All   C       opyrig
eR
                                                                                                                                              ht
              CLINICAL APPLICATION                                                                                            ech
                                                                                                                                 te
                                                                                                                                                 by
                                                                                                                                          vo
                                                                                                                                            rbe
                                                                                                                           Qu
                                                                                                                                               ha
                                                                                                                                nt               lte
                                                                                                                                                    n
                                                                                                                             i
                                                                                                                                      e ss e n z
          A Novel Technique
          for In-Office Bleaching with a 6%
          Hydrogen Peroxide Paint-On Varnish
          Antonio Duarte Sola Pereira da Mata, DDS, PhD
          Associate Professor
          Oral Biology Research Group, Instituto Superior de Ciências da Saúde Egas Moniz
          Monte Caparica, Portugal
          Duarte Nuno da Silva Marques, DDS
          Assistant Lecturer
          Oral Biology Research Group, Instituto Superior de Ciências da Saúde Egas Moniz
          Monte Caparica, Portugal
          Correspondence to: Prof Antonio Duarte Sola Pereira da Mata
          Instituto Superior de Ciências da Saúde Egas Moniz, Oral Biology Research Group, Campus Universitário – Quinta da Granja,
          2825-511 Monte Caparica, Portugal; phone: 351 91920 6396; fax: 351 28970 7564; e-mail: 
[email protected].
70
THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                       All   C              opyrig
                                                                          eR
                                                                                                   ht
                                                               MATA/MARQUES ech
                                                                               te
                                                                                                      by
                                                                                               vo
                                                                                                 rbe
                                                                                   Qu
                                                                                                    ha
                                                                                      nt              lte
                                                                                                         n
                                                                                     i
                                                                                           e ss e n z
Abstract
In-office techniques for bleaching vital teeth   study. Ten-minute applications of the paint-
are effective and expedient, but because         on whitening varnish were performed re-
they require the use of elevated concentra-      peatedly with each patient for up to 1 hour
tions of hydrogen peroxide–based agents,         and then repeated 1 week later. Initial
which are caustic and potentially toxic, they    shades were recorded with a Vita scale
are found to be less appealing by practi-        guide, and photographs were taken at the
tioners compared with home whitening             beginning and end of the study. A ques-
procedures. In this article we propose a         tionnaire assessing clinical parameters
new technique for in-office whitening of vi-     and patient satisfaction was performed.
tal teeth using a 6% hydrogen peroxide             A change of 7 to 13 values on the Vita
paint-on whitening varnish, which enables        scale was observed in all cases. There
the whitening procedure to be more eco-          were no reports of tooth sensitivity, and
nomic and user-friendly, as well as less         overall patient satisfaction was achieved.
toxic and time consuming, compared with          In-office bleaching with the use of paint-on
traditional in-office bleaching.                 varnishes seems to be effective, safe, and
  A total of six patients with no caries or      well accepted by patients, offering a viable
restorations in the maxillary and mandibu-       alternative to high-peroxide-concentration
lar anterior teeth were selected for this        in-office procedures.
                                                 (Eur J Dent 2006;1:70–77.)
                                                                                                        71
                                                         THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
                                                                         VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                                                     All   C   opyrig
                                                                                                        eR
                                                                                                                      ht
             CLINICAL APPLICATION                                                                         ech
                                                                                                             te
                                                                                                                         by
                                                                                                                  vo
                                                                                                                    rbe
                                                                                                      Qu
                                                                                                                       ha
                                                                                                         nt              lte
                                                                                                                            n
                                                                                                       i
                                                                                                              e ss e n z
          Over the last two decades, patient demand                   sion up to 30 minutes. Effective bleaching
          for esthetic dentistry has increased dra-                   is expected in 2 weeks following a twice-a-
          matically. Having a beautiful smile has be-                 day regimen.
          come an important part of a successful so-                      The low peroxide content, elevated per-
          cial and professional life for most people.1                oxide kinetic release, and short application
          When tooth integrity is acceptable, dental                  time associated with these products sug-
          whitening procedures represent an easy                      gest that they may be a viable and effective
          and viable option for attaining a patient’s                 alternative for in-office use with far lower
          desired smile.                                              toxicity potential compared with traditional
             In-office bleaching has the longest his-                 in-office procedures.
