Ismah Ibtihal

Fadhilah
10718079
Indeks
Drug Therapeutic Level Toxic Level Therapeutic
Index
Acetaminophen 5–20 ug/mL >40 ug/mL 2-8
Alprazolam 10–50 ng/mL >75 ng/mL 1.5-7.5
Amikacin peak: 20–30 ug/mL peak: >35 ug/mL Peak: 1.17-1.75
trough: 4–8 ug/mL trough: >10 ug/mL Trough: 1.25-2.5
Aminocaproic 100–400 ug/mL >400 ug/mL 1-4
acid
Aminophylline 10–20 ug/mL >20 ug/ml 1-2
Amiodarone 0.5–2.5 ug/mL >2.5 ug/mL 1-5
Amitriptyline 120–150 ng/mL >500 ng/ml 3.3-4.17
Amoxapine 200–400 ng/mL >500 ng/mL 1.25-2.5
Atenolol 200–500 ng/mL >500 ng/mL 1-2.5
Aepridil 1–2 ng/mL >2 ng/mL 1-2
HCl
Arbamazepine 5–12 ug/mL >12 ug/mL 1-2.4
Chloral 2–12 ug/mL >20 ug/mL 1.7-10
hydrate
Chloramphenicol 10–20 ug/mL >25 _g/mL 1.25-2.5
Chlordiazepoxide 1–5 ug/mL >5 ug/mL 1-5
Chlorpromazine 50–300 ng/mL >750 ng/mL 2.5-37.51-3.3
Chlorpropramide 75–250 ug/mL >250 ug/mL 1.3-3.3
Cocain 33gram 330 gram 10
Codeine 80 mg 1200 mg 15
Clonazepam 15–60 ng/mL >80 ng/mL 1.3-5.3
Cyclosporine 100–300 ng/mL <85 or >500 ng/mL 5.9
Desipramine 150–300 ng/mL >500 ng/mL 1.7-3.3
Diazepam 0.5–2 mg/L >3 mg/L 1.5-6
Digoxin 0.8–2 ng/mL >2 ng/mL 1-2.5
Diltiazem 50–200 ng/mL >200 ng/mL 1-4
Disopyramide 2–5 ug/mL >7 ug/mL 1.4-3.5
DMT 40 mg 800 mg 20
DXM 40 mg 2000 mg 50
Doxepin 150–300 ng/mL >400 ng/mL 1.3-2.7
Ethosuximide 40–100 ug/mL >150 ug/mL 1.5-3.75
Flecainide 0.2–1 ug/mL >1 ug/mL 1-5
Gentamicin peak: 6–10 ug/mL peak: 12 ug/mL Peak: 1.2-2
trough:<  2 ug/mL trough: > 2 ug/mL Trough:1
Haloperidol 3–20 ng/mL >42 ng/mL 2.1-14
Heroin 8mg 50mg 6.25
Hydromorphone 1–30 ng/mL >100 ng/mL 3.3-100
Imipramine 150–300 ng/mL >500 ng/mL 1.7-3.3
Isobutyl Nitrite 0,2 ml 1.5ml 7.5
Kanamycin 20–25 ug/mL >35 ug/mL 1.4-1.75
Ketamine 70 mg 2700 mg 38.57
Lidocaine 1.5–5 ug/mL >5 ug/mL 1-3.3
Lithium 0.5–1.5 mEq/L >1.5 mEq/L 1-3
LSD 0.1 mg 100mg 1000
 Marijuana 15 mg >15 gram >1000
MDMA 125 mg 2000 mg 16
Meperidine 0.4–0.7 ug/mL >1 ug/mL 1.4-2.5
Mescaline 350 mg 8.4 gram 24
Methadone 5mg 100 mg 20
Methamphetamine 15 mg >150mg >10
Methotrexate _>0.01 umol >10 umol in 24 hr 1000
Mexiletine 0.5–2 ug/mL >2 ug/mL 1-4
Mezlocillin 35–45 ug/mL >45 ug/mL 1-1.3
sodium
Milrinone 150–250 ng/mL >250 ng/mL 1-1.7
Morphine 10–80 ng/mL >200 ng/mL 2.5-20
Nicardipine 0.028–0.05 ug/mL >0.05 ug/mL 1-1.8
Nifedipine 0.025–0.1 ug/mL >0.1 ug/mL 1-4
Nitrous Oxide 3.5 L 525L 150
Nortriptyline 50–150 ng/mL >500 ng/mL 3.3-10
Phenobarbital 15–30 ug/mL >40 ug/mL 1.3-2.7
Phenytoin 10–20 ug/mL >20 ug/mL 1-2
Primidone 5–12 ug/mL >12 ug/mL 1-2.4
Procainamide 4–10 ug/mL >10 ug/mL 1-2.5
Propafenone 0.5–3 ug/mL >3 ug/mL 1-6
Propranolol 50–100 ng/m >150 ng/mL 1.5-3
Prozac 200mg >2 gram >100
Psyocybin 6mg 6 gram 1000
Quinidine 2–5 ug/mL >6 ug/mL 1.2-3
Rohypnol 1 mg 30 mg 30
Salicylate 10–30 mg/dL >35 mg/dL 1.2-3.5
Theophylline 10–20 ug/mL >20 ug/mL 1-2
Tobramycin peak: peak: Peak: 1.2-2
6–10 ug/mL >12  ug/mL Trough: 1
trough: trough:>2
< 2 ug/mL ug/mL
Tocainide 4–10 ug/mL >12 ug/mL 1.2-3
HCl
Trazadone 500–2000 ng/mL >4000 ng/mL 2-8
Valproic 50–100 ug/mL >100 ug/mL 1-2
acid
Vancomycin peak: peak: Peak: 2-4
20–40  ug/mL > 80  ug/mL Trough: 1-2
trough: trough:
5–10  ug/mL >10  ug/mL
Verapamil 0.08–0.3 0.3 1-3.75
ug/mL > ug/mL

Sumber:
Anonim. 2017. Therapeutic and Toxic, Drug Levels.
http://www.medicalestudy.com/therapeutic-toxic-drug-levels/. Diakses 22 Februari
pukul 15.43
Gable, Robert. 2004. Comparison of Acute Lethal Toxicity of Community Abused
Psychoactive Substances Addiction. https://web.cgu.edu/faculty/gabler/drug_toxicity.htm.
Diakses 22 Februari pukul 15.55