EMILIO AGUINALDO COLLEGE

School of Nursing

DRUG STUDY

Medication Classification and Indication Mechanism of Action Contraindications Adverse Effects Nursing Considerations
Category

Generic Name: Pregnancy Category: Hyoscine butylbromide Its anticholinergic contraindicated in - tachycardia
Hyoscine n Category B2 (scopolamine action exerts a myasthenia gravis, - hypotension - Drug compatibility
Butylbromide butylbromide) smooth-muscle mechanical stenosis in the - anaphylaxis should be
There is limited data [Buscopan/Buscapina] relaxing/spasmolytic gastrointestinal tract, monitored closely
Brand Name: from the use of is an antispasmodic effect. Blockade of the paralytical or obstructive in patients
Buscopan hyoscine drug indicated for the muscarinic receptors ileus, megacolon and in
in the GI tract is the requiring
butylbromide in treatment of abdominal patients who have
basis for its use in the adjunctive therapy
Dosage: 20 mg pregnant women. As pain associated with demonstrated prior
treatment of - Avoid driving &
a precautionary cramps induced by hypersensitivity to Side Effects
measure, it is abdominal pain operating
Route: IV/IM/SUBQ gastrointestinal (GI) hyoscine butylbromide or
preferable to avoid secondary to machinery after
spasms. cramping. Hyoscine any other component of - abdominal parenteral
the use of
Frequency: 4 times daily butylbromide also the products. fullness administration.
BUSCOPAN® during
binds to nicotinic - constipation
pregnancy. There is - Avoid strict heat
- urinary retention
insufficient receptors, which - Raise side rails as a
- blurred vision
Pharmacokinetics information on the induces a precaution
- skin flushing
excretion of ganglion-blocking because some
- tachycardia
Onset: 30-60 mins BUSCOPAN® and its effect. - decreased patients become
Peak: 2 hrs metabolites in sweating temporarily
human milk. - salivation excited or
Duration: 30mins
disoriented and
Half-life: 5hrs
some develop
amnesia or
EMILIO AGUINALDO COLLEGE
School of Nursing

become drowsy.
- Reorient patient,
as needed,
Tolerance may
develop when
therapy is
prolonged
- Atropine-like
toxicity may cause
dose related
adverse reactions.
Individual
tolerance varies
greatly
- Overdose may
cause curare-like
effects, such as
respiratory
paralysis. Keep
emergency
equipment
available.