Prevalence of Temporomandibular Disorders and Assessment of Factors Associated With It - A Retrospective Study
Prevalence of Temporomandibular Disorders and Assessment of Factors Associated With It - A Retrospective Study
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1
Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University,
Chennai 600077, Tamil Nadu, India.
2
Senior Lecturer, Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha
University, Chennai 600077, Tamil Nadu, India.
Abstract
E The temporomandibular joint has many anatomic and functional features that make it one of the most complex joints of
the body. Temporomandibular disorders are a complex group of conditions involving the temporomandibular joint, disc or
masticatory muscles. This condition causes a physical and psychological debility in the population, as the pain is widespread
and causes disability. Patients can also have clicking or grating sounds, limited or asymmetrical jaw movement. Even though
it is not a life threatening disease, the quality of life is reduced. The aim of this study was to evaluate the prevalence of tem-
poromandibular disorders and assessment of factors associated with it. A retrospective study was conducted in the Saveetha
Dental College. Ethical clearance was obtained from SRB committee, Saveetha Dental College. Data was collected from a total
of 86000 patients who visited Saveetha dental college between Jun,2019 to March,2020. Out of this, the data of 69 patients
who had pain in the TMJ in this time frame were retrieved. The data obtained was tabulated in SPSS for windows, version 20.
Frequencies were analysed. Chi square test was done to analyse association. There is no significant association between type
of TMD with age (P=0.342), gender (P=0.950) and dental status (P=0.404) in the present study. Within the limitations of this
study, TMD was more predominant in males, disc displacement was more predominant and the most affected age group was
between 30-39 years of age.
Keywords: Temporomandibular Disorders; Tmd; Condylar Disc Disorder; Mpds; Degenerative Disorders.
Introduction cal debility in the population, as the pain is widespread and causes
disability. Patients can also have clicking or grating sounds, limited
The temporomandibular joint has many anatomic and functional or asymmetrical jaw movement. Even though it is not a life threat-
features that make it one of the most complex joints of the body ening disease, the quality of life is reduced [5, 62, 7].
[11]. The part of the mandible in the TMJ is the condyle. Con-
dylar remodeling is continuous even after cessation of growth. It TMD can be caused by trauma, grinding and clenching of teeth,
is associated with ageing. Condylar remodeling is a physiological, disc slip, stress, osteoarthritis and rheumatoid arthritis [16]. Also,
adaptive process. It is the adaptation of the structure of the con- a hereditary problem named joint hypermobility where there is
dyle to meet the functional demands [3]. While evaluating pano- increased range of motion in all joints. This is called TMJ hy-
ramic radiographs, this adaptive mechanism must be kept in mind. permobility. Winocur et al, after conducting a study about the
Temporomandibular disorders are a complex group of condi- prevalence of general joint laxity and TMJ hypermobility among
tions involving the temporomandibular joint, disc or masticatory adolescent girls, stated that there was a 43% prevalence of gen-
muscles. It is characterized by chronic facial pain. Sometimes, it eralized joint laxity and out of which 27.3% was recognised as
is also associated with other comorbidities, like chronic joint and TMJH [68]. Adair et al, conducted a survey where they discovered
muscle pain [1]. This condition causes a physical and psychologi- that patients with generalized joint hypermobility were more likely
*Corresponding Author:
Revathi Duraisamy,
Senior Lecturer, Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077,
Tamil Nadu, India.
Tel: +91-7598267022
E-mail: [email protected]
Citation: Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral
Sci. 2021;8(8):3871-3876.
Copyright: Revathi Duraisamy©2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,
distribution and reproduction in any medium, provided the original author and source are credited.
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
3876.
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to show signs and symptoms of TMD than ones with normal Priyadharsini and Raghunandhakumar, 2020 [45]), (Palati et al.,
joint mobility [68]. Types of TMD include disc condyle disorder, 2020 [43]), (Samuel, Acharya and Rao, 2020 [50]) Now the grow-
MPDS and degenerative disorder [9]. ing trend in this area motivated us to pursue this project.
