FMG 100 Most Important MCQ

1. A 19-year-old woman will be traveling to ketone. Which insulin type is most

an area that is endemic for P. falciparum. appropriate for her condition?
She is prescribed mefloquine for
A. Insulin Degludec
prophylaxis. She should be warned about
B. Lente Insulin
which side effect?
C. Insulin Aspart
A. Tinnitus
D. Regular Insulin
B. Insomnia
C. Blurred vision
D. Photosensitivity
A 50 years old male with type 2 diabetes
mellitus is found to have 24 hour urinary
2. Administration of which drug during
albumin of 250 mg. Which of the following
pregnancy is responsible for the picture
drugs should be prescribed?
below?
A. Hydrochlorothiazide
A. Diethylstilbestrol B. Enalapril
B. Phenytoin C. Amiloride
C. Warfarin D. Aspirin
D. Carbimazole

A drug addict patient presented with agitation

3. Patient presented with 6 episodes of and scratch marks on the body. There is
depression, mania & hypomania in last 1 presence of tachycardia, mydriasis and
year with recovery phase in between. hypertension. Likely substance responsible?
What is best drug for him? A. Cocaine
B. Cannabis
A. Lamotrigine
C. LSD
B. Fluoxetine
D. Heroin
C. Valproate
D. Lithium
A patient with hypertension is taking Enalapril,
amlodipine, and triamterene What adverse
4. A 37 year old female presents with
effects might occur with this combination?
hyperthermia, Diarrhea and altered mental
A. risk of hyperkalemia
status. On examination HR=155, Temp-102
B. risk of hypokalemia
F, TSH =0.01 & T4 -12.3. DOC for her
C. risk of hypernatremia
condition?
D. risk of hyponatremia
A. Potassium Iodide
B. PTU
C. Carbimazole Patient underwent surgery. During recovery,
D. Radioactive iodine he was shouting with hallucinations. Which is
the likely cause
5. A 15-year-old female with type 1 DM, A. Midazolam
presents in comatose state. Blood sugar is B. Ketamine
658 mg/dl. Urine is positive for glucose and C. Etomidate
D. Halothane
 FMG 100 Most Important MCQ

Within minutes, she is dyspneic with wheeze,

A patient took some drug for treatment of and hypotensive. Best treatment for her ?
acute migraine attack. After this, he developed A. Adrenaline IV 1mg [1:10000]
change in colour and numbness of the tip of B. Adrenaline IV 1mg [1:1000]
the thumb What is the likely drug responsible C. Adrenaline IM 0.5 mg [1:1000]
and its treatment? D. Adrenaline IM 0.5 mg [1:10000]
A. Dihydroergotamine and Sodium
nitroprusside A 50 year old male presented with complaints
B. Sumatriptan and Sodium nitroprusside of increased frequency along with difficulty in
C. Propranolol and Nitroprusside urination. Which is the best drug to provide
D. Propranolol and Phenoxybenzamine rapid symptomatic relief without causing
hypotension?
A. Tamsulosin
A child is having vitamin D dependent rickets B. Doxazosin
[type 1]. The most appropriate vitamin D C. Finasteride
preparation for him D. Amphetamine
A. Ergocalciferol
B. Cholecalciferol A drug 'X' reduces the static component of
C. Calcifediol urinary obstruction in BPH and takes more
D. Calcitriol than 3 months to exert its beneficial effect.
Which is 'X'?
A. Tamsulosin
A pregnant female presented with burning B. Terazosin
micturition. A diagnosis of cystitis was made. C. Finasteride
Which of the following drug will you use for D. Amphetamine
treatment?
A. Amoxicillin All side effects are seen on long term use of
B. TMP+SMX Proton pump inhibitors except
C. Ciprofloxacin A. Dementia
D. Doxycycline B. Chronic kidney injury
C. Hypermagnesemia
A patient taking alendronate was advised to D. Hip fractures
take large amount of water and remain in the
standing position for at least half an hour. A 64-year-old female with CHF is on therapy
These instructions were given to reduce the with an ACE inhibitor, & beta blocker. She
risk of: presents with severe dyspnea, pink, frothy
A. Cholelithiasis sputum, and diaphoresis. Chest x-ray reveals
B. Constipation alveolar edema. What would be best agent for
C. Erosive esophagitis ?
D. Osteonecrosis A. IV Dobutamine
B. IV Digoxin
A 12-year-old presents with fever, sore throat C. IV furosemide
& lymphadenopathy. She is diagnosed with D. IV Milrinone
streptococcal pharyngitis & given IM penicillin.
 FMG 100 Most Important MCQ

