Experiment = 4. _
“Te prepare and submit” paracetamal paedis
“Elinte fF. Se iia lad oad it
Reference: Sanmathi BS Mehta KK Aon
wpe oaual dupa pny
_ edition, Phar p. Sa fderabad. “i
Pg No. 46 to 44
_ i Prop tne 9 col is
used asa co- solvent ,to ineréade the
| olubitity of paracetamo.
“Therefore to mask this taste, invert
s Yis_
pn ee aan al sgt aac
por pte,
[ e, © Glycerine _is used to increose the vi cosity
—__| of the prepa ration and also acts ag
——Thumectant and gives soothing effect.
i =
Teacher's Signature :__k
R
Paracetamol
Ethanol (46 7.)
Propylene Glycol
Conc. raspber juice
Chloroform spirit
Invert Syrup
Amaranth solution
Glyeriny.. qs:
Fiat: Elixiy
gr xxxvi
f1.3 iiss
FI.3 tiss
M xxxvil ss
M xxx
RL.3 vit
M iti
Fl.3 xxv
Mitte: fl.oz ij
Signa: Cochleare minimum mane et
hocte capiendus.
Type ‘Ingredients Raed was hea fe Rept
imperial | Metric | patient | in tab
Paracetamol 36 ay aby Heute g | 0.48
Mono- | Ethanol (961) 2B Ady! tom | 6 mt | 2m
‘ phasic | Propylene Glycol | 2:5 fdr] tom | 6 mi aml,
ie ee Conc Taspberry Juice! 34-5 Mit 2-5 wat} 65 mt | od ml!
Chloroform Spirit | 30 minim gan) Lom | o& wl
Trvert Syrup Tidy | og mp | tg ml 5.6m
Arnaranth solution! 3rninim) eg ml | 0.12 ml | 0.04"
Glycerin. qs. [85 Fld lOom! | 60 ml aot}
Make: Elixir Send: Go ml
Direction: One ce to be taken, mornity |
4Procedure: DAccurately weigh the paracetamol! and dissolve
_— tn_measured queintity of alcohol C961.) and
propylene o Hlycol. eae
___@To “the above mixture ,add chloroform spitit
invert jar and concentrated raspberry juice
wwoith stir - sane ne! audit
—__ @ Transfer this content toa measure, add amaranth
___ solution and make up the final volume with glycerine
___ @Filter if any foreign particles _or any ——__
ss “undissolved ‘subst@nces Tas ere Lenk on
Dispensing: Transfer the elixir toa light resistant,norvow
Dispensing) sistant n
— mouthed, glass bottle, se it ti ghtly with |
metallic screw cap, polish ound * lobel,
dt - - - 7
Direction: One teaspoon to be taken, morning ond night:
Storage: Store in_a_cool place aR ha ae
Lobel : Label must bear all necessary requirements of liguid
dosage forms ,meant for internal use. In addition,
a TtheYamount of alcohol content used in the ——
7 “preparation shouldbe “mentioned on the label.
Use, Parocetarnel pacdinbric elixir [_used_aa—
Sos fan analgesic and antipyretic for_childeen.* Conversion factors»
tion facto
@ 1 fluid dracum = 4 mI
@ ts grain = 4 gm
® 15 minim: 4 ml
4
@ 4 Fluid 02 = 30 ml.
* Lobel:
Paracetamol poesiorris Elixir I. P.Qoml)
Paracetamo|
Ethanol
Propylene Glycol
: 1 046g
2 ml
ami
Conc. raspberry juice : 0.5 ml
Chloroform Spirit
Lrvert suv
Amaranth solution
Glycerine -q.8:-
‘Lie No.: Aor
Batch No: ol
iMrp: XXK
10.4 mi |
6.6 ml
2 0.04 wml
+ 20 ml |
|
pH
MPg Date: 20-09-23 |
Exp Date: 20- 0g- 24 |
Store in a cool. “Place.
‘Direction: One teas Poontyy
| Use: Analg esic an
rerning rae af be taken, |
anti
My by Stisha bate \Pyretic fo children
Mfg Hep Maliba har
Gnd Krishi Patel. |
matey College, Tarsndi© xperivnent-2. ave
‘To prepare “end “submit simple symp.