Certain genetic factors, like polymorphisms in COMT - catechol The purpose of this study was to evaluate the prevalence of tem-
- O - methyltransferase - and ADRB2 – beta - 2 adrenoceptor poromandibular disorders.
genes, are likely to be responsible for hypersensitivity to experi-
mental pain in at least 50% of the cases studied. These same fac- Materials And Methods
tors may make individuals more susceptible to developing chronic
pain throughout life [25]. Joint pains can also be associated with A retrospective study was conducted in the Saveetha Dental Col-
systemic factors like, hormonal changes, autoimmune diseases, lege, Chennai, India. Ethical clearance was obtained from SRB
bacterial and viral infiltration, tissue metabolism, etc [59, 63, 32, committee, Saveetha Dental College, Chennai, India. The clinical
8]. portion of this retrospective study was conducted over a 9 month
period,i.e, between June, 2019 to March,2020 and included pa-
Several studies state that females have more predilections for tients who came with pain in the TMJ.
TMD due to stress and hormonal changes [36, 48, 57]. Dental sta-
tus like occlusal interference, loss of teeth, loss of vertical dimen- Inclusion criteria: Patients who came with pre-existing pain in
sion, excess vertical dimension in removable or fixed prosthesis, TMJ, both males and females.
orthodontic treatment, parafunctional habits like clenching and
bruxism, and talking with phone over shoulder [24, 52, 25, 27]. Exclusion criteria: Patients in whom only clicking was present
Dental treatments like implant placements, extraction of teeth, without any pain.
etc exacerbate the pain [2, 25, 17]. Different studies state different
relationships between age and TMD. According to Österberg T et Data was collected from a total of 86000 patients who visited
al, neither the variation in TMD symptoms between various age Saveetha dental college between Jun, 2019 to March,2020. Out of
groups and with time is fully understood, nor is the etiology of this, the data of 69 patients who had pain in this time frame were
TMD clarified [41]. However Ferreira et al stated a higher occur- retrieved. The data obtained was tabulated in SPSS for windows,
rence in young adults [21]. version 20. Frequencies were analysed. Chi square test was done
to analyse correlation.
Previously our team has a rich experience in working on various
research projects across multiple disciplines. (Jain, 2017 [31]), Results
(Varghese, Ramesh and Veeraiyan, 2019 [61]), (Ashok and Ga-
napathy, 2019 [6]), (Padavala and Sukumaran, 2018 [42]), (Ke et In the present study 55.1% were males and 44.9% were females
al., 2019 [34]), (Krishnan et al., 2018 [6]), (Ezhilarasan, Sokal and [Figure 1].13% of the patients were <20 years, 21.7% of the pa-
Najimi, 2018 [20]), (Pandian, Krishnan and Kumar, 2018 [44]), tients were between 20-29 years of age, 40.6% of the patients
(Ramamurthy and Mg, 2018 [50]), (Gupta, Ariga and Deogade, were between 30-39 years of age, 14.5% of the patients were be-
2018 [27]), (Vikram et al., 2017 [66]), (Paramasivam, Vijayashree tween 40-49 years of age, 8.7% of the patients were 50-59 years
Figure 1 - Bar graph represents the association between gender and type of TMD. X-axis represents the gender and Y-axis represents the
percentage of patients with TMD. Chi-square test was done.(Pearson Chi-square P value:0.950(>0.05), hence not statistically significant).
There is no statistically significant association between gender and type of TMD.
Figure 2 - Bar graph represents the association between age and type of TMD(. X-axis represents the age and Y-axis represents the percent-
age of patients with TMD. Chi-square test was done. (Pearson Chi-square P value: 0.342(>0.05), hence not statistically significant). There
is no significant association between age and type of TMD.
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
3876.
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Figure 3 - Bar graph represents the association between dental status and type of TMD. X-axis represents the dental status and Y-axis
represents the percentage of patients with TMD. Chi-square test was done and association was not found to be statistically significant.
(Pearson Chi-square P value:0.404(>0.05), hence not statistically significant). There is no significant association between dental status
and type of TMD.
