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Drug Card: Generic Name: Dimenhydrinate Brand Name: Mechanism of Action

Dimenhydrinate, branded as Dramamine, is an antihistamine used to prevent and treat nausea, vomiting, and vertigo associated with motion sickness. It works by competitively blocking H1 receptors in the bronchial smooth muscle, capillaries, and gastrointestinal tract to prevent histamine-induced effects. The drug is available in injectable and tablet forms for both adults and pediatric patients at a dosage of 50mg. Common side effects include dizziness, nausea, and epigastric distress. It is contraindicated in those with hypersensitivity to the drug.

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353 views1 page

Drug Card: Generic Name: Dimenhydrinate Brand Name: Mechanism of Action

Dimenhydrinate, branded as Dramamine, is an antihistamine used to prevent and treat nausea, vomiting, and vertigo associated with motion sickness. It works by competitively blocking H1 receptors in the bronchial smooth muscle, capillaries, and gastrointestinal tract to prevent histamine-induced effects. The drug is available in injectable and tablet forms for both adults and pediatric patients at a dosage of 50mg. Common side effects include dizziness, nausea, and epigastric distress. It is contraindicated in those with hypersensitivity to the drug.

Uploaded by

sonia suleman
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Drug card

Generic name: Dimenhydrinate


Brand name: Dramamine
Mechanism of Action:
Dimenhydrinate competitively blocks H1 receptors, thereby preventing the actions of histamine
on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents
histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, GI
smooth muscle spasm.
Dosage:
Adults:
Injectable solution
 50mg/mL
Tablet
 50mg

Pediatric:
Injectable solution
 50mg/mL
Tablet
 50mg
Indications:
Dimenhydrinate is indicated for prevention and treatment of nausea, vomiting vertigo of motion
sickness.
Contraindications:
It is contraindicated in conditions like hypersensitivity to drug
Adverse Effect:
 Dizziness
 Epigastric distress
 Anorexia
 Nausea
 Dysuria
 Urinary retention
 Impotence
 Vertigo

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