Reference: Sanmathi_|
BS,Menta kK ,Gupta A, D jspensing.
ph +O practical manual, 37% rd edition,_
Pharm Med Press. Press, Hyderabad , Pg No. 100 _to (Ol.
fice Sica sy trated or nearly — 2
__~__ saturated “solution of Sucros oce_in purified Gattr.
Tt contains 66.4: wlus of sucrose. tence the solubilis
en lS rose, $ rm cae he ati
a Sucrose is @ cara pared whi ch partially
____ hydrolyzed i a a iainemealr tae feewere
uct) apd lappa Boece nies ee
_dive _catled nd_rtaction is —
catled as “Inversion”
4, ator tal
— Teta 2 Dyce HO 9 Cet Og t CoH yy Og
__ Sucrose Dextrose Laevulose
— the inversion of sucrose is confirmed by __
i ppeasearin its optical rotation. After inversion, if th
—_ leplution of sucrose rotates the polarized light to
“he right side, then it is considered _as “dl exteo -
lyotatery, If same solution rotates the
- polarized Light to the left side then it is
considered as (evo -rotatory.R
Sacchart
Aquam q:s-
Fiat: Syrupi
Type, Tngredtents
More : iomenoee
liquid for
pharmact| Purified water 126 fidr
atic
|
Make: Syrup
3xvisss
3 xxv
Mitte: flioz ij
Quant ity Guinntity Quontity duanty
i
1 taken by! p mar
| imperial! ¥ metric patient! te ab
Tt
16-45 dy | 6tg A0.2q 13-4
(00 ml] €o mI | 20 ml:
qs ;
Send: 60 wl.Procedure +O Accura weigh sucrose and olissolve in 2 of
total volume of purified water ino beaker.
_@Heat this solution on a water bath with occasional
Stirring, until whole amount of sugar completely
____dissolvés.(Do not do overheating) ————
____ @Allow the solution tocol a Filter through
___ THe muslin cloth, to xtmove fortiqn. articles ,if—
| pre seb
Dispensing > Syrup “shou id_be always dispensed in do _bottles,_|
___ becaus e¢ Moistire coritent present in the wet —_
‘pottle is sufficient to cause Fermentation.
After preparation of syrup _it bould be cooled]
7 z room temperature, before Filling into the bottle
a ce if ayup filled in to the bottle, it should be
occasionally shaked until, hat attains room temperate
Because moisture will condense or th inner side_o
anes | pper part of the bottle These water molecules after
a _Lrunning down, dilute the upper layers of the syrup,
which Leads to fermentation of sucrose a
: “Therefore transfer the symp to a well dried, —
| neerrow_rnouthed, amber coloured, well Fil
_bottle , close it thoroughly wi th plastic screw cap,
nee! polish and label
Sag fa agp le poapased_on_legaquntily then it
aig! aaa ath eoatoned int loosely stoppertd _
— bottle, because plese entation takes place Carbon
ioride oill liberate, pohich i rect# Conveuion factors *
® 1 dvacuum = 4 qm
@ 1 fluid dracum = 4 ml
@ 4 fluid.oz - 30 ml
¥ Lobel:
ee
Sirmple Syrup 7-P —
Sucrose (3.49
Purified water..q.s
‘Lic No. : Ado!
[Batch No: 02
i x
xo ml
|
MFg Date: 24-09-23
|
Exp Date: 24-09-23 |
|
|
[Mrpixxe |
[Store in a dark place ,at 25°C .
|Use: Pharmaceutical aid.
Mfg by : Misha Patel
Mfg ot: Maliba Pharmacy College ,Tarsadi.— inside the_bottle_and mes “leads to bursting
of container (ee J
— Warm f lace favours the Permentation and
C00 ol place induces s alization, therefore synus
Teneo “Phir uy cant bap eratue ie
| —trceeding 26°C 41 ae
‘Auiiliany + STORE AT FAIRLY CoOL TEMPERATURE ,NOT
label” EXCEEDING #5°C IN DARK PLACE.
