Rapidly-acting insulins (insulin analogues)

Short-acting insulin (natural insulin)

Insulin
intermediate-acting insulins
preparations:
Long-acting insulins

Premixed insulins (rapid-acting + intermediate acing)

(short-acting + intermediate-acting)

Hypoglycemic drugs

Insulin secretagogues Insulin sensetizers Others

Sulfonylureas Biguanides Alpha-glucosidase inhibitors

Meglitinids (glinides) Thiazolidinediones Amylin analogues

(TZDs) (glitazones)

Glucagon-like peptide-1 agonists Dual PPAR agonists Sodium/glucose co-transporter-2

(GLP-1 agonists) (glitazar) inhibitors (SGLT-2 inhibitors)

Dipeptidyl peptidase-4 inhibitors

(DPP-4inhibitors)(gliptins)
 Insulin preparations

Rapidly-acting insulins Short-acting insulin

(insulin analogues) (natural insulin)
insulin asparte regular insulin
insulin lispro (soluble insulin)
insulin glulisine

Intermediate-acting insulins Long-acting insulins

(basal insulin)
neutral protamine hagedorn (NPH) insulin glargine
(AKA insulin isophane) insulin detemir

Premixed insulins

Rapidly-acting insulin Short-acting insulin

+ +
Intermediate-acting insulin Intermediate-acting insulin
aspart 30%+ asparte protamine 70% regular insulin 30% + NPH 70%
aspart 50%+ asparte protamine 50% regular insulin 50% + NPH 50%
lispro 25% + lispro protamine 75%
lispro 50% + lispro protamine 50%
 Insulin secretagogues
Glucagon-like peptide-1 agonists Dipeptidyl peptidase-4 inhibitors
Sulfonylureas Meglitinids (glinides)
(GLP-1 agonists) (DPP-4inhibitors)(gliptins)
*first generation: repaglinide *short-acting(twice daily): *short-acting(twice daily):
acetohexamide – chlorpropamide natiglinide exenatide sitagliptin - vildagliptin
carbutamide – tobutamide mitiglinide
*long-acting(once daily): *long-acting(once daily):
tolazamide liraglutide - lixisenatide saxagliptin – linagliptin
*secend generation: *others: gemigliptin - alogliptin
glipizide - gliclazide taspoglutide - albiglutide
glimepiride –
glibenclamide(glyburide)
glybornuride – glyclopyramide
glisoxepide – gliquidone

