Organic Compost Challenges for Medicinal Plants
Organic Compost Challenges for Medicinal Plants
ABSTRACT: Although the demand for organic fertilizers in agriculture is growing, it remains
incipient in some production sectors, such as medicinal plant production, which does not possess specific
technology for its development. Solid residues are highly contaminant to water sources, soil, populations and
biodiversity but can potentially be used to produce organic composts and vermicompost, such production not
only enables nutrient recycling but also acts on soil conditioning, increasing soil organic matter and improving
its physical, chemical and biological characteristics, as well as strengthening organic production with an
emphasis on medicinal plant production. In this context, recommendations for and applications of organic
fertilizers available in the market were reviewed; in addition, the imminent socioeconomic demand for organic
compost and vermicompost production was contextualized based on residues from coffee and sugarcane
production and cattle farming for application to the medicinal plant production chain. It is concluded that
although these sectors produce a considerable amount of residues, they are not being reused in formulation of
organic composts and vermicompost, and commercial organic fertilizers recommended for medicinal plant
production were not found. Thus, the formulation of vermicomposting and composting from the reuse of
agricultural residues, are potential social, economic technologies and tools to be valued and disseminated to
traditional and family farmers.
incipient. Therefore, the aim of this review was to the standard food production model in Brazil
contextualize the importance of reusing agricultural (SAMPAIO; NETO, 2018).
and animal farming residues to produce organic In parallel with the green revolution, the
composts and vermicompost aimed at the industrial revolution promoted the industrialization
production of medicinal plants and active of the countryside, which had strong environmental
compounds of pharmacological and biological impacts caused by the intensive use of fossil fuels
interest. (PEREIRA; SOUSA, 2016; SAMPAIO; NETO,
2018). In this context, the pharmaceutical industries
DEVELOPMENT developed side by side, comprising the hegemonic
production model of “disease and cure” and
The bibliographic research was carried out contributing to the irrational use of agrotoxics and
by compiling publications on agricultural bases drugs as a way of maintaining profit and hegemony
indexed on free access digital platforms that work (MONTEIRO; LACERDA, 2016; MENDONÇA et
with the commercialization of organic fertilizers. al., 2015; BARROS, 2018).
The companies evaluated in this research were (1) Therefore, although populations have
Terra Fértil; (2) Plantei; (3) NutriSafra; (4) historically used medicinal plants, after the
MfRural; (5) Neudfor; (6) Agrobio; (7) Folhito Mix; industrial revolution, natural products were replaced
(8) Fish fértil; (9) Microbio. The total of 33 organic by synthetic drugs on a massive scale. The New
fertilizers made available by these companies were Chemical Entities of pharmaceutical products
listed and the analysis and systematization of the recorded that at least 27% of synthetic drugs
commercial name, composition and agricultural originate from plant biodiversity and are formulated
recommendation of organic fertilizers for the crops from natural products via chemical synthesis
of interest were made. (ALVES; PONTES, 2017). Therefore, there is a
deficit in the development of services, technologies
Factors determining the stagnation of medicinal and research related to medicinal plant production in
plant production Brazil (TORRES, 2015).
The establishment of agricultural production The stagnation observed in medicinal plant
chains is not an isolated factor within the economic production is caused by the fact that food, natural
development of countries; there are socioeconomic products and drug production are not foreign to
and historical processes intrinsic to the production societal factors but instead depend on political and
of food, goods and services (SOUSA; GOIÁIS, economic interests (RONDÓ; LOPES, 2016). In this
2015). In this context, changes in agriculture began scenario, medicinal plant production was not
with the Green Revolution and culminated in the historically recognized as an agricultural production
economic globalization that began in the 1990s; this chain or as having political and economic interest; it
globalization was organized around large only reemerged as potent and innovative in the
companies, agricultural industries and 2000s (PIMENTEL, 2015). Accordingly, there is an
multinationals that control the world market imminent demand for technologies and research in
LAZZARI; SOUZA, 2017; MATOS; PESSOA, medicinal plant production (HEINZMANN;
2011). Ever since the colonial period, an essentially BARROS, 2007; RIBEIRO et al., 2014; ASSIS;
organic based-agriculture has been replaced by MORELLI-AMARAL; PIMENTA, 2015).