Table 1 - Represents the frequencies of age, gender, type of TMD, dental status of participants.
of age, 1.4% of the patients were between 60-69 years of age restorations, 2.9% had crowns, 15.9% were partially edentulous,
[Figure 2]. 59.4% had Disc condylar disorder, 33.3% had MPDS, 2.9% were completely edentulous, and 36.2% had non carious
and 7.2% had degenerative disorder. 27.5% had caries, 14.5% had lesions [Figure 3].
restorations, 2.9% had crowns, 15.9% were partially edentulous,
2.9% were completely edentulous, 36.2% had non carious lesions In the present study, males with TMD were more predominant
[Figure 3][Table 1]. than females. But there was no significant correlation between
type of TMD with gender (P=.950). Haissam Dahan et al state
There was no significant correlation between Type of TMD with that gender is a major confounder in TMD [15]. Korszun et al,
gender (P=.950), age (P=.342), Dental status (P=.404) and sys- Contreras et al, Gonçalves DA, Österberg et al, Plesh et al, also
temic diseases (P=.205). Significance level was set at P<0.05. stated that TMD is more predominant in women due to an in-
creased predominance of stress related disorders (Website, no
Discussion date; [35, 41, 48, 13] Bonato et al stated that 82.5% of their sam-
ple population with TMD was women [10]. A study done by Fill-
In the present study 55.1% were males and 44.9% were females ingim et al on chronic TMD patients stated that women reported
[Figure 1].13% of the patients were <20 years, 21.7% of the pa- with higher levels of psychological distress across several SCL-
tients were between 20-29 years of age, 40.6% of the patients 90R scales, along with greater neuroticism, perceived stress, nega-
were between 30-39 years of age, 14.5% of the patients were be- tive affect, and somatic awareness. Women also reported greater
tween 40-49 years of age, 8.7% of the patients were 50-59 years use of catastrophizing, distraction, and praying & hoping, while
of age, 1.4% of the patients were between 60-69 years of age men reported higher scores on coping self-statements, and ignor-
[Figure 2]. 59.4% had Disc condylar disorder, 33.3% had MPDS, ing and reinterpreting pain sensations [2]. Another study done by
and 7.2% had degenerative disorder. 27.5% had caries, 14.5% had Ferreira CL et al stated that the number of women who presented
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
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a higher prevalence of painful symptoms was greater, followed by of age. There is no significant association between type of TMD
otologic symptoms and complaints of dysphonia [21]. However, with age, gender and dental status in the present study.
Hiltunen et al stated that no differences based on gender were
found [29]. References
Disc condylar disorder was more predominant in this study. How- [1]. Afroz S, Naritani M, Hosoki H, Takechi K, Okayama Y, Matsuka Y. Preva-
lence of Posterior Disc Displacement of the Temporomandibular Joint in
ever, in a study by Yap et al, Mpds was more common. Bertoli et Patients with Temporomandibular Disorders: Systematic Review and Meta-
al and Franco-Micheloni et al also stated that MPDS is most com- Analyses. J Oral Facial Pain Headache. 2018 Summer;32(3):277–286. Pub-
mon followed by disc displacement and degenerative disorders med PMID: 29697716.
[23, 9]. [2]. Ajay R, Suma K, Ali SA, Kumar Sivakumar JS, Rakshagan V, Devaki V, Di-
vya K. Effect of Surface Modifications on the Retention of Cement-retained
Implant Crowns under Fatigue Loads: An In vitro Study. J Pharm Bioallied
In the present study, patients were predominantly between 30- Sci. 2017 Nov;9(Suppl 1):S154-S160. Pubmed PMID: 29284956.
39 years of age. This concurs with Bonato et al, who stated that [3]. Araujo AM, Buschang PH, Melo AC. Adaptive condylar growth and man-
TMD is more prevalent in women between 20 and 40 years [10]. dibular remodelling changes with bionator therapy--an implant study. Eur J
Orthod. 2004 Oct;26(5):515-22. Pubmed PMID: 15536840.
However, Plesh et al stated that for females, headache or migraine [4]. Jain AR, Nallaswamy D, Ariga P, Ganapathy DM. Determination of correla-
pain with TMJ pain peaked around age 40 and decreased after- tion of width of maxillary anterior teeth using extraoral and intraoral factors
wards. Joint pains increased with age regardless of gender [48]. in Indian population: A systematic review. World J Dent. 2018 Jan;9(1):68-
Ferreira et al stated a higher occurrence in young adults [19 to 40 75.
