Integrating laboratory instruments to LIMS to
drive compliance
Steve Hunt, Middle East Account Manager
The world leader in serving science
Integration, Integration, Integration
• We hear about integration all the time but what does it mean for your lab?
• How can integrating your instruments, equipment and systems bring
costs down and help you achieve compliance?
• It’s not just about connecting instruments
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Integrating Thermo ScientificTM SampleManager LIMSTM
LIMS
LIMS
SDMS
SDMS
LES
LES
CDS
CDS
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Complete Laboratory Software Solution
Increase efficiency,
compliance & quality
Save money
Integrate your data
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Paper in the Lab
All manual processes require extra checking & review
ExcelTM Manual Instrument Paper Training
Spreadsheets Result Transcription Records
Instrument Calibration & Paper Reports Standards and
Service Logbooks Reagent Logbooks
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Real World Laboratory Workload
As much as 40% of time is documentation to
support compliance
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Thermo Fisher Scientific - Connecting the Laboratory
Fully integrated solution significantly
reduces manual processes
Lab Execution Instrument Data Data Stability Product Batch Release
Calibration Acquisition Archiving Release Specification
and and
Maintenance Processing
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How Thermo Fisher Scientific Automates
Laboratory Processes
The world leader in serving science
Share Information - Live KPI Dashboards
Dashboards provide a quick view of anything from stocks,
to sample delivery, or trends at a particular location
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Sample Receipt - Sample Tracking with Barcodes
One of the simplest
ways to drive lab
compliance
Easily design and print
barcode labels, either on
demand or on a schedule
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Thermo Scientific Mobile App
Mobile application enables productivity where it’s
needed
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Step by Step Method (SOP) Execution
Step by step
instructions
Barcode
scan
Series of Balance Control progress
Sample weight through the SOP
s capture
13 Minimizes training and enforces compliance
Problem Statement
• Labs have lots of instruments
• Instruments produce a lot of results
• 100 - 1000 a day?
• Manually writing results into the lab reporting system
• A. Takes a lot of time
• B. Has to be reviewed for errors
• C. Is open to mistakes
• All this adds up to reduced efficiency
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The Solution
• Thermo Scientific™ SampleManager LIMS™
• Bidirectional instrument integration
• Download
• LIMS creates a sequence
• Samples, QC’s, blanks, washes etc
• Sequence sent to the instrument
• Upload
• When the instrument has done its analysis it exports a result
file
• Result file is mapped into LIMS against the correct samples
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Instrument Integration - Capture Results Directly
Laboratory Information Management System (LIMS)
Request Test Results Receive Test Results
Data Transformation Link
File/RS232 Chromatography Data System (CDS) MSS
7.25
Gas Liquid Mass
Balance UV/FTIR Chromatograph Chromatograph Spectrometry
Integrate all instruments, not just those from Thermo Fisher
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Integration Manager - 60% of all labs still don’t do this
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Instrument Connectivity Return on Investment
• Automated data entry - no copying from paper
• Elimination of mistakes
• Streamlined review process
• Automatic notification
=
Time Saved Per Instrument Saved Per year
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Result Review - Expedite the Review Process
• Automatic calculations using values collected
• Results automatically checked against stored specs in LIMS/SAP
• Results combined from all systems – CDS, SAP, etc. to provide holistic
view
• Workflows can be used to map out decision
processes
• Automate decision making
• Management by exception
• Initiate actions based on results and
outcomes
• Alert team to non-compliance events
• Drive automatic reporting
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Act on Results - Out of Specification Alerts
Businesses request to
rapidly:
Send for re-test
Initiate corrective action
Produce and email reports
Dashboards can provide visual alerts to
situations deviating from trend or failing
specification.
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What about all your scientific data?
The world leader in serving science
Data Management and Archiving
The problem laboratories face across the globe
Laboratories produce vast amounts of data from a number
of different scientific instruments
MS, ICP, FTIR, UV, AA, LC, GC, SEM.....
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Data Management and Archiving – Some Questions
Inability to retrieve instrument data files
resulted in US FDA Warning Letters for
several global pharma companies
How do avoid FDA How do you collect
warning letters by all these different
How do you
ensuring you can data types from each
centralise this data?
access the original instrument
raw data? efficiently?
How do you share How do you search How do you future
this data? all this data? proof this data?
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Data Management - View data from sample record
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Benefits of using an integrated laboratory
Greatly improved compliance and productivity through
massive reduction in paper and manual processes
Before Implementation After Implementation
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Thank you!
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