1.
Normal level of hemoglobin
A.) 100-120 G/L
+ B.) 120-150 G/L
C.) 140-160 G/L
D.) 150-170 G/L
2.Normal red blood cells level
A.) 4-9 x1012
+B.) 3,9-5,0 x 1012
C.) 4-9 x109
D.) 3,9-5,0 x 109
3.Abnormal bleeding can result from disorders of the coagulation system, of platelets, or of blood vessels. Disorders of the coagulation system can
be hereditary or acquired. Of the hereditary disorders of hemostasis, which of the following is the most common?
A.) Hemophilia A
B.) Hemophilia B
C.) Hemorrhagic telangiectasia
+ D.) Von Willebrand disease
4.Patients in whom a coagulation disorder is suspected require laboratory evaluation including prothrombin time (PT) and partial
thromboplastin time (PTT), CBC with platelet count, and peripheral blood smear. When a patient has a prolonged PT with normal platelets and
PTT, which of the following is the most likely diagnosis?
+A.) Factor VII deficiency
B.) Hemophilia A
C.) Liver disease
D.) Vitamin K deficiency
5.A patient with thrombocytopenia has fragmented RBCs on peripheral blood smear and decreasing Hb level. Which of the following is the most
likely suspected diagnosis?
+A.) Hemolytic-uremic syndrome
B.) Hereditary hemorrhagic telangiectasia
C.) HIV infection
D.) Immune thrombocytopenia
6.Tissue plasmin activator _______________
A.) helps in wound healing
B.) allergy response
C.) immunity
+D.) dissolves clot in blood vessels
7.Cardiac output is determined by _______
A.) heart rate
B.) stroke volume
C.) blood flow
+D.) heart rate and stroke volume
8.What do you mean by Hemostasis?
A.) production of new blood cells
+B.) process by which bleeding stops from damaged blood vessels
C.) normal body condition
D.) none of the above
9. Which of the following are the 3 steps of hemostasis?
A.) vascular spasm, platelet adhesion, blood clotting
+B.) vascular spasm, platelet plug formation, blood clotting
C.) vascular spasm, platelet aggregation, blood clotting
D.) vascular spasm, platelet release, blood clotting
10. Why vascular spasm takes place?
A.) due to damage in smooth muscle
B.) due to release of substances by activated platelets
C.) due to the reflex initiated by pain receptors
+D.) all of the above
11. Which of the following options does not come under the substances released by activated platelets?
A.) serotonin
B.) ADP
+C.) urea
D.) Ca ions
12. Which substance along with thromboxane A2 helps activate other platelets during platelet plug formation?
A.) serotonin
+B.) ADP
C.) ATP
D.) lysosomes
13. which of the following is the (iv) clotting factor?
A.) Proaccelerin
B.) tissue factor
C.) stable factor
+D.) none of the above
14. Which of the following statement is NOT true?
A.) hemostasis prevents hemorrhage
+B.) platelet plug is very effective in preventing blood loss from large blood vessels
C.) vitamin K is required for synthesis for several clotting factors
D.) the clot formed is a gel like substance
15. Which of the following is effective in dissolving the clot formed after complete repair of injury?
A.) hageman factor
+B.) plasminolysin
C.) christmas factor
D.) tissue factor
16. Which of the following do not take part in the extrinsic pathways for the formation of prothrombinase?
A.) tissue factor
B.) prowar factor
+C.) stable factor
D.) Ca ions
17. Normal bleeding time
A.) 1-2 mint
+B.) 2-7 mint
C.)10-15 mint
D.) 30-40 mint
18.What is a normal platelet count?