IV furosemide is used for rapid control of B. NitrosoUrea- Delayed BM suppression

symptoms in acute LVF. It provides quick relief C. Procarbazine- Hemorrhagic cystitis
of dyspnea by: D. Bleomycin - Flagellate pigmentation of skin
A. Producing bronchodilation
B. Causing rapid diuresis A patient with atrial fibrillation is placed on
C. Causing venodilation long-term amiodarone. What should be
D. Stimulating left ventricular contractility assessed periodically in order to detect
adverse effects of this drug?
Which is a side effect of Thiazides but not of A. Blood triglyceride, cholesterol concentrations
Furosemide: B. Hearing thresholds (audiometry)
A. Hypoglycemia C. Prothrombin time and antinuclear antibody
B. Hyponatremia (ANA) titers
C. Hypokalemia D. Pulmonary function and thyroid hormone
D. Hypercalcemia status

A 10-year-old girl was brought for excitation, & A patient with resting tremor was diagnosed to
delirium after ingestion of an unknown be a case of Parkinsonism. Which of
substance. Her mouth was dry, pupils were the following is not indicated?
dilated. Her vitals were: T 38.9°C, HR 150/min, A. Pramipexole
RR 25/min, BP 104/72. Best treatment? B. Rivastigmine
A. Atropine C. Deep brain stimulation
B. Diazepam D. Levodopa+Carbidopa
C. Physostigmine
D. Pralidoxime SGLT-2 inhibitors are used for diabetes. All are
side effects except?
The most effective antiemetic for controlling A. Weight loss
cisplatin induced vomiting on day 1 is: B. Fournier gangrene
A. Aprepitant C. UTI risk
B. Prochlorperazine D. Lactic acidosis
C. Ondansetron
D. Metoclopramide Oral direct thrombin inhibitor?
A. Dabigatran
A 60 year old women is diagnosed with CHF B. Warfarin
and it was decided to start the treatment with C. Lepirudin
Digitalis. Presence of which co-morbidities D. Rivaroxaban
would make Digitalis as the best drug:
A. Myocardium ischemia Which of the following is not used as a
B. Anemia emergency contraception?
C. Atrial fibrillation A. Danazol
D. Thiamine deficiency B. Ulipristal
C. RU486
Which anticancer drugs is not correctly D. Levonorgestrel
matched to side effects
A. Doxorubicin - cardiomyopathy Which of the following statements is true?
 FMG 100 Most Important MCQ

A. Drug A is most potent B. Dobutamine

B. Drug A and B have equal efficacy but A C. Noradrenaline
is more potent than drug B D. Phenylephrine
C. Drug C is least potent
D. Drug B has more potency but less A farmer presents with anticholinesterase
efficacy than drug A poisoning. You give him atropine. All of the
following symptoms will be reversed by
atropine EXCEPT:
A. Hypotension
B. Central excitation
C. Muscle paralysis
D. Bronchoconstriction

Oximes are useful for treatment of which

poisoning?

A. Paraquat
Which of the following drugs is most likely to
B. Parathion
cause additive anemia and neutropenia if
C. Carbamates
administered to an AIDS patient taking
D. Organochlorocompounds
zidovudine?
A. Acyclovir
B. Amantadine Which of the following is a direct-acting
C. Ganciclovir cholinomimetic that is used to facilitate
D. Stavudine smoking cessation?

Which anti-retroviral drugs does not cause A. Acetylcholine

peripheral neuropathy? B. Varenicline
A. Lamivudine C. Neostigmine
B. Stavudine D. Physostigmine
C. Didanosine
D. Zalcitabine Which of the following drugs causes Mydriasis
but no cycloplegic action?
An elderly hypertensive has diabetes mellitus
and bilateral renal artery stenosis. The best A. Atropine
management is: B. Tropicamide
A. Enalapril C. Cyclopentolate
B. Amlodipine D. Phenylephrine
C. Beta blockers
D. Thiazides All drugs are correctly matched to their side
effects except
A drug activates D1 and D2 and α1 and β1 but A. Apraclonidine: Lid retraction
not β2 receptors. Which of the following is that B. Brimonidine: Sedation
drug? C. Beta-Blocker: NL Duct Blockade
A. Dopamine D. Dipivefrine: heterochromia iridis
 FMG 100 Most Important MCQ

Enalapril is contraindicated in all of the smear demonstrated P. falciparum. Treatment

following conditions except of choice for this patient?

