DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Granisetra Antiemetics Binds to serotonin To prevent Headache, Hypersensitivity 1.monitor hepatic
n : serotonin receptors in nausea & anxiety, to drug enzyme leves &
receptor chemoreceptor vomiting drowsiness, CBC
(Kytril) antagonist trigger zone and caused by dizziness, CAUTION: 2.monitor temp &
vagal nerve chemotherap diarrhea/ Pregnant or BP
terminal, blocking y constipation, breastfeeding 3.advice Px to
serotonin release abdominal pain px. minimize GI upset
& controlling Acute by eating
nausea& vomiting postoperative frequent small
n/v servings of
healthy foods.
ADVERSE EFFECTS
Anemia,
alopecia,
altered taste,
dec. appetite
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Ondasetro Antiemetics Block serotonin at To prevent Headacvhe, Hypersensitivity 1.Assess VS
n HCL 5-HT3 receptor nausea and dizziness, to drug 2.evaluate fluid
sites in vagal vomiting fatigue, intake and output
(zofran) nerve terminals caused by weakness Use cautiously 3.tell Px to take
by disrupting CNS moderately in: 30-60mins before
chemoreceptors emotogenicc Hepatic diseas a meal preferably
trigger zone hemotherapy Pregnant or In morning
ADVERSE EFFECTS
breasfeeding px 4.caution x to
Bronchospasm
avoid driving &
Urinary
other hazardous
retention
activities.
anaphylaxis
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Palonoset Antiemetics Selectively binds To prevent Pain, Hypersensitivity 1.Monitor liver
ron HCL to & antaginizes n/v caused by conjunctivitis, to drug and its function test &
5-HT3 receptors cancer sinusitis, components CBC
(aloxi) on vagal chemotherap diarrhea 2.assess Px
nerveterminals & y weight &
in chemoreceptor hydration status
ADVERSE EFFECTS
trigger zone. This 3.inform px that
Asthma, apnea
action blocks drug may cause
Fungal
serotonin release, GI symptoms &
dermatitis
reducing the failure to thrive.
cough
vomiting reflex Provide dietary
consultations
needed.
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
dronabino Antiemetics Unknown. May Prevention of Anxiety, Hypersensitivity 1.Monitor VS for
l : exert antiemetic n/v caused by irritability, to cannabinoids hypotension &
Cannabinoi effect by chemotherap headache, & breasfeeding tachycardia
(Marinol) ds inhibiting y 2.monitor
vomiting control Precaution: nutritional status
mechanism in ADVERSE EFFECTS Pregnant and hydration
medulla Suicidal woman & 3.caution Px to
oblongata ideation HPN avoid driving &
Diaphoresis other hazardous
Syncope activities until he
Visual knows how drug
disturbances affects
concentration &
alertness
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Antiemetics Augments To prevent Headache, Hypersensitivity 1.assess
Aprepitan : antiemetics acute & fatigue, to drug nutritional &
t miscellaneo activity of delayed n/v anorexia, hydration status
us ondansetronand caused by abdominal pain Concurrent
(Emend) dexamethasone. highly primozide or 2.tell Px that
Also inhibits emotogenic crisapide drugs may cause
ADVERSE EFFECTS
cisplatin-induced cancer therapy CNS effects.
Neutropenia
emesis chemotherap Explain that he’ll
Hiccups
y; breastfeeding be monitored to
Tinnitus
ensure his safety
gastritis
Postoperative
n/v 33.advise px to
minimize GI upset
by eating small,
frequent serving
food & drinking of
plenty of fluids.
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Haloperid Antipsychot Unknown. Symptomatic Restlessness, Hypersensitivity 1.monitor CNS
ol ic: Thought to block treatment of drowsiness to drug, status closely,
butyrophen postsynaptic psychotic Sedation, tartazine, especially for
(haldol) ones dopamine disorders or Lethargy sesame oil or seizures &
receptors in brain tourette insomia benzyl alcohol Neuroleptic
& increase syndrome malignat
dopamine Severe CNS syndrome
turnover rate, depression 2.assess
inhibiting sings & ADVERSE EFFECTS respiratoy status
symptoms of Seizures 3.tell Px to di;lute
psychosis. Neuroleptic oral concentrate
malignat w/ water, cola or
syndrome juice immediately
Drug-indced before taking.
hepatitis 3.advise px to
bronchospasm minimize GI upset
by eating
frequent, small
servings of food &
drinking adequate
fluid.
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Diazepam Anticonvuls Produces Anxiety Hypersensitivity 1.enforce bedrest
ant, anxiolytic effect & disorders Dizziness, to drug, other for atleast 3hrs
(valium) sedative- CNS depression by lethargy, light- benzodiapines, after IV injection
hypnotic: stimulating Status headedness, alcohol or 2.avoid sudden
benzodiaze gamma epilepticus & restlessness, tartrazine drug withdrawal.
pines aminobutyric acid severe headache, Taper dosage
receptors. Relaxes recurrent tachycardia Coma or CNS gradually to
skeletal muscles convulsive depression termination of
of spine by seizures therapy.
inhibiting ADVERSE EFFECTS Narrow angle 3.inform Px that
polysynaptic Cardiovascular glaucoma he may take drug
afferent collapse. w/ or w/o food;
pathways. Control Thrombocytope recommend
seizures by nia. taking it w/ food
enhancing Hepatic if causes stomach
presynaptic dysfunction. upset.
inhibition. Respiratory 4.instruct px to
depression. move slowly
when sitting up or
standing to avoid
dizziness.
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Glucocortic Reduces anti Allergic & Headache, Hypersensitivity 1.monitor Hgb &
Dexameth oid inflammation by inflammatory malaise, to drug, benzyl Potassium level.
asone suppressing condition vertigo,hypoten alcohol, 2.tell Px to take
polymorphonucle sion, muscle creatinine or oral drug with or
(decadron ar leukocute cerebral pain, methylparaben after meals
) migration, edema diaphoresis, n/v 3.Inform Px that
reversing Facial edema Systemic fungal drugs make him
increased capillary infection susceptible to
permeability & ADVERSE EFFECTS infection. Advise
stabilizing Peptic ulcer. him to avoid
leukocyte Increased crowds &
lysosomal intracranial exposure to
membranes. pressure. illness.
Thromboemboli
sm.
Hypokalemic
alkalosis.
seizures
DRUG CLASSIFICA MECHANISM OF INDICATIONS SIDE EFFECTS CONTRAINDICA NURSING
NAME TION ACTION TION CONSIDERATIONS
Glucocortic Reduces Diseases 7 Headache, Hypersensitivity 1.Monitor fluid &
Methylpre oids inflammatuion & disordered of restlessness, to drug, or its electrolytes
dnisolone reduces edema by endocrine hypotension, components balance, weight
stabilizing system, nasal irritation, & BP.
(medrol) membranes 7 sollagen, skin, amenorrhea, Systemic fungal 2.tell Px to take
reducing eye, GI tract, cough, infection with food to
permeability of respiratory & hypokalemia minimize GI
leukocytic cells. hematologic upset.
Suppresses system/ ADVERSE EFFECTS 3.Advise diabetic
immune system ESOPHAGEAL Px to monitor
ULCER, PEPTIC
by interfering w/ ULCER, blood glucose
antigen-antibody PANCREATITIS, level carefully.
interact=ions of BRONCHOSPASM 4.Advise Px to
microphages & T ADRENAL report unusual
SUPPRESION,
cells. weight gain,
OSTEOPOROSIS
swelling, muscle
weakness, black
tarry stools, sore
throat or
infection.
