Radiation Safety Manual PDF
Radiation Safety Manual PDF
Radiation Safety
Manual
1
CONTENTS
1. Introduction
9. Statutory Requirements
9.1 Commonwealth Recommendations
9.2 The Victorian Requirements
9.3 Major Requirements of the Health (Radiation Safety) Regulations,
1994
2
11. Monitoring
11.1 Introduction
11.2 Types of Monitoring
11.3 Calibration and Performance Checking
11.5 Choice of a Monitoring Instrument
11.6 Types of Instruments for Measuring Ionising Radiation
17. Procedures for ordering, purchasing and receipt of sources of ionising radiation
17.1 Introduction
17.2 Ordering and Purchasing
17.3 Receipt of Radioactive Material
3
19. Incidents Involving Ionising Radiation
19.1 Introduction
19.2 Definition of an Incident
19.3 Emergency Procedure
19.4 Emergency Equipment
19.5 Specified Actions to be taken by RSOs and Deputy RSOs for
Particular Incidents
19.6 Decontamination
19.7 Incident Reporting, Investigation and Recording
Glossary
Appendix A Manual for Users of Ionising Radiation
Appendix B Statutory Documentation for Ionising Radiation
Appendix C Sample Calculations on Ionising Radiation
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1. INTRODUCTION
This manual has been produced, to provide practical guidelines for all persons who may come
in contact with ionising radiation, to comply with Monash University's (also referred to as "the
University") Ionising Radiation Safety Policy Statement (OHS Policy No. 1/92 an hereafter
referred to as the "Policy Statement"). The manual has been developed in accordance with the
requirements of sections 18 and 19 of the Policy Statement and is intended as a reference source
for Radiation Safety Officers and Deputy Radiation Safety Officers.
Appendix A of this manual contains the truncated manual "Manual for Users of Ionising
Radiation" which is intended for other radiation workers. The policy requires strict compliance
with relevant Victorian and Commonwealth Government legislation, codes of practice,
Australian Standards, and recommendations from the International Commission on Radiological
Protection (ICRP) and the National Health and Medical Research Council (NH&MRC).
It is stressed that this manual must be read in conjunction with the Policy Statement. A copy of
the Policy Statement can be obtained from the department Radiation Safety Officer.
The risk of prosecution by the Department of Health and Community Services or the Health and
Safety Organisation of Victoria exists if compliance with all applicable legislation is not
fulfilled. In addition, common law actions by individuals against the University for negligence
can be based on the allegation of breach of the statutory "duty of care" (in accordance with
section 21 of the Occupational Health and Safety Act 1985). Furthermore, failure of the
University to give a high priority to compliance with all regulatory requirements in the radiation
protection area could invite a negative response including public criticism, adverse media
publicity and legislative curtailment of its activities.
5
2. RESPONSIBILITY FOR IONISING RADIATION SAFETY AT MONASH UNIVERSITY ... 7
6
2. RESPONSIBILITY FOR IONISING RADIATION
SAFETY AT MONASH UNIVERSITY
Ultimate responsibility for ionising radiation safety rests with the University Council.
However aspects of this responsibility are delegated throughout the University structure
as shown in Figure 1.
MONASH UNIVERSITY
COUNCIL
↓
OCCUPATIONAL HEALTH AND SAFETY POLICY
COMMITTEE
↓
OCCUPATIONAL HEALTH SAFETY &
ENVIRONMENT
↓
RADIATION PROTECTION OFFICERS
↓
DEANS
↓
HEADS OF BUDGETARY UNIT
↓
RADIATION SAFETY OFFICERS AND DEPUTY RADIATION SAFETY
OFFICERS
↓
SUPERVISORS
↓
INDIVIDUALS
7
2.2 The Role of Individual Members of the Structure
The University Council has ultimate responsibility for ionising radiation safety at
Monash University. Their primary function in relation to ionising radiation safety is to
choose the direction and extent of change within the University environment. On a
more practical level they must approve all policies on ionising radiation safety prior to
their enactment.
The OHSPC has been charged with the primary responsibility of advising the
University Council on occupational health and safety matters. It is comprised of
employer nominees, employee nominees including representatives of all the major
unions, several observers and a secretary who is provided by the Occupational Health
and Safety Branch.
The major responsibilities of the OHSPC in relation to occupational health and safety at
the University are; ensuring a uniform approach to health and safety issues throughout
the University, formulating and reviewing policies and procedures, monitoring
compliance with statutory and in-house requirements, monitoring the performance of
facilities, departments, centres, units and branches and facilitating cooperation between
the University and its employees.
The OHSE is the body within the University holding most of the occupational health
and safety expertise. In practical terms, OHSE is responsible for the instigation of all
occupational health and safety programs, training, policies and procedures, advice and
other matters. The Radiation Protection Officers are members of OHSE. The OHSE
should be contacted to deal with occupational health and safety issues that a supervisor,
health and safety representative or departmental specialist officer (radiation, laser,
biosafety or safety) cannot deal with.
8
Position Person Phone Number
Manager Mr Paul Barton 54049
Radiation Protection Ms Margaret Rendell 51060
Officer
Assistant Radiation Mr Sam Zouzounis 54059
Protection Officer
OHSE Consultants
(Medicine) Dr Simon Barrett 55739
(Science) Ms Sharon Lockhart 51627
(Engineering) Mr John Whale 51021
The numbers listed above are the extension numbers. If you cannot ring these types of
extension numbers then you will need to add 990 in front of the numbers listed to contact
OHSE.
In accordance with the requirements of the Policy Statement and the Health Act of
1958, the University must have the equivalent of a full time RPO. A full position
description for the RPO including responsibilities, duties and authority conferred is
included in the Policy Statement. In summary the RPO/s are the University’s in-house
experts on radiation safety and representatives who communicate with the Health
Department of Victoria on all radiation safety matters. The RPO should be consulted
when the Departmental Radiation Safety Officer or deputy is unable to answer any
query on radiation safety.
The names and contact numbers of the RPOs are included in section 2.2.3.
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2.2.5 Deans
The dean of a faculty does not directly contribute to radiation safety matters within
departments, as this is the responsibility of department heads. However, the dean will
at times receive communications on general radiation safety matters in the form of
general directives from the Manager of OHSE or a higher authority.
Heads of budgetary units have the most responsibility for radiation safety of individual
radiation workers, non-radiation workers and members of the public who are under their
jurisdiction. They are responsible for appointing radiation safety officers and deputies,
putting into place all directives from higher authorities in relation to radiation safety and
delegating duties or authority in relation to radiation safety. A full description of the
duties of heads of budgetary units is included in the Policy Statement.
The RSOs and deputy RSOs are the radiation safety experts at the departmental level.
These positions are best suited to either academic or general staff with considerable
experience in working with ionising radiation, although senior students may be
permitted to take this role under some circumstances. At the current time, the RSOs
and deputy RSOs are also responsible for non-ionising radiation safety.
The RSOs and deputy RSOs are responsible for enacting university policies, procedures
and other directives at the departmental level, assisting individuals with queries on
radiation safety matters and liaising with the RPOs. A full position description for the
position of RSO or deputy RSO, including responsibilities, duties and authority
conferred is included in the Policy Statement.
2.2.8 Supervisors
As with all occupational health and safety issues, supervisors have immediate
responsibility for the safety of their subordinates who are using ionising radiation. They
may be delegated responsibilities by the RSO or deputy RSO. These responsibilities
may include information dissemination, checking procedures, and contamination
monitoring. When a query in relation to ionising radiation safety is raised, the
supervisor should always be the first point of contact in resolving the issue. A detailed
description of the responsibilities of supervisors in relation to ionising radiation safety is
set out in the Policy Statement.
10
2.2.9 Individuals
All individuals within a department that uses or stores ionising radiation are required by
the Policy Statement to behave in a responsible manner and to obey instructions given
in relation to their safety in the presence of ionising radiation. Full details of the
responsibilities of individuals are contained in the Policy Statement. Individuals
working with ionising radiation within the department should receive some training in
ionising radiation safety as part of the requirements of the Policy Statement.
2.3.1 General
In relation to ionising radiation safety their role is rarely that of a technical expert.
However, as they are very familiar with correct procedures for dealing with health and
safety issues they are an excellent point of call when an RSO or Deputy RSO is
unavailable.
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2.3.3 Safety Officers
Safety officers are appointed by heads of budgetary units, and may obtain many of their
directives from their Zone Occupational Health and Safety Committee. They are
usually general or academic staff with a good general knowledge of safety issues and a
thorough knowledge of the department in which they work. They generally liaise
extensively with OHSE, individuals and their Zone Occupational Health and Safety
Committee. The role of a departmental safety officer is detailed in the University's
Occupational Health and Safety Policy Statement.
In relation to ionising radiation safety, the role of a safety officer is rarely that of a
technical expert. However, as they are very familiar with correct procedures for dealing
with health and safety issues and are general safety experts, they are an excellent point
of call when an RSO or Deputy RSO is unavailable.
The terms of reference for zone occupational health and safety committees are
described in the Occupational Health and Safety Policy Statement. In relation to
ionising radiation safety these committees serve to bring together the expertise of RSOs,
deputy RSOs, safety officers, health and safety representatives and senior staff members
within the department. In particular, they have an important role to play in the
discussion and followup of incidents involving ionising radiation, or for provision of
advice on the implementation or development of ionising radiation safety policies and
procedures.
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3. THE FORMATION OF IONISING RADIATION ....................................................................... 14
3.3. ACTIVITY.......................................................................................................................................... 16
3.5.2.2 X radiation 23
13
3. THE FORMATION OF IONISING RADIATION
All matter as we know it is made up of ATOMS. For example, your desk, chair,
telephone, clothes and the food you eat are all made up of atoms. The smallest single
entity of each of these objects is an atom.
There are 106 different types of atoms known to man and these are called
ELEMENTS, each has its own symbol. Examples of different elements are shown in
Figure 2.
Element Symbol
Hydrogen H
Carbon C
Zinc Zn
Iodine I
All atoms of an element are tiny, measuring only fractions of a metre in diameter.
Hydrogen is the smallest atom and measures approximately 0.3 x 10-10 metres in
diameter. Scientists believe that atoms look like a miniature solar system where the
nucleus of each single atom within an element, is orbited by a number of single charge,
negative particles called ELECTRONS (e-).
Electrons exist in SHELLS, which are at varying distances from the nucleus. The
SHELLS most distant from the nucleus contain electrons with the highest energy.
To balance the negative charge of the electrons, the nucleus of the atom contains
positively charged particles called PROTONS (H+) and these are held in close
proximity by NEUTRONS (n). A proton and a neutron are both defined as having an
ATOMIC MASS UNIT (amu) of 1. The specific identity of an element is dependent
on the number of protons held within each atom. The hydrogen atom is the simplest of
all the elements and contains 1 proton and 1 electron. It is shown in Figure 3 beside the
iodine atom which contains 53 protons, 74 neutrons and 53 electrons:
14
Hydrogen Iodine
When a number of atoms of the same or different elements are bonded together, they
form a MOLECULE or COMPOUND. There are millions of molecules known and
they range in size from little more than an atom, to large enough to be viewed through a
powerful microscope. DNA is a molecule, other examples of molecules are shown in
Figure 4.
H H Cl Cl
A neutral atom consists of neutrons, protons and electrons. The nucleus of the stable
atom is held together by attractive forces between the protons and neutrons, which must
be strong enough to overcome the repulsive forces between the protons. Because of this
repulsive force, the ratio of neutrons to protons increases for stable isotopes as the
atomic number increases.
For a variety of reasons, a particular element may contain atoms having different
numbers of neutrons but the same numbers of protons. These different types of atoms
15
of a single element are called ISOTOPES and they are listed for the element hydrogen
in Figure 5.
Isotope Composition
Hydrogen gas 1 proton, 1 electron and 1 neutron
Deuterium 1 proton, 1 electron and 2 neutrons
Tritium 1 proton, 1 electron and 3 neutrons
The exact reasons for radioactivity are not well understood. However, it is believed that
an excess or deficiency in the number of neutrons confers instability within a nucleus.
Radioactivity leads to the emission of alpha (α), beta (β), gamma (γ) or
X-rays or neutrons in a continuing process (chain) until a final stable decay product is
reached.
Given that the most desirable state for any atom is stability, the atoms of isotopes with
excess numbers of neutrons will undergo radioactive decay and emit radiation until they
attain stability. The types of radiation may include alpha, beta, gamma and X-rays.
These represent the emission of differing amounts of energy and mass from the atoms.
The most well known radioactive decay chain is that of uranium-238. Each step in
figure 6 shows the type of radiation that is lost.
α β β α α
238 234 234 234 230 226
92U → 90Th → 91Pa → 92U → 90Th → 88Ra
↓α
β β α α
214 214 214 218 222
84Po ← 83Bi ← 82Pb ← 84Po ← 86Rn
α↓
β β α
210 210
82Pb→ 83Bi → 84Po→ 206
210
82Pb (stable)
α↓ β
206
81Tl
It should be noted that whether the process of radioactive decay is artificially induced or
naturally occurring, the rules for the decay are the same in both instances.
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3.3 Activity
1 Bq = 1 dps
1 Ci = 3.7 ´ 10-10 Bq
The process of radioactive decay is an exponential process and is described by the
formula:
At = Ao e-λt
Where: Ao is the original activity
At is the activity at time t
λ is the radioactive decay constant
Time
Figure 7: The pattern of radioactive decay
The HALF-LIFE (t1/2) of a radioisotope is defined as the time for a known quantity of
an isotope to decay to half of its original activity (Ao). Half-life is determined from the
equation:
t½ = 0.693
17
λ
or if λ is unknown: At = Ao e-0.693/t½
At = Ao
2n
Ao
½Ao
A = Aoe-λt
¼ Ao
1
/8 Ao
1
/16Ao
18
3.5.1.1 Alpha radiation (α decay)
Range: Typically alpha particles travel only a few centimetres in air and
only a few millimetres within tissue or paper. For example a 3.5
MeV alpha particle will travel approximately 20 millimetres in air
and 0.003 millimetres in tissue.
Speed: Speed at a specific time will depend on the energy of the specific
α particle, and how far it has traversed through matter. Initial
speed depends on the energy of the radiation and typical speeds
are in the range of 109 cm/sec. Alpha particles slow and
eventually stop in their passage through matter as they give up
their energy.
Ionising potential: The greatest ioniser of all radiation types due their high linear
energy transfer (LET) potential. A single 3.5 MeV alpha particle
will produce approximately 105 ion pairs in air before coming to
rest.
Formation: Beta decay may occur in any nuclear species that has an excess of
neutrons, irrespective of its mass. Beta particles are always
emitted alone and result in an increase in the number of protons as
a neutron is transformed into a proton and an electron.
19
32 30
e.g. 15P → 14Si + e-(β)
Speed: Initial speeds are in the vicinity of 1010 cm/sec, this is slightly faster
than alpha particles. The speed of the beta particle is attenuated by
the medium through which it travels until the particle comes to a
complete halt.
Range: In general a few metres in air and a few centimetres in tissue. They
have a range higher than most alpha particles and lower than most
gamma rays. For example, a 3.5 MeV beta particle will travel
approximately 11 metres in air and 15 millimetres in tissue.
The formulae for the ranges of beta particles are complex. A good
"rule of the thumb" for the higher energy beta particles, is:
R ≅ 0.5 Emax
Ionising potential: A significant ioniser with reduced LET when compared to an alpha
particle. Beta particles produce ionisation by interacting with
electrons in atomic or molecular orbits.
Energies: The energy of the beta particle may be any value up to that of the
total energy (Emax) of the transformation (continuous energy
distribution). The range of energies typically seen is from 1000 eV
to 5 MeV. The difference between Emax and the beta particle
energy is carried off by another particle called a NEUTRINO.
Neutrinos have no relevance to radiation protection. Only a small
fraction of the beta particles given off from the decay of a particular
nuclide will have energies of Emax. The most probable beta energy
= 1/3 Emax.
20
Figure 9: Energy spectra for β-radiation
Range: In human tissue, the average distance of penetration varies from 0.6
centimetres to nearly 10 centimetres depending on the energy of the
neutrons.
Speed: All neutrons start life as fast neutrons. They are slowed down by
either elastic or inelastic collisions with nuclei of absorber atoms.
The average speed of a neutron varies between 103 - 106 m/s.
Range: Gamma radiation has the largest range of all radiation types.
Gamma photons will travel indefinite distances unless intercepted
by a medium having atoms that will interact to take up the energy
and extinguish the radiation. Gamma radiation will pass right
through the human body and travel for many metres in air unless
blocked by a suitable shield.
Speed: Gamma rays do not slow as they travel through matter. Their
speed (c) is always that of light. i.e. 3 x 108 ms-1 or
18,600 miles s-1.
They will come to a stop only when they lose sufficient energy
through interactions with atoms. The speed of electromagnetic
radiation is related to its frequency and wavelength as follows:
c = fλ
Ionising potential: Gamma radiation causes little ionisation within any medium that it
passes through when compared with the particulate radiations. It
has low LET. Ionisation due to gamma is due to secondary
ionisation by the mechanisms of photoelectric effect, Compton
effect or pair production. (see section 4)
22
Energies: Energies vary from approximately 1000 eV to 10 MeV. Energy
obeys Planck's law:
E = hf (eV)
3.5.2.2 X radiation
23
This mechanism of X ray production is of importance in
commercial X ray machines. The removal of the inner shell
electron from an atom in the initial stages of X ray production
may be brought about in several different ways:
Speed: X rays do not slow as they travel through matter. Their speed is
always that of light as they are an electromagnetic radiation form,
i.e. 3 x 108 m/sec. They will come to a stop only when they lose
energy through interactions with atoms.
Ionising potential: X radiation causes little ionisation within any medium that it passes
through when compared with the particulate radiations. It has low
LET. Ionisation due to X is exclusively due to secondary
(indirect) ionisation by one of the processes of photoelectric effect,
Compton effect or pair production (see section 4).
24
4. THEORY OF INTERACTION OF RADIATION AND MATTER ............................................ 26
25
4. THEORY OF INTERACTION OF RADIATION
AND MATTER
Mechanism: The mode of interaction between a charged particle and the atoms of any
involved medium is one of inelastic collision. Outer shell electrons are always the part
of the atom that participates in such a collision and they may be in inner or outer shell
positions. Such a collision of the electric fields of two charged particles (but not the
particles themselves) results in one of two outcomes:
• Ionisation: The electron is expelled from the atom resulting in ionisation. This is
common where alpha is the charged particle that participates. The large mass and
charge of an alpha particle will ensure complete ionisation of the atom. The free ion
then pairs up with an ion of opposite charge in order to gain neutrality.
Ionising Particle
Negative Ion
+
N + N
+ + +
N + N
+ N N
N
Positive Ion
• Excitation: The electron may simply gain sufficient energy from the collision to
proceed to a higher energy shell, which is further out from the nucleus. This puts the
atom in an excited state. The electrons in the atom may then rearrange in order to
26
return the atom to the ground energy state. This often results in the emission of X
radiation of discrete frequencies.
• The photoelectric effect: A low energy gamma photon (less than 1 MeV) interacts
with a tightly bound, inner shell electron of a heavy atom, e.g. Lead. The ejected
electron assumes the entire energy of the now non-existent photon and travels out to
effect secondary ionisation. The vacancy is usually filled by rearrangement of an
outer electron to the space in the inner shell and emission of one or more frequency
characteristic X rays.
hυ
27
• Compton scattering: Gamma rays of energy 0.2 to 5 MeV may undergo an elastic
collision with a loosely bound outer electron of an atom having an intermediate mass
e.g. Iron. Only some of the photon's energy is taken up in ejecting the electron from
the atom and the photon is also scattered with reduced energy and a longer
wavelength. The ejected electron may go on to produce secondary ionisations.
hυ1
hυ0
θ
Scattered
electron
• Pair production: A gamma photon having an energy greater than 1.02 MeV may
interact with the electric field surrounding a heavy nucleus (e.g. lead) and give up its
energy to form and electron and a positron (positively charged electron; the
formation of which is beyond the scope of this manual). These two particles lose
energy in the process of secondary ionisation. The positron may then interact with
another electron in a process called ANNIHILATION. The two particles convert to
two gamma rays of 0.51 MeV each and travel in opposite directions to one another.
hv1 = 0.51MeV
Electron
+
+
Positron
N + N
hvo > 1.02MeV ++ N + hv1 = 0.51MeV
photon N + N +
28
4.3 Neutron Interactions
Mechanism: The interactions that occur between neutrons and the atoms of involved
materials are of the billiard ball type and involve direct contact between
the neutron and the atom (nucleus in particular). There are three
different types of collisions:
• Elastic scattering: This is the predominant mode of interaction for fast neutrons that
interact with light nuclei. The neutron continues on after the collision with a reduced
energy and changed direction. The energy lost by the neutron has been totally
transferred to the atom in the form of kinetic energy and the atom moves according
to its new energy.
n
Nucleus
• Inelastic scattering: When neutrons collide with the nuclei of heavy atoms a
proportion of the neutron's energy is imparted to the atom's nucleus which becomes
excited. The neutron will be deflected off in another direction with reduced energy.
The nucleus de-excites almost immediately by emitting a gamma photon (Diag. 7).
n
n
Excited Nucleus
Nucleus
γ
Normally emits
excess energy in
form of γ-rays
Figure 16: Inelastic Scattering
29
• Capture: This is the predominant mode of interaction for thermal neutrons. When
they collide with the nucleus of the involved atom, they become part of it thus
elevating the nucleus to an excited state. The nucleus of the atom usually responds
by emitting gamma rays in order to return to the ground state. In some cases alpha
or proton emission or fission may occur. This process may render an inappropriately
chosen shielding material radioactive after exposure to neutrons.
