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Syllabus Animal Breeding and Genetics

This syllabus outlines an animal breeding and genetics course that will describe basic genetic concepts, inheritance principles, and genomic techniques. The theory section will cover topics like Mendelian genetics, probability, gene actions, sex determination, mutations, and genetic engineering. Practical sessions include microscopy of cell division, genetics exercises, karyotyping, DNA extraction, PCR, fingerprinting techniques, sequencing, and alignment. Required and recommended textbooks are also listed.

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Zulfiqar Hussan Kuthu
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478 views2 pages

Syllabus Animal Breeding and Genetics

This syllabus outlines an animal breeding and genetics course that will describe basic genetic concepts, inheritance principles, and genomic techniques. The theory section will cover topics like Mendelian genetics, probability, gene actions, sex determination, mutations, and genetic engineering. Practical sessions include microscopy of cell division, genetics exercises, karyotyping, DNA extraction, PCR, fingerprinting techniques, sequencing, and alignment. Required and recommended textbooks are also listed.

Uploaded by

Zulfiqar Hussan Kuthu
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Syllabus/Course Outline

ANIMAL BREEDING AND GENETICS - I 2 (1-1)

Learning outcomes:

At the end of the course, students will be able to:


1. Describe basic concepts of genetics
2. Describe gene as unit of inheritance and principles of inheritance
3. Describe genomic techniques and their application.

Theory:
Genetics; historical development and scope; genetic basis of inheritance, gametogenesis;
Mendelism: Mendel's laws, monohybrid and polyhybrid crosses; Probability: concept and
laws of probability; Chi-square test and its applications; Modified segregation ratios; Multiple
allelomorphism; Polygenic inheritance; Genes and different gene actions: dominance,
recessive, epitasis, additive and non-additive gene action; Genetics of sex: sex determining
mechanisms, sex linkage and its variation; Pleiotropy; Linkage and crossing over; Gene
mutation and chromosomal aberration; Lethal and sub-lethal genes, elimination of lethal
genes from livestock populations and other genetic abnormalities; Genetic engineering: basic
concepts of recombinant DNA technology, gene cloning and manipulation; Its application
and future; Extra-nuclear inheritance.

Practical:
Microscopic studies on the animal cells undergoing mitosis and meiosis; Exercises on
Mendelian and modified segregation ratios; Karyotyping and Banding for detecting
chromosomal abnormalities; Genomic DNA isolation, purification and separation on gel
electrophoresis; Quantification and storage; Primers, Polymerase chain reaction (PCR); DNA
fingerprinting by using restriction fragment length polymorphism (RFLP), random amplified
polymorphic DNA (RAPD), and amplified fragment length polymorphism (AFLP); DNA
sequencing and genotyping; Basic alignment of sequences.
Textbook:
1. Klug, W. S., 2010. Essentials of Genetics. Pearson Benjamin Cummings, San Francisco,
CA.

Recommended Books:
1. Griffiths, A. J. F., 2012. Introduction to Genetic Analysis. W.H. Freeman and Co., New
York.
2. Hodge, R., 2009. Genetic Engineering: Manipulating the Mechanisms of Life. Facts on
File, New York.
3. Gardener, E. J., M. J. Simmons and D. P. Snustad, 1991. Principles of Genetics. John
Wiley and Sons. Inc., New York, U.S.A.
4. Nicholas, F., 2009. Introduction to Veterinary Genetics. Wiley-Blackwell.

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