[5]. Ashok V, Nallaswamy D, Benazir Begum S, Nesappan T. Lip Bumper Pros-
years old] [21]. Contreras et al stated that TMD onset tends to thesis for an Acromegaly Patient: A Clinical Report. J Indian Prosthodont
occur after puberty, and the increase in the severity of signs and Soc. 2014 Dec;14(Suppl 1):279-82. Pubmed PMID: 26199531.
symptoms generally reaches its peak during the reproductive age [6]. Ashok V, Ganapathy D. A geometrical method to classify face forms. J Oral
[48, 13]. However, Hiltunen et al stated that no differences based Biol Craniofac Res. 2019 Jul-Sep;9(3):232-235. Pubmed PMID: 31198677.
[7]. Ashok V, Suvitha S. Awareness of all ceramic restoration in rural population.
on age were found [29]. But there was no significant association Res J Pharm Technol. 2016;9(10):1691-3.
between types of TMD and age (P=.342) in the present study. [8]. Basha FY, Ganapathy D, Venugopalan S. Oral hygiene status among preg-
nant women. Res J Pharm Technol. 2018;11(7):3099-102.
27.5% had caries, 14.5% had restorations, 2.9% had crowns, [9]. Bertoli FMP, Bruzamolin CD, Pizzatto E, Losso EM, Brancher JA, de Souza
JF. Prevalence of diagnosed temporomandibular disorders: A cross-sectional
15.9% were partially edentulous, 2.9% were completely edentu- study in Brazilian adolescents. PLoS One. 2018 Feb 8;13(2):e0192254. Pub-
lous, and 36.2% had non carious lesions in the present study. But med PMID: 29420573.
there was no significant correlation between type of TMD with [10]. Bonato LL, Quinelato V, De Felipe Cordeiro PC, De Sousa EB, Tesch R,
dental status (P=.950). Mathew et al Pereira et al., Sato et al., Hil- Casado PL. Association between temporomandibular disorders and pain in
other regions of the body. J Oral Rehabil. 2017 Jan;44(1):9-15. Pubmed
tunen et al., Crow et al., and Takayama et al., stated that there is no PMID: 27862166.
significant association between degenerative changes in the con- [11]. Calogero F. A complex deformation of the classical gravitational many-body
dyle with dentition status [47, 56, 29, 14, 60]. However, Muir et al, problem that features many completely periodic motions. Journal of Physics
Giesen et al., and Harriman et al were not in agreement [28, 40, A: Mathematical and General. 2002 Apr 12;35(16):3619.
[12]. Chandrasekar R, Chandrasekhar S, Sundari KKS, Ravi P. Development and
26]. Österberg et al stated that the TMD index was significantly validation of a formula for objective assessment of cervical vertebral bone
associated with bruxism [41]. Huang et al reported a correlation age. Prog Orthod. 2020 Oct 12;21(1):38. Pubmed PMID: 33043408.
between third molar extraction and TMD [30]. Moon et al stated [13]. Contreras EFR, Fernandes G, Ongaro PCJ, Campi LB, Gonçalves DAG.
that loss of occlusion and centric relation causes loss of equilib- Systemic diseases and other painful conditions in patients with temporo-
mandibular disorders and migraine. Braz Oral Res. 2018 Jul 23;32:e77. Pub-
rium leading to TMJ and postural problems[39]. med PMID: 30043839.
[14]. Crow HC, Parks E, Campbell JH, Stucki DS, Daggy J. The utility of pano-
The limitations of this study were firstly,the small sample size. ramic radiography in temporomandibular joint assessment. Dentomaxillofac
Secondly, the entire sample was taken from a similar geographic Radiol. 2005 Mar;34(2):91-5. Pubmed PMID: 15829691.
