4.
7 mg
FREQUENTLY ASKED QUESTIONS
Suprelorin® 4.7 mg is a unique implant that provides a reliable,
non-surgical and reversible alternative to neutering in dogs.
HOW DOES SUPRELORIN® 4.7 mg WORK? CAN IT BE USED IN WORKING DOGS?
Suprelorin is a slow release implant, steadily releasing the Suprelorin® can help manage working dogs, especially when a bitch
active, deslorelin. Deslorelin is a GnRH agonist. The effect is comes into heat.
downregulation of FSH and LH production by the pituitary gland.
This leads to the suppression of testosterone production. HOW OFTEN DO YOU NEED TO GIVE SUPRELORIN® 4.7 mg?
Suprelorin® is designed to last for a least 6 months. The length after
Pituitary Gland
Drug acts here: this varies from dog to dog. We recommend a new Suprelorin®
down-regulation of implant being placed every 6 months to ensure continuous effect.
GnRH receptors.
HOW LONG DOES IT TAKE FOR A DOG TO RETURN TO
Implant
inserted FERTILITY POST-IMPLANT?
here X
Viable sperm production is expected approximately 8-9 weeks post
SEX HORMONES
D E AC T I VAT E D
X FSH and LH recovery of normal testosterone levels. 80% of dogs return to normal
X X
secretion testosterone levels in 12 months, 98% within 18 months. It has been
inhibited
Testes noticed that the duration of infertility post Suprelorin® implant is in
No testosterone general longer in small dogs than in medium and large size dogs.3
production
WHAT TO EXPECT
Onset of action Infertility: 6 weeks
Reduction in testosterone: 9-20 days
Mode of action
Duration of action Minimum 6 months infertility
Return to normal 12 months (80% of dogs)
WHY USE SUPRELORIN® 4.7 mg? testosterone level1 18 months (98% of dogs)
• To trial the effects of neutering prior to permanent surgery. Return to fertility2 Viable sperm production is expected
approximately 8-9 weeks post recovery
• Test the behavioural response to lowered testosterone.
of normal testosterone levels1,2
• For the benefit of reproduction control now, with the option
to breed in future*. Maintenance of effect Reimplant every 6 months
• To still have the benefits of neutering without surgery on high
risk patients.
• May alleviate diseases that are dependant on testosterone (like CAN AN IMPLANT BE REMOVED?
prostatic hyperplasia).
If a client wants Suprelorin® to be effective for only a set
WHAT AGE SHOULD PUPPIES FIRST RECEIVE period of time, then it would be best to surgically remove
when the effect is no longer wanted. To make this easier, it
SUPRELORIN® 4.7 mg?
is recommended to place an implant in an area of shallow
Because Suprelorin® 4.7 mg and surgical castration both lead to subcutaneous tissue - such as just cranial to the umbilicus or the
testosterone levels dropping to zero, the effects on maturity and lateral tibial region. Be aware that the implant may have broken
maturation are the same. Therefore, we recommend waiting until and there may be more than one piece that needs to be removed.
after puberty to give the first treatment of Suprelorin®. Clients also need to be made aware that dogs will take some time
to return to normal fertility
PRESENTATION
WHAT SHOULD I DO IF THE IMPLANT BREAKS?
The Suprelorin® 4.7 mg implant is about the size of a rice grain and
feels waxy. The implant comes in a preloaded needle, similar to a The implant itself is a matrix of waxy material. This is fragile and
microchip. There are 2 individually foil packed pre-loaded needles frequently does break either during implantation, or while it is in the
per carton and one actuator. The actuator should be reused for the dog. This is no concern at all. The implant will continue to release the
second implant so needs to be saved. active ingredient (Deslorelin) at the same rate.
For more information on Suprelorin® 4.7 mg visit
nz.virbac.com/suprelorin or phone 0800 847 222
*
Use with caution in breeding dogs as return to fertility can be delayed. 1. Data on file, Virbac. 2. England, G. and Heimendahl, A. (2010). BSAVA manual of canine and feline reproduction and neonatology.
2nd ed. Gloucester [England]: British Small Animal Veterinary Association, p.19. 3. Trigg et al 2006. Restricted Veterinary Medicine. Available only under Veterinary Authorisation. Registered pursuant to the ACVM Act 1997,
No. A009158. Copyright © 2022 Virbac New Zealand Limited. All rights reserved. Virbac New Zealand Limited, 26-30 Maui Street, Pukeke, Hamilton, 3200. 08/22.
