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NIPER Previous Questions Discussion

The document discusses various topics related to pharmacology, including methods of drug delivery such as iontophoresis and sonophoresis, and lists molecular modeling software. It also provides information on dielectric constants, isoelectric pH values of different substances, and mentions recent pharmaceutical approvals by Aurobindo Pharma. Additionally, it references the need to study FDA approved drugs from 2008 to 2011.

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Vikash Kushwaha
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122 views2 pages

NIPER Previous Questions Discussion

The document discusses various topics related to pharmacology, including methods of drug delivery such as iontophoresis and sonophoresis, and lists molecular modeling software. It also provides information on dielectric constants, isoelectric pH values of different substances, and mentions recent pharmaceutical approvals by Aurobindo Pharma. Additionally, it references the need to study FDA approved drugs from 2008 to 2011.

Uploaded by

Vikash Kushwaha
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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www.pharmacornergpat.blogspot.

com

NIPER previous questions discussion:

hydrogen bonding interactions between two polymers can be studied by


a.IR
b.mass
c.XRD
d.none

do al FDA approved drugs -2011-10-09. all ranges and basics from pavia. do LCMS, GCMS,
MSMS & biotech part & basics fm new edition of satynarayana

Iontophoresis:Low volt. current (<0.5ma/cm2) 2 drive charged drugs thru skin.


Electroporation:high volt. current in form of pulse.

Sonophoresis/phonophoresis:
Power ultrasound(Low freq,20to100 kHz-max permeation)
Therapeutic ultrasound(mid freq,1to3 MHz)

Diagnostic ultrasound(High freq,>3 MHz).


Magnentophoresis:magnetic field is applied 2 diamagnetic/paramagnetic drugs

bepotastine ophthalmic solution is an antihistamine and mast cell stabilizer for treatment of the
symptoms of allergic conjunctivitis

MOLECULAR MODELLING SOFTWARES


>Chem3D
>Alchemy
>Sybyl
>Hyperchem
>ChemX
>Discovery studio pro
>CAChe

Molecular Modeling Software


AutoDock
Chimera
COSMOS
DOCKclassical
FoldX
Pymol & Molcad
mail at : [email protected] 1
www.pharmacornergpat.blogspot.com

Molecular Modeling involves the use of computer program and algorithm which calculate
structure & property data for the molecule

Dielectric constant:
Mineral oil: 0
Na Oleate: 1-5
CHCl3: 5
CH3OH: 30
Water: 80..

DMSO it is 80

ISOELECTRIC pH
Pepsin: 1.1
Casien: 4.6
Human albumin: 4.7
Urease: 5
Heamoglobin: 6.7
Lysozyme: 11

Ozone gvs strng abs at 254

HPTLC particle size 0.1mm

Solid phase synthesis of polymer demonstrated by merrifield

Solvent in karl-fisher reagent is ethanol

Aurobindo Pharma receives approvals 4 Risperidone tablets,oral solution


&Alendronate tablets 4m Therapeutic Good administration(TGA),Australia

Committee for purpose of Control & Supervision of Experimental Analysis.do such acronyms..
Do all FDA approved 2008,09,10&11 drugs..

mail at : [email protected] 2

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