techniques that depend on chemical inputs, whereas
the Brazilian agricultural policy prioritizes The brazilian scenario of medicinal plant and
incentives to commodity export (FLORES; herbal drug production: expanding demand
GREGORI; ARAÚJO, 2013; PEREIRA; SOUSA, The use of medicinal plants in popular
2016; GURGEL; GIRALDO, 2017) with medicine in Brazil, especially by traditional peoples
agribusiness justifying production chains that have (Quilombolas, Native Peoples, Riparian
the goal of gathering agrochemical, industrial and Communities), is historically expressive and has
commercial activities and land monopolies and been exploited by Brazilian researchers and the
directing them toward the external market (SAUER; pharmaceutical industry (CALIXTO; SIQUEIRA,
LEITE, 2012; MENDONÇA, 2015). 2008; LIRA; CHAVES, 2015). The interest in plant-
To establish agriculture and animal farming, derived drugs, especially from medicinal species, is
it has been necessary to standardize cultivation and growing worldwide given that 30% of the available
to industrialize and optimize production chains, therapeutic drugs are either directly or indirectly
which are essential factors in the expansion of derived from natural products (KOEHN; CARTER,
agribusiness at an international level, consolidating
2005; LIMA; GOMES, 2014; MENDONÇA et al., political factors, despite its biodiversity, Brazil still
2018). depends on raw material produced by multinationals
Brazil is the country with highest from developed countries such as USA, China,
biodiversity in the world, with an estimated over Israel, Korea and India (CALIXTO, 2000; KOEHN;
50,000 species of higher plants (20-22% of the total CARTER, 2005). Given this scenario, for the last 15
worldwide), along with mammals, birds, insects and years, the Ministry of Health has invested in public
microorganisms (RODRIGUES, 2016). The use of policies to promote and consolidate medicinal plant
medicinal plants by the population through living production and strengthen the national
pharmacies and phytotherapy (TORRES, 2015) are pharmaceutical industry. Some of these national
essential to meet this demand (ARAÚJO et al., policies were the National Policy of Integrative and
2013) Brazilian revenue from this sector is Complementary Practices - National Policy of
approximately US$ 160 million per year, Integrative and Complementary Practices – PNPIC
constituting a promising market whose raw (PERFEITO; ANDREOTTI, 2019), the National
materials are medicinal plants (RODRIGUES, Policy of Medicinal Plants and Herbal Drugs
2016). (National Policy on Medicinal Plants and Herbal
The high profitability of herbal drug Medicines, 2006) and the National Program of
production contradicts the myth by the synthetic Medicinal Plants and Herbal Drugs (National
pharmaceutical industry that this market is of little Program for Medicinal Plants and Herbal Medicines
economic importance (CARVALHO et al., 2011). In – PNPMF).
addition, the implementation of RDC 26/2014, The public policies mentioned above
regulating “Traditional Phytotherapy Products”, established important decrees for productive
contributed to the sector’s development, demanding advancement, such as RDC nº 60 (2011), approving
advances to establish the production chain. the Herbal Drugs Form of the Brazilian
Medicinal plants (native and exotic) and Pharmacopoeia, which contains 83 herbal drug
their derivates are used by the Brazilian population monographies, and RDC nº 13 (2013) of Good
and are among the main therapeutic resources for Practices for Traditional Herbal Drug Production
the traditional and complementary/alternative and the National Drug List (2014).
medicine (TM/CAM) used in primary health care, The National Sanitary Surveillance Agency
according to a diagnostic by the Ministry of Health (ANVISA) regulates the analysis of agrochemical
(MACEDO, 2016). This enables the appearance of residues in the Brazilian Pharmacopoeia, but
new opportunities for the creation of production residues of undesirable and undeclared substances
cooperatives both in traditional communities and in such as pesticides, radioactive materials, pathogens,
companies. mycotoxins, heavy metals and arsenic remain
According to Marques et al., 2007, present in plant and herbal drugs (BRASIL, 2011).
establishing policies for medicinal plants and herbal The PNPMF guidelines establish actions with the
drugs depends on multiple investments in their aim of promoting technological, economic and
production chain, namely, by universities and social development that require articulation between
companies (MACEDO, 2016) from the plant to the institutions to stimulate and consolidate the
final product. In this sense, technologies need to be production complex.
developed that support medicinal plant production The Local Productive Arrangement, which
from farms to processing units and/or industry. is aimed at strengthening the implementation of this
Therefore, there is a socioeconomic demand for public policy and includes stages from input
investment in medicinal plant production chains production (cultivation/management) to
from cultivation to processing to advance the industrialized herbal drug production, shows the
national pharmaceutical industry, which depends on innovation, economic, technological and social
the supply of raw material at an industrial scale to potential of industrialized herbal drugs (TORRES,
develop herbal and natural drugs with safety, 2015), and considers family farming one of the main
efficacy and quality certification; such drugs components of this production chain.
demand fewer resources and have lower risks than In this context, establishing a medicinal
synthetic drug production (CALIXTO et al., 2000; plant production chain remains an imminent
LOPES; NASCIMENTO, 2017; LIMA, 2015; demand, requiring basic studies from production of
MATOS, 2016). inputs to be used in plantations to evaluations of the
Drug production is therefore an essential active components present in the planted species,
factor of national sovereignty and safety (PADULA, with the aim of meeting the safety and efficacy
2017). However, because of socioeconomic and
criteria for medicinal plant and herbal drug centralized in multinationals) need to be
production. reevaluated.