Uses 5 Simple mup is used os a pharmaceutical aidl, i in the
__ preparation of many pharticeutical products for the!
| Following rem songs
Tt has plaice sureet taste. Hence itis used as o_
Te ad aaiguoucabstageen
| _ bitter az
7 @ Itis alco used aso vehicle for many ti liquid |
! oe ee ee a ec pe
__@ Ins sucrose undergo hydrolysis into reducing sugars, as)
__idextrase and Levulose which acts as anti-oxidants: Hence sy raf
reduces ths ation of ee ee hpi
___|sufficient. be vec ceceiatave Dementia
_osrnotic pressu. eit withdraws water frm the
ricroor pele ood tends Ht dehy den
__| finally death of microorganisms it_acttas
Sq ot preservative" _ oa
Teacher's SignatureExperiment 3.
Te prepare and | A supp ly piperazine citrate —
DATE
finns: Sanvonta Bs _,Mehta } K K strap. A — Dispensing —
— ohana. Med Prees Hyderabad Pg No. #4 to 5.
Theory : Piperazine citrate acts acts ag anthelmmmtic. It
__~isin salt form ond hence freely soluble in water.
Therefore it doesn't requi € Qmount of aleshel
The alcohol Which ig present i Spiti
_ enous are h -alcoholic i
y in itrate - \ pirit also act aa
preservative:
2 | Glycerin act$ as a _co-Solvent to enon e the
—___solubi of dru vi fect.
ao | iPerazi itr i
a 6 ; tu i Le and flav
lagent like orange oil art used Yor masking the
Lun pleasant taste:&
Piperarinae citratis
Spiritus Chloroformi
Glyerim
Olei auranti
Syrupi
Aquam-- 4S
Fiat: Elixir
Signa: Cochleare mi
% ivss
M viit
£).3 iiss
ae
£1.38 xiiss
f).3 xxv
Mitte: fl.oz
nimum duo nocte Sumendum
Type Ingredients
Cuontity| duastity) Cuontity [Gusti
— im 7) in Haken b ory
imperial) metric | pati in [ab
Mono- Piperazine citrate
plasic Chloroform spirit
Htiquid
\for oral Glycerine
u.bdr | 18g 5.44 3.6 9 :
g minim 0-5ml} 0-15 ml Oot mal
26 fdr} tOml| Seat | rl
| use 0 nil |
| |Oran \ 1S. +S. 18s BI
easel Onenaect! (ance ides Ja esate
pouaple syrup 12-5 £ldrl 5oml| tS ml | (Om
| Purified ee 25 fldr| l00 mt] Jo mt | 207! I
"Make: Elixir Send: 30 ml
“Direction: Two teaspoonful to be taken at nighProcedure: OAccurate eis aa eine FT
dissolve im alte igh the pipetntine citrate card 4
: OF purified woten —____
i -@ Dissolve oran e oil in chlornform spiritand odd tothe
_ piperazine citrate solution, mix welt
____@ To the above soluti i
ution,add simple syrup ond —
_—glyceriny mix_uniformly. Th isconttnt to o
__ measure ioind:adjuat the Final volume: twith purified user
Dispensing: Transfer tae elixir to lig 4 resistant nor roi mouthed
___— glass ttle, close ik tig htl { etallic screw
top, polish and lobel
Dose _ ‘for treatment _of round worms, asa single lose up
th f \ cco 0. i £
for children + 4-12 A ee eta ad
2 40.3 years = 5 ml
| 4 to b yeors = 4.5 ral
— [Econ 4 to 12 fears = 1o ml
For treatment of Thread worms, 4 to 15 ml _
— daily in divided doses i given.
Direction : Tusa teaspoonful to be taken, at night.
Storage. : “Store ina cool place,
re lee - ane
Uses |; Piperazine citrate expels Hae round worms
—__ thrtad worms fim the intestine therfore
tae elixir is Used os anthelmintic:
|
jeacher’s Signature¥ Conversion factors
@ 1 dracum = & gm
@15 minimse 1 wl
@1 fldy >
¥ Lobel:
uml
we
Piperazine Citrate Elixiy IP. |
Piperazine citrate 3.69
| Chloroform spirit 0.t ml
| Glycerine 2QmI
| Orange oil q:s-
Simple symp loml
| Purified Water-q.s-- 20 ml
|Store in @ cool place.