A.) 4-11k
+B.) 150 - 450k
C.) 50-100k
D.) 10-20k
19. What is the normal life span of a red blood cells (RBC)?
A.) 4 weeks
B.) 8 weeks
C.) 70-90 days
+D.) 100-120 days
20. Bleeding disorder also means-
A.) Coagulopathy
B.) Abnormal bleeding
C.) Clotting disorders
+D.) All the above
21. Symptoms of bleeding disorders include
A.) Excessive bleeding or bruising
B.) Nose bleeds
C.) Excessive menstrual bleeding
+D.) All the above
22.The bleeding disorder in which the blood vessels are more fragile than normal, which leads to frequent bleeding episodes is called -
+A.) Hemorrhagic Telangiectasia
B.) Ehlers-Danlos syndrome
C.) Allergic purpura
D.)Thrombocytopenia
23. Which tests can be used to diagnose bleeding disorders?
A.) Bleeding time
B.) Partial thromboplastin time (PTT)
C.) Platelet aggregation test
+D.) All the above
24. Which of the following are complications of hemophilia?
A.) Joint swelling
B.) Bleeding in the head
C.) Death
+D.) All of the above
25.Regarding binding of oxygen with hemoglobin
A.) Oxygen loosely combines with a positive bonds of iron in Hb molecule
B.) Oxygen firmly binds with 1 of the coordination bonds of iron atom
+C.) Oxygen is carried to the tissues in molecular form by Hemoglobin
D.) Oxygen is released by Hb into the tissues in ionic form
26. The 1st step of Heme synthesis takes place in the:
+A.) Mitochondria
B.) Golgi apparatus
C.) Rough endoplasmic reticulum
D.) Peroxisomes
27. Regarding the blood coagulation test "Prothrombin time":
A.) It is normally about 12 minutes
B.) It indicates concentration of thrombin in blood
C.) It involves intrinsic clotting pathway
+D.) It shortens with rise in prothrombin concentration
28. A 24-year-old African American man comes to the emergency room 3 hours after the onset of severe back and chest pain which started when
he was climbing up a mountain. He had an episode of same symptoms five years ago. His values are Hb: ug/dl, TLC: 12,000/mm3, Reticulocyte
count: 25%. What is the diagnosis of this patient?
A.) Acute blood loss
+B.) Sickle cell anemia
C.) Anemia of chronic disease
D.) End stage kidney disease
29. Which of the following treatments would prevent a
transfusion reaction?
A) Administration of plasma free blood
B) Administration of washed erythrocytes
C.) Treatment with immunoglobulins.
+D) Proper cross-matching of donor red cells with recipient plasma
30. What happens following the presentation of an antigen by a macrophage?
A.) Direct generation of antibodies
B.) Activation of cytotoxic T cells
C.) Increase in phagocytosis
+D.) Activation of helper T cells.
31. What causes the release of histamine in an allergic reaction?
A.) Binding of IgM to basophils.
+B.) Binding of IgE to mast cells.
C.) Release of histamine by helper T cells.
D.) Free radical stimulation of endothelial cells
32. Which of the following blood units carries the least risk of inducing an immediate reaction in a type B, Rh+ patient?
A.) Type A +ve whole blood.
B.) Type O +ve whole blood.
C.) Type AB +ve whole blood.
+D.) Type O+ve packed red cells.