[15]. Dahan H, Shir Y, Velly A, Allison P. Specific and number of comorbidities
location. Thirdly, systemic diseases were not assessed. Further are associated with increased levels of temporomandibular pain intensity and
studies need to be done with a larger sample size to assess the duration. J Headache Pain. 2015;16:528. Pubmed PMID: 26002637.
prevalence of TMD with systemic diseases. Our institution is pas- [16]. Dougall AL, Sanders C. Chronic pain in a specific population: temporoman-
sionate about high quality evidence based research and has ex- dibular joint and muscle disorders. Chronic Pain. 2013;75–91.
[17]. Duraisamy R, Krishnan CS, Ramasubramanian H, Sampathkumar J, Mari-
celled in various fields ( (Pc, Marimuthu and Devadoss, 2018 [46]; appan S, Navarasampatti Sivaprakasam A. Compatibility of Nonoriginal
Ramesh et al., 2018 [51]; Vijayashree Priyadharsini, Smiline Girija Abutments With Implants: Evaluation of Microgap at the Implant-Abut-
and Paramasivam, 2018 [65]; Ezhilarasan, Apoorva and Ashok ment Interface, With Original and Nonoriginal Abutments. Implant Dent.
Vardhan, 2019 [19]; Ramadurai et al., 2019 [49]; Sridharan et al., 2019 Jun;28(3):289-295. Pubmed PMID: 31124826.
[18]. Ezhilarasan D. Oxidative stress is bane in chronic liver diseases: Clinical and
2019 [58]; Vijayashree Priyadharsini, 2019 [64]; Chandrasekar et experimental perspective. Arab J Gastroenterol. 2018 Jun;19(2):56-64. Pub-
al., 2020 [12]; Mathew et al., 2020 [38]; R et al., 2020; Samuel, 2021 med PMID: 29853428.
[53]). We hope this study adds to this rich legacy. [19]. Ezhilarasan D, Apoorva VS, Ashok Vardhan N. Syzygium cumini extract in-
duced reactive oxygen species-mediated apoptosis in human oral squamous
carcinoma cells. J Oral Pathol Med. 2019 Feb;48(2):115-121. Pubmed
Conclusion PMID: 30451321.
[20]. Ezhilarasan D, Sokal E, Najimi M. Hepatic fibrosis: It is time to go with
The present study was conducted to understand the prevalence hepatic stellate cell-specific therapeutic targets. Hepatobiliary Pancreat Dis
Int. 2018 Jun;17(3):192-197. Pubmed PMID: 29709350.
of temporomandibular disorders and assessment of factors as- [21]. Ferreira CL, Silva MA, Felício CM. Signs and symptoms of temporoman-
sociated with it. Within the limitations of this study, TMD was dibular disorders in women and men. Codas. 2016 Jan-Feb;28(1):17-21.
more predominant in males, disc displacement was more com- Pubmed PMID: 27074184.
mon and the most affected age group was between 30-39 years [22]. Fillingim RB, Ohrbach R, Greenspan JD, Knott C, Dubner R, Bair E, Bara-
ian C, Slade GD, Maixner W. Potential psychosocial risk factors for chronic
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
3876.
3874
OPEN ACCESS https://scidoc.org/IJDOS.php
TMD: descriptive data and empirically identified domains from the OP- [43]. Palati S, Ramani P, Shrelin HJ, Sukumaran G, Ramasubramanian A, Don
PERA case-control study. J Pain. 2011 Nov;12(11 Suppl):T46-60. Pubmed KR, Jayaraj G, Santhanam A. Knowledge, Attitude and practice survey on
PMID: 22074752. the perspective of oral lesions and dental health in geriatric patients residing
[23]. Franco-Micheloni AL, Fernandes G, de Godoi Gonçalves DA, Camparis in old age homes. Indian J Dent Res. 2020 Jan-Feb;31(1):22-25. Pubmed
CM. Temporomandibular Disorders in a Young Adolescent Brazilian Popu- PMID: 32246676.
lation: Epidemiologic Characterization and Associated Factors. J Oral Facial [44]. Pandian KS, Krishnan S, Kumar SA. Angular photogrammetric analysis of
Pain Headache. 2015 Summer;29(3):242-9. Pubmed PMID: 26244432. the soft-tissue facial profile of Indian adults. Indian J Dent Res. 2018 Mar-
[24]. Ganapathy D, Sathyamoorthy A, Ranganathan H, Murthykumar K. Effect Apr;29(2):137-143. Pubmed PMID: 29652003.
