The Nervous System
Organization
Jennifer Carbrey Ph.D.
Department of Cell Biology
Nervous System
Cell types
neurons
glial cells
Methods of communication in
nervous system – between cells
How the nervous system is organized
Nervous System Organization
CNS: spinal cord, PNS: cranial nerves, spinal nerves
brain
afferent neurons are sensory (transmit information to the CNS)
efferent neurons “cause” change (transmit information away from the CNS).
image by Ruth Lawson Otago Polytechnic (modified), Creative Commons Attribution 3.0 Unported license
http://commons.wikimedia.org/wiki/File:Anatomy_and_physiology_of_animals_Relation_btw_sensory,_relay_%26_motor_neurons.jpg,
PNS Sensory Input
Types of sensory input:
Sensory systems: Vision, Hearing, Taste,
Equilibrium, Olfaction, Somatosensation,
(also visceral stimiuli like pH and O2 content of
blood, osmolarity, blood glucose)
Somatosensation receptors in skin, muscle
and bones & visceral receptors (in organs)
detect pain, temperature, touch, pressure,
and proprioception
(joint capsule, tendon, and muscle stretch).
PNS Input & Output
PNS Output
sympathetic NS
CNS organs
acetylcholine, norepi,
nicotinic AChR adrenergic
adrenal gland
CNS epinephrine released into blood organs
acetylcholine, epinephrine,
nicotinic AChR adrenergic
parasympathetic NS
CNS organs
acetylcholine, acetylcholine,
nicotinic AChR muscarinic AChR
somatic NS skeletal
CNS muscle
acetylcholine,
nicotinic AChR
Sympathetic &
Parasympathetic
Nervous systems
image from: Gray, Henry. Anatomy of the Human Body. Philadelphia: Lea & Febiger, 1918;
Bartleby.com, 2000. www.bartleby.com/107/, http://commons.wikimedia.org/wiki/File:Gray839.png,
public domain
Key Concepts
The nervous system is composed of the brain, spinal
cord, cranial nerves and spinal nerves. The first two make
up the CNS, the latter two constitute the PNS.
The CNS and PNS constitute a reflex arc. The CNS (brain
& spinal cord) integrates sensory input (PNS) and
provides appropriate output to effectors (PNS).
The efferent portion of the PNS is divided into somatic
and autonomic nervous systems. Somatic innervates
skeletal muscle to cause contraction. Autonomic nervous
system (ANS) is divided into sympathetic,
parasympathetic and enteric. Sympathetic (SNS) and
parasympathetic act reciprocally and in opposition
(accelerator & brake). Enteric division acts independently
in the gut but can be modulated by the other divisions of
the ANS. SNS is “fight or flight”; ParaSNS is “rest or
digestion”.