          tory of all the tooth whitening procedures;
          the process can be traced back as early as
          1877.2 Since 1989, when the nightguard vi-                  Method and materials
          tal bleaching technique was introduced,
          home whitening procedures have become                       A new 10-minute in-office multi-application
                                   3,4
          extremely popular.             Nevertheless, the use        technique employing a 6% hydrogen per-
          of several in-office techniques is still wide-              oxide paint-on varnish (Paint On Plus,
                    5
          spread. The convenience of the in-office                    Ivoclar-Vivadent) was used to treat six pa-
          techniques lies in how quickly the desired                  tients in two 1-hour visits.
          results can be obtained. Thus, they are in-                     Patients selected for this study were
          dicated for situations in which immediate                   screened using the following exclusion
          whitening is required.6 However, in-office                  criteria:
          bleaching requires the use of highly con-
          centrated (usually 35%) hydrogen perox-                     ■   Age less than 18 years old
          ide, which is caustic. Isolation procedures,                ■   Known allergy to ingredients
          such as the use of rubber dam to prevent                    ■   Patient is pregnant or nursing
          hydrogen peroxide contact with soft tis-                    ■   Severe systemic illness
                                          2
          sues, are mandatory. Moreover, 35% hy-                      ■   Restorations in the anterior teeth
          drogen peroxide has been reported to                        ■   Untreated periodontitis or caries
          cause roughening and etching of tooth sur-                  ■   Fixed orthodontic appliances
          faces.7       This   toxicity       potential   and   the   ■   Gingival index score greater than 1.0
          amount of time involved requires the den-
          tist to increase the fee for the treatment.                     All patients received and signed an in-
             Recently, a new generation of whiten-                    formed consent form. This study received
          ing products has been introduced. This                      ethical clearance from the ethical commit-
          new class of products consists of low-                      tee at the Instituto Superior de Ciências da
          concentration hydrogen peroxide or car-                     Saúde Egas Moniz.
          bamide peroxide paint-on varnishes or
          gels to be used by the patients at home.
          Based on the high kinetic release of hydro-
          gen peroxide, manufacturers recommend
          short application times, ranging from 10
          minutes in the most recently marketed ver-
72
THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                              All   C              opyrig
                                                                                 eR
                                                                                                          ht
                                                                      MATA/MARQUES ech
                                                                                      te
                                                                                                             by
                                                                                                      vo
                                                                                                        rbe
                                                                                         Qu
                                                                                                           ha
                                                                                             nt              lte
                                                                                                                n
                                                                                           i
                                                                                                  e ss e n z
Clinical procedure
1. An Optragate retractor (Ivoclar-Viva-
  dent) was placed in the patient’s mouth,
  and the initial shade was recorded with
  the use of a Vita shade guide. Digital
  color photographs were taken with the
  shade guide positioned in the view field
  for documentation purposes (Fig 1).
2. Vaseline gel (Unilever) was applied to
  the gingival margin to prevent contact
  with the peroxide varnish (Fig 2).
3. One thin and uniform layer of the paint-
                                                 Fig 1   Initial shade recording.
  on varnish was applied to the buccal
  surface of maxillary and mandibular
  anterior teeth (canine to canine), as rec-
  ommended by the manufacturer for at-
  home use of this product (see Fig 2).
4. After 10 minutes, the varnish was eas-
  ily removed using an ultrasonic scaling
  device (Fig 3).
5. Steps 2 to 4 were repeated five addi-
  tional times to give a total whitening
  procedure time of 60 minutes.
6. A final photograph was taken with the
  shade guides in place.
  The procedure was repeated after 1
week. A questionnaire was handed to the
patient to assess tooth sensitivity, soft tis-   Fig 2   Application of the Vaseline gel and paint-on
sue irritation, perception of whitening, and     whitening varnish.
overall degree of satisfaction. Gingival tis-
sue was inspected for the presence of
whitening-induced lesions, and these were
classified as absent nonerosive (lesion
without loss of surface integrity) or erosive
(lesion with loss of surface integrity).
                                                 Fig 3   Ultrasonic varnish removal.
                                                                                                               73
                                                           THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
                                                                             VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                                                         All   C    opyrig
                                                                                                            eR
                                                                                                                           ht
               CLINICAL APPLICATION                                                                           ech
                                                                                                                 te
                                                                                                                              by
                                                                                                                       vo
                                                                                                                         rbe
                                                                                                             Qu
                                                                                                                            ha
                                                                                                              nt              lte
                                                                                                                                 n
                                                                                                             i
                                                                                                                   e ss e n z
          Results
          To date, the authors have treated a total of                   Tooth pain or sensitivity was not report-
          six patients using this in-office whitening               ed by any of the patients. All six patients
          technique. The results of these cases are                 noted that they experienced mild discom-
          depicted in Figs 4 and 5. After the second                fort of the gingival tissue. In three of the six
          session, the color change in the maxillary                patients, nonerosive lesions (Fig 6) were
          right canine ranged from 7 to 13 values on                observed, but lasted no more than 20 min-
          the Vita shade guide (Table 1).                           utes following treatment.
           a                                                         b
          Fig 4   Tooth shades for patient 2 before (a) and after (b) two sessions of in-office whitening.
           a                                                         b
          Fig 5   Tooth shades for patient 3 before (a) and after (b) two sessions of in-office whitening.