of Resin Bonded Luting Agents Influencing Marginal Discrepancy in All Ce- [45]. Paramasivam A, Vijayashree Priyadharsini J, Raghunandhakumar S. N6-
ramic Complete Veneer Crowns. J Clin Diagn Res. 2016 Dec;10(12):ZC67- adenosine methylation (m6A): a promising new molecular target in hyper-
ZC70. Pubmed PMID: 28209008. tension and cardiovascular diseases. Hypertens Res. 2020 Feb;43(2):153-
[25]. Ganapathy DM, Kannan A, Venugopalan S. Effect of coated surfaces influ- 154. Pubmed PMID: 31578458.
encing screw loosening in implants: A systematic review and meta-analysis. [46]. J PC, Marimuthu T, C K, Devadoss P, Kumar SM. Prevalence and measure-
World Journal of Dentistry. 2017 Nov;8(6):496-502. ment of anterior loop of the mandibular canal using CBCT: A cross sectional
[26]. Giesen EB, Ding M, Dalstra M, van Eijden TM. Changed morphology study. Clin Implant Dent Relat Res. 2018 Aug;20(4):531-534. Pubmed
and mechanical properties of cancellous bone in the mandibular condyles PMID: 29624863.
of edentate people. J Dent Res. 2004 Mar;83(3):255-9. Pubmed PMID: [47]. Pereira FJ Jr, Lundh H, Westesson PL. Morphologic changes in the temporo-
14981130. mandibular joint in different age groups. An autopsy investigation. Oral Surg
[27]. Gupta P, Ariga P, Deogade SC. Effect of Monopoly-coating Agent on the Oral Med Oral Pathol. 1994 Sep;78(3):279-87. Pubmed PMID: 7970585.
Surface Roughness of a Tissue Conditioner Subjected to Cleansing and [48]. Plesh O, Adams SH, Gansky SA. Self-reported comorbid pains in se-
Disinfection: A Contact Profilometric In vitro Study. Contemp Clin Dent. vere headaches or migraines in a US national sample. Headache. 2012
2018 Jun;9(Suppl 1):S122-S126. Pubmed PMID: 29962776. Jun;52(6):946-56. Pubmed PMID: 22553936.
[28]. Harriman LP, Snowdon DA, Messer LB, Rysavy DM, Ostwald SK, Lai [49]. Ramadurai N, Gurunathan D, Samuel AV, Subramanian E, Rodrigues SJL.
CH, Soberay AH. Temporomandibular joint dysfunction and selected Effectiveness of 2% Articaine as an anesthetic agent in children: randomized
health parameters in the elderly. Oral Surg Oral Med Oral Pathol. 1990 controlled trial. Clin Oral Investig. 2019 Sep;23(9):3543-3550. Pubmed
Oct;70(4):406-13. doi: 10.1016/0030-4220(90)90199-3. PMID: 2216377. PMID: 30552590.
[29]. Hiltunen K, Vehkalahti MM, Peltola JS, Ainamo A. A 5-year follow-up [50]. Ramamurthy JA, Mg V. Comparison of effect of Hiora mouthwash versus
of occlusal status and radiographic findings in mandibular condyles of the Chlorhexidine mouthwash in gingivitis patients: A clinical trial. Asian J
elderly. Int J Prosthodont. 2002 Nov-Dec;15(6):539-43. Pubmed PMID: Pharm Clin Res. 2018 Jul 7;11(7):84-8.
12475158. [51]. Ramesh A, Varghese S, Jayakumar ND, Malaiappan S. Comparative estima-
[30]. Huang GJ, LeResche L, Critchlow CW, Martin MD, Drangsholt MT. Risk tion of sulfiredoxin levels between chronic periodontitis and healthy patients
factors for diagnostic subgroups of painful temporomandibular disorders - A case-control study. J Periodontol. 2018 Oct;89(10):1241-1248. Pubmed
(TMD). J Dent Res. 2002 Apr;81(4):284-8. Pubmed PMID: 12097315. PMID: 30044495.