30
5. THE INTERACTION OF IONISING RADIATION WITH BIOLOGICAL MATTER .......... 32
31
5. THE INTERACTION OF IONISING RADIATION
WITH BIOLOGICAL MATTER
Ionising radiation adversely affects human tissue by causing ionisation within the
molecules of that tissue. Commonly the first molecule to be involved is water and ions
are produced that carry single positive or negative charges. The first reaction that
occurs is usually:
This is followed by interaction between the hydronium ion and the electron and other
water molecules resulting in a variety of new products including; H+ (hydrogen ion),
OH- (hydroxyl ion), H· and OH· (hydrogen and hydroxy radicals). The hydrogen and
hydroxyl ions take no further part in further reactions, but the hydrogen and hydroxy
radicals may interact with themselves or other molecules. For example, two hydroxy
radicals may react to form hydrogen peroxide.
The radicals and hydrogen peroxide can then react chemically with, and consequently
alter, important molecules within human cells. This process of ionisation and the
concomitant heating of the cell contents may either destroy the cell outright at the time
or result in changes to the genetic material within the cell. These changes come about
as a result of the ions reacting with DNA in the cell nucleus.
A living human cell can be thought of as having metabolic, functional and usually
reproductive activity. Only cells from the central nervous system (neurones and parts of
the spinal chord) and the female germ cells do not reproduce, and are therefore not
replaced. Other cells such as those of the liver reproduce very slowly. For the purposes
of ionising radiation safety, death of a cell is regarded as the inability of that cell to
reproduce due to the effects of the ionising radiation.
Where the cell is not killed by the initial exposure to ionising radiation, other conditions
may result such as; blocked or delayed cell division or transmission of a mutated gene
to the progeny. In many cases, a damaged cell may be prevented in its first or later
attempts to reproduce.
32
Low LET radiation (X, gamma and beta) tends to inflict more sublethal damage that
can be repaired at a later stage than high LET radiation (alpha and neutrons). It
transfers relatively little of its energy to the tissue per unit path length, ionising
indirectly and may travel right through the body. High LET radiations deposit a lot of
their energy per unit path length and tend to ionise directly causing greater damage but
travelling only a relatively short path through the tissue. The difference in the two
mechanisms of tissue damage lies in the speed of particulate radiations and the energy
of electromagnetic radiations.
For low LET radiation, the proportion of sublethal injury to cells contributes very
significantly to the overall injury. This proportion reduces with increasing LET.
Consequently, the amount of sublethal damage that can be repaired between fractional
exposures declines with increasing LET of the radiation. Furthermore, the relative
biological effectiveness (RBE) of radiation increases with increasing LET and
decreases with decreasing dose or dose fraction for a given LET.
Death of large numbers of cells within an organism, as in the case of severe exposure to
X or gamma rays, usually results in the death of the organism itself. The radiation will
kill fast growing cells such as the white blood cells and the person usually dies of
secondary infection within days.
Alpha radiation does not present a significant external radiation hazard, because it only
has a range of several centimetres in air and is stopped by the outer layers of human
skin. However, if taken inside the body alpha radiation presents the most serious
internal radiation hazard of all because of its propensity for intense ionisation in a local
area of tissue.
Nuclei that emit alpha particles are heavy nuclei. The chemical properties of such
elements dictate that they are bone seekers and that they have long biological half lives.
Consequently, many alpha emitters have been associated with bone cancer.
Beta radiation rarely presents a large external hazard unless it is highly energetic (e.g.
Phosphorous-32) and close to the skin, in which case it may cause injury to the outer
layers of skin. If taken within the body beta radiation represents a significant internal
hazard due to its ability to ionise the tissue in a localised area.
Gamma, X and neutron radiation are the most serious as external radiation hazards due
to their ability to traverse large distances. They may cause injury to all areas of the
body without much localisation. They do not represent the same internal radiation
threat as particulate radiations because most of the energy may pass through the body
without causing any damage.
33
5.2.3 The Relative Effects of Specific Radiations
The ICRP define radiation weighting factors (WR) to express the relative biological
effectiveness of different kinds of ionising radiation. These were formerly known as the
"Quality Factors". The radiation weighting factor is related to LET and RBE. The
ICRP recommend the radiation weighting factors given in Table 2.
Table 2: Radiation weighting factors for various types and energies of radiation
The ICRP define RBE as the inverse ratio of the absorbed doses producing the
same degree of a defined biological end-point. In simple terms this is an index
of the relative danger of different types of ionising radiation.
LET denotes the average energy imparted to tissue per unit length along the path
of travel of an entity of ionising radiation.
1
The reason for the decline in WR for highly energetic neutrons is due to their change in ability to ionise locally. i.e. Thermal
neutrons behave like alpha particles and fast neutrons behave like gamma particles.
34
5.3 Susceptibility to the Effects of Ionising Radiation
5.3.1 Tissue Susceptibility
Different tissues within the body show differing susceptibilities to the effects of
ionising radiation. The ICRP have summarised this information in terms of the
tissue weighting factors (WT) given in Table 3. The tissue weighting factor
represents the relative contribution of a particular organ or tissue to the total
detriment (see the definition of detriment in section 8) due to the effects of
uniform irradiation of the whole body. It is considered that those organs or
tissues with the highest WT values have the greatest susceptibility to ionising
radiation.
Fast growth rate is the underlying reason why cancerous cells, white blood cells
(bone marrow), the gonads and the foetus are the most susceptible to the adverse
effects of ionising radiation.
35
the young and the sick are the most susceptible to the deleterious effects of
exposure to ionising radiation.
For the purposes of quantifying the dose of ionising radiation on living tissues, it
is useful to consider the following diagram:
1
2
Source
organ 1 dose 1
organ 2 dose 2
organ 3 dose 3
A source of ionising radiation may emit radiation that varies in quantity with time and
space. This is called an EMISSION. The part of the emission that contacts the person
exposed to ionising radiation is the EXPOSURE. Exposure is defined only for X-Rays
and Gamma Rays with energies up to 3 MeV. The SI Unit is the Coulomb per Kilogram
(Ckg-1 ).
37
When a material is exposed to radiation, it will absorb radiation energy. The effect
depends on the Energy absorbed per unit mass of the material; this is the ABSORBED
DOSE (D). The SI Unit of Absorbed Dose is Joule per kilogram (Jkg-1 ), this is called
the Gray (G).
Absorbed Dose is used for all kinds of ionising radiation. The effect of ionising
radiation on a biological system depends not only on the Dose but also on the kind of
radiation and its energy. This difference in effect is taken account of by using the
Radiation Weighting Factor (WR). The values of the radiation weighting factor relate to
the radiation incident on the body, or for internal sources, emitted from the source, (see
table 2 for the values of radiation weighting factors). A good indication of the average
biological damage caused by radiation is the EQUIVALENT DOSE (HT). The unit of
Equivalent dose is given the name SIEVERT (Sv) and is Joule per kilogram (Jkg-1).
HT = WR . D (Sievert)
The Gray is determined solely by physical factors whereas the Sievert is combines both
physical and biological factors.
The dose calculated for the whole body is "EFFECTIVE DOSE" (E). Effective dose is
the sum of the weighted equivalent doses in all tissues and all organs of the body of a
single person (see table 3 for tissue weighting factors).
E = ΣWT . HT (Sievert)
38
• Equivalent Dose (HT) :Average biological damage caused by radiation.
Depends on radiation weighting factor: HT = WR X D.
Units: JOULE/ KILOGRAM . Called SIEVERT.
• Effective Dose (E): The tissue weighted equivalent dose for each tissue.
Depends on tissue weighting factor WT : E = WT X HT.
Units: JOULE/KILOGRAM. Also Called SIEVERT.
Can also have EFFECTIVE BODY DOSE: E = ∑ WT X HT
Absorbed dose rate for organ = 14A (Uav1 + Uav2 + .....) μGy/day.
M
Calculations are complicated because only a fraction of the gamma energy is deposited
within the body. This is the reason that gamma sources are generally less hazardous
than alpha or beta emitters when they get into the body.
39
5.4.2.2 External sources.
These calculations have already been done for many radionuclides. Values are available
in tables eg AS2243.4, Table A3 and are listed as gamma dose rates per Gbq at 1
metre.
40
6. THE BIOLOGICAL EFFECTS OF IONISING RADIATION ................................................... 42
41
6. THE BIOLOGICAL EFFECTS OF IONISING
RADIATION
Somatic effects are a result of personal exposure to ionising radiation and are a direct
manifestation of cell death, blocked or delayed cell division or mutation of genetic
material. Somatic effects may be further divided into "early" and "late" effects.
• Early effects: Early effects are those that occur immediately after to a few weeks
after an acute exposure to ionising radiation. An early effect may be permanent or
temporary. The effects are usually due to a major depletion in cell populations;
particularly in the more susceptible organs. All somatic early effects are considered
to be deterministic (See Section 6.1.2.2).
• Late effects: Late effects are those that arise either a long time after a single acute
exposure, or during the latter part of a course of chronic exposure. A late effect may
be permanent or temporary.
Hereditary effects appear in the first- and later-generation progeny of the exposed
individual, and are caused by alteration of the genetic material of the exposed
individual. Hereditary effects caused by exposure to ionising radiation are considered
to be stochastic (See Section 6.1.2.1).
42
6.1.2.2 Deterministic effects
An acute dose of approximately 1Gy may result in nausea, vomiting, rapid pulse and
fever, a few hours after the exposure. This is the direct result of damage to cells lining
the intestine. This is a somatic, early, deterministic effect.
6.2.1.2 Death
It is accepted that acute doses of ionising radiation above 2Gy have a reasonable
probability of early death for the individual irradiated. A dose of 3-10Gy results in the
victim suffering severe depletion of white blood cells and usually dying of secondary
infection within a few weeks. The lethal dose to 50% of a heterogeneous population, 60
days after dosing, is considered to be 3-5Gy.
Doses of 10-50Gy result in a survival time a few days in the majority of cases. The
cause of death is usually dehydration and massive bacterial invasion due to the damage
sustained by the intestinal lining. Survivors of doses in this range may face long-term
complications such as fibrosis, stricture, intestinal perforation and fistula formation.
Doses in excess of 50Gy result in death within a few hours due to damage to central
nervous system tissue. Death in this manner is a somatic, acute, deterministic effect.
6.2.1.3 Cancer
This may occur in almost any organ in the body and its initial location is dependent on
the type of radiation, the isotope and the area of the body that is exposed. The
mechanism of cancer induction is believed to be a direct result of the ionising potential
of radiation.
The probability of inducing cancer with a set low to medium dose of low LET radiation
is reduced as the dose is fractionated or protracted. Presumably, this is because a great
proportion of the damage is sublethal and the body can repair this prior to the next
43
irradiation. On the other hand, the probability of cancer with the same set dose of high
LET radiation stays constant or increases as the dose is protracted or fractionated. In
this case, there will be a lesser proportion of sublethal damage that can be repaired prior
to each irradiation of a given dose than with low LET radiation. (See also Section
5.2.1).
Radiation induced cancer is rarely distinguishable from cancers that are due to other
factors, except perhaps in the case of thyroid cancer where the individual is known to
have had a high exposure to iodine isotopes. The main examples of cancers that may be
induced by exposure to ionising radiation are shown in Table 5.
There is considerable debate in scientific circles about the threshold levels of radiation
dose required to cause cancer. The ICRP work on the assumption that the probability of
cancer increases linearly with dose. Currently, the assumption of no threshold for
radiation induced cancer has been adopted, thus making it a somatic, stochastic and late
effect.
The liver is the most sensitive to radiation. Its function is impaired if the whole organ is
exposed to a fractionated, therapeutic X ray dose of over 30Gy. Early hepatic injury
does not cause interruption of hepatocyte renewal, as this is very slow. A large dose to
most of the organ may kill a sufficient number of hepatocytes and cause liver failure (an
early, somatic, deterministic effect).
Lower doses may cause damage to the hepatocyte genetic material and render the cells
incapable of mitotic division. In this way, atrophy and cirrhosis may develop as the
liver slowly deteriorates. This is a late, somatic, deterministic effect.
44
6.2.2.2 The salivary glands
The salivary glands may undergo necrosis, atrophy and fibrosis after 50-70 Gy of
fractionated X rays. This is exhibited as an early or late, somatic, deterministic effect
resulting in reduced salivary output.
Beta radiation of all energies, and low energy gamma radiation may have deleterious
effects on the skin. The effects of high energy gamma and X rays will generally be
controlled by dose limits to other organs. Alpha radiation is simply not sufficiently
penetrating to damage skin.
6.2.3.1 Erythema
Ionising radiation will cause severe reddening of the skin reflected by dilation of the
capillaries after the release of histamine-like substances from injured epithelial cells.
The initial reddening may only last several hours but it may be followed 2-4 weeks later
by one or more waves of deeper and more prolonged erythema. The threshold for this
effect is 3-5 Gy as an acute dose.
The response to ionising radiation of different bodily tissues varies in the following
descending order of sensitivity: front of the neck, elbow and the backs of the knees;
front surfaces of extremities, chest and abdomen; face (not strongly pigmented); back
and top surfaces of extremities; face (strongly pigmented); nape of neck; scalp; and
palms and soles. Erythema is considered to be an early, somatic, deterministic effect.
6.2.3.2 Epilation
Temporary epilation (hair removal) may be induced by a single, acute dose of low LET
radiation of 3-5 Gy. Permanent epilation may result from a single, acute dose of 7 Gy
or 50-60 Gy fractionated over several weeks. Temporary and permanent epilation is an
early, somatic, deterministic effect of radiation exposure where the time frame over
which the injury is expressed is related to the kinetics of renewal of the epidermal cells.
45
6.2.3.3 Desquamation and necrosis
The threshold doses required to produce desquamation and necrosis of the epidermal
tissue are higher than for erythema, but not well established. The threshold doses
increase with fractionation and protraction of exposure. Desquamation and necrosis are
early, somatic, deterministic effects of exposure to ionising radiation whose time of
appearance is related to the kinetics of turnover of the epidermal cells.
Skin atrophy and fibrosis are late, somatic, deterministic effects that are not related
entirely to the kinetics of replacement of the epidermal cells. Instead, these changes
appear to be mainly related to the depletion of fibroblasts and injury to blood vessels in
the dermis. Estimates of the dose required to elicit responses of skin atrophy and
fibrosis are sketchy but the ICRP put forward an estimate of 10-30 Gy for low LET
radiation accumulated over a period of 8-25 years.
Basal cell and squamous cell carcinomas, but not melanoma (the most dangerous of all
skin cancers), have been associated with exposure to ionising radiation. The risk of skin
cancer is influenced by an individual's exposure to ultraviolet radiation and the degree
of pigmentation that their skin possesses. It is known that exposures to the skin in
excess of 10 Gy carry a significant excess risk of skin cancer. It is now thought that this
risk may be significant down to 1 Gy. Radiation induced skin cancer is a late, somatic,
stochastic effect.
The threshold of significant depression of the blood forming process for an acute dose,
given to the whole bone marrow, is 0.5 Gy. The dose rate threshold for protracted
exposure over many years is more than 0.4 Gy per year. The various cells of the
haematopoietic system are depleted at different rates. The white blood cells are one of
the most sensitive and reach their lowest concentration in the blood after 5 weeks. This
effect of depletion is an early, somatic, deterministic effect.
There is a high probability of death if the dose is acute and over 2 Gy and no treatment
is given (see section 6.2.1.2).
All sensory organs except the lens of the eye are relatively resistant to the effects of
ionising radiation. The middle and inner ear are known to be able to withstand up to 50
Gy of highly fractionated irradiation without any serious effects on hearing. The lens of
the eye is prone to developing cataracts after irradiation. Neutrons have been shown to
have the greatest RBE in this regard. Cataracts are regarded as a late, somatic,
deterministic effect.
The radiation causes breakdown of the dividing cells in the anterior epithelium of the
lens. The waste products of this damage collect on the lens of the eye to form the
cataract. In the early stages, radiation induced cataracts are distinguishable from
cataracts of other origins. Studies indicate that vision-impairing cataracts may be
induced by X rays from a dose of 2 Gy as a single, acute exposure or a dose of 8 Gy as
an exposure fractionated over months or years. The doses of neutrons required to affect
the same changes are considered to be less; 0.5-1 Gy for an acute exposure and 3-5 Gy
for an equivalent fractionated exposure. The general threshold that is given to avoid
visual impairment in the case of occupational exposures that are highly fractionated and
protracted is a maximum of 0.15 Sv per year.
The nervous system is regarded as relatively radioresistant. All effects to the nervous
system are late, somatic and deterministic. Functional impairment has been observed in
the brain after its irradiation with acute doses above 10 Gy. Necrosis of the brain was
not fully apparent until several years after exposures above a threshold of 55 Gy
delivered over 5.5 weeks to the whole brain.
Damage to the spinal chord consists of demyelisation and necrosis of the white matter
and develops slowly after exposure. The threshold for this type of damage appears to
be 30 Gy if the dose is fractionated into 3 Gy increments or 40-50 Gy if the increments
are 2 Gy each. The peripheral nerves may be damaged at doses in excess of 60 Gy
delivered as conventionally fractionated radiotherapy.
The germ cells of both sexes are more highly radiosensitive than other reproductive
cells. All effects of sterility on the germ cells are early, somatic and deterministic.
In the testes, spermatogonia are more sensitive than the spermatocytes, spermatids and
spermatozoa. Temporary sterility due to a reduced sperm count may be caused by an
acute exposure of 0.15 Sv. The count will not increase for several weeks until the
spermatogonia are at the maturation stage. An acute dose of 3.5-6 Sv may cause
47
permanent male sterility as the stem cells may be damaged and take years to regenerate.
If the dose is highly fractionated or protracted over a period of many years, the
threshold for temporary sterility is 0.4 Sv per year, and for permanent sterility it is 2.0
Sv per year.
In the female ovary, the mature oocyte is the most radiosensitive. An acute exposure to
both ovaries of 2.5-6 Sv may cause prompt, permanent sterility, as the oocyte is not
replaced in the female reproductive cycle. Older women are more sensitive due to their
depleted stocks of oocytes. The corresponding threshold for a highly fractionated or
protracted exposure over many years is 0.2 Sv per year with an upper dose limit of 6 Sv.
The dose required for significant injury to the organs of the urinary tract is lowest for
the kidneys, intermediate for the bladder and highest for the ureters. All the effects are
late, somatic and deterministic.
The damage to the kidney appears to involve degeneration of the nephrons and the
vasculature leading to degeneration of the renal tubules. This develops over 6-12
months as a result of radiotherapy doses exceeding 10 Gy. At higher doses the damage
may be permanent. The tolerance of the bladder is approximately 55-60 Gy fractionated
over 4 weeks. Complications of larger doses include; cystitis, ulceration, fibrosis,
constriction and urinary obstruction.
The alveoli and pulmonary vasculature within the lungs are the most sensitive of the
respiratory system. A single acute dose above 10 Gy or 20-30 Gy fractionated over 6-8
weeks may cause a fatal pneumonitis within 2-6 months. Those surviving the early
symptoms may later succumb to pulmonary fibrosis. The nasopharynx, pharynx,
larynx, trachea and bronchi require doses of at least 30 Gy fractionated into 2 Gy lots to
effect conditions such as ulceration, atrophy and fibrosis.
Mature muscle, bone and cartilage are relatively inert to ionising radiation. All effects
on the musculoskeletal system are late, somatic and deterministic. Mature cartilage will
tolerate 40 Gy fractionated over 4 weeks or more than 70 Gy fractionated over 10-12
weeks. Mature bone will tolerate 65 Gy fractioned over 6-8 weeks and muscle will
tolerate 60 gray in 2 Gy fractions. At doses in excess of these, contraction and delayed
healing of muscle may occur and other tissue may have reduced tolerance to subsequent
trauma.
Fractured bones that are healing and the musculoskeletal system of children is more
susceptible to the effects of ionising radiation. At doses of 1 Gy these tissues may show some
retardation of growth. A conventionally fractionated, therapeutic dose of 20 Gy may cause
scoliosis, kyphosis or other skeletal disorders.
48
6.2.12 The Endocrine System
The most sensitive of the endocrine glands is the thyroid, particularly in children.
Functional thyroid damage ensues when the whole of the organ is exposed to doses in
excess of 25-30 Gy fractionated over 30 days. In children hypothyroidism and retarded
growth have been observed at lower radiation doses. For permanent functional
depression of the adult pituitary and adrenal gland the threshold doses are 45 and 65 Gy
respectively, of fractionated irradiation.
The effects of ionising radiation on the unborn child depend almost entirely on the stage
of development. Up to 3 weeks after conception, the number of cells is small and they
are not yet specialised. A small, acute radiation exposure (such as 0.1 Gy) may be an
undetectable death and purging of the embryo. Higher doses during later stages of the
pregnancy may produce the same effect.
During the third week, the period of organogenesis begins with the formation of the
nervous system and heart. From this time until the end of major organogenesis at start
of the ninth week after conception, the embryo is vulnerable to malformations in any
organ under development at the time of exposure. Such malformations are late,
somatic, deterministic effects and are estimated to have a threshold of 0.1 Gy in human
beings. Growth disturbances may be the predominant effect during the latter stages of
pregnancy, although the thresholds for these are not well known.
Throughout the period commencing 3 weeks after conception and ending at birth, the
unborn child may be susceptible to an increased probability of cancers or leukaemias,
expressed in the first decade of life. Estimates of the doses required to increase this
probability are unavailable at this time. This form of cancer is a late, somatic,
stochastic effect.
During this same period, the brain of the unborn child appears to be particularly
vulnerable. Data from Hiroshima and Nagasaki indicates that IQ may be affected (a
direct relationship with increasing dose). A coefficient of 30 IQ points may be lost per
Sv of exposure by the unborn child in the period from 8 to 15 weeks after conception.