Direction: Two FeaspoonFul to be taken
| at ni
Use: Anthelmintic
[Lie No. + A0ol Mq Date: 24-09-23
fl
Batch No.:03 E 24-09-
Imig: ee xp Date: 2-09-24
Mey by Misha Patel
Mfg a :Matiba Pharmacy College, Tarsadi.
ee aones
prepart_ond Sie
Tes -- | submit Aqueous ==
water im presence of potassium iodide.
____ Because Todine reacts with potarsitim—
_ ——todide cuncl_Pornas_comele ex called au
sl polyiodides A “These polyiodides pleas
Lil
a stable iodine ine
KI +1, —— kKr.1, ( Potas ita monoiadide)
___|Ki + +21, ——> KL.21, (foto
[er + tal. — —— KL. at, (Potassium tri iodide) |
> KET, + KD2t thE BT KL. nl
Ho Ke tn TY
| Potassium +Todine Polyiodi ided
Eee fodide
Hi her pol ‘iodide: are more Soluble than |
epee Polyiedide Therefore to aet higher
= [poly iodides» ithe comnce nitrated solution {
— prepared boy dissay) iodine and
ide_im small portion of
| water, then it is diluted ‘with theTodi
Potassi lodidi
Aquom...q.s
]
Bis
Bitss
£3 RXV
Fiat: Liquor Mitte? Plozi
Signa: Cochleare amplum, omni
nocte sumendum.,
j Type redients Ouonti ty Quantity Cuanti ty Quant
[at tng | imperil mebric fakery! haa
otytion| Todine 125 dy 5g 154 14
wwe) | [Potassium iodidel 2.5 dr (og 34 24
oe Purified water 25 fldr) |
| es OO ml} 30 mi} 20 ml
eee
Moke: Aolution
Djrection | 1 fend: 39 me
Bigna ne tabled poonfus
every wight ut to be taken af
Eeefeature Weigh separately iodine ond polassium di
Triturate . : , :
one sHedine into Pine ponder in o.glass—
®Tn Oo benken, dissolve potassium iodide
ae portion of water To Hau solution
& wot lQaseaodiet
Wien eae
Telus ain al[Aqueous “Lodine Solution I.P.
LAG OOK
Todine tq
| Potassium iodide 24
Purified water gS: 20ml
lic No: Aool Mfg Date: 1-10-23
Bateh No:04 Exp Date :t1-19-24
[Mrp: xxx
[Store in a cool and dark place.
Use: For treatment of goitre.
MPg My Misha Patel & Notnrahtel.
Meg Oo ‘Maliba Pharmacy College Tarsadi.
iret: One tablespoonfur
enot evel A
to be
bd.el s o - ye UAE nsteaol
muUdth, bu the py idotion or
alogenattem off pets 8 veel protein a
NOTE: © Todine staina a1 brown colour on
the—skin, cloths ond containers mode up_
oh Pc eloin ond | metals. ae
al
tod Ln pent. Tt
| oxidizea irom Conv
tod .R
xx vlis
Citric acid monohydrate qr x S
Concentrated amise woter qt ‘ett ss
Uquor amaronthi ee
Chioroformi Spiritus pied ew
Syru pi “QS: . .
Fiot: Linctus Mitte: floz.t
Signa: Sip, Cochleave minimum et
degiutiendus tente, bled.
TT 7. ; se] 7 .
Type | Ingredients Quantity Cuaartiy Quantity earl
L imperial | metric poati lob. |
Citric. acid SES are . A |:
Honophai monohydrate (Sq) 2-59 | 0.459 | 0.59
jar oal Cone-amise water [5 minim 1m | O.3mt} o.2ml
VAC Amaranth solution 22-5 minim (5 ml
| 6.45 ml} 0.3 ml)
iChloro form spirit |
[1 minim, 6 mat
{Sirm ple ogre 25 Sly) too mt
|
|
L&mt | tam
Boml| 2oml
| Make: Linctus oul Boul
‘ |
BignaDirection: Sip, one teas |
| slowly , tuo Firmen a oy supasloy
ooCpeniens e
— DATE
SS
To prepare a)
f Prep tnd subnit simple tinctus BPC.