[31]. Jain AR. Prevalence of partial edentulousness and treatment needs in rural [52]. Ranganathan H, Ganapathy DM, Jain AR. Cervical and Incisal Marginal
population of South India. World Journal of Dentistry. 2017 Jun;8(3):213- Discrepancy in Ceramic Laminate Veneering Materials: A SEM Analy-
7. sis. Contemp Clin Dent. 2017 Apr-Jun;8(2):272-278. Pubmed PMID:
[32]. Jyothi S, Robin PK, Ganapathy D. Periodontal health status of three dif- 28839415.
ferent groups wearing temporary partial denture. Res J Pharm Technol. [53]. R H, Ramani P, Ramanathan A, R JM, S G, Ramasubramanian A, K M.
2017;10(12):4339-42. CYP2 C9 polymorphism among patients with oral squamous cell carcinoma
[33]. Veitz-Keenan A, Keenan JR. To cord or not to cord? That is still a question. and its role in altering the metabolism of benzo[a]pyrene. Oral Surg Oral
Evid Based Dent. 2017 Mar;18(1):21-22. Pubmed PMID: 28338036. Med Oral Pathol Oral Radiol. 2020 Sep;130(3):306-312. Pubmed PMID:
[34]. Ke Y, Al Aboody MS, Alturaiki W, Alsagaby SA, Alfaiz FA, Veeraraghavan 32773350.
VP, Mickymaray S. Photosynthesized gold nanoparticles from Catharanthus [54]. Samuel SR. Can 5-year-olds sensibly self-report the impact of develop-
roseus induces caspase-mediated apoptosis in cervical cancer cells (HeLa). mental enamel defects on their quality of life? Int J Paediatr Dent. 2021
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):1938-1946. Pubmed Mar;31(2):285-286. Pubmed PMID: 32416620.
PMID: 31099261. [55]. Samuel SR, Acharya S, Rao JC. School Interventions-based Prevention of
[35]. Korszun A, Papadopoulos E, Demitrack M, Engleberg C, Crofford L. The Early-Childhood Caries among 3-5-year-old children from very low socio-
relationship between temporomandibular disorders and stress-associated economic status: Two-year randomized trial. J Public Health Dent. 2020
syndromes. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Jan;80(1):51-60. Pubmed PMID: 31710096.
Oct;86(4):416-20. Pubmed PMID: 9798224. [56]. Sato H, Osterberg T, Ahlqwist M, Carlsson GE, Gröndahl HG, Rubinstein
[36]. Korszun A, Dinos S, Ahmed K, Bhui KS. Response to Prabhakar et al. Let- B. Association between radiographic findings in the mandibular condyle and
ter. Acad Psychiatry. 2012 Nov;36(6):500. doi: 10.1176/appi.ap.12080154. temporomandibular dysfunction in an elderly population. Acta Odontol
Erratum in: Acad Psychiatry. 2013 May;37(3):186. Pubmed PMID: Scand. 1996 Dec;54(6):384-90. Pubmed PMID: 8997438.
27517703. [57]. Selvan SR, Ganapathy D. Efficacy of fifth generation cephalosporins against
[37]. Krishnan RP, Ramani P, Sherlin HJ, Sukumaran G, Ramasubramanian A, methicillin-resistant Staphylococcus aureus-A review. Res J Pharm Technol.
Jayaraj G, Don KR, Santhanam A. Surgical Specimen Handover from Op- 2016;9(10):1815-8.
eration Theater to Laboratory: A Survey. Ann Maxillofac Surg. 2018 Jul- [58]. Sridharan G, Ramani P, Patankar S, Vijayaraghavan R. Evaluation of salivary
Dec;8(2):234-238. Pubmed PMID: 30693238. metabolomics in oral leukoplakia and oral squamous cell carcinoma. J Oral
[38]. Mathew MG, Samuel SR, Soni AJ, Roopa KB. Evaluation of adhesion of Pathol Med. 2019 Apr;48(4):299-306. Pubmed PMID: 30714209.