A. Diabetic nephropathy with albuminuria A. Chloroquine + Primaquine

B. Pregnancy B. Sulfadoxine + Pyrimethamine
C. Bilateral renal artery stenosis C. Lumefantrine
D. Hyperkalemia D. Intravenous Artesunate

Which drugs is not useful in acute attack of All are contraindications for Morphine except?
asthma?
A. Ischemic heart disease patients
A. Salbutamol
B. Bronchial asthma patients
B. Ipratropium
C. Head Injury patients
C. Hydrocortisone
D. Biliary colic patients
D. Beclomethasone

All of the following anti hypertensive to be A 7-year-old child has brief lapses of
avoided in pregnancy except? awareness every 5–10 min. EEG reveal brief 3-
A. Nifedipine Hz spike and wave discharges in all leads. DOC
B. Enalapril in this child?
C. Thiazide
D. Nitroprusside A. Clonazepam
B. Valproate
Digoxin toxicity is aggravated by all except: C. Ethosuximide
A. Hypokalemia D. Carbamazepine
B. Hypercalcemia
C. Hypermagnesemia A 34-year-old man taking citalopram for
D. Hypocalcemia depression wants to stop the drug due to
sexual side effects. He is also trying to
All are True about nitroglycerine except: overcome his dependency on tobacco. If you
decide to change antidepressant, the best
A. It mainly decreases the afterload choice would be
B. It acts by increasing the cGMP A. Mirtazapine
C. Can be used for cyanide poisoning B. Bupropion
D. Should not be given with PDE5 C. Fluoxetine
inhibitors D. Venlafaxine
Which drugs can cause Torsades'de pointes?

A. Quinidine All of the following are expected side effects of

B. Lignocaine lithium except:
C. Esmolol
D. Flecainide A. Polyuria
B. Tremors
A man travelled to North east parts of India. C. Weight loss
After coming back he developed fever, chills D. Hypercalcemia
and rigors and altered sensorium. Peripheral
 FMG 100 Most Important MCQ

A schizophrenic patient started on haloperidol Which one of the following is ineffective in

2 days back, comes with complaints acute iron toxicity:
of torticollis and oro-facio-lingual movements. (a) Desferrioxamine
What is the diagnosis? (b) BAL
A. Acute dystonia (c) Whole bowel irrigation
B. Tardive dyskinesia (d) Ca Edetate
C. Parkinsonism
D. Akathisia An old woman is required to receive 4 cycles of
cancer chemotherapy. After her first cycle, she
Which anti-psychotic is a partial agonist on D2 developed chemotherapy induced thrombo-
receptors? cytopenia. Then in the next cycle, it would be
A. Aripiprazole appropriate to give this patient:
B. Ziprasidone (a) Darbepoetin alpha
C. Clozapine (b) Filgrastim (G-CSF)
D. Haloperidol (c) Eltrombopag
(d) Oprelvekin (IL-11)
A 67-year-old male has been receiving heparin
for 7 days. He comes with severe pain and Mechanism of action of statins is:
paleness of right toe. Hemogram is as shown A. Inhibition of HMG-CoA synthase
below: B. Stimulation of HMG-CoA reductase
Hb 13.2 g/dL; WBC 10000/mm3; Platelets C. Indirect increase of LDL receptors
50000/mm3 synthesis
Which of the following should be used to treat D. Inhibition of intestinal cholesterol
this condition? absorption
A. High dose of Heparin
B. Platelet infusions A 60-year-old male with history of angina is
C. Argatroban hospitalized with muscle pain, fatigue and dark
D. Warfarin urine. Serum creatinine kinase was raised. His
medications include atenolol, atorvastatin, and
A patient presented to hospital with raised ICP aspirin. Addition of which drug precipitated
without intracranial hematoma. Which is the this condition?
preferred drug for the management of this A. Erythromycin
patient? B. Rifampicin
A. Mannitol C. Griseofulvin
B. Prednisolone D. Azithromycin
C. Glycerol
D. Furosemide Nicotinic acid should be avoided in all patients
except
Iron requirement is determined from the A. Patient with peptic ulcer
equation: B. Patient with Gout
(a) 3 x wt. (kg) x Hb deficit (g/ dl) C. Patient with Diabetes
(b) 3.3 x wt. (kg) x Hb deficit (g/ dl) D. Patients with Low HDL –C levels
(c) 4 x wt. (kg) x Hb deficit (g/ dl)
(d) 4.4 x wt. (kg) x Hb deficit (g/ dl)
 FMG 100 Most Important MCQ

