General Biology 1                                                                                 QUARTER 1
BY: 11 STEM 1 | 09.30.23 | T
                          OUTLINE                                      3. All cells came from pre-existing cells
  I. Main Characteristics of an Organism                                     • Omnis cellula e cellula
  II. The Cell Theory                                         Expanded version of the cell theory
       A. People Beyond The Cell Theory                              4. Cells carry genetic material passed to
       B. Portions of The Cell Theory
                                                                         daughter cells during cellular division
       C. Endosymbiotic Theory
  III. Cell Structure and Functions                                  5. All cells are essentially the same in chemical
       A. Plasma Membrane                                                composition
       B. Nucleus                                                    6. Energy flows (metabolism and biochemistry
       C. Cytoplasm
                                                                         occurs within cells)
  IV. Prokaryotic vs. Eukaryotic Cells
  V. Cell Types                                                             C. ENDOSYMBIOTIC THEORY
  VI. Cell Modifications                                              D. LYNN MARGULIS – AMERICAN BIOLOGIST
                                                                  •    Provided evidence that some organelles within
 I.   MAIN CHARACTERISTICS OF AN                                       the cells were at one time free living cells
      ORGANISM                                                         themselves
      •   Made of Cells                                           •    Organelles with their own DNA
      •   Requires energy                                         •    Chroloplasts and Mitochondria
      •   Able to reproduce
      •   Maintain homostasis                                 III. CELL STRUCTURE AND FUNCTIONS
      •   Organized
                                                                                A. PLASMA MEMBRANE
      •   Respond to environment
      •   Grow and develop                                    Plasma Membrane/Cell Membrane
      •   Exchange materials with the surroundings                •    Composed of proteins and phospholipid bilayer
      •   Needs of water                                          •    Surrounds outside of all cells
      •   Definite lifespan                                       •    Controls what enters or leaves the cells
      •   Has genes and heredity                                 • It is a living layer
                                                              Phospholipids Bilayer
 II. THE CELL THEORY                                              •    Heads
                                                                       → Contains glycerol and phosphate
           A. PEOPLE BEYOND THE CELL THEORY
                                                                       → hydrophilic
 Robert Hooke                                                     •   Tails
      •   Published the “micrographia” on 1665                        → are made of fatty acids
      •  Observed a box-shaped structure which he called              → hydrophobic
         “cells” as they reminded of him of the cells or      Cell Membrane Proteins
         room in monestries                                       •    helps more large molecules
 Antonie van Leeuwenhoek                                          •    aids in cell recognition
    • On 1670s, he discovered bacteria and protozoa               •    Peripheral proteins
 Matthias Shleiden – German Botanist                                   → Attached on the surface
    • He concluded that all plants are made of cells              •    Integral proteins
 Theodore Schwann – German Zoologist                                   → Embedded          completely      through   the
    • He concluded that all animals are made of cells                      membrane
 Rudolph Virchow                                                  •    Glycoproteins
      •   Observed under a microscope the cells are                    → have carbohydrate tails to act as markers for
          dividing                                                         cell recognition
      •   He reasoned that all cells came form pre-existing   Cell Wall
          cells by cell division                                  •    non living organsim
             B. PORTIONS OF THE CELL THEORY                       •    made of cellulose in plants
 Modern Cell Theory                                               •    made of peptidogylcan in bacteria
        1. All life is composed of one or more cells              •    made of chitin in fungi
        2. Cell is a basic unit of life                           •    supports and protects cell
KNCHS 11-STEM 1 | Pray, Play, Study, and Serve                                                                       1|5
    •    found outside the plasma membrane                         •   Cristae (singular = crista) – folded inner
                          B. NUCLEUS                                   membrane
                                                                       → Increase surface area for more chemical
The Central Organelle – Nucleus
                                                                            reactions
    •    Controls the normal activities of the cell
                                                                   •  Mitochondria came from cytoplasm in the egg cell
    •    Contains the DNA and chromosome
                                                                      during fertilization
    •    Bounded by a nuclear envelop (membrane) with
                                                                      → You inherit your mitochondria from your
         pores
                                                                          mother
    •    Largest organelle                                     Endoplasmic Reticulum
    •   Each cells has fixed number of chromsome that              •   Hollow membrane tubules
        carry genes
                                                                   •   Connects to nuclear membrane and plasma
        → Genes controls cell characteristics
                                                                       membrane
Nuclear envelope
                                                                   •   Functions in synthesis of cell products and
    •    Double membrane surrounding the nucleus
                                                                       transport
    •    also called nuclear membrane
                                                                   •   Rough E.R.
     • connected to the rough endoplamsic reticulum                    → has ribosomes on its surface
Inside the Nucleus                                                     → makes membrane protein and protein for
    •    where the genetic materials is found                             exports out of cell
    •    DNA is spread out and appears as chromatin in                 → protein are made by ribosomes on rough E.R.
         non-dividing cells                                            → threaded to the interior of rough E.R.
