Questions
) November 25, 2018 ! 0 * 3637
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Q.) Risk factors that
predispose to leukemia
include all EXCEPT
Infectious mononucleosis
Ionizing radiation
Down syndrome
Myelodysplastic syndrome
Q.) The following
statement is TRUE in
acute lymphoblastic
leukemia
Splenomegaly is less common
than hepatomegaly
It is more common in adult
Testicular involvement is
common
It may progress to mycosis
fungoides
Q.) Confirmation of
myelofibrosis is usually
done by
Immunophenotyping
Bone marrow biopsy
Splenic aspiration
Bone marrow aspiration
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Q.) The following is NOT
a feature of blast cells
observed in leukemias
Thin rim to moderate amount
of cytoplasm
Nucleus with open chromatin
and 1 to 5 nucleoli
High N:C ratio
Large pleomorphic nuclei
Q.) In ALL, the
prognosis is unfavorable
When the total WBC count is
low
When the age of the patient is
between 2 to 10 years
In a female child
When Philadelphia
chromosome is present
Q.) The syndrome which
has an increased
predisposition for
leukemia is
Down syndrome
Klinefelter syndrome
Peutz Jeghers syndrome
Turner syndrome
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Q.) The monoclonal
antibodies which show
positivity in AML is
CD2 and CD3
CD13 and CD33
CD5 and CD7
CD10, CD19 and CD22
Q.) The cells associated
with formation of
chloroma are
Plasmablasts
Lymphoblasts
Myeloblasts
Immunoblasts
Q.) Myelodysplastic
syndrome has following
characteristics EXCEPT
There is a risk of development
of AML
It is a congenital stem cell
disorder
It is characterized by dysplasia
in non-lymphoid lineage
It shows megaloblastoid and
ineffective hematopoiesis
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Q.) The Cytochemical
stain which
distinguishes
Myeloblast from
Lymphoblast is
TRAP
Myeloperoxidase
Myeloesterase
Leukocyte Alkaline
Phosphatase
Q.) The cytochemical
stain which shows block
positivity in
lymphoblast is
Sudan black
PAS
Nonspecific esterase
Myeloperoxidase
Q.) The following is NOT
a common presenting
feature observed in AML
Hepatosplenomegaly frequent
Leukostasis common
Predominantly seen in adults
Leukemic meningitis common
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Q.) Following
biochemical feature is
NOT seen in tumor lysis
syndrome
Hyperuricosuria
Hyperkalemia
Hyperuricemia
Hypercalcemia
Q.) According to WHO,
the minimum
percentage of myeloid
blasts in bone marrow
necessary for the
diagnosis of AML is
20%
40%
10%
30%
Q.) The following
disorder shows pawn
ball megakaryocytes
Pernicious anemia
Hodgkin lymphoma
Immune thrombocytopenic
purpura
Myelodysplastic syndrome
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Q.) Auer rods are found
in the cytoplasm of
Lymphoblast
Monoblasts
Myeloblast
Megaloblast
Q.) Both pre-B and pre-
T lymphoblasts are
positive for
Alkaline phosphatase
Terminal deoxynucleotidyl-
transferase
CD19 and CD10
CD5 and CD8
Q.) The monoclonal
antibodies which show
positivity in B-lineage
ALL is
CD13 and CD33
CD2 and CD3
CD10, CD19 and CD22
CD5 and CD7
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Q.) Auer rods represent
Ribosomes
Azurophilic granules
Mitochondria
Secondary granules
Q.) The morphological
type of leukemia which
may show Auer rods is
Chronic myeloid leukemia
Acute Myeloid Leukemia
Acute lymphoblastic leukemia
Chronic lymphoid leukemia
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DRISHTI SHARMA
Hey, This is Drishti Sharma,
graduated with BSc. from
IGNOU and have completed
a Diploma in Medical
Laboratory Technology. I
love to write and share my words with the world.
I also engage myself in teaching which enhances
my creativity and makes me more expressible.
ACUTE LEUKEMIA ACUTE LEUKEMIA QUIZ
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PARAMEDICAL QUIZ QUIZ ON ACUTE LEUKEMIA
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