74
THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                         All   C                  opyrig
                                                                            eR
                                                                                                          ht
                                                                 MATA/MARQUES ech
                                                                                 te
                                                                                                             by
                                                                                                     vo
                                                                                                       rbe
                                                                                         Qu
                                                                                                          ha
                                                                                            nt              lte
                                                                                                               n
                                                                                           i
                                                                                                 e ss e n z
Table 1     Vita shade guide values for the maxillary right canine before and after in-
office whitening treatment
Patient         Vita shade before        Vita shade after          Change in shade value
1                        B4                      A2                               8
2                        A4                      A1                              13
3                       A3.5                     A1                              10
4                       A3.5                     B1                              11
5                       A3.5                     A2                               7
6                       A3.5                     B1                              11
Discussion
The paint-on whitening varnish with a con-
centration of 6% hydrogen peroxide used
in this study is designed for at-home self-
application for 10 minutes twice a day for
14 days. The manufacturer-recommended
short duration application time is based on
the rapid hydrogen peroxide kinetic re-
lease. A previous in vitro study conducted
by the authors confirmed that after 10 min-
utes more than 95% of the hydrogen per-        Fig 6   Nonerosive lesion on gingival tissues following
                                               whitening treatment. All such lesions resolved within 20
oxide was released from the varnish to a
                                               minutes of treatment.
surrounding medium.8 This fact led to the
hypothesis that repeated application of this
product could induce a fast rate of bleach-
ing compatible with in-office use require-
ments. It has been stated that for in-office
bleaching with the use of high-concentra-
tion hydrogen peroxide, two to six appoint-
ments lasting 45 to 60 minutes are usually     duration of the whitening effect is unknown
          9
required. The results obtained show that       at the present time. However, vital bleach-
with two sessions of six 10-minute applica-    ing techniques have proved to be quite
tions, effective whitening can be attained.    predictable, with color stability reported for
Color changes obtained range from 7 to 13      up to several years, and there are no rea-
shade values in the Vita shade guide,          sons found to expect a different result from
which is comparable to the results present-    this technique.9,11 Other whitening products
ed by others with the use of in-office high-   may also be effective, provided they have
concentration hydrogen peroxide.10 The         rapid peroxide kinetic release.
                                                                                                              75
                                                          THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
                                                                           VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                                                  All   C    opyrig
                                                                                                     eR
                                                                                                                    ht
             CLINICAL APPLICATION                                                                      ech
                                                                                                          te
                                                                                                                       by
                                                                                                                vo
                                                                                                                  rbe
                                                                                                   Qu
                                                                                                                     ha
                                                                                                       nt              lte
                                                                                                                          n
                                                                                                     i
                                                                                                            e ss e n z
             Tooth sensitivity, a common side effect         provides a good field of vision, which facil-
          associated with the use of in-office prod-         itates precise product application. More-
          ucts with high peroxide concentrations,            over, in the absence of rubber dam isola-
          was not experienced by any of the patients,        tion, the use of a lip retractor enables
          which is a promising advantage for this            bleaching of both dental arches simultane-
                     12
          technique.      Patient reports of soft tissue     ously.
          discomfort are minimal. Manufacturer rec-             Patients evaluated the overall procedure
          ommendations for at-home use of this               as “good” to “very good” and all patients in
          product do not include protection of the           the study would recommend this proce-
          soft tissue. However, in the first patient we      dure to a friend.
          treated, after several applications we de-
          tected the presence of white nonerosive
          surface lesions on the gingival tissue that        Conclusion
          were asymptomatic and resolved within 20
          minutes following treatment. Similar tissue        In-office bleaching with the use of paint-on
          burns have been reported with the use of           varnishes seems to be effective, safe, and
          highly concentrated hydrogen peroxide              well accepted by patients, offering a viable
                                        13
          during in-office techniques.       To avoid this   alternative to high-peroxide-concentration
          situation, the use of rubber dam to prevent        in-office procedures. Long-term results are
          soft tissue contact with the hydrogen per-         not available at this time. However, a clini-
          oxide is highly recommended.2,9,13 In the          cal study is presently being conducted by
          subsequent cases, the authors applied              the authors to collect more data, which will
          Vaseline gel to the soft tissues, which            help to assess short- and long-term clini-
          served as effective protection of the gingi-       cal effects of this technique.