Teacher's Signature —® Conversion factors:
@1s gre
@ 15 minim 24
@ | thedr= & wy
* Label:
| a ID)
- Simple Linctus Bec. |
Citric acid monohydrate 0.5g
Conc. amise water 0.2m) |
Amaranth solution 0.3m |
Chloroform spirit 1.2 ml]
Sirnple SYMP--Gs-- 20 ml
[Lic No: Avot Mfg Date: 1-10-23
patsuNes 05 [Exp Dote: 11-10-24
Store in a cool and dark place. |
DO NOT DILUTE WITH WATER
Direction: Sip, one teaspoonful and
oo ees sloubigy buss iy
| Use: For treatment of cough.
Mfg by : Misho Patel 2 Namra Patel
mg at : Maliba Pharmacy College Tarsad iDATE
se Troms Pen he ae to a norrow moutted,
aes eA Stant, gloss bottle, clede —
+ Sagal wits smetallio Acre Cae
peluk" ard label,
se S_po0ny tt and swallow asl
nach d tore in aco oA potted Tre i
lay ST TORE IN_A COOL AND DARK PLACE.
Lobel's Do NoT DILUTE WITH wATER BEFORE USE:
tBimple linetis is uted os demufeent
= +h ector ont in the treat nremt of na
- wenn
Toachor's Signal;Experiment 6
DATE
ar =
cop dispense “ce eened watts
Eevee le ca
poo: 4 4 7 bee e|
boadul? Dissolve potassium hidroxide in Vy te
A af ed AD OL PH» ‘
Teachers SignatureR
Cresol 1.3 iiss
Vegetable oil A..3 ivss
Potassi hydroxidi 3 i
Aquam
[email protected] [1.3 xxv
Fiat: Liquor Mitte: floz it.
Signo: Utendus, more dicto.
—— uantity | Quantity Cuartt ty) Qusst
| 7 dients a
GP | green Hinapertadl| ncebtte,|* patie | ‘nctas
(2.5Pldr 5 lo ml
Pie Cresed oml| 30 ml
jor | Ves etobte ol 45 Play (8 mi | (0.8 wal) 30m
eee
Mettler | 49 Joey] ota,
| | Purified iceter 26 Pld (OOm!| 60 mi Do wil
|
og etek Salat i
Make: solution Send: bom -
| Direction: “To be uled, au dinected .
eteaid. meal i ;
the oboe mixtire Got Hh Prieta «|
Ativrina |
(Add tM ia 4 Content to Cu meat |
—_| On At uLA Fin ok v Otte I
ae [
if
: eects Sirota Ee" SLOAN¥ Conversion Pactors :-
1dre 4
4 fidre G ml
¥ Lobet:-
=
Fare |
_Cresol with Soap Solution. |
| Cresol 10 mI
Vegetable oul 3.6 mt
Potassium hydroxide 0.8 g
Purified water, 9.5. 20 ml
‘Lic No: Aool (MPy Date:18-10-23
Batch No. 06
I 5 -10-
Mrp oxen, Exp Daterig 10-2
Store in a cool place.
For EX TERNAL USE ONLY.
Direction: To be
Use: As a disin
Ffectant,
Mfg by :Misha
Wed, a4 directed.
Pater & Monn Patel
Pharmacy Colleg eTarsodyy, FOR EXTERNAL US ONLY
an tL US
and hence camatic in Nord.
tissug it.
uk Co taed 1A_O a tae ot ortho, acta
3
i438 pecrotic_actian to Onimal tissug it -
Ahold net be ued as Gmetinpee for
Heir otn beings
‘Teacher's Signature
LeExperiment <7.
vi te aE A
— leotution are tused eaaare otis
, bi b ic if
| icjent for complete nektralization.
leh aciol acetre Acid , ae tod at F
; ——— Teachors SignatureR
Glacial acetic acid
Ammonium bicarbonatis ms
Ammonium strong solution K1.3 ss
Aquam qs FILB xxv
FIL3 Kis
% x 1s$S
Fiat Liquer Mitte: fl.oz i. i
Signa: Cochleare amplum, bis indie Sumendum,) >
Quostity Quast
el mibric ate intab
‘Glacial Acetic acid | 11.25 Play 45mt) 2tmetl On|
Aclution Ammoncunmn, | [.