During this period, the excess probability of severe mental retardation is calculated at
0.4 per 1 Sv of exposure in utero. The brain appears to be less susceptible during the
period of 16-25 weeks; the excess probability is reduced to 0.1 per Sv of exposure.
After 25 weeks, the probability of severe mental retardation appears to be within the
normal statistical range. Effects on the brain are regarded as late, somatic and
deterministic.
49
6.4 The Effects of Ionising Radiation on Later Generations
Nearly all disease is to some extent genetic and to some extent environmental. At the
genetic end of the spectrum are conditions that relate almost entirely to chromosomal
anomalies or gene mutations (Mendelian conditions). These tend to be rare. In the
middle of the spectrum are conditions that are more common and tend to cluster in
families. These are known as "partially genetic" or "multifactorial". At the
environmental end of the spectrum is infectious disease. Mendelian, chromosomal and
partially genetic disorders are the subject of the remainder of this section.
Mendelian conditions are subdivided into four groups, listed in Table 6. It should be
noted that "dominant" conditions usually occur in the first generation progeny of the
irradiated person. "Recessive" conditions may occur in later generations if inherited
from both parents. "X-linked" refers to a mutated gene on an X (female) chromosome.
Mendelian disorders
Condition Examples
Autosomal dominants Appear in adult life:
Huntington’s disease, polycystic kidney
disease, multiple polyposis, cerebellar
ataxia and myotonomic dystrophy
50
Multifactorial disorders
Condition Examples
51
7. SOURCES OF EXPOSURE TO IONISING RADIATION ......................................................... 53
52
7. SOURCES OF EXPOSURE TO IONISING
RADIATION
All irradiating apparatus poses an external hazard to any subject being irradiated. They are
usually in the form of an X ray machine.
These are the most commonly used irradiating apparatus. They are in wide use at Monash
University for many of the following applications:
• Diagnostic radiology: Low and medium energy X rays are used for imaging parts of the
body for medical, teaching research and veterinary purposes. Diagnostic radiology
procedures are performed by Monash University staff in many departments. Diagnostic
radiology is considered to represent the largest single source of radiation exposure for most
members of the Australian public.
Persons who are subjected to diagnostic radiology may receive doses of ionising radiation in
the orders of magnitude shown in Figure 19 (on the following page).
• Therapeutic radiology (radiotherapy): Higher energy X rays may be used for the medical
treatment of certain conditions such as cancer. At Monash University therapeutic radiology
finds application as part of research using humans or animals as subjects. Such experiments
are carefully controlled and examined by the Department of Human Services and the RPO
prior to their beginning. Persons receiving radiotherapy treatment to kill malignant tumours
may receive doses in the order of tens of gray to a localised area from a cobalt-60 gamma or
X ray source.
• Industrial radiography: High energy X rays are used in industrial radiography for
examining artefacts such as coins. Invariably exposure from these sources of ionising
radiation will vary in magnitude and will be due to accidents.
53
Means of Exposure
Size of a single dose
Exposure from current chromium-51 (g) from stores in the blood 400 μSv
Exposure from current cobalt-58 (g)from Vitamin B12 absorption 300 μSv
Figure 19: Approximate sizes of radiation doses for various medical procedures
54
7.1.1.2 X ray fluorescence and diffraction analysis
These types of instruments are generally used for research for examining crystal structure. They
produce high energy X rays and can be used in alloy analysis, chemical plating analysis as well
as general chemical analysis. The technique depends on the unique characteristics of emission
of a particular element when impinged on by an X ray beam.
Examples are electron microscopes, cathode ray tubes, high voltage electronic rectifiers and
television screens, which all produce small amounts of low energy X radiation. These are
generally considered to constitute a minor external radiation hazard. One example of the
magnitude of such exposure is that of watching three hours of colour television per day at a
normal distance. This gives an exposure of approximately 5 mSv per year.
A sealed source by definition is any radioactive material that is firmly contained so as to prevent
dispersion under normal conditions of handling or storage. Sealed sources usually constitute an
external radiation hazard. A leaking sealed source can pose an internal radiation hazard if
contamination is spread. Some examples of the sources held by Monash University, their
activities and their uses are listed in Table 8.
55
7.1.3 Sealed Source Apparatus
Sealed source apparatus contains one or more sealed radioactive sources installed in a housing
that prevents or minimises exposure of the users to the source. They usually constitute a minor
external radiation hazard when the housing of the source is in good condition. It is violation of
this housing during maintenance or transport that generally leads to exposures. Examples of
sealed source apparatus used at Monash University are the radium-226 sources commonly
found in beta counters and the nickel-63 sources used within the electron capture detectors of
gas chromatographs. Some of these sources are listed in Table 9.
Unsealed sources are not contained in the same manner as a sealed source. They will readily
produce contamination if handled inexpertly. Unsealed radioactive material can be a major
external and internal radiation hazard. A wide variety of unsealed radioactive nuclides are used
for research at the various sites of Monash University. Some of these are listed in Table 10.
The radiation dose Australians receive due to radioactive fallout is approximately 3 μSv/yr.
This may be directly attributed to mankind's activities with radioactive materials such as; atomic
56
bomb use and testing, accidents in nuclear power plants and incorrect disposal of nuclear
material which may become airborne. Some of the major radioisotopes involved are plutonium-
239, carbon-14, strontium-90 and caesium-137.
Cosmic radiation comes from the sun and its intensity varies with altitude. Table 11 gives
estimates of radiation exposures due to cosmic rays for people situated at various altitudes:
Primary cosmic radiation also interacts with other atmospheric materials to produce secondary
cosmic radiation in the form of radionuclides such as tritium, beryllium-7, carbon-14 and
sodium-22.
Exposure from terrestrial radiation comes mainly from the ground and building materials.
Radioisotopes such as potassium-40, uranium-23 and thorium-232 have half-lives in the order
of 109 years and thus emit radiation for a long time. They are common constituents of soils and
building materials.
All people are exposed to various forms of natural radiation. Exposures can vary from 200 -
25,000 μSv per annum, depending on the soil and rock composition. In most parts of Australia,
radiation from terrestrial sources is estimated to be 500 μSv per annum. In comparison, in some
parts of India an exposure rate of 25,000 μSv per annum has been documented; this has been
attributed to the high thorium content of the soil.
57
houses specifically built for colder climates (eg USA). Some examples of typical exposures to
terrestrial sources of radiation are given in Table 12.
Source Exposure
Living in a brick or concrete house 1000 μSv per year
Consuming an average quantity of water, 250 μSv per year
food and air
The average natural radiation exposure (cosmic plus terrestrial) for an Australian is about
2000μSv or 10% of the current occupational whole body dose limit. There are other sources of
non-occupational exposure to radiation.
The natural, terrestrial, medical, fallout and miscellaneous sources of radiation exposure all add
up to give the average Australian who does not work with ionising radiation an exposure of
approximately 2700 μSv per annum.
58
8. THE LEVEL OF RISK IN RELATION TO THE USE OF IONISING RADIATION ............. 60
59
8. THE LEVEL OF RISK IN RELATION TO THE
USE OF IONISING RADIATION
The ICRP have defined "risk" as a concept that includes probability of death and
contributions from other factors such as illness, hereditary disease, risks to the foetus,
economic losses, anxiety and other societal impacts. The probability of death aspect of
risk is far more quantifiable than the other factors. As a consequence the ICRP only
quantifies, in terms of numerical probabilities, the magnitude of risk that some of the
factors other than death, present.
The ICRP have not numerically defined an acceptable level of risk in their latest
publication (ICRP 60) due to the immense social difficulties in doing so. Previous dose
limits (ICRP 26) were based on an annual occupational death probability of 10-3 as
being just acceptable. This is no longer considered to be the case.
The ICRP defines a quantity known as the "total detriment". Total detriment is the
mathematical expectation of total harm that would eventually be experienced by an
exposed group and its descendants as a result of the group's exposure to ionising
radiation. Total detriment is a function of the probability and severity of effects. Total
detriment is made up of "health detriment" (effects on health) and "other detriment"
such as the need to restrict the use of some geographical areas or products. In giving
mathematical probabilities for radiation induced effects the ICRP has considered only
health detriment.
The health detriment can be subdivided into four different components; fatal cancer in
any organ, loss of a segment of life due to fatal cancer, morbidity resulting from
induced non-fatal cancers and the risk of serious hereditary disease in later generations.
60
8.3 Probabilities of Deleterious Effects
The incidence of mental effects for low LET radiation exposure to the unborn child are
listed below in table 13. The incidence of hereditary effects due to low LET radiation
exposure are listed in table 14. Both of these tables provide the data as effects per million
people per mSv of exposure
Table 14: Incidence of severe hereditary effects due to low LET radiation
61
8.3.1.2 High LET radiation
The probabilities would be the same as those for low LET radiation except that the dose
required to elicit the same response will be higher in line with the value of WR. For
example, a 1 mSv dose of alpha radiation at the tissue would be expected to have the
same probability of a certain (defined) deleterious effect as a 4 mSv dose of beta,
gamma or X rays.
Note that the increased chance of fatal cancer for a member of the public over a
radiation worker is indicative of the good health of people in the working population
versus those in the general population.
In order to compare the annual detriment between a radiation worker population and a
non-radiation worker population the variables chosen for the radiation worker
population were as follows (ICRP 45):
The total detriment for the radiation worker population was equal to that for a non-
radiation worker population that had a fatal accident rate of 35 - 50 x 10-6 per year. In
other workers the 2 mSv of occupational exposure to ionising radiation encountered by
radiation workers had added between 10 and 25 fatalities per million radiation workers
at risk. This fatality rate is still less than many non-radiation industries:
62
8.4 Levels of Ionising Radiation Exposure
Table15: Whole Body Exposure to Alpha, Beta, Gamma and X Rays (Data from
ARL on occupational radiation exposures in Australia
Table 16: Extremity Exposure to Alpha, Beta, Gamma and X Rays (Data from
ARL on occupational radiation exposures in Australia)
63
9. STATUTORY REQUIREMENTS.................................................................................................. 65
64
9. STATUTORY REQUIREMENTS
In Australia, responsibility for ionising radiation safety lies with the state and territory
governments who have enacted law to control the use of ionising radiation sources. The
recommendations of the NH&MRC have been adopted by the state and territory
governments in most cases.
Monash University follows the directives of the Victorian State Government in relation
to ionising radiation. The Department of Health and Community Services, Victoria is
the administering body for the Health (Radiation Safety) Regulations 1994. A large,
but not exhaustive list of statutory documentation connected with ionising radiation
including; Australian Standards, codes of practice and guidelines is to be found in
Appendix B.
• Division 2AA of the Health Act which invokes the radiation safety regulations.
• The Occupational Health and Safety Act 1985. This Act forces a duty of care
upon all employers and a duty of responsibility on all employees. It requires an
employer to provide and maintain so far as is practicable, for employees, a
working environment that is safe and without risks to health. An employee is
required to take reasonable care in performance of duties and is prohibited from
any wilful or reckless actions that may place themselves or other persons at risk.
Australian Standards, codes of practice and other guidelines produced by expert bodies such as
the NH&MRC and Worksafe are all examples recommendations that are not legally binding in
their own right although some are adopted under the Health (Radiation Safety) Regulations
1994.
65
The recommendations within Australian Standards, codes of practice and other
guidelines are often used very effectively as evidence in the courts to prove negligence
in a common law claim or non-compliance with the Health (Radiation Safety)
Regulations 1994.
9.3.1 Licences
9.3.1.1 General
Monash University rules for licensing are discussed in Section 16 of the Policy
Statement.
Any person carrying out work involving ionising radiation must be licensed to do so or
must be working under the direction and supervision of a person holding such a license
(in Monash's case the RPO). Persons who are employed or undertake courses of study
at Monash may function under the umbrella coverage of licences held by the
University’s various sites.
Dedicated operator licences are required for individual persons who are practising
radiologists, diagnostic medical radiographers, radiation oncologists, medical therapy
radiographers, nuclear medicine specialists, nuclear medicine technologists, general
medical practitioners, dentists, chiropractors, dermatologists, ophthalmologists, other
medical specialists, paramedics (for the purposes of undertaking limited radiographic
procedures), persons who test radiation safety of ionising radiation apparatus and sealed
radio-active sources, servicemen of ionising radiation apparatus, principal researchers
of medical or scientific research involving the administration radiation to humans,
veterinary surgeons and industrial radiographers.
Monash University currently holds a site licence for Clayton Campus to carry out
research involving the irradiation of human volunteers. However, project approval as
well as operators licences are necessary before any work can commence. Operator
licences are paid for by the department directly involved in carrying out the research.
66
9.3.1.3 Licensing by type of ionising radiation source
These are now required to be held as separate site licences. The conditions of
the licences are set out on the certificates of registration and may be obtained on
request from the RPO or the DRPO.
Monash University Site licences are administered through OHSE and the fees
are paid from central funds. The University is required to specify the types of
sources and quantities of radiation that are to be held under each licence
category. The conditions of each licence are only valid for as long as this
information is correct. Consequently, it is imperative that people who are
increasing their stocks or types of unsealed sources, provide OHSE with
complete details prior to their purchase, so that the licences may be kept up to
date as required by the regulatory authority.
67
Sealed source apparatus and sealed sources:
Irradiating apparatus:
9.3.2 Registrations
Monash University rules for registration are discussed in section 16 of the Policy
Statement.
Individual ionising radiation sources of any of the following types must be registered.
• Irradiating apparatus.
• Sealed source apparatus.
• Sealed sources.
The RPO must be notified of any change of location of any X-Ray machine or
irradiating apparatus prior to relocation and after the equipment has been installed in its
new location so that safety checks can be performed. The Department of Health and
Community Services must be promptly notified of any change of ownership or location.
The owner of any registered source of ionising radiation is required to keep the most
current registration label affixed to the source at all times. In the case where this is
impossible, the registration must be kept by the departmental RSO or deputy RSO.
The Department of Health and Community Services, Victoria has placed conditions on
all registrable sources of ionising radiation. These conditions are set out on the
certificate of registration for that particular source and must be complied with at all
times.
Radiation safety testing is required for any registrable source of ionising radiation to
demonstrate compliance with conditions set out on the registration, and as stated in
68
Section 5 of Health (Radiation Safety) Regulations 1994. Testing is usually carried out
when the source is first registered and again after two years of initial registration.
9.3.4 Exemptions
The Health Department of Victoria has the power to exempt and to apply conditions of
exemption of any irradiating apparatus, sealed source apparatus or other radioactive
substance that it considers is without significant radiation hazard. A list of exemptions
may be found under Part 6 Health (Radiation Safety) Regulations 1994.
These apply to the person/s responsible for any particular registered ionising radiation
source or the licensee/s in possession of unsealed radioactive sources. This person must:
• Provide to all employees and authorised visitors who may be exposed to ionising
radiation from the source with safety instructions and equipment as necessary.
• Ensure that the radioactive substance does not leave its controlled area under
circumstances that may permit exposures in excess of the current dose limits.
• Ensure the area where persons who are not radiation workers but who habitually
occupy an area near the ionising radiation source, cannot be exposed to levels of
ionising radiation above one tenth of the dose limits for radiation workers. (Note
that this figure is now one twentieth with the most recent dose limits).
• Ensure that the radioactive source is not used, sold, stored, transported or
disposed of in circumstances where a person may be exposed to ionising
radiation in excess of the appropriate dose limit.
• Notify the Health Department of Victoria (via the RPO) of a lost, damaged or
relocated source of ionising radiation.
• Notify the RPO or Deputy RPO of any relocation of any sealed source of
ionising radiation prior to relocation.
69
• Do not deal with a radioactive substance in such a way as to cause a radiation
worker to be exposed to airborne radioactive material in an average annual
concentration in excess of those in Table A3 of Australian Standard Safety in
laboratories, Part 4: Ionising radiations (AS2243.4 (Int)) 1994.
This is applicable to the use of ionising radiation apparatus or radioactive substances for
medical diagnosis.
These are set out in Schedule 1, Health (Radiation Safety) Regulations 1994. The limits
are set out in detail in Section 13 of this manual.
This is detailed under Part 9 of Health (Radiation Safety) Regulations 1994. Personal
monitoring is required for any person who is likely to be exposed to ionising radiation
as a result of their work. The licensee or owner of a registered source of ionising
radiation is responsible for instituting a personal monitoring program, at Monash
University this is the RPO, department heads , RSOs and deputy RSOs.
The Department of Health and Community Services, Victoria has the power to specify
the period that monitors must be worn. They can order that a radiation worker undergo
biological monitoring and specify the intervals at which biological monitoring must be
carried out. To date the Health Department has not made any special demands of the
University.
The Health Department requires notification in writing within 24 hours of any exposure
or suspected exposure exceeding 5 mSv in a single week. This notification is carried
out by the RPO. Any suspected exposures should be immediately reported to the RSO
or DRSO who should then take appropriate action.
70
Records of all personal monitoring, including annual exposures, are kept on the OHSE
database and are available on request.
The Health Department may direct that a medical examination to be carried out on any
person likely to be exposed to ionising radiation during impending, current or previous
employment. The cost of the examination shall be borne by the licensee or registered
owner of the ionising radiation source.
The licensee or registered owner of a source of ionising radiation shall not release
wastes in a manner that will cause persons to receive more than the annual dose limits
described in section 13 of this manual.
Radioactive material discharged into the sewerage system must be readily soluble and
miscible with water, it is subject to conditions relating to the allowable limit of intake
(ALI, see section 13 of this manual) for each radionuclide. Limits are set out in Section
73, Part 12 of the Health (Radiation Safety) Regulations 1994.
71
9.3.13 Penalties
9.3.14 Enforcement
A specially authorised officer may at any time, enter a place where it is known or
suspected that ionising radiation sources are kept and test, seize or render incapable of
operation any ionising radiation source or demand to inspect all related documentation.
72
10. EXPOSURE TO IONISING RADIATION .................................................................................. 74
10.1.2.1 Inhalation 74
10.1.2.2 Ingestion 75
10.1.2.3 Absorption 75
73
10. EXPOSURE TO IONISING RADIATION
10.1.1 Introduction
Internal exposure to ionising radiation is the irradiation of inner body tissues resulting from surface
or airborne contamination that has entered the body.
α increasing
β ⇑ internal
γ hazard
neutrons
It is the inadvertent release of unsealed sources (contamination) that poses the main threat as an
internal radiation hazard. Such contamination may easily become incorporated in organs or tissues
if it is not carefully controlled.
The extent and severity of an internal radiation hazard is related to the ionising capability of
specific radiation types.
10.1.2.1 Inhalation
Unsealed radioactive material may exist as a gas, vapour or aerosol if it is in the airborne form. The
fate of airborne radioactive material once inside the respiratory system depends on the size of its
particles and their solubility in the lung fluid. Examples of airborne radioactive contaminants are
iodine vapour or centrifuge aerosols.
74
The ICRP proffer the following as the likely fate of inhaled radioactive material:
• 50% is deposited in the upper respiratory tract (all areas of the respiratory tract except the
lung) and is subsequently cleared to the throat and swallowed.
• deposits in the lung and is either cleared and swallowed or taken directly into the
bloodstream
10.1.2.2 Ingestion
Unsealed radioactive material that exists as solid or liquid contamination on a work surface is the
most common form of ingested radioactive material. This is usually a result of poor housekeeping,
a lack of personal hygiene or allowing consumption of food in radioisotope areas. Ingested
materials pass through the gastrointestinal tract with absorption and excretion being determined by
solubility. Water soluble material will gain entry to the bloodstream and be readily passed to body
organs. Insoluble material will pass through the gut and be excreted.
For example, iodine will go to the thyroid and plutonium or phosphorous will be deposited in the
bone.
10.1.2.3 Absorption
Unsealed sources in a highly fat soluble, liquid form (e.g. organic solvents) are most commonly
absorbed through the skin or mucous membranes. Usually this is the result of spills or splashes
directly onto the skin or mucous membranes or material passing through an unsuitable glove. Solid
or airborne liquid forms of unsealed, highly lipid soluble, radioactive material may be absorbed
through the skin or mucous membranes. An example of this is isotope dissolved in ethanol.
When radioactive material is taken into the body, there is an initial rapid rise in the dose rate to the
internal organs and tissues. This initial rapid rise is followed by exponential decay.
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Time
Figure 20: The kinetics of isotope clearance
The biological half-life (Tb) is a measure of the time taken for half of the radioactive material
absorbed to be excreted from the body.
In reality however the effective half-life (Teff) of radionuclides being excreted from the body is
related to the radiological (T½) and biological half-lives by:
External exposure to ionising radiation arises from sources outside the body. Sealed and unsealed
sources and irradiating apparatus may all become external radiation hazards if handled incorrectly.
α increasing
β ⇓ external
γ hazard
neutrons
The extent of severity of an external radiation hazard is related to increasing penetrating power of
the radiation. In practice, alpha radiation is not regarded as an external hazard, due to its low
penetrating power.
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10.3 The Summation of Internal and External Exposure
In assessing overall exposure to ionising radiation, the total internal and external doses must be
summed as follows:
Total Exposure =
Hw + ∑ Ii
Hwb , L i Ii , L
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11. MONITORING FOR IONISING RADIATION ......................................................................... 79
78
11. MONITORING FOR IONISING RADIATION
11.1 Introduction
• Personal monitoring (monitor worn on the person) for the purposes of assessing
the equivalent dose to the whole body or extremities.
External dosimetry may be performed for the whole body or for parts of the body.
The whole body dose can be assessed by a single personal dosimeter only if the
wearer is in a uniform radiation field. The whole body external exposure is
measured using a thermoluminescent dosimeter which is worn by the individual
on the waist, as the gonads are the most radiosensitive organ. Users of neutron
moisture meters should wear personal, neutron radiation monitors.