          va, as shown by the fact that the number
          of lesions observed decreased. Therefore,
          it is reasonable to assume that for this           Acknowledgments
          technique, the use of rubber dam, which is
                                                             The authors would like to thank the Oral Biology
          uncomfortable to the patient and time con-         Research Group colaborators, João Silveira, Joana
          suming to apply, can be avoided, and pro-          Marques, Joana Cabrita, Nuno Guilherme, and João
          tection of the soft tissues can be safely and      Amaral for their contribution to this work; the Clinical
                                                             Director Doctor Maria Armanda Amorim at the Institu-
          easily accomplished with the use of an iso-        to Superior de Ciências da Saúde Egas Moniz for the
          lating medium such as Vaseline. The use            logistic support; and the Administration Board at Egas
                                                             Moniz for funding and support.
          of a lip retractor is also recommended be-
          cause it is easy to apply, comfortable, and
76
THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
VOLUME 1 • NUMBER 1 • APRIL 2006
                                                                                    All   C                 opyrig
                                                                                       eR
                                                                                                                   ht
                                                                            MATA/MARQUES ech
                                                                                            te
                                                                                                                      by
                                                                                                               vo
                                                                                                                 rbe
                                                                                                  Qu
                                                                                                                    ha
                                                                                                      nt              lte
                                                                                                                         n
                                                                                                    i
                                                                                                           e ss e n z
References
1. Joiner A. Tooth colour: A           7. Zalkind M, Arwaz R, Goldman       10. Al Shethri S, Matis BA,
   review of the literature. J Dent       A, Rotstein I. Surface morphol-       Cochran MA, Zekonis R,
   2004;32(suppl):3–12.                   ogy changes in human enam-            Stropes M. A clinical evaluation
2. Goldstein RE. In office bleach-        el, dentin and cementum fol-          of two in-office bleaching prod-
   ing: Where we came from,               lowing bleaching: A scanning          ucts. Oper Dent 2003;28:
   where we are today. J Am Dent          electron microscopy study.            488–495.
   Assoc 1997;125:11S.                    Endod Dent Traumatol              11. Ritter AV, Leonard RH Jr, St
3. Haywood VB, Heymann HO.                1996;12(2):82–88.                     Georges AJ, Caplan DJ, Hay-
   Nightguard vital bleaching.         8. Mata AD, Marques DS, Silveira         wood VB. Safety and stability of
   Quintessence Int                       JM, Marques JF, Huwig A. In           nightguard vital bleaching: 9 to
   1989;20:173–176.                       vitro peroxide release kinetics       12 years post-treatment. J
4. Haywood VB. Current status of          of three paint-on tooth whiten-       Esthet Restor Dent 2002;14:
   nightguard vital bleaching.            ers. Available at: http://iadr.       275–285.
   Compend Contin Educ Dent               confex.com/iadr/eur05/            12. Gallagher A, Maggio B, Bow-
   2000;28:S10–S17.                       techprogram/abstract_67830.           man J, Borden L, Mason S,
5. Greenwall L. Bleaching Tech-           htm. Accessed 29 March 2006.          Felix H. Clinical study to com-
   niques in Restorative Den-          9. Haywood VB, Berry TG. Natural         pare two in-office (chairside)
   tistry—An Illustrated Guide. Lon-      tooth bleaching. In: Schwartz         whitening systems. J Clin Dent
   don: Martin Dunitz, 2001.              RS, Summit JB, Robbins JW             2002;13:219–224.
6. Wattanapayungkul P, Yap AUJ.           (eds). Fundamentals of Opera-     13. Barghi N. Making a clinical
   Effects of in office bleaching         tive Dentistry. Chicago: Quin-        decision for vital tooth bleach-
   products on surface finish tooth       tessence, 2001:401–450.               ing: At home or in office. Com-
   colour restorations. Oper Dent                                               pend Contin Educ Dent
   2003;28:15–19.                                                               1998;19:831–838.
                                                                                                                        77
                                                                   THE EUROPEAN JOURNAL OF ESTHETIC DENTISTRY
                                                                                    VOLUME 1 • NUMBER 1 • APRIL 2006