Streptococcus mutans, plaque accumulation on zirconia and stainless steel [59]. Subasree S, Murthykumar K. Effect of aloe vera in oral health-A review.
crowns, and surrounding gingival inflammation in primary molars: rand- Research Journal of Pharmacy and Technology. 2016;9(5):609-12.
omized controlled trial. Clin Oral Investig. 2020 Sep;24(9):3275-3280. doi: [60]. Takayama Y, Miura E, Yuasa M, Kobayashi K, Hosoi T. Comparison of oc-
10.1007/s00784-020-03204-9. Epub 2020 Jan 18. PMID: 31955271. clusal condition and prevalence of bone change in the condyle of patients
[39]. Moon HJ, Lee YK. The relationship between dental occlusion/temporoman- with and without temporomandibular disorders. Oral Surg Oral Med Oral
dibular joint status and general body health: part 1. Dental occlusion and Pathol Oral Radiol Endod. 2008 Jan;105(1):104-12. Pubmed PMID:
TMJ status exert an influence on general body health. J Altern Complement 17449297.
Med. 2011 Nov;17(11):995-1000. Pubmed PMID: 22070442. [61]. Varghese SS, Ramesh A, Veeraiyan DN. Blended Module-Based Teaching in
[40]. Muir CB, Goss AN. The radiologic morphology of asymptomatic temporo- Biostatistics and Research Methodology: A Retrospective Study with Post-
mandibular joints. Oral Surg Oral Med Oral Pathol. 1990 Sep;70(3):349- graduate Dental Students. J Dent Educ. 2019 Apr;83(4):445-450. Pubmed
54. Pubmed PMID: 2216365. PMID: 30745352.
[41]. Osterberg T, Carlsson GE. Relationship between symptoms of temporoman- [62]. Venugopalan S, Ariga P, Aggarwal P, Viswanath A. Magnetically retained
dibular disorders and dental status, general health and psychosomatic factors silicone facial prosthesis. Niger J Clin Pract. 2014 Mar-Apr;17(2):260-4.
in two cohorts of 70-year-old subjects. Gerodontology. 2007 Sep;24(3):129- Pubmed PMID: 24553044.
35. Pubmed PMID: 17696889. [63]. Vijayalakshmi B, Ganapathy D. Medical management of cellulitis. Res J
[42]. Padavala S, Sukumaran G. Molar Incisor Hypomineralization and Its Preva- Pharm Technol. 2016;9(11):2067-70.
lence. Contemp Clin Dent. 2018 Sep;9(Suppl 2):S246-S250. Pubmed [64]. Vijayashree Priyadharsini J. In silico validation of the non-antibiotic drugs
PMID: 30294152. acetaminophen and ibuprofen as antibacterial agents against red complex
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
3876.
3875
OPEN ACCESS https://scidoc.org/IJDOS.php
pathogens. J Periodontol. 2019 Dec;90(12):1441-1448. Pubmed PMID: [67]. Gonçalves DA, Camparis CM, Speciali JG, Franco AL, Castanharo SM,
31257588. Bigal ME. Temporomandibular disorders are differentially associated with
[65]. Vijayashree Priyadharsini J, Smiline Girija AS, Paramasivam A. In silico headache diagnoses: a controlled study. Clin J Pain. 2011 Sep;27(7):611-5.
analysis of virulence genes in an emerging dental pathogen A. baumannii Pubmed PMID: 21368664.
and related species. Arch Oral Biol. 2018 Oct;94:93-98. Pubmed PMID: [68]. Winocur E, Gavish A, Halachmi M, Bloom A, Gazit E. Generalized joint
30015217. laxity and its relation with oral habits and temporomandibular disorders in
[66]. Vikram NR, Prabhakar R, Kumar SA, Karthikeyan MK, Saravanan R. Ball adolescent girls. J Oral Rehabil. 2000 Jul;27(7):614-22. Pubmed PMID:
Headed Mini Implant. J Clin Diagn Res. 2017 Jan;11(1):ZL02-ZL03. Pub- 10931255.
med PMID: 28274084.
Sanjana Devi, Revathi Duraisamy. Prevalence of Temporomandibular Disorders and Assessment of Factors Associated with it - A Retrospective Study. Int J Dentistry Oral Sci. 2021;8(8):3871-
3876.
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