en bicarbonocis ae utg 829 449),
uit Aromonie trong)
Avution d 25 Far} Lomt | Gamat | 9 wl (
Punt pitel usoten | 9 | I
5 fl. I
Ban shies Fade 100 my 380 ml Lol”
|
| Make: Aelution is 5 ae
t . Om.
| Dirtetion OfagePlespoon tusDATE
H Co, 00
a > tH, ,COONH,, tH 0 +60."* Conversion factors: cee
OLdr= y
O 1 Fide Gynt.
'
¥ Labet:.
‘Strong Ammonium Acetate Solution I.P.
GlacioP acetic acid Im
Aramonium bicarbonate qu g
Aromonium stron Solution
d2™|
Purified water, PQS... 20 mI Z ;
lic No:A0Ol MPg Date: 18-10-23,
[Batch No: 0% Exp Pate: 18-10-24
Store in a cool place. 7
| Dyertlon ome tablespoonful to be taken twic
Le aus ;
a
A ee AS a diaphoretic and expectorant,
Meg by: Misha Patel 2 Mann Patel
| Mf at: Matiba Phar
gees Pharmacy Celege, Taree,—2) Bre mothymel blur Givtsa— L
-6~> -4£
b) Thana bles gies
Yollour ot pH — Blut ot p= 1.6.
Bromothymel blur indicates (ower
link p= 4-6 and blue
| tr_linmat YpH-§.0-
Neutra Lizobi th | paint exis between _
[oH 4.6 bo £0 re pH LA mradntainedDATE
giaciod Pat acid with continuo
can ts ae
ee
a
Uses
~_|
~_|r
R
aL xXx
Soclii chloridi i i
Sodii bicarbonatis
Liquor amarantis “on x
Aguam menthae piperitae qs: fl.oz. x.
Fiat? Collutorium Mitte: fl.oz fi.
Siqna*% Cum duplo aqua calidae aequoles, fn,
Ulendum et rinse oris omni mane.
se li
Tupe | Ingyedients | [Cupatity Quantity] Cuontity used
yp dd inn \Berial ae iene tre ty
M ; jar 40 Aodium chloride Boqr | 5.3 B.l@q | 0.35
Tonophu J 9 J J
usedonly Sod (ual vtl 40 gr 2.69 [-569 0.149);
in mouth | r
or buceed Amaranth (50minim) 3.3 ml} [98 wt} 0-22 mI >
cov iby. Solution [
Peppermint) 10 Fz 300ml} 60 mI | 20m!
WOttr---q-S-
|
elk
Make: Mouthwaih Aend: bo Conall
frection: Dilute With an rel of
aaere wattr, before neva vine ta oi
Le every ” morning. tha ™
——_———-
er ys | LP UAT
aaExpuriment-§.
o ane a
- Ond dispense com ound
Sodium chtoride mls ee angen spc :
foe: Aonmotai Bc, Mehta Kol pel k., Anchu :
Gupta, Dispensing pharmacy -a practical
_—-manuol, 374 edi : med press,
_—_ Hyderabad ‘ Pg no. 119-120 —
feory: Tk 1s 0 mouthwosh containing sodium
1 i e, sodiumw chloride ata Sodium
bicarbonate. Soditim chloride actt os
| mM ion
ou
eon PAE TRToeT ER rere
= eodorant antaci trols pH) & ie
lone iL, stir lei _pep
watth henrte mouth wash ts pre parcal
bu im ple olution method
J . 5Spe pepe wood Fo
oa Ott the “tinal valu oa or
+t ote
Saree pottte close pear a FST
_ iat plastic Screw Cap ;
sn im a _coet place
* FOR ExTERNAL USE ONLY
*NoT To BE SWALLOWED, IN LARGE
@UANTITIES.
seat Compound sodima chloride naouth wail
“ite aed to clean and deodorize Uo.
buccal covity. Tt ia ae! used tp