A personal dosimeter should be supplemented with direct reading dosimeters
(e.g. Quartz Fibre dosimeter or a digital alarm dosimeter), when there is the
potential for high doses over a short period (usually minutes or hours).
The normal period for wearing a whole body TLD is 8-12 weeks, except for
pregnant women (4 weeks). All persons working with ionising radiation (i.e.
radiation workers), at the University shall be provided with and will be required
to wear personal monitoring devices.
Each personal dosimeter should be numbered, used by one person only and
returned promptly at the end of the issue period. In the event of a suspected
79
high dose, arrangements should be made with the relevant personal dosimetry
service for the particular dosimeter(s) to be processed and assessed as quickly as
possible. This is the responsibility of the RSO or deputy RSO.
11.2.1.2 Internal
• Personal contamination
Immediately after any procedures that use sources of sealed or unsealed ionising
radiation, the hands and laboratory coat should be examined with a count rate
meter. Such contamination is the most frequent source of internal exposure via
ingestion or absorption.
• Thyroid monitoring
Monash University requires that all persons who use radioactive iodine undergo
regular thyroid monitoring. Radioactive iodine concentrates in the thyroid and
persons routinely involved in handling radioiodine should have their thyroid
gland monitored at six monthly intervals. If radioactive iodine is being used
regularly, monitoring must be performed monthly, and immediately following
any major task using the isotope. In the case of persons infrequently using
radioiodine, thyroid monitoring should be carried out after each radioiodine
manipulation.
The thyroid monitor utilises a crystal of sodium iodide as the detector. This is
placed near to the throat and the result obtained after 2 minutes of counting (in
Becquerel) is compared with the ALI (see section 13).
80
• Whole body monitoring
Gamma and X emitting radionuclides and beta emitting radionuclides that have
sufficient energy to produce bremsstrahlung when distributed in the lungs or
throughout the whole body, can be monitored with whole body counters. Whole
body counters are ineffective for beta emitters except for those producing
bremsstrahlung. The difficulty lies in monitoring radiation that is distributed in
a non-uniform manner.
A large shielded room (to reduce background) with a flat bed or tilted chair (at
45 degrees) and a large sodium iodide detector are required. The detector is
placed over the abdomen. Sensitivity depends on the individual radionuclide.
Results are expressed in ALIs (see section 13).
• Bioassay
Urine, faeces, blood and sweat may be counted routinely or after (within several
hours) of a suspected or known exposure for a measure of internal radiation
exposure to certain radionuclides. Urine monitoring for tritium and carbon-14
beta emitters is the only bioassay monitoring commonly performed at Monash
University. Measurements taken long after exposure has occurred may not be
representative of a peak exposure e.g. Tritium may be measured in urine by
liquid scintillation counting, (sensitivity ≅370 Bq L-1 ).
The urine of persons working with unsealed sources of ionising radiation should
be performed regularly, provided the technique is thought to be reliable. A list
of the results should be retained to enable comparisons with the ALI for
inhalation (see section 13). Thus, any count that has increased significantly
since the last measurement can then be investigated.
11.2.2 Area
Radiation dose levels can be monitored with a dose rate meter. This is a method
commonly used for identifying any “hot spots”.
Extensive monitoring should be carried out during and immediately after the installation
and testing of new apparatus or after changes in experimental protocols and techniques.
Once the pattern of radiation from X ray producing apparatus has been established,
subsequent surveys may be less detailed.
Particular problems arise with narrow beam X ray apparatus (e.g. X ray
diffractometers), because the primary beam or sheets of scattered radiation are generally
very small in cross-section. A small volume, sensitive detector should be used.
81
Photographic methods may also be useful to detect the extent of the beam. Monitoring
of such apparatus should be performed with great care whenever experimental
conditions have been changed in any way.
Electron microscopy and diffraction (as distinct from X-ray diffraction) apparatus
presents fewer problems. A thorough initial survey when the equipment is installed is
usually sufficient. However, additional shielding can be added if necessary, in places
where the dose rate is high.
Surveys should be frequent where sealed or unsealed radioactive materials are used,
because the materials can be moved causing changes in the radiation pattern.
Because both alpha particles and low-energy beta particles have very limited
ranges in air, the detector must be held very close to, but not actually touching,
the surface under investigation.
If inferences are to be made about dose using a count rate meter, then the meter
must be calibrated in such a way that count rate can be related quantitatively to
dose rate.
Performing a wipe test: Use a filter paper or tissue to wipe an area for
contamination. The wipe should be moistened with deionised water or an
appropriate solvent. When a surface is wiped, only a percentage of the
removable contamination will be collected. Factors affecting the collection or
wipe efficiency include:
82
The pressure exerted when taking the smear.
The measurement of the area smeared.
The condition of surface tested.
The solvent used.
An area of at least 0.5-1m2 should be wiped. The smear samples must then be
counted in an area of known low background. Counting may be performed
using a scintillation counting instrument or a hand held meter. The choice of
instrument will be dependant upon the type of isotope present as contamination.
If you do not have a suitable source for calibration then as a worst case
assumption use Ec = 10%.
Detection Limit: The detection limit of the instrument can be determined once
the counting instrument’s efficiency has been determined. It is important that
the detection limit of the counting instrument be one DWL or lower. The
equation below can be used to calculate the detection limit of the instrument in
DWL’s.
The detection limit per DWL must be above background, preferably twice
background to ensure that contamination above the DWL can be detected.
83
equation below. This contamination level may then be directly compared with
the appropriate DWL.
All monitoring instruments shall be calibrated when first taken into use and at annual
intervals thereafter and following major repairs or service. Records of the date and
results of all calibrations shall be kept for two years after disposal of the instrument.
Calibration must be carried out at a laboratory equipped with calibration facilities. e.g.
The Australian Radiation Laboratories, Australian Nuclear Science and Technology
Organisation (ANSTO) or the Health Department of Victoria.
The RPO will advise departments of the due dates for calibrations. Departments will be
responsible for ensuring instruments are calibrated, paying for the calibration and
advising the RPO of the outcome.
Between annual calibrations, the RSO or deputy RSO should carry out constancy
checks. Where possible these should be made with the same type of radiation for which
the instrument is designed. The procedure for a constancy check is to place a source of
known count rate (this is not the same as activity) or dose rate (whichever is appropriate
to the instrument) for a specified distance, at that distance from the detector. The
subsequent readout on the instrument should be recorded for comparison with past and
future constancy checks. Any reading that deviates more than 10% from previous ones
or any trend in changing response necessitates a complete service of the instrument.
This should be done through the manufacturer, if possible, to avoid negating any
warranties on the equipment.
No detector can be calibrated or performance checked using one type of radiation and
reliably used to quantify other types of radiation. Be aware that some instruments have
multiple detectors for working over large ranges. Calibration and performance
checking must consider all of these as independent detectors.
84
11.4 Types of Instruments for Measuring Ionising Radiation
11.4.1 Count rate meters
These give a readout in counts per unit time in proportion to the number of ionisation
events that occur within their detector. Note that count rate is not the same as activity.
They are usually instantaneous readout instruments.
Common types of detectors used as count rate meters include; Geiger-Muller, ion
chamber, proportional and scintillation detectors.
These give a readout in dose units (Sievert or Gray) per unit time. They work on the
same basic mechanisms as count rate meters except that they sometimes include
provision for distinguishing between different types of radiation. e.g. A sliding plastic
plate across the detector to distinguish between alpha and beta radiation. They are
instantaneous readout instruments.
Common types of detectors used as dose rate meters include; Geiger-Muller, ion
chamber, proportional and scintillation detectors.
11.4.3 Dosimeters
A readout may be obtained some time after measurement or it may be a direct read out
instrument. The dosimeter is worn by the person to whom it is assigned for the
purposes of dose measurement over a reasonable period of time. A dosimeter should be
worn on the part of the body exposed to the highest dose rate of ionising radiation.
Dosimeters are a whole body or extremity monitor.
Types of detectors used as dosimeters; ion chamber QFD (quartz fibre dosimeter),
Geiger-Muller, DAD (digital audio dosimeter), film badges and TLD
(thermoluminescent detectors).
No single ionising radiation detector is universally applicable to all types and quantities
of ionising radiation. The following factors should be taken into account when
choosing a monitor.
Geiger-Muller or ionisation chamber detectors are generally the best for area
monitoring of alpha and beta radiation.
85
Very soft beta emitters (≤0.25 MeV) such as tritium, carbon-14, sulphur-35 and
calcium-45 may require initial concentrating before detection with thin window geiger
probes.
The TLD or QFD will measure all types of radiation except alpha radiation and very
low energy beta radiation, e.g. Tritium, carbon-14.
11.5.2 Units
The meter should read in SI rather than imperial units (American system), for easy
comparison with current standards.
11.5.3 Sensitivity
The meter should have sufficient sensitivity for the applications required. High
sensitivity may be required for measuring low level contamination. In this case, a large
surface area detector will be needed. However, if such an instrument is used to measure
high levels of contamination, partial saturation of the detector may result leading to a
low response. The response time (dead time plus recovery time) of the instrument may
be too slow for measurement of pulsed radiation fields (e.g. fractionated X rays) unless
the instrument has been specifically chosen for the purpose.
11.5.4 Interferences
Radio frequency fields (non-ionising radiation) will affect the meter readout unless the
detector is adequately shielded.
Principle of Operation: Radiation causes direct ionisation of the gas (usually air) in the
chamber. Ions are attracted to opposite electrodes and the resulting current is measured.
Usage: Ionisation chamber detectors can be used for beta, X, or gamma and sometimes
also alpha radiation as well (this may vary between brands).
These make excellent field instruments, but they can be heavy as a portable instrument.
Other advantages are:
86
• Energy response is fairly linear and mostly dependent on the chamber wall
thickness. Such an instrument has a wider linear range than a Geiger-Muller
tube.
Usage: Proportional detectors are common for alpha and neutron measurement.
Usage: They are excellent for many beta, gamma and X radiations. Digital audio
dosimeters are generally small Geiger-Muller detectors and they provide a readout of
dose and have alarm capabilities.
• Geiger-Muller detectors are small, rugged and have a large linear region and
a rapid response.
• They have long dead-times (100-200 msecs) where no pulse can be
registered, and may register a response to intense light or high temperatures.
A disadvantage with these units is that can be sensitive to high radiation fluxes,
exhibiting fold back (saturation of the tube and zero reading) acutely, in very low or
high radiation fields. If the electronics are well designed these problems can be
minimised.
87
Usage: The choice of the scintillant determines the type of radiation which will be
detected. Zinc sulphide is a common used scintillant for alpha detection and sodium
iodide is a commonly used scintillant for gamma detection.
Scintillation detectors are very sensitive and are generally used for low levels of gamma
or X radiation.
A disadvantage with these units is that they can be affected by magnetic fields. Another
problem is that all light must be excluded from the detector due to the principle used for
detection.
Usage: Previously used for personal dosimetry for most types of radiation. All radiation
types are now measured with a TLD
Their main disadvantage is that they are less sensitive than a TLD.
Usage: They may be obtained to measure for X, gamma, beta or neutrons. They are
used for short term assessment of total dose and are somewhat susceptible to knocks
and moisture.
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11.6.8 Neutron Detectors
Chemical reaction and activation detectors (specifically for neutrons) are also used for
radiation measurement. The type of neutron will determine the principle of detection
used.
Principle of Operation: The neutrons induce radioactivity in other materials, which can
then be measured. Chamber requires some shielding.
Principle of Operation: Detectable in the same way as fast neutrons but the chamber
has no shielding.
n + 10B → 7Li + 4He (α)
The disadvantages associated with this type of detector are that it also responds to γ and
it is very heavy.
11.6.9 Other
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12. THE PHILOSOPHY OF IONISING RADIATION PROTECTION .......................................... 91
90
12. THE PHILOSOPHY OF IONISING RADIATION
PROTECTION
12.1 Introduction
The magnitude of individual doses, the number of people exposed and the
likelihood of incurring exposure that was not anticipated, should be kept As
Low As Reasonably Achievable (the ALARA principle), economic and social
factors taken into account.
The exposure of individuals should be subject to dose limits and there should be
some control of risk in the case of potential exposures.
91
containing radionuclides can reasonably be regarded as the responsibility of operating
management, and even then, only in the following cases:
Optimisation of protection
The ICRP recommend that optimisation of protection should be carried out by the
regulation of practices. This is the reason behind many of the guidelines, Australian
Standards and codes of practice that have been incorporated as an adjunct to radiation
safety law in Victoria. The optimisation of protection only takes into account actual
exposures. Potential exposures are dealt with in a section 12.2.4.
Dose limits are recommended to cover a wide range of occupational situations and to
provide an upper limit to any constraints applied under optimisation of protection. In
setting dose limits for occupational exposure the ICRP have defined three subjective
terms in relation to the tolerability of the wider community towards the consequences or
risk of an exposure
• "Unacceptable".
The ICRP have aimed at setting the dose limits on the boundary between unacceptable
and tolerable in relation to a normal operation of any practice of which the use of
ionising radiation was a matter of choice. Exposures above the boundary between
unacceptable and tolerable may have to be accepted in abnormal situations such as
accidents.
92
In setting dose limits the ICRP has taken into account the following contributing factors
to health detriment:
• Probability of death.
The ICRP recommends a dose limit based on annual, average dose over a working life
time of 47 years. After examining mortality and morbidity data in their 1990
recommendations (ICRP 60), the ICRP have come to the conclusion that the total
effective dose to a worker over the period of his or her entire working life should not
exceed approximately 1 Sv, received uniformly, year by year. In theory the ICRP is in
favour of a life time dose limit for occupational exposure but recognises the practical
difficulties in controlling this while workers change jobs. Consequently a 5 year
exposure limit is given in addition to the annual dose limit.
The ICRP found that the skin and the lens of the eye may not be protected adequately
by a limit on whole body dose, particularly in the case of external exposure.
Consequently these tissues have been given different dose limits of their own.
The ICRP has established annual limits of intake (ALI’s) for a wide range of nuclides.
An ALI is the quantity of a radionuclide acquired as an internal contaminant which
would give an annual dose commitment of 20 mSV, considered over 50 years. Due
weighting is given to the effects of radiation to the various bodily organs. This dose is
related to “reference man” and does not take into consideration various physiological
differences.
Dose limits for occupational exposure are not intended to make any allowance for
medical or public exposure incurred by workers.
Protection of women
The basis for setting dose limits for women is the same as that for men except when a
woman is pregnant. In this case, the unborn child must be protected at a level that is as
restrictive as for a member of the public. In turn, this should restrict the work activities
of women during pregnancy to employment of a type that does not carry a significant
probability of high accidental doses or intakes.
93
12.2.1.2 Medical Exposure
Justification of practice
Optimisation of protection
The ICRP does not recommend any dose limits in relation to medical exposure because
doses must be given commensurate with medical purposes. Any attempt by regulatory
authorities to set dose limits for medical purposes may result in added detriment to a
patient.
Diagnostic and therapeutic procedures involving the use of ionising radiation should be
avoided during pregnancy unless there are strong clinical indications for their necessity.
94
12.2.2 Public Exposure
Public exposure includes all exposure to natural and artificial radiation sources that is
not classifiable as either occupational or medical exposure.
Optimisation of practice
The main aim of optimisation of practice in the control of public exposure should be to
develop practical restrictions on the sources of exposure. See Appendix B for some of
the codes of practice that provide guidelines in this matter.
Dose limits for public exposure are not intended to cater for potential exposures. The
ICRP has chosen a dose limit for public exposure which lies between unacceptable and
tolerable as defined by the ICRP and is based on the variations in existing levels of dose
obtained from natural sources.
The dose limit is intended to be applied to exposures that are the result of practices
whose use is a matter of choice. There is an annual dose limit and a dose limit that is to
be applied over a 5 year period. Radon in dwellings and in the open air and radioactive
materials whether natural or artificial, already in the environment are outside the scope
of limits for public exposure.
The ICRP has adopted an arbitrary reduction factor of 10 in deciding on dose limits for
the eye and skin tissue because the general population show a wider range of sensitivity
than the working population.
Dose limits for public exposure are not intended to cover exposures that are incurred by
a person in the course of their occupation.
The concept of health detriment does not include probabilities for potential exposures
due to the inherent difficulty in quantifying them. Nevertheless, every effort must be
made to control potential exposures. Potential exposures may be occupational, medical
or public.
95
12.2.3.1 Control strategies for potential exposure
Justification of practice
The estimate of detriment from potential exposures will be very difficult to quantify
prior to considerable experience being attained with the ionising radiation practice
concerned. A re-justification of practice may be necessary once a better estimate of the
contribution to detriment of potential exposure has been made.
Optimisation of practice
One must be careful that measures put into place to reduce the risk of potential
exposures do not increase the incidence of occupational exposures. The reduction in
public exposure by reducing incineration and increasing storage of waste may result in
an increase in potential occupational and public exposures.
The ICRP makes special provision for higher dose limits in the case of accidents or
emergencies. However, there are special conditions that apply to such situations and
any decision to apply such limits is the exclusive right of the Department of Health and
Community Services, Victoria in conjunction with the RPO.
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13. LIMITS OF ACCEPTABLE EXPOSURE .................................................................................. 98
13.3 LIMITS FOR AREA CONTAMINATION INTERNAL AND EXTERNAL EXPOSURE ................................. 100
97
13. LIMITS OF ACCEPTABLE EXPOSURE
The ICRP have stipulated the following dose limits in ICRP 61. The limits are formally
written into legislation in Victoria and have been adopted by the Department of Health
and Community Services, Victoria and the RPO.
Dose limit1
Application Occupational Public
Effective dose
20 mSv1 per year 1 mSv in a year3
averaged over discrete
periods of 5 years2
Annual equivalent dose in:
Notes:
1. The 20 mSv annual limit applies to the sum of:
The relevant doses from external exposure in the specified period.
The 50 year committed dose (to age 70 years for children) from intakes
(internal exposure) in the same period.
2. The effective dose may also be defined as 100 mSv averaged over 5 years and
must not exceed 50 mSv in any single year.
3. The average in a single year may fluctuate, provided that it does not exceed 1
mSv when averaged over 5 years.
4. The limitation on effective dose provides sufficient protection against
stochastic effects and applies to the skin of the face. The 500 mSv dose is
averaged over any 1 cm2 area of skin regardless of the area exposed. This
additional limit is needed to protect against deterministic effects from
localised exposures.
5. The ICRP do not define this limit for members of the public.
Table 17: Dose Limits
A supplementary limit applies to protect the unborn child because a dose to the uterus
can be taken to be the dose to the whole body of the embryo or foetus. This is an
effective dose limit of 2 mSv for the abdominal area for the remainder of the pregnancy.
98
An individual equivalent dose limit for the thyroid gland is no longer recommended by
the ICRP, although such a limit is stated in the NH&MRC publication on
"Recommended Radiation Protection Standards for Individuals Exposed to Ionising
Radiation" (currently enacted under legislation in Victoria).
The "non-stochastic" limit of 500 mSv annually has also been used for the thyroid, but
even this is not recommended in ICRP 60. All the dose limits given in ICRP 60 are
designed to prevent deterministic effects. The only tissues that have equivalent dose
limits of their own are the lens of the eye and the skin. The lens of the eye makes a
negligible contribution to effective dose and the skin may be subject to localised
exposures.
The RPO has imposed action limits on external radiation exposures to university
personnel. The action limits are set at 10% of each ICRP dose limit.
Any exposure above the action limit will be followed up by the RPO in association with
the RSO or deputy RSO and the individual concerned.
The ALI is given for individual radionuclides separately for ingestion and inhalation. 1
ALI is the limit of radionuclide which, when absorbed by inhalation or ingestion would
irradiate the worker to the committed effective dose limit of 20 mSv annually. Current
ALIs for common radionuclides are given in ICRP 61, and Table A3 in Australian
Standard 2243.4 (1994)int. The ALI values may be averaged over 5 hears to provide
some flexibility. They are designed to prevent deterministic effects.
For members of the public the ALI is 1 mSv, (AS2243.4). However, the NH&MRC has
not yet endorsed this value.
ICRP 60 stipulates that intakes of radionuclides for pregnant women working with
ionising radiation should be reduced to 1/20 of the ALI as soon as the pregnancy has
been declared. This limit will stay in force throughout the remainder of the pregnancy
and thus protect the unborn child.
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13.2.2 Limits for Area Contamination Internal and External
Exposure
One DAC is the air concentration of the radionuclide that would result in a worker
receiving one ALI through a single years exposure. A DAC is calculated as follows:
The DAC is derived from the ALI as defined in ICRP 61 as well as AS2243.4.
The DAC for members of the public is taken as 1/100 of the occupational ALI. This is
done on the basis that a member of the public in 24 hours, breathes 2.4 times the
volume of air that a worker does in 8 hours. In addition the member of the public
inhales the radioactive material for 365 days a year. Whereas the worker only inhales it
for 250 days.
ONE DWL represents the maximum allowable limit of surface contamination if the
effective dose limit is not to be exceeded on an annual basis for either occupational or
public exposure.
• If on the skin, the skin dose does not exceed the equivalent dose for the skin.
The ICRP and the Health Department of Victoria do not stipulate derived limits for
various radionuclides. DWL’s are set out in Appendix A of Australian Standard
AS2243.4. The DWL is dependant upon the radiotoxicity of the radioisotope as shown
in table 18.
100
Class Radiotoxicity DWL (Bq.cm-2)
I very high 0.01
II high 0.10
IV low 10.0
101
14. CONTROL MEASURES FOR IONISING RADIATION......................................................... 103
102
14. CONTROL MEASURES FOR IONISING
RADIATION
Once an ionising radiation hazard with unacceptable risk has been identified, suitable
control measures must be established. The following approach, from most to least
desirable, should be taken in deciding on control measures for a specific ionising
radiation source.