A 14-year-old patient is suffering from A. Ciprofloxacin

cryptococcal meningitis. Which of the B. Metronidazole
following Drugs is appropriate to start C. Fidaxomicin
treatment? D. Vancomycin
(A) Amphotericin B
(B) Fluconazole A 28 year old American women plans to travel
(C) Itraconazole to India. She would remain in India for 2
(D) Ketoconazole weeks. Best drug to her for Malaria
prophylaxis?
All are antibiotics active against MRSA except
A. Doxycycline
A. Ceftazidime
B. Daptomycin B. Mefloquine
C. Vancomycin
D. Clindamycin C. Proguanil

D. Quinine
Which drug causes flagellate pigmentation of
skin as shown in the figure? Which of the following is the drug of choice for
A. Bleomycin the treatment of SIADH
B. Minocycline A. Demeclocycline
C. Vincristine
D. Daunorubicin B. Tolvaptan

C. Thiazide diuretics

D. Desmopressin

A 37-year-old man is diagnosed with colon

adenocarcinoma. The oncologist recommends
the use of bevacizumab. This agent
All of the following antibiotics are safe in a A. Blocks intracellular signaling by EGF
patient with Serum creatinine 2.5 mg/dl except B. Inhibits cell cycle progression
A. Doxycycline C. Induces differentiation of cells
B. Rifampicin D. Inhibits angiogenesis
C. Ceftriaxone
D. Imipenem
A 45 year old male with NHL is being treated
with CHOP regimen [Cyclophosphamide,
Which one of the following drugs is an
Doxorubicin, Vincristine, and prednisone]. He
antipseudomonal penicillin?
develops hematuria and suprapubic pain.
A. Cephalexin Which is the most likely causative agent?
B. Cloxacillin (A) Cyclophosphamide
C. Piperacillin (B) Doxorubicin
D. Dicloxacillin (C) Prednisone
(D) Vincristine
DOC for treatment of Clostridium difficile
associated diarrhea ?
 FMG 100 Most Important MCQ

During treatment with ABVD regimen for Hemodialysis is useful in all except:
Hodgkin lymphoma, a 50 yr old male
A. Barbiturate poisoning
developed dyspnea, and cough. X-ray revealed
B. Methanol poisoning
pulmonary infiltration. Which is the most likely
C. Salicylate poisoning
causative agent?
D. Digoxin poisoning
A. Bleomycin
B. Dacarbazine
C. Doxorubicin Which of the following act through G protein
D. Vinblastine coupled receptors?
a. Muscarinic receptors
A 42-year-old premenopausal woman recently b. Insulin receptors
underwent partial mastectomy for a small c. Nicotinic receptors
tumor in her breast. Post surgery, the d. GABA receptors
oncologist recommended tamoxifen. Which of
the following is a serious side effect of
tamoxifen? Drug acting via tyrosine kinase receptor is :
A. Thromboembolism a. Ondansetron
B. Bowel perforation b. Vit D
C. Aplastic anemia c. Insulin
D. Myelosuppression d. Adrenaline

A 56-year-old man complains of fatigue and A 60-year-old man being treated for
malaise. His white blood cell count is Rheumatoid arthritis comes with progressive
dramatically elevated. Chromosomal studies visual loss. Fundoscopy revealed a concentric
indicate a (9:22) translocation, the Philadelphia zone of hypopigmentation as shown in picture.
chromosome. Which is to be used in his Identify the cause?
treatment? A. Chloroquine induced retinopathy
(A) Dasatinib B. Methotrexate induced optic nerve
(B) Rituximab atrophy
(C) Imatinib C. Infliximab induced optic tuberculosis
(D) Gefitinib D. Optic degeneration in RA