33. The protein responsible for iron transport in plasma is
A.) a 1-antitrypsin
B.) Ferritin
+C.) Apo-transferrin
D.) Apo-ferritin
34. Prothrombin level falls in the blood due to lack of
A.) Vitamin B12
+B.) Vitamin K
C.) Phospholipids
D.) Platelets
35. Bluish tint of the polycythemia person is because of excess of
A.) Myoglobin
+B.) Deoxygenated Hb
C.) Oxygenated Hb
D.) Reduced Hb
36. A 6-year-old boy bruises easily and has previously bleeding gums. The maternal grandfather also has a bleeding disorder. You suspect the
deficiency of
A.) Prothrombin activator
B.) Factor II
+C.) Factor VIII
D.) Factor X
37. Regarding Opsonization:
A.) It involves breakdown of antibodies
B.) It means neutralization of antigen by antibody
C.) Antigen gets attached directly to the phagocyte receptor
+D.) Antibody makes a bridge between antigen & receptor
38. A 30 years old male is brought to the hospital with history of gastrectomy. His skin appears lemon-yellow. Investigations reveal hemoglobin 10
g/dl, odd shaped RBCs and Serum Vitamin B is low. He is likely to be suffering from:
A.) Blood Loss Anemia
B.) Pernicious Anemia
+C.) Megaloblastic Anemia
D.) Hemolytic Anemia
39. The mechanism of action of the following substance involves chemotaxis:
+A.) Bacterial & viral toxins
B.) Fungal & parasitic toxins
C.) Regenerative products of inflamed tissues
D.) Plasma clotting enzymes
40.Major Histocompatibility Complex Protein is present on the surface of:
A.) Suppressor T cells
+B.) T Lymphocytes
C.) Cytotoxic T cells
D.) Helper T cells
41. A young boy was brought to hospital emergency with complaint of acute pain in right iliac fossa. On history, examination & clinical
investigation, he was diagnosed to have acute appendicitis. His TLC (per microlit.) is likely to be:
A.) 4,000
B.) 6,000
C.) 10,000
+D.) 14,000
42. By the age of 7 months, the primary site of haematopoiesis in a fetus is:
A.) Thymus
B.) Liver
C.) Spleen
D.) Reticuloendothelial system
+E.) Red marrow
43. The most abundant cells of the blood are:
A.) Platelets
+B.) Erythrocytes
C.) Granulocytes
D.) Leukocytes
44. Paul Bunnel test is positive in:
+A.) Infectious mononucleosis
B.) Multiple myeloma
C.) Malignant nerves
D.) RUbella
45. Hemophilia B is due to:
A.) Factor VII deficiency
+B.) Factor IX deficiency
C.) Platelet deficiency
D.) Vit C deficiency
46. To prevent excessive bleeding during surgery a patient with hemophilia A may be given:
A.) Whole blood
B.) Fresh frozen plasma
+C.) Factor VIII concentrate
D.) Factor IX concentrate
47. Which of the following disease is known as the " kissing disease" ?
A.) Acquired immunodeficiency syndrome
+B.) Infectious mononucleosis
C.) Primary syphilis
D.) Recurrent aphthous stomatitis
48.Which of the following is seen in idiopathic
thrombocytopenic purpura?
A.) Thrombocytosis
B.) Increased prothrombin time
+C.) Increased bleeding time
D.) Increased clotting time
49. Neurological symptoms and premature graying of hair is associated with:
A.) Folic acid deficiency
+B.) Pernicious anemia
C.) Plummer-Vinson syndrome
D.) Paterson-Kelly Syndrome
50. Which of the following is not a finding in classical hemophilia (hemophilia A) ?
A.) Bleeding into soft tissues, muscles and joints
B.) Decreased factor VIII
+C.) Increased prothrombin time
D.) Increased partial thromboplastin time
51. The red blood cells in beta thalassemia are typically:
A.) macrocytic and normochromic
+B.) microcytic and hypochromic
C.) normocytic and hypochromic
D.) normocytic and normochromic
52. Life span of platelets in
+A.) 8-10 days
B.) 2-3 days
C.) 100-120 days
D.) 70-90 days
53. Normal range in PT.
A.) 2-7 mint
+B.) 10-20 second
C.) 10-20 mint
D.) 0-10 mint
54. Which of the plasma proteins.
A.) Albumin,
B.) Globulins
C.) Fibrinogen
+D.) All of the above
55. Blood is a which type of tissue?
A) Epithelial tissue
+B) Connective tissue
C) Both a and b
D) None of the above
56. Which one is responsible for the red color of human blood?
A) Plasma
+B) Hemoglobin
C) WBC
D) Haemocyanin
57. Which of the given blood groups is a universal donor?
A) A
B) AB
C) B
+D) O
58. Which of the given blood groups is a universal recipient?
+A) AB
B)O
C)A
D)B
59. Which of the given acts as a defence against infection?
+A) WBC
B) RBC
V) Blood plasma
D) Hemoglobin
60. What is the Ph value of blood?
A) 6.4
+B) 7.4
C) 8.5
D) 4.9