    •  DNA is condensed and wrapped around proteins                •  smooth E.R.
       forming as chromosomes in dividing cells                       → lacks of ribosomes on its surface
What does DNA do?                                                     → attached to the end of rough E.R.
    •    It is the hereditary material of the cell                    → makes cell products that are used inside the
    •   Genes that make up the DNA molecule code for                     cell
        differend proteins                                            → makes membrane lipids (steroid)
Nucleolus                                                             → regulates calcium (muscle cells)
    •    Located inside the nucleus                                   → destroy toxic substances (liver)
    •    Cell may have one to three nucleoli                   Ribosomes
    •    Disappears when cell divides                              •   made of proteins and rRNA
    •    Makes ribosomes that makes protein                        •   protein functions for cell
                        C. CYTOPLASM                               •   joins amino acids to make protein
                                                                   • process called protein synthesis
         →    Cytoskeleton
                                                               Golgi Body
    •    Helps maintain the cell shappe
                                                                   •   stacks of flattened sacs
    •    Helps organelles move around
                                                                   •   have trans face and cis face
    •    Made up of proteins
                                                                   •   transport vesicles with modifies protein pinch off
    •    Microfilaments are thread-like
                                                                       the ends
         → made up of Acitin
                                                                   • modifies, sorts, packages
    •    microtubules are tube-like
                                                               Lysosome
         → made up of Tubulin
                                                                   •   contains digestive enzymes
Centrioles
                                                                   •   break down food, bacteria, and warm out cell
    •    only found in animal cells
                                                                       parts
    •    paired structure around nucleus
                                                                   •   programmed for all cell death (autolysis)
    •    made of blundles of microtubules
                                                                   •  Lyse (break open) and release enzymes to break
    •    appear during cell division farming mitotic spindle
                                                                      down and recycle cell parts
    •  help to pull chromosome pairs apart to opposite
                                                               Lysosome Digestion
       ends of the cell
                                                                   •    Cells take in food by phagocytosis
Mitochondria
                                                                        → Lysosome digest the food and get rid of the
    •    singular = mitochondrion
                                                                             waste
    •    generate cellular energy (ATP)
                                                               Cilia and Flagella
         → Adenosine Triphosphate)
                                                                   •   Made of microtubules
    •    Site for cellular respiration (buring glucose)
                                                                   •   9+2 arrangement – (microtubules)
Y2 B9 M1 L2 | Lecture Title                                                                                         2|5
    •    Function in moving cells, in moving fluids, or in                    B. EUKARYOTIC CELLS
         small particles across the cell surface
                                                             Eukaryotes
    •    Cilia
                                                                •   Cells that have a nucleus and membrane-bound
         →       shorter
                                                                    organelles
         →       numerous on cells
                                                                •   Includes protists, fungi, plants, and animals
    •   Flagella
                                                                •   Makes complex cell types of cells
        → Longer
                                                                •   Contains three basic structure:
        → Fewer (usually 1-3) on cells
                                                                    → Plasma membrane or cell membrane
Vacuoles
                                                                    → Nucleus
    •    Fluid filled sacs of storage
                                                                    → Cytoplasm
    •    Small or absent in animal cells
                                                                •   Two main types of eukaryotic cells:
    •    No vacuoles in bacterial cells
                                                                    → Animal cell
    •    In plant, they store cell sap
                                                                    → Plant cell
    •   Includes storage of sugars, proteins, minerals,             →
        lipids, wastes, salts, water, and enzymes
Contractile Vacuole                                          V. CELL TYPES
                                                             Tissue – group of cells having a similar structure and
    •    Found in unicellular protist like paramecia
                                                             functions
    •    Regulate water intake by pumping out excess
                                                                •   Plant tissue
         (homostasis)
                                                                    → do not move/static
    • Keeps the cell from lysing (bursting)
                                                                    → growth of plants takes place on a particular
Chloroplast
                                                                        region
    •    Found only in producers (organisms containing
                                                                •   types of plant tissue
         chlorophyll)
                                                                    → meristematic tissue – group cells that have
    •    Use energy from sunlight to make our food
                                                                        the ability to divide
         (glucose)
                                                                    → permanent tissue – consisting of cells that
    •    Stored in chemical bonds of sugar
                                                                        are no longer actively dividing
    •    Double membrane
                                                                •   Animal tissue
    •    Inner membrane modified into sacs called
                                                                    → It moves
         thylakoids
                                                                    → Needs more energy
         → Thylakoids in stacks called Grana and
              interconnected                                 VI. CELL MODIFICATION