14.1.1Removal
Removal involves seeking an alternative to the use of ionising radiation for the
purpose. This is the most desirable option.
14.1.2 Substitution
14.1.3 Isolation
103
• Lead aprons to shield external exposure for X and γ sources.
This is the least desirable option and if chosen, should be used in conjunction with
other control measures.
• Warning signs.
14.2.1 Time
Consequently time spent in an area where significant exposure may occur must be
kept to a minimum. If the dose rate is known at a particular geographical location in
relation to a source of ionising radiation then it is possible to calculate the maximum
permissible time that may be spent in this area using a suitable portion of the
equivalent dose limit.
14.2.2 Distance
DR = AE (1)
6r2
DR = ΓA/d2 (2)
The inverse square law that relates dose to distance from a point source is also used
in the following form:
Examples of calculations using the inverse square law are contained in Appendix C.
14.2.2.2 Beta
Beta rapidly loses energy in its passage through air, thus there are no straightforward
equations to relate the behaviour of the dose rate from beta radiation as a function of
distance.
14.2.3 Shielding
The purpose of shielding is to ensure that the dose received by persons is as low as
reasonably achievable and is well below the dose limits.
Sealed and unsealed sources and apparatuses which emit penetrating ionising
radiation (e.g. X, gamma, beta or neutron radiation) may need to be shielded.
Shielding required depends on the type and energy of the radiation emitted and its
intensity.
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14.2.3.2 Shielding for various forms of radiation
Alpha radiation
Alpha radiation does not require shielding due to its extremely low penetrating
capability. It will be stopped by a sheet of paper or the outer layer of human skin.
Beta radiation
For shielding beta radiation, low atomic number material (e.g. perspex, aluminium)
is preferable to minimise production of bremsstrahlung. In general, 10 mm of
perspex is used to shield the most powerful beta emitters (1-10 MeV range) and to
stop the formation of Bremsstrahlung. Several millimetres of aluminium will afford
the equivalent attenuation.
X or gamma ionising radiation may be generated from its source as either a "broad
beam" or a "narrow beam". In the case of a narrow beam, any scattered radiation is
lost. In the case of a broad beam configuration, some scattered radiation may be
brought back into the beam causing "buildup".
Is = Iμse-μt
In the case of a broad beam configuration, a buildup factor (B) is included in the
attenuation equation:
For shielding gamma and X radiation, high atomic number material (dense) is often
used (e.g. lead, depleted uranium or tungsten). Lower atomic number material (e.g.
steel, concrete or water) can be used but in correspondingly greater thicknesses.
The thickness of a particular shield that reduces the dose rate to half is termed the
"half value layer" (HVL). The HVL is usually listed for various materials and
various energies of radiation:
HVL = 0.693/μ
106
Lead 1.1 Cobalt-60 gamma
Iron 2.0 Cobalt-60 gamma
Concrete 6.3 Cobalt-60 gamma
The number of HVLs (N) may be determined by knowing the extent of attenuation:
Is = Ius
2N
where Is = Shielded Intenstity
Ius = Unshielded Intensity
The tenth value layer (TVL) which gives the thickness of a material that attenuates
dose by a factor of 10 is also sometimes useful:
TVL = 2.303
μ
Is = Ius
10N
Neutrons
If the shield is made of heavy elements (e.g. lead), then inelastic scattering or capture
mechanisms may predominate, resulting in the activation of the shield material to a
radioactive state that continues beyond the time of irradiation with neutrons.
The most common situation requiring shielding of two different types of radiation is
that where beta and gamma isotopes are being used or stored together. In this case it
is prudent to use a shield for the beta radiation closest to the sources (i.e. perspex or
aluminium) and this should be followed by a shield suited to gamma radiation (e.g.
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lead). Note that a reversal in the order of theses shielding materials in relation to the
source may lead to the generation of Bremsstrahlung radiation.
These aspects of a work area must be of the highest standard. As routine practice the
work area should be checked for contamination before and after any work procedure
and in any case, at least once per day.
Adopt a policy of using the smallest amount of the least toxic isotope suitable.
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14.4 Administrative Controls
14.4.1 Precautions for Using Ionising Radiation
Procedures for use of ionising radiation should be formulated by the RSO and
deputy RSO in accordance with AS2243.4 requirements.
Where monitoring indicates that a person working in an area could receive three
tenths or more of the exposure limit, such an area shall be classified as a DRA and
shall come under the control of a RSO and deputy RSO. Most DRAs within Monash
University are laboratories. They must comply with the stipulations of section 31 of
the Policy Statement.
The internationally recognised radiation warning sign (as shown in Figure 19) shall
be displayed at the entrance to each DRA.
109
Figure 19:The Radiation Warning Sign
Work out of hours is not encouraged but if it must be done, compliance with section
27 of the Policy Statement is required. It is preferable to have a second person
present.
Design features of any laboratory where ionising radiation is used should be based
on section 11 of AS 2243.4 (1994).
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15. STORAGE OF RADIOACTIVE WASTE AND SOURCES OF IONISING RADIATION .... 112
15.4 CONTAINERS FOR STORAGE OF RADIOACTIVE SOURCES AND WASTE ........................................... 114
15.5 SHIELDING FOR LONG TERM RADIOACTIVE SOURCES AND WASTE ............................................... 114
111
15. STORAGE OF RADIOACTIVE WASTE AND
SOURCES OF IONISING RADIATION
15.1 Introduction
• Sources that are in regular use but need to be controlled in order to avoid an
incident as defined in section 19 of this manual.
• Placing into short term storage in the medical or chemistry waste store,
any material which is medium term waste and may be disposed of after a
period of storage not longer than one year.
• Placing in the long term store any material that cannot be disposed of
within one year.
The hospital has its own store, which can only hold low level radioactive waste (see
section 16.2) which is destined for immediate disposal.
The Monash Department of Medicine has its own storage facility for radioactive
waste. Although space is extremely limited, it can hold some medium term waste.
112
15.2.3 Alfred Hospital
The hospital has its own store, which can only hold low level radioactive waste that
is destined for immediate disposal.
Does not have a dedicated radioactive waste store, as the usage (at present) of
radioisotopes is limited to low activity emitters.
Does not have a dedicated radioactive waste store as the usage (at present) of
radioisotopes is limited.
Does not have a dedicated radioactive waste store, as the usage (at present) of
radioisotopes is limited to low level emitters.
There are two short/medium term stores in existence, which are cleared by a monthly
collection. The keys to these are held by the RSOs and deputy RSOs of the user
departments:
• Chemistry store
• Medical store
There is also now a long term radiation waste store managed by the RPO.
The requirement for labelling of short term waste that is destined for immediate
disposal are set out in section 16. In the case of medium and long term waste or
other ionising radiation sources requiring storage in any of the radiation stores
mentioned in 15.2, a permanent label with the following information must be
affixed:
Acidic or alkaline waste should be neutralized before storage for any length of time.
Containers used to transfer radioactive materials to and from the store should be
designed to prevent accidental release of the material if they are dropped or upset.
Containers must be chemically resistant to their contents and not too heavy to lift.
No container should hold more than 5 litres of liquid radioactive material.
"High level radioactive" waste (radioactive waste other than low level) must be
contained according to its rate of decay. Accordingly shielding will be required to
ensure that the dose rate on the inside of the store is no more than 5 mSvh-1 due to all
packages. The dose rate external to the store must be no more than 2.5 mSvh-1 to
conform with the public dose limit.
All sources must be stored in secure locations. That is they should not be left in
unlocked locations that may be accessed by non radiation workers.
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16. DISPOSAL OF RADIOACTIVE WASTE................................................................................. 116
115
16. DISPOSAL OF RADIOACTIVE WASTE
16.1 Introduction
In all cases, the disposal and handling of radioactive waste must not result in any
person becoming exposed to ionising radiation above the dose limits detailed in
section 13 of this manual. The limiting exposure factor in handling waste is the
radiation worker effective dose limit (which is effectively 5 μSv/h based on the 20
mSv limit). In addition, all waste handling procedures must satisfy the ALARA
principle.
Radioactive waste in this manual means “low level” radioactive waste. The
International Atomic Energy Agency have provided the only definition of "low level
waste". It is that waste produced by the use of radioisotopes in industry, medicine,
research or by nuclear power operations. This category includes a negligible amount
of long-lived radionuclides that have half lives greater than 30 years. It does not
include large concentrations of radioisotopes that require handling and transportation
behind gamma shielding, or ones that generate appreciable heat from radioactive
decay.
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State of Waste Form of Waste
Solid -Tissues, sharps, instrument and other
non-flowing matter
-Animal carcasses or pieces thereof
Liquid - Bodily fluids
- Contaminated water
- Chemicals in the liquid state
Airborne matter
- Gases
- Vapours
- Dusts
High level waste includes all radioactive waste that does not fullfil the low level waste
definition. Types of high level waste at Monash University are almost exclusively in the form
of sealed sources.
Liquid or gaseous radioactive waste may be diluted with water or air respectively and dispersed
into the environment. Current limits for disposal of certain radionuclides in this manner are
given in part 12 of the Health (Radiation Safety) Regulations 1994. These limits apply to each
of the University's campuses as a whole. Consequently, the RPO should be consulted to
determine the amount of activity that each department is entitled to dispose of.
Long lived radioactive waste in any physical form may be concentrated and contained. In the
case of radioisotopes with very long half-lives consideration must be given to the life of the
container. As yet there is no national repository for long lived radioactive waste. Such waste
should be stored in the University's long term storage facility at the Clayton campus.
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16.3.3 Delay and Decay
Short lived isotopes with current activities above the limits that permit immediate disposal can
be stored whilst they decay. These should be labelled in accordance with section 15.3 of this
manual and stored in the long or short term radioactive waste store depending on the length of
time until disposal.
Radioactive materials having a dose rate on the surface of the package of >5 μSv/hr must be
packaged, labelled and transported in accordance with the Code of Practice for the Safe
Transport of Radioactive Substances 1990.
All radioactive waste must be double packaged and one of the layers shall be waterproof.
Solid waste intended for landfill should be packed into closed drums, multiple opaque plastic
bags or multi-layer paper and plastic bags. A foot operated bin with a double liner is a very
suitable waste receptacle for solid waste. All container types except metal and large glass
bottles are suitable for incineration.
Syringe needles, pipette tips and any other sharp objects should be packed in closed, approved
sharps containers so that they will not protrude from the packaging.
118
Animal carcasses or any putrescible waste must be double bagged as for solid waste and stored
in a freezer until disposal.
Scintillation vials must be collected in sealable plastic buckets provided by the waste removal
contractor.
Where danger from contamination on the external surface of the package exists, the package
should be covered with an additional layer of packaging. When choosing a container for
chemical disposal, the compatibility of the chemical with that substance should be taken into
account. Waste should be disposed of frequently and individual containers should not be
allowed to become too heavy to lift. It is good practice to choose containers with limited
capacity.
Provided that the outer dose rate limit of 5 mSv/hr has been met there is no legal requirement to
label the outside of the package indicating that it is radioactive. It is considered undesirable to
do so. However, the inner packaging that is not visible must be labelled as radioactive. Note
that the requirements for labelling of low level waste prior to disposal vary considerably from
labelling waste for storage or transport.
All waste containers of radioactive material must be labelled with a perishable paper label
showing the following details in order that the costs of waste disposal can be distributed by the
RPO. Waste not labelled in this manner shall not be cleared by the RPO for removal.
Department:
Radionuclides:
Activity:
Description of contents:
Date of deposition:
Name of responsible person:
Low level solid waste including animal carcasses is the only radioactive waste that is permitted
to be disposed of at a municipal tip. The tip must be approved specially for the purpose and an
approved procedure must be followed. These stipulations are laid down by the EPA, Victoria.
The following limits apply to dumping solid waste to landfill:
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Regardless of the radionuclides contained in the package, the maximum dose rate at the surface
of the package must not exceed 5 μSv/h. This approximates on some of the mini monitor count
rate meters to an upper limit of 200 counts per second. However, calibration of the each
monitor is obviously important.
These limits must be checked by the generator of the waste prior to removal of the package
from the campus.
• For radionuclides from the natural uranium or natural thorium decay series,
including the parent uranium and thorium radionuclides themselves, no more than
250 Bq of each per kg of waste.
• For other radionuclides having a half life of 1 year or greater, 0.1 ALI
• For other radionuclides having a half life between 60 days and 1 year, 1 ALI
All radioactive waste that is disposed of to landfill must be enclosed in two layers of packaging,
of which at least one layer shall be waterproof. The most commonly used containers are plastic
lined paper bags. Note that it is not acceptable, under any circumstances to dispose of sharps
to landfill.
The Environment Protection Authority has placed stringent requirements on the permissible
levels of emissions from all types of incinerators, and gives guidance on what can be burnt and
the temperatures appropriate for incineration. This includes uncontaminated animal carcases
and bedding and some paper products.
Under no circumstances are flammable solids, sharps and vials containing organic solvents
suitable for low temperature incineration. Glass vials with metal caps are not suitable for
incineration due to the explosion hazard they present.
It is the responsibility of the generator of the waste to check that these levels are complied with
prior to the waste leaving the laboratory.
It is not permissible to dispose of liquid radioactive waste to landfill in a tip due to the risk of seepage
from the tip site to ground water or later earth works.
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16.7.2.2 Disposal by incineration
Bulk solvents and liquid bio-hazardous matter that is contaminated with radioactivity are the
most common types of radioactive waste incinerated. The rules for incineration of liquid
radioactive waste are the same as those for incineration of solid waste. (See 16.7.1 above)
Low activity radioactive material may be discharged into a sewerage system, if the material is
readily soluble and dispersible in water and:-
• the quantity discharged in any seven day period does not exceed 20 times the ALI by
ingestion for that radionuclide; or
• the quantity discharged in any one period of 24 hours does not exceed the quantity
which, if diluted by the average daily quantity of sewerage discharged into that
system from those premises, would result in an average concentration equal to the
appropriate maximum concentration permitted under section 73 Part 12 of Health
(Radiation Safety) Regulations 1994.
These limits apply to each of the University's campuses (i.e. Sites holding a licence for the use
of unsealed sources). The RPO should be consulted if any site is unsure of the quantity of
radiation it may dispose of.
Drains used for disposal of liquid radioactive waste shall be clearly and permanently labelled,
and should not be connected to non-radioactive waste lines until outside the building.
Liquid radioactive waste discharged into laboratory sinks shall be diluted with copious amounts
of water.
Radioactive waste in the form of gases should be vented to a fume cupboard or local exhaust
system and heavily diluted with air. It will be necessary to contact the RPO in order to
ascertain the limits on emission that are required by law. Alternatively, radioactive aerosols
may be contained by filtrations.
A contained area that is easily decontaminated and protects people in the vicinity (e.g. a glove
box) is the best option. Fume cupboards or local exhaust will protect the operator but
decontamination when maintenance work is required, is very difficult.
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17. PROCEDURES FOR ORDERING, PURCHASING AND RECEIPT OF SOURCES OF
122
17. PROCEDURES FOR ORDERING,
PURCHASING AND RECEIPT OF SPURCES OF
INISING RADIATION
17.1 Introduction
The ordering, purchasing and receipt of sources of ionising radiation shall be carried out in
accordance with the requirements of section 23 of the Policy Statement.
All orders of sealed radioactive sources must include a list of officers authorised by the Head of
Department to receive the goods.
Orders for unsealed sources by phone must be confirmed in writing. Written records must be
kept of the order with a list of designated officers authorised to receive the consignment.
Labels (as below) are to be fixed to all consignments of radioactive sources, identifying the
receiving department's name, names and phone numbers of at least two designated officers,
who must receive the consignments when delivered. The laboratory manager then the RPO are
to be contacted (and included as the last contact point) if none of the designated officers are
available.
Department:
1.
2.
3.
There must be a central or designated delivery point per department for the receipt of
radioactive sources. The central or designated delivery point must have a separate clipboard
with the list of names and contact phone numbers for designated officers authorised to receive
123
radioactive consignments. Upon receipt of a radioactive consignment, a designated officer
must sign the label on the package and the entry in the clipboard.
Security of radioactive materials must be ensured at all times. i.e. At no time are radioactive
materials to be left unattended on loading docks or at a designated receiving point.
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18. TRANSPORT OF RADIOACTIVE MATERIAL .................................................................... 126
125
18. TRANSPORT OF RADIOACTIVE MATERIAL
Section 24 of the Policy Statement details Monash University policy for transport of radioactive
materials.
The transport of radioactive material by road, sea or air and the storing, packing and stowing of
that material in relation to transport is currently regulated by Part 11 of the Health (Radiation
Safety) Regulations 1994. These call up the Code of Practice for the Safe Transport of
Radioactive Substances 1990 (hereafter referred to as the "Australian Code"). This code is an
Australia wide document in its application and is modelled on the International Atomic Energy
Agency’s Regulations for the Safe Transport of Radioactive Material 1973 (hereafter referred
to as the "International Code") which is an international document in its application.
For air transport of sources of ionising radiation the most current edition of the IATA
(International Air Transport Association) Dangerous Goods Regulations should be consulted.
These are the most stringent of all transport requirements.
The IAEA Transport regulations form the basis of all Australian State legislation for
the safe transport of radioactive materials. Section 11 of Health (Radiation Safety)
Regulations, paragraphs 61, 62, 64 and 66 are particularly relevant.
The IAEA Transport Regulations are based on meeting four basic safety
requirements:
• type A;
• type B;
• low specific activity;
• low level solid;
• exempt.
Radioactive packages are classified into three categories based on the external
radiation at the surface of the package and at a distance of 1m from the surface. The
126
radiation level (mrem/h) at a distance of 1 meter from the surface of the package is
referred to as the transport index. The three categories are :
The above surface radiation levels have been adopted on the basis of safe operating
experience. The transport index is used to control the number of packages that can be
grouped together, to ensure that the external radiation levels from a group of packages
do not exceed safety levels.
127
19. INCIDENTS INVOLVING IONISING RADIATION.............................................................. 129
128
19. INCIDENTS INVOLVING IONISING
RADIATION
19.1 Introduction
Monash University policy for accident and emergency response is detailed in sections 22 and
26(iv) of the Policy Statement. In addition, the Monash University "Policy on Incident
Reporting Investigation and Recording" (OHS Policy No. 1/89) contains relevant information.
- Exposure to personnel above the Monash University action levels for ionising radiation
dose.
- Unauthorised entry to an area where source/s of ionising radiation are being used or
stored.
- Any factor that causes damage to a room (or its contents) in which a source of ionising
radiation is located.
The procedure for dealing with an emergency involving ionising radiation is as follows. It is the
responsibility of the first able-bodied person on the scene to initiate the procedure.
1. Recognise that an emergency possibly involving ionising radiation and other hazards is
occurring.
3. Notify one of the following persons in order of priority. It then becomes the
responsibility of this person to take charge of the emergency. The most suitable person
129
to take care of the emergency is usually the RSO, deputy RSO or the RPO. The RPO
must be called in any incident that is assessed as "serious", "significant" or "lost time"
(in accordance with the policy on incident reporting, investigating and recording), by
those first at the scene.
• Immediate supervisor
• The RSO
• The Deputy RSO
• The Safety Officer
• The RPO
• The Resources Manager
• The Head of Department
The RPO is obliged to notify the Department of Health & Community Services,
Victoria and the Police in certain circumstances.
4. The person in charge of the emergency may then elect to notify emergency services. i.e.
the fire brigade or ambulance. The person in charge may delegate responsibility to a
second person to fetch the departmental radiation emergency response kit (section 19.4).
5. Ascertain the type of hazards and the relative risks present and the personal protective
equipment that will be required to stop the emission, assist casualties and perform the
cleanup. In doing this the person in charge should try to answer the following points:
d) Likely area covered by the hazard and consequently the area that needs
to be barricaded.
130
6. The person in charge should then ensure that persons going into the area are properly
protected and that there are facilities for their decontamination. The following
procedures should then be carried out:
7. The person in charge may order the removal of the barricade when contamination
monitoring confirms that the level of contamination to areas is below the DWLs given
in section 19.5.2 of this manual.
8. The victim of the incident or the person who first reported it is responsible for recording
the incident in accordance with section 19.7 of this manual.
The RSO should obtain a portable spill kit; these are commercially available. Other useful
items that should be kept with the kit include, personal dosimeters, monitors suitable for
measuring contamination, respiratory protection devices and protective clothing.
It shall be the responsibility of the RSO or Deputy RSO to maintain the kit in a condition ready
for use at any time.
The RSO or Deputy RSO should investigate the cause of the high exposure without delay,
complete a minor incident form and provide the RPO with a written explanation. RSOs should
be aware that the timing of reporting is critical in the case of a known or suspected exposure
that exceeds 5 mSv in one week. The RPO must report all such exposures to the Health
Department within 48 hours of their known or suspected occurrence.
131
The RSO or Deputy RSO must also check or arrange to have checked the extent of internal
and/or external contamination sustained by the individual concerned where the type of incident
makes internal contamination a possibility (see section 10).
External contamination may be measured using an appropriate count rate monitor. All clothing
and any exposed flesh should be checked. In accordance with the Health (Radiation Safety)
Regulations 1994, the following DWLs signal the requirement to decontaminate the individual
and the clothing and contain the contamination, see section 19.6 of this manual:
In the case of a serious incident any obvious injury should be treated prior to decontamination
of the victim, where this does not present significant risk to emergency response personnel.
Person(s) involved in such an incident shall be aware of contamination risk to themselves and
shall participate in special monitoring programs as deemed necessary by the RPO.
To conform with the “Policy on Incident Reporting, Incident Investigation and Recording” any
exposures recorded as being above the Monash University Action Limit (480 μSv/ 12 week
exposure whole body dose, 1 mSv/week for extremities) should be reported as significant
incidents.