Insulin sensetizers others

Biguanides Alpha-glucosidase inhibitors

metformin acarbose – miglitol - voglibose

Thiazolidinediones
Amylin analogues
(TZDs) (glitazones)
rosiglitazone – pioglitazone pramlintide
Dual PPAR agonists Sodium/glucose co-transporter-2 inhibitors
(glitazar) (SGLT-2 inhibitors) (gliflozins)
saroglitazar dapagliflozin – canagliflozin
empagliflozin
*soluble insulin (regular insulin)(microcrystalline): -penfill: cartridges (not disposable)
actrapid-hm (penfill-vial-novolet) – humulin-R (vial-penfill) -flexpen: (disposable)
insulinagypt-R (vial) – insulin HbioR (vial) - human insulin-R (vial) -prefpen=prefilled pen (disposable){in case of
insuman rapid (penfill-vial) humalog it is called kwikpen}
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*insulin aspart: -(single): novorapid (penfill-flexpen)
-combination (insulin.aspart-insulin.asparte.protamine): novomix 30 (penfill-flexpen) – novomix 50 (penfill-flexpen)
*insulin lispro: -(single): humalog (penfill-kwikpen)
-combination (insulin.lispro-insulin.lispro.protamine): humalog mix 25(kwikpen-penfill) – humalog mix 50 (kwikpen-penfill)
*insulin glulisine: -(single): apidra (prefilled pen-penfill) – apidra solostat
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*insulin isophan (NPH):
humulin-N (kwikpen-penfill-vial) – insulinagypt-N (vial) –insulatard-hm (penfill-vial-novolet)
insulin HbioNPH (vial) - insuman basal (penfill-vial)
-combination (soluble.insulin-insulin.NPH):
mixtard 30 HM (penfill-vial) – mixtard 50 HM (penfill)
mixtard 10 (novolet) - mixtard 20 (novolet) - mixtard 30 (novolet) - mixtard 40 (novolet) - mixtard 50 (novolet)
insuman comb 30 (vial) – insuman comb 30 (penfill) – insuman comb 50 (penfill) – insuman25/75 (vial)
human insulin mix vacsera (vial)
insulin H mix 70/30 (vial) – insulinagypt 70/30 (vial) - humulin 70/30 (vial-penfill) – hunil mix 70/30 (vial)
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*insulin glargine: lantus (penfill) – lantus optiset (prefpen) – lantus solostar (prefpen)
*insulin detemir: levemir (penfill-flexpen)
*chlorpropamide: pamidin (tab) *tolbutamide: diamol (tab)
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*glipizide: -(single): (tab): minidiab - glipizide - glupizide -combination (glipizide-metformin): engilor (tab)
*gliclazide: (tab): diabetron – diabyl – diamedizen – diamedizen-MR – diamicron – diamicron MR
dianormal – gli SR – gliclazide – glipicrone – semi-glipicron – serviclazide – unocron MR
*glimepiride: (tabs):
-(single): amaryl - conida – diabenor – diabeto – diabride – diabride – dolcyl
glaryl – glimadel – glimaryl – glimitoid – glucoless – glucoryl – glemax – gedimadel – reglidib
-combination (glimepiride-pioglitazone): amaglust – glimepiride plus – zanoglide
(glimepiride-rosiglitazone): avandaryl
(glimepiride-metformin): amaryl-M
*gliquidone: glurenor (tab)
*glibencalmide:(glyburide): (tab)
-(single): daonil – diaben - euglucon – euglumide – glibenase – semi-daonil
-combination (glibenclamide-metformin): diavance – euglumide plus – glime forte – glimet
glucovance – gluokan – glybformin – meburide – metclamide
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*repaglinide: (tab): diarol – novonorm – repaglid – repaglinide - repanidin
*nateglinide: (tab): -(single): starlidine – starlix -combination (metformin-nateflinide): starlix combi (tab)
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*exenatide: (penfill): byetta *liraglutide: (penfill): victoza
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*sitagliptin: (tabs): -(single): glaptivia – januvia -combination (sitagliptin-metformin): glaptivia plus – janumet
*vildagliptin: (tabs): -(single): galvus – gliptus – icandra - vildagluse
-combinations (vidagliptin-metformin): glvus-met – gliptus plus – icandra plus – vildagluse plus
*saxagliptin: (tab) -(single): onglyza -combination (saxagliptin-metformin): kombiglyze XR
*linagliptin: trajenta (tab)
*metformin: (tab):
-(single): alexodiab - amophage - cidophage - cidophage retard - diaformin
diaphage - diaphage XR - maxophage XR - mepaphage - meglocon - diaquit - glucolight XR
-combination
(glimepiride-metformin): amaryl-M
(glipizide-metformin): engilor
(glibenclamide-metformin): amophage extra - diavance - euglumide plus - glime forte - glimet
glucovance - gluokan - glybformin - meburide - metclamide
(metformin-nateglinide): starlix combi (tab)
(sitagliptin-metformin): glaptivia plus - janumet
(vidagliptin-metformin): glvus-met - gliptus - icandra plus - vildagluse plus
(saxagliptin-metformin): kombiglyze XR
(rosiglitasone-metformin): avandamet - avndaryl - rosi plus
(pioglitazone-metformin): bioglita plus - glustacomb - pioglumet

*rosiglitazone: (tab): -(single): avaglit - avandia - diazan - rosandia

-combination (rosiglitazone-metformin): avandamet - avandaryl - rosi plus

*pioglitazone: (tab): -(single): actos - actozone - diabetin - diabetonorm - ensudyne - glustazon - glustin - hi-glitazone - piojet
-combination (glimepiride-pioglitazone): amaglust - glimepiride plus - zanoglide
(pioglitazone-metformin): bioglita plus - glustacomb - pioglumet
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*acarbose: glucobay (tab)
#herbal preparations:
diaglu (cap) – N.A.D (cap) – sylvester (cap)

#sugar sustituants:
*aspartam:
-(single): aspartac (tab) – diet sweet (tab-powder) – diety (tab) – equal (tab) – go.lite (sachets)
smart sweet (tab) – sucram (tab) - sweeter (tab) – sweety (tab)
-combination canderel (tab)(aspartam-lactose-leucine)
diet-on (tab)(aspartam-acesulfame potassium)
go-lite (sachets)(aspartam-sucralose-maltodextrine-dextrose)

*stevia sugar: isi-diet (sachets) – no-cal (sachets) – royal sweet (tab) – splanda (sachets) – stevia (tab) – stevia-MAX (powder)
*sucralose/maltodextrin: dietolose (tab-sachets) – freecal (sachets) – isosweet (sachets) – slimmer (sachets)
*sucrose/sucralose/maltodextrin: sugalite (sachets)
*dextrose/sucralose/maltodextrin: swist (sachets)
*sucrolose/sorbital: sweetal (sachets)
*fruit sugar (fructose): unifructose (powder)
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#preparations for hypoglycemia:

(glucose/vit.C): glucagon (vial) – glucose (chew.tab)