    •    Stroma – gel like material surronding thylakoids                   A. MERISTEMATIC TISSUE
    •    Contains its own DNA                                Meristem
    •    Cointains pigment fro photosynthesis                   •   Type of tissue found in plants
    •    Photosynthesis – food making process                   •   Consists of undifferentiated cells capable of cell
                                                                    division
IV. PROKARYOTIC VS. EUKARYOTIC                                  •    Meristem classification
                                                                     → Apical modification
    CELLS                                                            → Lateral modification
                     A. PROKARYOTIC CELLS                            → Intercalary modification
Prokaryotes                                                  Apical modification
    •    The first cells                                        •   Cell modification found on the apical surface of
    •    Cells that lack nucleus and membrane-bound                 the cell
         organelles                                             •   Cilia and Flagella
    •    Simplest type of cells                                     → Cilia are usually short, hair-like structures that
    •    Single, cellular chromosome                                     moves in waves
    •    Includes bacteria                                          → Flagella are long whiplike structures
                                                                    → Formed from microtubules
    •    Nucleoid regions (center) contains the DNA
    •    Surrounded by a cell membrane and cell wall            •   Villi and Microvilli
                                                                    → Villi are finger-like projections that arise from
         (peptidoglycon)
                                                                          epithelial layers in some organ. They help to
    •    Contains ribosomes (no membrane) in their
         cytoplasm to make proteins
Y2 B9 M1 L2 | Lecture Title                                                                                         3|5
              increase surface area allowing faster and                  →   The cells have an oval or round shape
              more efficient absorption                                  →   The cell wall is made up of hemicellulose or
         →    Microvilli are small projections that arise from               cellulose
              the cell’s surface allowing to increase surface            →   The cell is thin-walled
              area for faster and more efficient absorption              →   The cells have vacuoles and very small
    •    Pseudopods                                                          nucleus
         → Temporary, irregular lobes formed by                          →   It is found in all parts of the plant
            amoebas and some eukaryotic cells                            →   The protoplasm is living and dense
         → Bulge outward to move the cell or engulf prey             •   Colenchyma
    •    Extra Cellular Matrix (ECM)                                     → Cells are long and thick-walled
         → Compound secreted by the cell on its apical                   → The cell wall is made up of cellulose and
             surface                                                         pectin
         → Cell wall is the extra cellular structure in plant            → It is the only tissue with the highest refractive
             cells that distinguish them from animal cells                   index due to the presence of pectin
         → Glycoprotein is the main component of ECM                     → It is found in the epidermis and the vascular
             in animal cell                                                  bundle of dicot leaf
Lateral Modification                                                     → The amount of chloroplast is less in the cells.
    •    A type of cell modification found on the basal                  → The cells have no intercellular spaces
         surface of the cell                                         •  Schlerenchyma
    •    Helps increase the girth                                       → These are dead tissues, very hard and rigid in
    •    Gap junction                                                       texture
         → Also known as communicating junctions                        → Cells are thick-walled with various size and
         → Closable    channels that connect the                            shapes
            cytoplasm of adjoining animal cells                         → These provide mechanical support and
    •  Tight junction                                                       rigidity to the plant
       → It anchors junction on the lateral surface of           Complex Permanent Tissue
            the cell                                                 •   Xylem
       → It is similar to the anchoring junction of the                  → It transports water and nutrients from the
            basal surface of the cell                                        roots to the leaves of the plant
Basal modification                                                       → It provides support to the plants
    •    Type of cell modification found in the basal                    → It is divided into-tracheids, vessels, xylem
         surface of the cell                                                 fiber, and xylem parenchyma
    •    Desmosomes/Hemidismosomes                                   •   Pholeom
         → The anchoring junction of the basal surface of                → It translocates the prepared organic food
            the cell                                                         from the leaves to different parts of the plant.
         → Rivet-like links between cytoskeleton and                     → It is also known as bast
            ECM components such as basal lamina that                     → It is composed of sieve tubes, companion
            underlie epithelia                                               cells, phloem parenchyma, and phloem fibers
         → Primarily composed of keratins, integrins, and
            cadherins
                                                                 REVIEW
                    B. PERMANENT TISSUE
                                                                 1. Question
    •    Tissues that are completely grown and lost the              A. Choice
         ability to divide                                          B. Choice
    •    From meristematic tissue                                   C. Choice
    •    Simple Permanent Tissue                                    D. Choice
         → Also known as homogenous tissue                       2. Question
         → They are made up of a single cell type, usually           A. Choice
            with the same origin, structure, and function           B. Choice
    •   Complex Permanent Tissue                                    C. Chioice
        → Made up of various types of cell carrying out             D. Choice
           distinct functions
Simple Permanent Tissue                                                                                          Answer key
    •    Parenchyma
Y2 B9 M1 L2 | Lecture Title                                                                                             4|5
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REFERENCES
1. Squarepants, S.B., 2019. Title of Lecture
2. Squarepants, S.B., 2019. Title of Lecture
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