When an accidental exposure (e.g. via spillage) of personnel is believed to be above 1mSv this
should be immediately reported as a Significant incident (see Para. 36 Stat Rules, Health
(Radiation Safety) Regulations 1994).
The RSO or Deputy RSO should initiate the prevention of further spread of contamination,
once it is safe to do so. All surfaces within the area should then be decontaminated to below
1DWL
Small spills of radioactive material that present no radiological hazard to persons should be
dealt with by the radiation worker under the guidance of the person in charge of the incident.
Rubber gloves are the basic personal protection for spill handling.
Spills of liquids should be absorbed with blotting paper, paper towels or tissues. Dry materials
should be carefully wiped up with absorbent tissues moistened in water.
Where the level of radioactive contamination cannot be reduced below the DWLs specified
above the following action must be taken:
· In the case of immovable contamination where cleanup has already been undertaken,
cordon off the area or cover it with a shielding material to prevent unnecessary exposure
for the time that it takes for the radioactivity to decay to below 1 DWL e.g. A lead plate
is put over a floor tile contaminated by gamma radiation.
132
· In the case of movable contamination where cleanup is not feasible due to the risk
involved either; cordon off the area, or cover it with a shielding material to prevent
unnecessary exposure for the time that it takes for the radioactivity to decay to below 1
DWL.
In any case of suspected theft or loss of a source of ionising radiation the RPO must be notified.
The RPO will then contact the Police and the Health Department of Victoria.
The RSO or Deputy RSO shall make use of available options such as withdrawal of permission
to use radioactive materials or provisions of disciplinary procedures. In this case, it will be
necessary for the Head of Department to become involved.
The RSO or Deputy RSO shall make use of available options such as withdrawal of permission
to use radioactive materials or provisions of disciplinary procedures. In this case, it will be
necessary for the Head of Department to become involved.
Firefighting takes precedence over contamination control, but all reasonable efforts should be
made to minimise the spread of contamination, particularly at the clean-up stage.
Officers of the attending Fire Brigade should be informed in advance of the possible hazards
due to ionising radiation. This is the responsibility of the person in charge of the incident.
19.6 Decontamination
19.6.1 Introduction
The most important rule with decontamination is to weigh up the benefits of decontamination
versus the risks of cleaning up of highly radioactive material. It may be more appropriate to
wait for decay to render the material less radioactive, prior to starting a clean up. Specific items
that are contaminated may be easily dealt with by disposal. Failure to adopt this approach may
expose clean up personnel to unacceptable radiation doses.
133
Current radiation safety and environmental protection law prohibits the disposal of any type of
radioactive waste to the sink except in very controlled situations. All waste generated by a
decontamination exercise must be collected and the advice of the RSO or deputy RSO sought
prior to disposal (see sections 15 and 16 of this manual).
Initially, the first aid requirements of any contaminated personnel should be attended to.
Contaminated clothing should then be removed and personal decontamination should begin as
soon as it is safe for medical personnel to do so. It is important to reassure the patient before,
during and after the procedure. Generally, decontamination should proceed outwards from the
orifices and any wounds, as these represent the greatest risk of entry of radiation into the body.
Eyes should be irrigated with water, saline solution (1 percent common salt solution) and then
water again. A standard clean plastic wash bottle is a convenient applicator.
Contaminated wounds should be washed under a fast running tap and bleeding encouraged. If
on the face, take care not to contaminate the eyes, mouth or nostrils.
Skin and hands should be given one of the following treatments (in order of increasing
severity):
- Wash with soap and water and scrub lightly with a soft nail-brush.
- Wash and scrub with a detergent.
- Rub gently with a cotton wool pad soaked in a complexing agent (eg. Cetavlon).
- Place vaseline® or a similar skin cream over the area and cover it with tight fitting
cling-wrap or a rubber glove (in the case of hands) for several hours, prior to washing.
- Wash with a solution of 5% sodium hypochlorite (household bleach). Use 1% solution
for the face and neck and take extreme care around the eyes.
- As a last resort, immerse the hands in saturated potassium permanganate solution, allow
to dry and remove stain with 5 percent sodium metabisulphite solution.
- Medical authorities may attempt surgical removal of contamination.
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19.6.2.2 Internal decontamination
Initially, the mouth should be washed copiously with water. If this does not remove the
contamination it should be washed several times with hydrogen peroxide solution (one
tablespoon of 10% solution to a tumbler of water) followed by copious washings with water.
The victim must not be allowed to swallow the contaminated saliva and washing solution.
Many drugs and chemical substances have been advocated in the past for reducing absorption
or enhancing elimination of internally absorbed radionuclides. The Health Department of
Victoria now only advocates the use of such substances in cases of extreme exposure (i.e. life
threatening) and only after consideration of individual circumstances. No person should
undertake to treat a victim for internal radioactive contamination without first consulting the
RPO and the Occupational Health Physician.
Attempt all decontamination procedures in a fume hood if possible, in order to contain splashes
and aerosols. The equipment should be dismantled as far as possible. Decontamination should
be continued until monitoring shows that contamination is below 1 DWL (section 19.5.2).
Wash with mineral acid (chromic acid cleaning solution or concentrated nitric acid),
ammonium citrate, trisodium phosphate, ammonium bifluoride or detergents and rinse
thoroughly, avoiding splashing. When the glaze on porcelain is broken, or when active
solutions are heated to extreme dryness in glass, decontamination is very difficult and it is
usually more appropriate to discard such items.
- Use dilute mineral acids (nitric or a weak solution of inhibited phosphoric acid), a 10%
solution of sodium citrate, or ammonium bifluoride. Care should be taken as some
radioisotopes may become volatile upon reaction with acids. e.g. Iodine.
- Use hydrochloric acid only when all other procedures for stainless steel fail.
Hydrochloric acid is good decontaminant because it removes some of the surface,
although the procedure results in etching of the stainless steel, which makes it less
desirable for future use. It has been demonstrated that brass polish is an excellent
decontaminant for brass.
- Customised cleaning baths such as degreasers or ultrasonic baths may be used however
they then may present a problem as a contaminated object themselves.
135
- Light sandblasting - only after discussion with RPO.
Plastics may be cleaned with soap and water, ammonium citrate, dilute acids or organic
solvents (as appropriate for the particular plastic). In the case of plastic protective clothing, it is
often easier to avoid contamination by smearing PVC suits with barrier cream, which is then
easily washed off in soap and water. Plastic suits should never be cleaned with solvents whilst
being worn.
Floors and benches contaminated with radioactive material should be cleaned carefully as
described below using care not to spread contamination.
If the contamination is loose and dry, use masking or adhesive tape to trap small areas of it.
Never sweep dry radioactive contamination as a possible inhalation hazard may be created; a
wet mop should be used. If a wet mop will not remove the contamination, proceed with a
method suitable for the particular surface material. Some methods outlined below.
• Linoleum:
Wash with a solvent to remove all traces of wax, being mindful of the possible hazards
involved, namely inhalation of the solvent vapour and skin absorption of the solvent
liquid. Attempt this process only after discussion with the RPO, as suitable personal
protective equipment may be needed for prevention of solvent exposure.
Kerosene, ammonium citrate solution or diluted mineral acids may also be suitable, but
care should be taken not to dissolve sealing compounds around the edges and between
cracks of the linoleum.
• Ceramic tile:
Wash with a mineral acid such as inhibited phosphoric acid containing a wetting agent
or ammonium citrate or tri-sodiumphosphate.
• Paint:
Soap and water, 10% hydrochloric acid or a gel type paint stripper may be used.
136
• Concrete:
Clean as for ceramic tile or use inhibited hydrochloric acid. If these measures fail,
concrete must be removed.
• Wood:
Wood must be planed. Avoid sanding as this may create a radioactive dust hazard.
If these do not work then the contaminated material may need to be removed for disposal.
Alternatively the area may be shielded until it decays if appropriate.
Where any incident involving ionising radiation occurs, the procedures set out in the Monash
University "Policy on incident Reporting, Investigation and Recording" are to be followed with
the following exceptions:
·The RSO and Deputy RSO will replace the Safety Officer.
·Investigation of such incidents should involve the RSO or Deputy RSO and possibly,
the RPO.
·After the immediate supervisor and the RSO or Deputy RSO, the person to call in a
radiation emergency is the RPO.
137
20. RECORD KEEPING ................................................................................................................... 139
138
20. RECORD KEEPING
20.1 Introduction
Records are to be kept in accordance with Section 21 and Appendices 1 and 2 of the Policy
Statement and in relation to requirements in the Health (Radiation Safety) Regulations 1994.
Radiation dose records for each person monitored shall be kept for a period of 50 years. Upon
request they shall be made available for inspection by the individual staff member involved as
well as the RPO, the Occupational Physician or Health Department of Victoria personnel.
The RPO shall maintain a central registry of records including the following details:
- Name of wearer
- Date of issue and return of dosimeter
- Type of dosimeter
- Dose recorded
- Effective dose recorded for each year
A summary of the radiation dose record shall be available to each radiation worker when he/she
leaves the University.
Survey records from monitoring of levels of external radiation, surface contamination and
airborne contamination must be retained for a period of 6 years in a register containing the
following information and maintained by the RSO or deputy RSO:
- Date
- Areas surveyed
- Purpose of survey (e.g. surface contamination)
- Instrument used
- Results
139
20.4 Monitoring Equipment Calibration Records
Calibration information shall be kept by the RSO for the lifetime of an instrument or the
lifetime of results that are generated by it; whichever is the greater length of time. The
following calibration information is to be kept in a register and displayed on the instrument:
- Instrument name/number
- Serial number
- Calibration factor to be applied (if it exceeds + 20%)
- Date calibrated
- Date next calibration required
- Calibrating officer/organisation
Records of licences shall be kept in accordance with section 16 of the Policy Statement and
administered by the RPO.
The RPO shall maintain an inventory of all types of sources of ionising radiation which
contains the following information:
· Records to account for all sources of ionising radiation that are borrowed, lent, disposed
of or purchased by Monash University or that change hands between University
departments.
Complete records of receipt of radioactive materials shall be kept by the RSO or Deputy RSO
and will include radionuclide identity, activity, chemical form, date of purchase and place of
storage. The RPO must be provided with a summary of information on all sources of ionising
radiation purchased with the permission of the RSO or deputy RSO.
The RSO and Deputy RSO shall keep records of the usage of all types of sources in a
log book. For unsealed sources a record shall be kept of every fraction dispensed from
140
the original stock and will include: an identifier for the stock solution, activity used,
volume used, purpose, method of disposal and the time and date of taking the aliquot.
- Activity used.
- Method of disposal.
141
21. RESEARCH ACTIVITIES ......................................................................................................... 143
21.2 RESEARCH INVOLVING THE ADMINISTRATION OF IONISING RADIATION TO LIVE ANIMALS .......... 144
142
21. RESEARCH ACTIVITIES
Section 28 of the Policy Statement sets out specific requirements for this type of research at
Monash University.
The Health Act 1958 and the Health (Radiation Safety) Regulations 1994 control all uses of
ionising radiation in Victoria. There are specific requirements relating to research projects
involving the irradiating of Human Volunteers, that is, persons who do not receive a direct
benefit, either diagnostic or therapeutic, from the administration of ionising radiation.
Two separate licences are required before any work involving the exposure of Human
Volunteers to ionising radiation is allowed to commence.
1) Institution Licence:
2) Operator Licences:
These licences are to be paid for by the department directly involved in carrying out
the research.
These Licences are obtained from the Department of Health and Community services through
the RPO.
143
Information to be provided to the RPO with all applications for licences:
* The RPO must be notified when any research projects are completed, so that the Department
of Health and Community Services can be informed and the projects removed from the licence.
Section 29 of the Policy Statement details Monash University policy requirements for the
irradiation of live animals. In addition to this the following requirements shall apply:
· All projects shall have the approval of the Monash University Animal Ethics Committee
prior to their commencement.
· Animal rooms and cages containing contaminated animals are to be posted with
"CAUTION RADIOACTIVE MATERIAL" signs (see section 14.4.2), and the
entrances to rooms restricted to authorised personnel.
· Authorised animal care personnel must be provided with appropriate personal protective
equipment, radiation area monitoring equipment and personnel monitoring devices.
Investigators must provide adequate instruction in the use of these devices. Periodic
monitoring of the animals and rooms shall be made by investigative personnel
instructed in the use of monitoring equipment.
Routes of metabolism and the form of excreted radio labelled material must be taken into
consideration in regard to safe handling of animal bedding, cages, room surfaces, and room air.
Plastic backed absorbent pads, plastic bags, and other items should be used in animal wards for
containment of isotope spills or waste. Animal carcasses, contaminated bedding, and
equipment must be surveyed for radioactivity and provisions made for decontamination or
disposal.
The researcher is responsible for the proper disposal of radioactive wastes, decontamination of
equipment, and the final decontamination of containment areas after each set of experiments.
Dead animals must be placed in leakproof double walled plastic bags that are sealed prior to
144
removal from the containment for disposal. Animal litter must be disposed of separately in a
similar manner. They may require freezer storage until activity level has decreased.
It is preferred that animals given radioisotopes be housed in separate rooms by species and
researcher. Special ventilation, surface preparation, drainage, or other room design
requirements should be considered. To protect against undue radioactive contamination, all
surfaces should be non-porous and easily washable. Cracks and crevices should be sealed.
Continuous rubber or vinyl, or linoleum, applied over a floor will provide adequate protection,
since these materials are non-porous and contamination must be able to be readily removed.
145
22. RADIATION SAFETY TRAINING ........................................................................................... 147
146
22. RADIATION SAFETY TRAINING
22.1.1 General
Non-radiation workers includes all staff and students who do not work with ionising radiation
as part of their jobs but do work within departments where ionising radiation is used. Their
training is the responsibility of the Departmental RSO and Deputy RSO, and should be done at
the first available opportunity after their arrival within the department.
22.1.2 Type
The content of format and training shall be the first part of induction training as described in the
Policy Statement.
"New radiation workers" includes all staff and students within a particular department who
have never been trained in the principles of ionising radiation safety. These people may be
already working with radioactive substances or they may be intending to begin work shortly.
As far as possible, the training must be done prior to commencing work with ionising radiation
and is the responsibility of the RSO and Deputy RSO.
The format and content of training shall be the second part of induction training as described in
the Policy Statement.
"Experienced radiation workers" includes all staff and students within a particular department
who have undergone basic training as in section 22.2 and require additional specialist training
for special applications of ionising radiation use. The training is the responsibility of the RSO
and deputy RSO.
The content and format of the training shall be as detailed for radiation workers in the Policy
Statement.
147
22.4 RSOs and Deputy RSOs
It is assumed that RSOs and deputy RSOs have completed training and are well versed with the
principles taught in sections 22.1, 22.2 and 22.3. Training of the individual who holds this
position is compulsory and must be repeated at least every five years. The training course is the
responsibility of the RPO.
The content and format of training shall be as described for RSOs and deputy RSOs in the
Policy Statement.
148
Glossary
Absorbed dose (D) - the energy absorbed by matter per unit mass of irradiated
material. Averaged over a specific organ or tissue. The SI unit of absorbed dose
is the Joule per kilogram. The special name is Gray (Gy).
Atomic number (proton number) (Z) - the number of protons in the nucleus of
a particular element. It is equal to the number of electrons orbiting the nucleus of
a neutral atom.
Activity (A) - the average number of spontaneous nuclear transformations of a
radionuclide occurring in unit time. The SI unit of activity is the Becquerel (Bq),
which is equal to one nuclear transformation per second. (See also Curie)
Acute - having a short and relatively severe course. A “short term” event or
exposure. (See also chronic)
Adequate protection - protection against ionising radiations so that the radiation
doses received by any person from external and/or internal sources are; as low as
reasonably achievable (ALARA principle), and do not exceed the dose maxima
referred to in section 4, AS2243.3.
ALARA - A basic tenet of radiation protection according to the ICRP. It states
that exposures to ionising radiation must be As Low As Reasonably Achievable.
Alpha decay - emission of two protons plus two neutrons by a larger nucleus.
The emitted foursome is called an alpha particle and causes a decrease in the
*nucleon number of 4 and a decrease in the *atomic number of 2. (See also alpha
radiation)
Alpha particle - a helium-4 nucleus emitted by a larger nucleus during the
course of a radioactive decay known as *alpha decay.
Alpha radiation - a stream of alpha particles.
Annual limit on intake (ALI) - the activity of a radionuclide and any of its
daughters which, if taken alone, would irradiate a person to the appropriate dose
limit for either occupational or member of the public exposure as specified in
Table 4.1 AS2243.3
Becquerel (Bq) - the SI name for the unit of activity; equal to 1 disintegration
per second. (1dps)
The becquerel (Bq) replaces the Curie (Ci) which was defined as the activity of a
radionuclide disintegrating at the rate of 3.7 x 1010 disintegrations per second.
Thus 1 Ci = 3.7 x 1010 Bq and conversely 1 Bq = 2.7 x 10-11 Ci = 27 pCi.
149
Beta particle - a negatively charged particle emitted from the nucleus of an
atom, during the conversion of a neutron to a proton (beta decay). Beta particles
produce ionisation by interacting with electrons in atomic or molecular orbits.
They have a range higher than alpha rays and lower than gamma rays.
Commonly used radionuclides, 3H, 35S, 32P, 45Ca, 47Ca, 60Co, and 137Cs emit beta
radiation. (See also “Bremsstrahlung” radiation).
Beta radiation - a stream of beta particles.
Bremsstrahlung ( German “braking radiation”) - The X- Rays emitted when a
charged particle, especially a fast electron, is rapidly slowed down, as when it
passes through the electric field surrounding an atomic nucleus. The X- Rays
cover a continuous range of wavelengths, which depend on the energy of the
incident particles.
Chronic - persisting over a long period of time. A “long term” event or
exposure.(See also acute).
Committed effective dose - the effective dose that will be accumulated during
the 50 years following the time of intake of radioactive material into the body.
Compound (molecule) - A group of atoms that are joined by chemical bonds.
e.g. Water
150
Electron capture - a radioactive transformation in which a nucleus acquires an
electron from an inner orbit of the atom, thereby transforming initially into a
nucleus with the same mass but atomic number one less than that of the original
nucleus ( ie a proton is transformed into a neutron). This type of capture is
accompanied by emission of an X-Ray Photon as the vacancy of the inner orbit is
filled by an outer electron.
Electronvolt (eV) -a unit of energy equal to the work done on an electron in
moving it through a potential difference of 1 volt. It is used as a unit of particle
energies. (NOT an SI unit). 1 eV = 1.602 X 10-19 joule.
Equivalent dose (HT) - the product of the absorbed dose (averaged over a tissue
or organ) and the radiation weighting factor (WR) for the radiation under
consideration. The SI unit is the joule per kilogram with the special name Sievert
(Sv). (See also effective dose). HT = WR . D
Equivalent dose enables the magnitude of exposures due to different types of
ionising radiations to be compared directly with one another even though the
biological effects of each type of radiation will vary in terms of severity.
Exposure - a measure of the X or gamma radiation at a certain place based upon
its ability to produce ionisation in air.
External radiation - ionising radiation received by the body from sources
outside the body.
Gamma radiation - a short intense burst of excess energy emitted by an excited
nucleus after; α-decay, β-decay or electron capture. Common radionuclides,
47
Ca, 125I, 60Co, 137Cs emit γ-rays. Gamma rays are electromagnetic radiation
with high penetrating power. They have a long range and are less efficient in
producing ionisation than α rays and β rays.
Glove box - a closed box, having impermeable gloves and viewing ports in one
or more sides, which is used to completely enclose radioactive material and
operations on the material.
Gray (Gy) - unit of absorbed dose of ionising radiation equal to 1
joule/kilogram.
Half-life - the period of time in which half the nuclei in a given sample of a
particular radionuclide undergo radioactive decay.
Hereditary effects - biological effects of radiation that are transmitted to
descendants of an irradiated individual as a direct result of damage to the genetic
material within cells.
Internal radiation - ionising radiation received by the body from sources taken
inside the body. Typically this occurs by ingestion, absorption or inhalation of
radioactive material.
Ion - a positively (lost electrons) or negatively charged (gained electrons) entity .
e.g. OH- (hydroxyl ion) or H+ (hydrogen ion).
Ionising radiation - electromagnetic or corpuscular radiation capable of
producing ions directly or indirectly by its passage through matter. It includes
radiations emitted by X-ray tubes and particle accelerators, radioactive materials
and neutrons.
151
Irradiating apparatus - apparatus that is capable of producing ionising
radiation, or of accelerating atomic particles.
Isotopes - Atoms having the same numbers of protons (i.e. same element) but
differing numbers of neutrons in the nucleus.
Leakage radiation - all radiation except the useful beam coming from within a
protective housing.
Linear energy transfer (LET) - a measure of the density of ionisation in a
particular material along the path of travel of an ionising particle. Ionising
radiations of low LET (X, gamma and beta) have low WR values due to the small
amount of ionisation that they cause in human tissue, compared with higher LET
radiations (neutrons and alpha) which have high WR values. Linear energy
transfer is a function of the energy and velocity of a particular radiation.
Nucleon - a*proton or a * neutron
Neutron radiation - consists of fast or slow moving neutrons which are always
derived from the nucleus of atoms. The neutron has a mass of one and is
electrically neutral. Neutrons cannot produce ions directly. They can transfer
energy to atomic nuclei by billiard ball type collisions and the resulting moving
nuclei can produce ionisation. Neutrons can also get absorbed in atomic nuclei
to produce nuclear reactions emitting γ-rays. Neutrons can induce radioactivity
in surrounding material. Sources of neutrons are Californium-252, α-emitters
mixed with beryllium and nuclear reactors.