Rituximab is used in all except

A. Non-Hodgkin lymphoma
B. Paroxysmal Nocturnal hemoglobinuria
C. Rheumatoid arthritis
D. Chronic Lymphocytic Leukemia

Drug of choice to treat hyperthyroidism in

Loading dose depends on all except pregnancy
A. Drug concentration to be achieved a. Radioactive iodine
B. Volume of distribution b. Sodium Iodide
C. Clearance of the drug c. Carbimazole
D. Bioavailability of drug
 FMG 100 Most Important MCQ

d. Propylthiouracil D. Increasing renal excretion of uric acid

Contraindication for the triptans is? All are TNF-a antagonists used in rheumatoid
arthritis except:
A. Ischemic heart disease
A. Tocilizumab
B. Pregnancy
B. Infliximab
C. Uncontrolled hypertension
C. Etanercept
D. All of the above
D. Adalimumab

Drugs used in migraine prophylaxis are all

A 50-year-old female with RA is going to
except-
receive infliximab therapy. Which tests should
A. Flunarizine be performed before beginning treatment?
B. Propranolol A. Liver function tests
C. Amitriptyline B. PPD skin test
D. Sumatriptan C. Pulmonary function tests
D. Visual examination

Rofecoxib was withdrawn due to: Treatment of choice for late cardiovascular
A. Ischemic heart disease syphilis is?
B. Renal complication A. Benzathine penicillin 7.2 million units in
C. Liver adenoma three divided doses
D. Gastric ulcer B. Benzathine penicillin 2.4 million units
single dose
Drug that requires dose reduction when used C. Benzyl penicillin 12-24 million units for
along with Allopurinol is 21 days
A. 6-Thioguanine D. Tetracycline 2g daily
B. Azathioprine
C. Methotrexate A patient presented with hospital acquired
D. 5-FluoroUracil pneumonia. On testing he was found to be
allergic to penicillin G. which of the following
Which of the following can not be used for drug is likely to be safe in this patient?
acute attack of gout a. Methicillin
A. Colchicine b. Cefotiton
B. Indomethacin c. Imipenam
C. Allopurinol d. Aztreonam
D. Dexamethasone
A 53-year-old man is scheduled to receive
Rasburicase is used in gout. It act by: vecuronium as a muscle relaxant during
A. Decreasing urate synthesis abdominal surgery. The dose of vecuronium
B. Increasing urate oxidation may have to be reduced if this patient is also
C. Decreasing intestinal absorption of uric receiving
acid a. gentamicin.
b. penicillin.
 FMG 100 Most Important MCQ

c. ibuprofen. A. Paroxetine
d. acetaminophen B. Valproate
C. Warfarin
All of the following conditions get worsened D. Lithium
after timolol maleate 0.5% administration
except:
a. Bronchial asthma
b. Hypertension
c. Depression
d. Diabetes/Glaucoma
Which Antiglaucoma drug causes the side
Which of the following is a true statement effects shown in picture?
regarding Aliskiren? A. Timolol
A. It is contraindicated in diabetes mellitus B. Prednisolone
B. It can be given in pregnancy C. Latanoprost
C. It increases the aldosterone levels D. Apraclonidine
D. It indirectly Increases renin levels

Which of the following is safe in cirrhosis of

liver:
A. Lorazepam
B. Chlordiazepoxide
C. Alprazolam
D. Diazepam
A 59-year-old man presents left ventricular
infarction. He is given all drugs below. Which
Which should be monitored if linezolid is given
drug provides immediate relief but does not
for more than 14 days?
reduce risk of sudden death from another MI?
A. Liver function tests
A. Aspirin
B. Kidney function test
B. Atorvastatin
C. Platelet count
C. Propranolol
D. Audiometry
D. Nitroglycerin

A female presented with burning micturition Sugammadex reverses the action of

and symptoms of UTI. Which fluoroquinolone rocuronium by interacting directly with the
is least likely to be effective? rocuronium molecule and not at all with the
A. Ofloxacin rocuronium receptor. Which best describes
B. Moxifloxacin this interaction?
C. Ciprofloxacin (A) Chemical antagonist
D. Levofloxacin (B) Noncompetitive antagonist
(C) Pharmacologic antagonist
A 30-year-old mother with h/o psychiatric
(D) Physiologic antagonist
illness delivered a child with atrial septal
defect, abnormal tricuspid valve and a small
right ventricle. Which drug may result in such a
deformity?