyl Urea, Methylparaben, Propylparaben

KEMABEN 2 - KEMABEN 2E Propylene Glycol, Diazolidinyl Urea, Methylparaben, Propylparaben
KEMABEN 4 Phenoxyethanol, Methylparaben, Butylparaben, Ethylparaben, Propylparaben
KEMABEN 5 Phenoxyethanol, Propylene Glycol, Methylparaben, Ethylparaben, Propylparaben
KEMABEN DHA Phenoxyethanol, Methylparaben, Dehydroacetic Acid
KEMIDANT PLUS DMDM Hydantoin, IPBC
KEM PLUS - KEM PLUS 2 Phenoxyethanol, IPBC
KEMIDANT K DMDM Hydantoin, Water, Potassium Sorbate
KEM K Phenoxyethanol, Water, Potassium Sorbate
KEM E Benzyl alcohol, Water, Potassium Sorbate, Sodium Benzoate

Self-preserving STABIL Phenethyl Alcohol, Caprylyl Glycol

alternative
Distribution network
Our products are available worldwide through Akema has a large network of distributors and The complete product documentation packet
our local agents or from our headquarters in agents in more than 40 countries worldwide. and samples are available upon request.
Italy. Additional products are also available or Further information and help finding the For more information on products, services
can be developed according to specific needs. best solution for your needs can be obtained and distribution in your area, please contact
directly from ourselves or via our agents. us directly or visit our website

www.akema.it

North America EUROPE Slovenia MIDDLE EAST ASIA PACIFIC

Canada Bosnia Spain & SOUTH ASIA Indonesia
USA Bulgaria Sweden Bangla Desh Malaysia
Croatia Switzerland India Myanmar
LATIN AMERICA Finland Turkey Iran Philippines
Argentina France United Kingdom Israel Singapore
Brazil Germany Turchia Pakistan South Korea
Chile Greece Saudi Arabia Taiwan
Colombia Italy Syrya Thailand
Ecuador Poland Vietnam
Guatemala Portugal AFRICA
Paraguay Romania Egypt OCEANIA
Uruguay Russia South Africa Australia
Venezuela Serbia Tunisia Nuova Zeland
 Cosmetic ingredients

Akema Fine Chemicals S.r.l. Tel. +39 0541 657077 › Fax +39 0541 657134
Via Puglie, 12 › 47853 Coriano (RN) Italy [email protected] › www.akema.it