Nuclide - a species of atom characterised by the composition of its nucleus, i.e.
by the number of neutrons and protons in its nucleus. (See also isotope).
Positron - a positively charged beta particle emitted from the nucleus. It is the
anti-particle of the electron.
Protective housing - a housing of an x-ray tube or of a sealed source intended to
reduce the leakage radiation to a specified level.
Radiation - a stream of particles ( alpha or beta) from a radioactive source. Also
a stream of energy travelling in the form of electromagnetic waves or photons
(eg X - or gamma-rays).
Radiation damage - harmful changes that occur to living organisms as a result
of exposure to energetic electrons, nucleons, fission fragments or high energy
electromagnetic radiation. Damage may be caused by electronic excitation,
ionisation, transmutation or displacement of atoms. These mechanisms may
cause damage to cells: alter their genetic structure, interfere with their division or
kill them. These changes can lead to radiation sickness or radiation burns (from
large doses of radiation).
Radiation laboratory - a laboratory in which irradiating apparatus or sealed
radioactive sources are used or stored. It does not contain any unsealed
radioactive material.
Radiation Weighting Factor (WR) - a non-dimensional weighting factor used in
radiation protection to weight the absorbed dose. It depends on the type and
energy of the radiation incident upon the body.
152
Radiation worker - a person who, in the course of his/her employment, may be
exposed to ionising radiation arising from his/her direct involvement with
sources of such radiation.
Radical (free) - an atomic or molecular entity missing a single electron from an
outer shell.
Radioactive contamination - the presence of a radioactive substance or
substances in or on a material or on a place where it is undesirable or could be
harmful. In the specific case of the human body, this contamination includes
both external skin contamination and internal contamination.
Radioactive material - any substance that consists of, or contains any
radionuclide, provided that the activity of such material is greater than 70 Bq/g,
or such other value defined in relevant legislation.
Radioisotope - an isotope that is radioactive.
Radioisotope laboratory - a laboratory in which unsealed radioactive material is
used or stored. It does not contain any irradiating apparatus.
Radiological hazard - the potential danger to health arising from exposure to
ionising radiation; it may arise from external radiation or from radiation from
radioactive materials within the body.
Radiological laboratory - a laboratory which incorporates the functions of both
a radiation laboratory and a radioisotope laboratory.
Radionuclide - a species of atom which undergoes spontaneous nuclear
transformation with the emission of corpuscular or electromagnetic radiations.
Radiotoxicity - the toxicity attributable to ionising radiation emitted by a
radionuclide (and its decay products) incorporated in the human body;
radiotoxicity is related not only to the radioactive characteristics of the
radionuclide but also to its chemical and physical state and to the metabolism of
the radioactive elements in the body or in an organ of the body.
Sealed source - any radioactive material that is firmly bonded within metals or
sealed in a capsule or similar container of adequate mechanical strength so as to
prevent dispersion of the active material into the surroundings under foreseeable
conditions of use and wear.
Shell - an orbit around the nucleus of an atom at a certain energy level. It will
be inhabited by one or more electrons.
Sievert (Sv) - the name of the SI unit of equivalent dose or effective dose it is
equal to 1 joule/kilogram..
Somatic effects - biological effects of radiation observed in an individual who
has been irradiated with large acute doses.
Stochastic effects - effects on a biological system in which the probability of an
effect rather than its severity is regarded as a function of dose, without a dose
threshold. The only examples are carcinogenesis and benign tumours in exposed
individuals and hereditary effects in the descendants of exposed individuals.
Tissue weighting factor (WT) - a non-dimensional factor used in radiation
protection to weight the equivalent dose. It represents the relative contribution of
each tissue or organ to the total detriment due to stochastic effects resulting from
153
uniform irradiation of the whole body. (Tissue weighting factors are given in
table A2, AS2243.4)
Unsealed source - a source which is not a sealed source and which under normal
conditions of use can produce contamination.
Useful beam - that part of the primary and secondary radiation which passes
through the aperture, cone or other device for collimating a beam of ionising
radiation.
X-radiation - produced by bombarding atoms with high energy particles (eg
electrons). All atoms emit a characteristic X- ray spectrum. X- rays are emitted
when the incident electrons knock out an inner orbital electron and an outer
orbital electron falls in to replace it, losing energy as it does so. (See also
Bremsstrahlung).
154
Appendix A
155
MANUAL FOR USERS OF IONISING RADIATION ........................................................................
1. INTRODUCTION .......................................................................................................................................
2. RESPONSIBILITY FOR IONISING RADIATION SAFETY AT MONASH UNIVERSITY........................................
3. TYPES OF IONISING RADIATION ..............................................................................................................
4. THE INTERACTION OF IONISING RADIATION WITH BIOLOGICAL MATTER .................................................
5. THE RELATIVE EFFECTS OF SPECIFIC RADIATIONS ON THE BODY ...........................................................
6. SUSCEPTIBILITY TO THE EFFECTS OF IONISING RADIATION BY DIFFERENT BODILY TISSUES ...................
7. THE BIOLOGICAL EFFECTS OF IONISING RADIATION ................................................................................
7.2. The Effects of Ionising Radiation on the Human Body ..................................................................
8. SOURCES OF EXPOSURE TO IONISING RADIATION AT MONASH UNIVERSITY ...........................................
8.1. MAN MADE SOURCES OF IONISING RADIATION ...................................................................................
8.2. Natural Sources of Ionising Radiation ...........................................................................................
9. THE LEVEL OF RISK IN RELATION TO THE USE OF IONISING RADIATION ...................................................
10. STATUTORY REQUIREMENTS .................................................................................................................
11. EXPOSURE TO IONISING RADIATION ......................................................................................................
11.1. INTERNAL EXPOSURE.........................................................................................................................
11.2. External Exposure ........................................................................................................................
12. MONITORING FOR IONISING RADIATION ................................................................................................
12.1. Introduction ..................................................................................................................................
12.2. Types of monitoring......................................................................................................................
12.3. Types of Instruments for Measuring Ionising Radiation ..............................................................
13. LIMITS OF ACCEPTABLE EXPOSURE .......................................................................................................
13.1. The ICRP dose limits ....................................................................................................................
13.2. Monash University Action Limits .................................................................................................
14. CONTROL MEASURES FOR IONISING RADIATION ....................................................................................
14.1. Preferred Control Measures ........................................................................................................
14.2. Personal Protective Equipment ....................................................................................................
14.3. Control Measures Specifically for External Radiation Hazards ..................................................
14.4. Control Measures Internal Radiation Hazards ............................................................................
15. DISPOSAL OF RADIOACTIVE WASTE ......................................................................................................
15.1. Segregation of Waste....................................................................................................................
15.2. Packaging of Waste for Disposal ................................................................................................
15.3. Labelling of Waste for Disposal ...................................................................................................
16. INCIDENTS INVOLVING IONISING RADIATION ........................................................................................
16.1. Definition of an Incident ..............................................................................................................
16.2. Emergency Procedure ..................................................................................................................
16.3. Rules for Decontamination...........................................................................................................
17. THE RADIOISOTOPE LABORATORY .......................................................................................................
17.1. Grading of laboratories ...............................................................................................................
17.2. Radioisotope laboratory requirements .........................................................................................
17.3. Radioisotope laboratory practices ...............................................................................................
17.4. Contamination and decontamination ............................................................................................
17.5. Common laboratory radioisotopes ...............................................................................................
17.6. Monitoring ....................................................................................................................................
156
MANUAL FOR USERS OF IONISING RADIATION
1. Introduction
The Manual for Users of Ionising Radiation is intended for use by radiation workers. It
should be read in conjunction with the Monash University Ionising Radiation Policy
Statement.
All individuals within a department that uses or stores ionising radiation are required to
behave in a responsible manner and to obey safety instructions.
• Particulate Radiation
Alpha radiation
Beta radiation
Particles consisting of fast moving very low mass electrons with a single negative
charge. In general beta particles travel a few metres in air and a few centimetres in
tissue. They have a range higher than most alpha particles and lower than most
gamma rays. Some examples of beta emitting nuclides are; carbon-14, tritium
(hydrogen-3), sulphur-35, calcium-45, phosphorous-32, and strontium-90.
Neutron radiation
Neutral, particulate radiation with a mass the same as a proton. In human tissue the
average distance of penetration varies from 0.6 centimetres to nearly 10 centimetres
depending on the energy of the neutrons. Californium-252 is an example (sufficient
length of half-life) of an artificially produced radionuclide that spontaneously
undergoes fission and subsequent emission of neutrons.
• Electromagnetic Radiation
157
Gamma radiation
X radiation
X radiation has travel ranges that vary enormously according to energy. It has the
same properties as gamma radiation except that the range of travel distances tends to
be larger. Examples of X ray sources are X ray machines and X ray diffractometers.
• Alpha radiation
Alpha radiation does not present a significant external radiation hazard because it only has a
range of several centimetres in air and is stopped by the outer layers of human skin.
However, if taken inside the body alpha radiation presents the most serious internal radiation
hazard of all because of its propensity for intense ionisation in a local area of tissue.
Nuclei that emit alpha particles are heavy nuclei. The chemical properties of such elements
dictate that they are bone seekers and that they have long biological half lives. Consequently
many alpha emitters have been associated with bone cancer.
• Beta radiation
Beta radiation rarely presents a large external hazard unless it is highly energetic (e.g.
Phosphorous-32) and close to the skin, in which case it may cause injury to the outer layers
of skin. If taken within the body beta radiation represents a significant internal hazard due to
its ability to ionise the tissue in a localised area.
158
• Gamma, X and neutron radiation
Gamma, X and neutron radiation are most serious as external radiation hazards due to their
ability to traverse large distances. They may cause injury to all areas of the body without
much localisation. They do not represent the internal radiation threat that the particulate
radiations do because much of the energy may pass through the body without causing any
damage.
Radiation weighting factors express the relative damaging capability of different kinds of
ionising radiation. The higher the factor the greater the damaging capability of a unit
amount of the radiation.
Different tissues within the body show differing susceptibilities to the effects of ionising
radiation. It is considered that those organs or tissues with the highest tissue weighting
factors have the greatest susceptibility to ionising radiation.
159
7.2. The Effects of Ionising Radiation on the Human Body
• Radiation sickness
• Death
• Cancer
This may occur in almost any organ in the body and its initial location is dependent
on the type of radiation, the isotope and the area of the body that is exposed. The
mechanism of cancer induction is believed to be a direct result of the ionising
potential of radiation. The main examples of cancers that may be induced by
exposure to ionising radiation are shown below.
160
• The Skin
Ionising radiation will cause severe reddening of the skin and temporary depilation
after approximately 3-5 Gy as an acute dose. Basal cell and squamous cell
carcinomas, but not melanoma (the most dangerous of all skin cancers), have been
associated with exposure to ionising radiation. It is known that exposures to the
skin in excess of 10 Gy carry a significant excess risk of skin cancer.
The threshold of significant depression on the blood forming process for an acute
dose given to the whole bone marrow is 0.5 Gy. The dose rate threshold for
protracted exposure over many years is something more than 0.4 Gy per year.
• Eyes
The lens of the eye is prone to developing cataracts after irradiation. Neutrons have
been shown to have the greatest damaging ability. The general threshold that is
given to avoid visual impairment in the case of occupational exposures which are
highly fractionated and protracted, is a maximum of 0.15 Sv per year.
The germ cells of both sexes are more highly radiosensitive than other reproductive
cells. All effects of sterility on the germ cells are early, somatic and deterministic.
• The Thyroid
Functional thyroid damage ensues when the whole of the organ is exposed to doses
in excess of 25-30 Gy fractionated over 30 days.
The effects of ionising radiation on the unborn child depend almost entirely on the stage of
foetal development. Up to 3 weeks after conception the effect of even a small, acute
radiation exposure (such as 0.1 Gy) may be an undetectable death and purging of the
embryo. Higher doses during later stages of the pregnancy may induce the same effect.
During the third week the period of organogenesis begins. From this time until the end of
major organogenesis at start of the ninth week after conception, the embryo is vulnerable to
malformations in any organ under development at the time of exposure. Such
malformations are estimated to have a threshold of 0.1 Gy in human beings.
Throughout the period commencing 3 weeks after conception and ending at birth the unborn
child may be susceptible to an increased probability of cancers or leukemias that are
expressed in the first decade of life. Estimates of the doses required to increase this
probability are unavailable at this time.
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During this same period the brain of the unborn child seems particularly vulnerable. IQ may
be affected in a direct relationship with increasing dose.
• Irradiating Apparatus
• Sealed Sources
Some examples of the sealed sources held by Monash University, their activities
and their uses are listed below
Sealed source apparatus contain one or more sealed radioactive sources installed in
a housing which prevents or minimises exposure of the users to the apparatus.
Some of these sources are listed below.
Unsealed sources are not contained in the same manner as a sealed source. They
will readily produce contamination if handled inexpertly. Some of the wide variety
of unsealed radioactive nuclides used at Monash University are listed below.
• Radioactive Fallout
• Cosmic Radiation
Cosmic radiation comes from the sun and its intensity varies with altitude. For
example at Sydney (sea level) exposure due to cosmic radiation is approximately
300 mSv per year.
• Terrestrial Radiation
Exposure from terrestrial radiation comes mainly from the ground and building
materials. Radio isotopes such as potassium-40, uranium-23 and thorium-232 are
common constituents of soils and building materials.
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Isotopes such as these give all people radiation exposures that vary between 200
µSv and 25,000 µSv per annum depending on soil and rock composition in the
geographical area.
Studies have shown that the total risk for the radiation worker population is equal to that for
a non-radiation worker population which had a fatal accident rate of 35 - 50 x 10-6 per year.
In other words, the 2 mSv of occupational exposure to ionising radiation encountered by
radiation workers had added between 10 and 25 fatalities per million radiation workers at
risk. This fatality rate is still less than many non-radiation industries: e.g.
Monash University follows the directives of the Victorian State Government in relation to
ionising radiation. Many recommendations of the NH&MRC and Standards Australia are
also followed.
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11. Exposure to ionising radiation
Internal exposure to ionising radiation comes about as a result of irradiation of inner body
tissues resulting from surface or airborne contamination which has come into contact with
and entered the body. The order of significance of each form of radiation as an internal
hazard is as follows:
α increasing
β ↑ internal
γ hazard
neutrons
It is the inadvertent release of unsealed sources (contamination) that poses the main threat as
an internal radiation hazard. Such contamination may easily become incorporated in organs
or tissues if it is not carefully controlled.
External exposure to ionising radiation arises from sources outside the body. Sealed and
unsealed sources and irradiating apparatus may all become external radiation hazards if not
handled properly. The order of significance of each form of radiation as an external hazard
is as follows:
α increasing
β ↓ external
γ hazard
neutrons
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12. Monitoring for ionising radiation
12.1. Introduction
• Personal monitoring (monitor worn on the person) for the purposes of assessing
the equivalent dose to the whole body or extremities.
The whole body external exposure is measured using a film badge or a thermoluminescent
dosimeter which is worn by the individual on the waist. Those who use neutron moisture
meters should wear personal neutron radiation monitors.
The normal period of wearing for a whole body TLD is 8-12 weeks, except for pregnant
women in which case it is 4 weeks. All persons working with ionising radiation (i.e.
radiation workers), at the University will be required to wear personal monitoring devices.
Work in close proximity to radiation sources of small dimensions or with devices producing
narrow beams of radiation, may expose a part of the body, particularly the fingers to high
doses. "Finger TLD" dosimeters must be worn by staff working with phosphorus-32
unsealed source or x-ray diffraction x-ray fluorescence apparatus.
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12.2.2. Internal Dosimetry
Thyroid monitoring
Monash University requires that all persons using radioactive iodine undergo regular thyroid
monitoring every six months at least. If radioactive iodine is being used regularly,
monitoring must be done monthly and immediately following any major task using the
isotope. In the case of persons irregularly using radioiodine, thyroid monitoring should be
done after each round of radioiodine manipulation.
Bioassay
Urine monitoring for tritium and carbon-14 beta emitters is the only bioassay monitoring
commonly done at Monash University.
12.2.3. Area
Contamination on surfaces
Because both alpha particles and low-energy beta particles have very limited ranges in air,
the detector must be held very close to, but not actually touching, the surface under
investigation.
If inferences are to be made about dose using a count rate meter, then the meter must be
calibrated in such a way that count rate can be related quantitatively to dose rate.
Wipe or smear testing should be used when direct monitoring is inappropriate. Examples of
such situations are when monitoring for low energy beta emitting surface contamination
(e.g. tritium or carbon-14), or the degree of removable contamination is to be estimated.
The procedure for wipe or smear testing should be discussed with your RSO or Deputy
RSO. In brief, it involves wiping contamination onto a filter paper, counting the paper and
comparing the result against the standard for surface contamination; the "derived working
limit".
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12.3. Types of Instruments for Measuring Ionising Radiation
You should become familiar with the monitoring instruments used by your laboratory. In
brief, the various types are:
These give a readout in counts per unit time. Note that count rate is not the same as activity.
They are usually instantaneous readout instruments.
These give a readout in dose units (Sievert or Gray) per unit time. They work on the same
basic mechanisms as count rate meters except that they sometimes include provision for
distinguishing between different types of radiation. e.g. A sliding plastic plate across the
detector to distinguish between alpha and beta radiation. They are instantaneous readout
instruments.
A supplementary limit applies to protect the unborn child as a dose to the uterus can be taken
to be the whole body dose to the embryo or foetus. This is an effective dose limit of 2mSv
for the abdominal area for the remainder of the pregnancy.
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13.2. Monash University Action Limits
The RPO has imposed action limits on external radiation exposures to university personnel.
These action limits are also part of Monash University’s Ionising Radiation Policy. The
action limits are set at 10% of each ICRP dose limit. Any exposure above the action limit
must be followed up by the RPO in association with the RSO or deputy RSO and the
individual concerned, and a major incident form completed.
Removal
The most desirable option is to use an alternative to ionising radiation where possible.
Substitution
The last resort in preventing personal contamination and external exposure should be the use
of personal protective equipment. Examples of personal protective equipment include:
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14.3. Control Measures Specifically for External Radiation Hazards
Time
Consequently time spent in an area where significant exposure may occur must be kept to a
minimum.
Distance
Dose rate from gamma source is given by an inverse square law. In general people should
stay as far away from radiation sources as possible.
Shielding
• Alpha radiation
Alpha radiation does not require shielding due to its extremely low penetrating
capability. It will be stopped by a sheet of paper, a few centimetres of air or the outer
layer of human skin.
• Beta radiation
For shielding beta radiation, low atomic number material (e.g. perspex, aluminium) is
preferable to minimise the production of bremsstrahlung. Generally 10 mm of
perspex will shield the most powerful beta emitters
(1-10 MeV range) and stop the formation of bremsstrahlung. Several millimetres of
aluminium will afford the same attenuation.
For shielding gamma and X radiation, high atomic number material (dense) is often
used (e.g. lead, depleted uranium or tungsten). Lower atomic number material (e.g.
steel, concrete or water) can be used but in correspondingly greater thicknesses.
• Neutrons
Sometimes boron or cadmium are added to shielding materials as these elements have
particular properties that make them good at attenuating neutrons. e.g. The boron
rods used to control nuclear reactors.
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• Multiple source shielding requirements
The most common situation requiring shielding of two different types of radiation is
when beta and gamma isotopes are being used or stored together. In this case it is
prudent to use a shield for the beta radiation closest to the sources (i.e. perspex or
aluminium) and this should be followed by a shield suited to gamma radiation (e.g.
lead). Note that a reversal in the order of theses shielding materials in relation to the
source may lead to the generation of bremsstrahlung radiation.
A system of "primary" and "secondary" containment should be put around any source
of ionising radiation that is liable to cause contamination. Use items of primary
containment immediately around the source e.g. Benchcoat, floorcoat, trays and
sumps. Use secondary containment around the primary containment e.g. Smooth
surfaces, fumehoods and glove boxes.
The cleanliness of a work area must be of the highest standard. As routine practice
the work area should be checked for contamination before and after any work
procedure and in any case, at least once per day.
Adopt a policy of using the smallest amount of the least toxic isotope that is suitable
for the task.
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15. Disposal of radioactive waste
All radioactive waste must be double bagged and one of the layers shall be waterproof.
Solid waste intended for landfill should be packed into closed drums, multiple opaque
plastic bags or multi-layer paper and plastic bags. All container types except metal and
large glass bottles are suitable for incineration.
Syringe needles, pipette tips and any other sharp objects should be packed in closed,
approved sharps containers so that they will not protrude from the packaging.
Animal carcasses or any putrefiable waste must be double bagged as for solid waste and
stored in a freezer until disposal.
Scintillation vials must be collected in closeable plastic 20 litre drums within the
laboratory.
As long as the outer dose rate limit of 5 µSv/hr has been met there is no legal requirement
to label the outside of the package indicating that it is radioactive. It is considered
undesirable to do so. However the inner packaging that is not visible must be labelled as
radioactive.
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All waste containers of radioactive material placed within the radiaoactive stores must be
labelled with a perishable paper label showing the following details. Waste not labelled in
this manner shall not be cleared by the RPO for removal.
Exposure to personnel above the Monash University action levels for ionising
radiation dose.
Any factor that causes damage to a room (or its contents) in which a source of
ionising radiation is located.
The procedure for a radiation worker dealing with an emergency involving ionising
radiation is as follows. It is the responsibility of the first able bodied person on the scene to
initiate the procedure.
3. Notify one of the following persons in order of priority. It then becomes the
responsibility of this person to take charge of the emergency. The most suitable
person to take care of the emergency is usually the RSO, deputy RSO or the RPO.
The RPO must be called in any incident that is assessed as "serious", "significant"
or "lost time" (in accordance with the policy on incident reporting, investigating and
recording), by those first at the scene.
· Immediate supervisor
· The RSO
· The Deputy RSO
· The Safety Officer
· The RPO
· The Resources Manager
· The Head of Department
4. The victim of the incident or the person who first reported it is responsible for
recording the incident in accordance with section 19.7 of this manual.
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17. The Radioisotope Laboratory
The hazard potential of a radionuclide depends on its radiotoxicity class, its activity, its
chemical state and the laboratory manipulations undertaken. As the hazard potential
increases so there is a parallel increase in the requirements for fittings and finish in the
laboratory to maintain a safe work environment.
Three grades of laboratory - low, medium, and high level - have been defined for the use of
unsealed radionuclide sources. Classification procedures are defined in AS 2243.4
(Standards Australia 1994a).
For low-level laboratories, the work involves small quantities of radioactive material; few
modifications are necessary in any modern conventional chemical laboratory. As always, a
high degree of cleanliness is essential and suitable fittings and finish should be chosen. If
practicable, the work should be confined to one or more suitably labelled benches set aside
for radioactive work.
Horizontal surfaces should be covered with non-porous material. Floors should have
smooth, continuous, non-absorbent surfaces - welded vinyl sheet is satisfactory. Tiles are
not satisfactory as they shrink and leave gaps. Floors should never be cleaned by dry
sweeping but by a wet process which minimises airborne dust. Walls and ceilings should
have a non-porous washable surface such as high-gloss paint. Other surfaces liable to
contamination should also be treated so as to give a satisfactory impervious finish.
Detailed requirements for a low level laboratory are given in AS 2243.4 (Standards
Australia 1994a).
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17.2.2. Medium-level laboratory
As set out in AS2243.4 (Int) 1994, medium-level laboratories shall be dedicated solely to
radioisotope work. A typical procedure to be carried out in a medium-level laboratory is
radio-iodination. The allowable activity of 125I may be up to 200 MBq. The requirements
for a medium-level laboratory are more stringent than for a low-level area. These
requirements are detailed in Section 11.6.2., AS2243.4 (Int) 1994.
The high-level laboratory must provide the requirements for low and medium levels plus
additional requirements given in AS 2243.4 (Standards Australia 1994a).
17.3.1. Shielding
The shielding requirements from beta and gamma emitters are summarised in
table 1. functional shielding should be used during storage of the radionuclide and during
its use in the laboratory.
Shielding for storage sites should totally enclose the source (i.e. interlocking walls, top and
base). This is particularly necessary for harder gamma sources where photons could
penetrate the laboratory’s wall, floor or ceiling to produce fugitive exposure outside the
laboratory.
Beta Perspex
Beta + gamma Laminate of perspex (nearest
source) + lead
Gamma, x-ray, Bremsstrahlung Lead, steel, concrete
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impervious surface of the laboratory bench. Porous surfaces (such as an untreated wooden
bench) are not suitable for radiation work.
Any spilt material must be removed immediately it occurs. Failure to do this may result in
further, and more serious, accidents. Tissues used for the clean-up should be held in
sponge forceps to avoid contamination of the hands and must be placed in the radioactive-
waste bin.
Stainless-steel or plastic trays provide an additional means of containment and all the
radioactive manipulations should be carried out inside them. An initial light application of
silicone polish or wax is recommended for reducing the penetration of spilled material into
the surface of the tray. If there is a danger of dust hazard when the spilled radioactive
material dries, the tray should be lined with plastic backed absorbent bench liner. The
paper should be discarded as radioactive waste at the end of each experiment.
Depending on the chemical form of the contaminant and the nature of the surface, surface
decontamination can be achieved with solutions of detergent, ammonium citrate, dilute
dydrochloric acid or kerosene. Be very careful not to spread the contamination.
A medium-level laboratory must have a complete and exclusive set of apparatus always
kept there. Carrier-free isotopes are very likely to become strongly adsorbed on to
glassware, and it is frequently difficult or impossible to remove them. For this reason
disposable plastic apparatus is strongly recommended, if its use is practicable. It is most
important that disposable apparatus should be washed thoroughly before it is placed in the
radioactive-waste bin.
Contaminated glassware must not be returned to the general laboratory glassware but
should be immediately washed in water and then totally immersed in an appropriate
laboratory detergent solution (e.g. R.B.S. 25 or DECON-90). If this habit of immediate
treatment is acquired it will save a great deal of time by preventing radioactive material
from drying on the apparatus and thus becoming much more difficult to remove. Care
should be taken to ensure that radioactive material is not accumulated in the cleaning fluid.
Before being put away, each article which had been contaminated should be tested with a
monitor, though it should be remembered that an external monitor will not detect
contamination inside glassware by substances emitting very soft radiations. If
contamination is still present, the apparatus must be recleaned until an acceptable level of
activity is reached. At this stage, immersion in a solution of carrier - that is, the inactive
form of the radioactive compound one is trying to remove - may be of value.
Each article placed therein should be clearly labelled with the date of contamination, the
isotope and the date on which the radioactivity will have decayed to a safe level.
17.3.4. Sinks
The sink in a radioactive laboratory should be made of stainless steel. The drainage system
from the sink should be continuous, convey the liquid to the main drain and not connected
to open channels or traps.
Before using for washing contaminated glassware, the sink should be carefully cleaned
with a commercial cleansing powder to remove grease. Any traces of radioactive material
released during the washing of glassware, etc. should be flushed away with adequate
amounts of water. A rubber mat should never be used in the bottom of the sink as this
interferes with the free flow of water down the waste pipe and leads to the accumulation of
radioactive material in the sink itself and on the slime which is invariably present on these
mats.
17.3.5. Gloves
The primary purpose of gloves is to prevent contamination of the skin and not to provide
shielding, so thin disposable rubber gloves which allow greater dexterity are always
preferable to thicker gloves.
If the dose of radiation to the hands is an important factor, remote handling methods must
be employed.
Of equal or even greater importance to the wearing of gloves is their removal after the task
is completed and the proper disposal of the gloves to prevent further contamination. The
recommended technique for glove removal follows.
This procedure is such that the inside of the glove is not touched by the outside, nor is any
part of the outside allowed to come in contact with the bare skin.
2. The cuff of each glove should be folded over, outwards, for 4 cm.
3. Put one glove on by grasping only the internal folded-back part with the other hand.
4. Put the second glove on by holding it with the fingers of the gloved hand tucked in
the fold and only touching the outside of the glove.
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7. Gloves should be removed so that they are inside-out after removal, and without
touching the outside surface to either hand or the internal surface of the other glove.
The laboratory should contain separate solid waste bins for contaminated (radioactive)
waste and for general (non-radioactive) waste. The contaminated waste bin must be clearly
labelled and must be of a suitable shielding material (or, in the case of lead shielding, set
inside a suitable shielding material). Disposal of contaminated waste is the responsibility of
the radiation workers.
The lens of the eye is susceptible to damage by radiation. Energetic β emitters (e.g. 32P) are
a particular danger in this regard. The temptation to look into the open neck of a vessel
containing a radioactive substance must be resisted since, under certain circumstances, the
radiation is canalised by the shape of the vessel. If it is essential to see into the vessel, a
mirror should be used and, if necessary, the illumination increased.
In work with β sources, a tall shield of transparent plastic is recommended. The design
should be such as to give shielding protection to the eyes, face and body (as well as clear
vision in every direction). For β sources, the shield is made of 10 mm thick perspex or
acrylic which totally stops betas.
For very low energy γ sources (e.g. 125I), similar transparent screens are available in Pb-
impregnated acrylic. The acrylic is 12 mm thick and has a lead equivalency of 0.5 mm.
For 125I such a screen provides 103 x attenuation of the 0.035 MeV gammas. Note that the
attenuation of such screens is poor for higher energy gammas.
When it is necessary to evaporate a solution (and this should be avoided if possible), the
solution should be placed in a closed system fitted with a condenser or in a rotary vacuum
evaporator. If time permits, freeze-drying is probably the best method for concentrating a
radioactive solution. Evaporation in an open system, if this is unavoidable, must be done in
a fume cupboard and should be conducted at the lowest possible temperature on a water
bath fitted with ceramic rings (for easy decontamination). Infra-red heating from above is
preferable as a means of reducing the spread of contamination during evaporation
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Radioactive solutions frequently come in rubber-capped bottles and the liquid is most
conveniently removed (under sterile conditions if necessary) by means of a disposable
syringe fitted with a long No. 0 hypodermic needle. Remember to insert a second needle
for air balance as the solution is removed.
If sealed glass ampoules have to be opened and the absorbed dose rate at the surface is
high, specialist advice should be sought.
Tests should be carried out to show (by use of a TLD finger badge) that the skin of the
hands receives considerably less than the maximum permissible dose of radiation during
these procedures.
The transfer of aqueous radioactive solutions may be expediently carried out by means of a
Pasteur pipette fitted with a thick-walled rubber teat. Solutions in volatile solvents are not
so easy to handle by this method.
The pipette should never be filled so that the liquid reaches the part held by the fingers, and
the initial pressure on the teat should be such that it is not necessary to continue to
compress it in order to prevent the liquid being sucked into the upper part of the pipette or
even into the teat. One or two preliminary attempts at filling should be made to enable one
to judge the compression required. As an additional precaution it is advisable to suck up a
small quantity of air into the end of the pipette.
After use, the rubber teat, which should not be contaminated, may be removed and
immersed in water containing a little carrier. The pipettes should be wrapped in absorbent
paper and discarded into the contaminated-waste bin or, if necessary, stored.
In order to avoid the danger of ingestion of radioactive material, a rubber teat should never
be moistened with saliva to make it slip on to the pipette easily.
Apart from the ease with which radioactive solutions may be transferred with these
pipettes, the method has the outstanding advantage of speed. If operations of this type are
carried out quickly, the personal exposure is correspondingly reduced.
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Liquid spills on a well-polished and scrupulously clean surface may often be completely
retrieved with one of these pipettes.
The responsibility for cleaning radiochemical laboratories must rest with the radiation
workers. For low level laboratories (and medium level, under most circumstances), it is
reasonable for untrained persons to clean under careful supervision provided that no
radioactive experiments are in progress and the working surfaces are free of contamination.
Once again it is emphasised that ‘wet’ methods of cleaning must be used to minimise the
generation of airborne contaminants.
Radiation work with animals produces some additional concerns, including the generation
of contaminated dust. The following guidelines are provided:
• If possible a room or rooms should be set aside for radioactive animals. Ideally, the
rooms should be arranged as a suite, with access from the main animal quarters.
• Short-term experiments with a small number of animals may be better undertaken in the
radioisotope laboratory where the work can be conducted in a fume cupboard.
• Experiments should be planned to give a graduation of activity from one room to the
next.
• The floor surface must be such that it can easily be decontaminated by hosing down;
this must be done carefully and thoroughly in the radioactive rooms.
• All the waste materials associated with the experiments (faeces, bedding, carcasses, etc.)
must be treated as radioactive and be disposed of accordingly. Metabolism cages which
allow all the waste and droppings to be collected must be used and enough sawdust
should be provided to absorb all the urine. Cages will have to be decontaminated after
use and a lining of polyethylene on the base may simplify this procedure.
• Accidental contamination of animal workers may occur in several ways. For example,
an animal may urinate while being handled, a scratch would may be inflicted and the
skin of the animal (or the bars of the cage) may be contaminated. The strict code of
personal hygiene, gloves and laboratory coat (routinely used in the radioisotope
laboratory) must be maintained.
181
Safe and reasonable limits for the total quantity of radioactive materials in animals at any
one time depend very much on the facilities available and on the experience, training and
degree of supervision of animals handlers. Specialist advice should be sought for
experiments involving more than 1 GBq 3H, 10 MBq of most other isotopes, and any work
with α sources.
182
None of these instruments is a linear device and therefore the exact relationship between
counts s-1 and activity depends on the isotope being measured. It is therefore strongly
recommended that all contamination monitors be calibrated for each isotope being used in
the laboratory. In most instances this can be done by holding the monitor at a known
distance close to but not touching a filter paper which has a known quantity of the isotope
absorbed onto it.
Loosely attached radioactive material on the bench top and floor may be detected using the
smear test. This consists of wiping a known area of the bench with a filter paper (with
known smaller area) and monitoring the filter paper. Some authorities suggest that the
paper should be damp or lightly oiled. If loosely held radioactive material can be removed
in this way, the spread of the contamination may result if it is left without further
treatment. Every effort should be made to eliminate it so that the activity on the filter paper
is finally zero.
If persistent firmly attached activity exceeding the maximum figures in table 2 still remains
on the bench top or floor, that part on which it is localised should not be used during the
decay of the isotope. If the isotope is long-lived its permanent presence is intolerable and
the affected area should either be removed or else covered with a screening material such as
lead or concrete.
Tritium is a pure β emitter, maximum energy 0.018 MeV. The very low energy β particle
has a range of only mm in air. Hence there is no need for shielding for external radiation.
This extremely short range makes it almost impossible to monitor for tritium using
conventional instruments. An airflow monitor which sucks in air is available for measuring
airborne 3H contamination. Surface contamination can be indicated by a wipe test or
measured using a special ‘windowless’ monitor. Internal burdens are assessed by liquid
scintillation counting of urine samples.
Tritium is a moderate radiotoxic nuclide (group 3), with effective half life in the body of 10
days. However, ingested 3H in certain forms is a much greater biological hazard than
tritiated water. Tritiated nucleosides (and to a lesser extent simpler organic molecules) may
be incorporated into the DNA of actively metabolising cells, causing an increased genetic
hazard for three reasons:
• the low energy of the β emission means a very short range and ensures that all the
radiation energy from a decay is deposited very close to that DNA; and
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• actively metabolising cells are generally more radiosensitive than non-dividing cells.
From the point of view of ingestion hazard, tritiated nucleosides are approximately ten
times more harmful than tritium in an inorganic form.
17.5.2. Carbon-14
Carbon-14 is a pure β emitter, maximum energy 0.156 MeV. The low energy β particles
have a range of 25cm in air and are stopped by the outer skin layer. Hence, there is no need
for shielding for external radiation.
14
C is detected by a number of counter types. 14C is a nuclide of moderate radiotoxicity
(group 3), with effective half-life in the body of 40 days. Carbon-14, like tritium, when in
certain organic forms may be selectively concentrated in cellular DNA. The radiotoxicity
of such compounds will be approximately ten times more harmful than 14C in an inorganic
form.
17.5.3. Phosphorus-32
Phosphorus-32 is a pure β emitter, maximum energy 1.71 MeV. This hard β emission has a
7-m range in air and represents a significant external radiation hazard.
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17.5.4. Sulphur-35
Sulphur-35 is a pure β emitter, maximum energy 0.167 MeV. The shielding and detection
requirements are thus similar to those of 14C.
The low-energy β particles from 35S have a range of 30 cm in air and are stopped by the
outer skin layer. Hence, there is no need for shielding for external radiation.
35
S is a nuclide of moderate radiotoxicity (group 3), with effective half-life in the body of
80 days.
17.5.5. Calcium-45
45
Ca has a weak β emission, maximum energy 0.257 MeV. The shielding requirements in
place for 32P are more than adequate for 45Ca.
45
Ca is a nuclide of high radiotoxicity (group 2).
17.5.6. Sodium-22
22
Na emits a medium energy positron (0.55 MeV), a hard γ-ray (1.27 MeV) and two
positron annihilation photons (0.511 MeV) per disintegration. Shielding needs to be
appropriate for the hard γ-ray.
22
Na is a nuclide of high radiotoxicity (group 2), with an effective half-life in the body of 10
days.
For very low energy γ sources like 125I, transparent screens are available in Pb-impregnated
acrylic. The acrylic is 12-mm thick and has a lead equivalency of 0.5 mm. For 125I such a
screen provides 103 x attenuation of the 0.027 MeV gammas. Note that the attenuation of
such screens is poor for higher energy gammas.
Low energy X and γ radiation is only poorly detected by G-M monitors. Appropriate
scintillation detector probes are required for monitoring.
131
I emits a medium energy β (maximum energy 0.61 MeV) and a range of γ ray energies
(majority 0.36 MeV, small percentage of 0.72 MeV). Shielding for 131I needs to be
appropriate for the highest energy γ emission.
185
Iodine as the free element is quite volatile and strict precautions must be taken to reduce the
risk of inhalation. furthermore, the high capacity of the thyroid to absorb iodine selectively
from the bloodstream results in these isotopes being even more hazardous biologically than
their physical properties would appear to indicate. Both 125I and 131I are nuclides of high
radiotoxicity (group 2), with an effective half-life in the body of 35 days for 125I and 7 days
for 131I.
17.5.8. Strontium-90
Strontium-90 is one of the most radiotoxic of the elements of low atomic number because it
can substitute for calcium in bone producing a long effective half-life in the body. 90Sr has
a very high radiotoxicity (group 1) grading and an effective half-life in the body of 18
years.
Specialist advice must be sought before the use of this isotope is contemplated.
These elements are all in the very high or high-toxicity category. They are difficult to
monitor and great care must be taken to prevent inhalation. Approval for the use of α
emitters is only granted subject to the most stringent conditions of safety and disposal.
17.6. Monitoring
186
Appendix B
Statutory Documentation for Ionising Radiation
• Code of Practice for the Safe Use of Radioactive Luminous Compounds (1971)
• Recommendations for exemptions from Licensing of Gaseous Tritium Light Devices (1975)
No. 2. Code of Practice for the Design of Laboratories Using Radioactive Substances for
Medical Purposes (1980)
No. 3. Code of Practice for the Safe Use of Ionizing Radiation in Veterinary Radiology:
Part 1 and 2 (1982)
No. 4. Code of Practice for the Safe Use of Radiation Gauges (1982)
No. 8. Code of Nursing Practice for Staff Exposed to Ionizing Radiation (1984)
No. 9. Code of Practice for Protection Against Ionizing Radiation Emitted from X-Ray
Analysis Equipment (1984)
No. 10. Code of Practice for the Safe Use of Ionizing Radiation in Veterinary Radiology:
Part 3 - Radiotherapy (1984)
No. 11. Code of Practice for the Safe Use of Soil Density and Moisture Gauges Containing
Radioactive Sources (1984)
No. 12. Administration of Ionizing Radiation to Human Subjects in Medical Research (1984)
No. 13. Code of Practice for the Disposal of Radioactive Wastes by the User (1985)
No. 18. Code of Practice for the Safe Handling of Corpses Containing Radioactive materials
(1986)
No. 22. Statement on Enclosed X-Ray Equipment for Special Applications (1987)
No. 23. Code of Practice for the Control and Safe Handling of Radioactive Sources Used for
Therapeutic Purposes (1988)
187
No. 24. Code of Practice for the Design and Safe Operation of Non-Medical Irradiation
Facilities (1988)
No. 25. Recommendations for Ionization Chamber Smoke Detectors for Commercial and
Industrial Fire Protection Systems (1988)
No. 26. Policy on Stable Iodine Prophylaxis Following Nuclear Reactor Accidents (1989)
No. 28. Code of Practice for the Safe Use of Sealed Radioactive Sources in Borehole Logging
(1989)
No. 31. Code of Practice for the Safe Use of Industrial Radiography Equipment (1989)
No. 33. Interim Statement on Australia's Radiaiton Protection Standards (June 1991)
No. 39. Recommendations for Limiting Exposure to Ionising Radiation (1995) (Guidance
note [NOHSC: 3022 (1995)]) and National Standard for limiting occupational
exposure to ionising radiation [NOHSC: 1013 (1995)]
188
2 AUSTRALIAN STANDARDS
189
Appendix C
SAMPLE CALCULATIONS ON IONISING RADIATION
Information:
Solution:
∴ Curies = 5 x 106 Bq
3.7 x 1010 Bq
Information:
Solution:
∴ n = 24hr
6.01hr
= 3.99 = ~4
At = 40 x 109 Bq
24
= 2.5 GBq
190
3. What is the unshielded dose rate 3 metres from 100 GBq source of 137Cs?
Information:
DR = ΓxA
d2
Solution:
= 933 μSvh-1
4. What thickness of lead shielding would be required to reduce a dose rate of 1867 μSvh-
1
to 25 μSvh-1?
Information:
Solution:
t = 4.05 cm
191
Information:
Use: DR = ΓA
d2
= 0.0185 Gbq
⇒ d = 0.0999 metres
The box will need to be 2d wide, 2d high and 2d long. i.e. 20cm square.
192
6. A Monash department requires a lead lined box for storage of medium term 32P and
125
I waste during its decay.
The annual total amount of these two isotopes that is used within the department
is:
32
P 1μCi
125
I 1μCi
Using the assumption that all of this could end up in the box at once, what thicknesses of
lead and aluminium are required to reduce the dose rate on the outer surface of the box to
0.5 μSvh-1 (in line with the member of the public dose limit of 1 mSv in any single year)?
Assume: The box will be fabricated from 2mm thick steel and it will have
inner layers of lead and aluminium. Aluminium will need to be the inner most
layer in order to avoid the generation of bremsstrahlung radiation. The box will
be essentially full, with only 1mm gap between the packaged waste and any
inner surface.
For 125I:
Information:
0.5 μSvh-1
DRus is the unshielded dose rate at any point 1mm on the inside of the box
surface
DRus = ΓxA
d2
Solution:
∴ DR = 99.9mSvh-1
193
For 32P:
Information:
Instead we know that the effective range of 32P beta radiation in unit
density material is 0.8 cm.
Solution:
0.8 = 0.3 cm
2.702
194
7. Calculate the absorbed dose received by the surface of the body from an
unshielded 1MBq 32P source at a distance of 0.5 m from the source.
Information:
32
P is a pure beta emitter with Umax - 1.71 MeV
A = 1MBq
Umax = 1/81 MeV (AS2243.4, Table A3)
r = 0.5 m
Solution:
= 10 μSvh-1
195