Table 1. List of commercial organic composts and vermicompost available in the Brazilian market.
The agricultural and animal farming residue However, residue recycling is essential to
composition of the 33 products listed above is reduce the consumption of natural resources in
diverse. However, the use of coffee straw and agriculture, since new products (organic composts
vinasse is not directly mentioned, and most are and/or vermicompost) are produced from the
enriched with some elicitor molecule (fulvic acid, residues of industrial and agricultural activities,
humic acid, free amino acids and algae) in addition which can be applied to the production of different
to microorganisms that efficiently contribute to crops. In addition to allowing for nutrient recycling,
promoting plant growth (CALVO; NELSON; these organic composts and vermicompost act as
KLOEPPER, 2014). soil conditioner, increasing the levels of organic
These commercial products are mainly matter and resulting in improved physical, chemical
destined for cereals, fruits and vegetables, annual and biological soil characteristics (WU et al., 2014;
crops and flower production. No recommendations MORAES, 2015; LIM; LEE; WU, 2016; SOARES
for application to medicinal plants were found. et al., 2017).
Although many medicinal plants present similar However, composting is the most often used
development to some of the listed species, the focus and accepted method of organic residue recycling in
is raw material and not the effect of the commercial agriculture because it stabilizes the material,
product on the elicitation of active components with avoiding nutrient immobilization and phytotoxicity
pharmacological and biological properties. (GUIDONI et al., 2013). Organic compost has
several benefits for agricultural production and for organic food production is undergoing constant
the soil, since in addition to supplying nutrients to growth, along with medicinal plant production, with
plants, it promotes the complexation of toxic a high demand for technologies, services and
elements and micronutrients, improves soil products. This sector will only be able to advance
structure, and results in higher microbial activity, through the efforts of research institutions and
soil carbon accumulation, and water infiltration and continuing education, strengthening family farming
retention, acting as a soil conditioner (SANTOS et and the permanence of families in the countryside.
al., 2014). The production of specific organic composts and
The reuse of solid residues to produce vermicompost for the production of medicinal plants
organic composts and/or vermicompost is therefore (raw material) rich in active compounds with
a technology with potential for plant growth biological and pharmacological activity is therefore
promotion, since the byproducts of agroindustry crucial to strengthening the national pharmaceutical
(agriculture and animal farming) constitute a health industry for both the production of herbal drugs and
problem (DIAS et al., 2012), contaminating soil, the consolidation of public policies related to
water, air and people when they are not disposed of medicinal plants and herbal drugs through the
in a manner that is coherent and responsible toward prescription of dry plants by the SUS. It is
the environment. In addition, conventional highlighted that developing technologies and studies
fertilizers that depend on natural resources (mineral for the reuse of residues from sugarcane, beef and
fertilizers) are becoming exhausted by the dairy cattle and coffee production for the production
irresponsible exploitation of large agribusiness of commercial products and/or social technology,
companies and multinationals. which can then be reapplied to the production
The need for advances in the production of sector, will fulfill the social duty of knowledge of
technologies applied to medicinal plant the population and environment, generating jobs,
development and growth that not only promote raw products, sovereignty and food safety through the
material production but also elicit the secondary production of organic food and medicinal plants.
metabolism, resulting in higher essential oil yield
and active ingredient concentrations, should be ACKNOWLEDGMENT
highlighted.
This study was financed in part by the
FINAL CONSIDERATIONS Coordenação de Aperfeiçoamento de Pessoal de
Nível Superior – Brasil (CAPES) – Finance Code
Agricultural production chains are of great 001, Conselho Nacional de Desenvolvimento
importance to the economic movement of small and Científico e Tecnológico (CNPq) and Fundação de
large producers. However, methods of reusing Amparo à Pesquisa de Minas Gerais
agricultural and animal farming residues need to be (FAPEMIG) for the financial support for
established to avoid contamination of water sources, carrying out the work.
soil, fauna, flora and population. In addition,
countering the agrobusiness production model,
RESUMO: Embora a demanda por fertilizantes orgânicos na agricultura seja crescente, ela ainda é
incipiente em alguns setores produtivos, como a produção de plantas medicinais, que não possui tecnologia
específica para seu desenvolvimento. Os resíduos sólidos são altamente contaminantes para fontes de água,
solo, populações e biodiversidade, mas podem ser potencialmente utilizados para a produção de compostos
orgânicos e vermicomposto, tal produção não só possibilita a reciclagem de nutrientes, mas também atua no
condicionamento do solo, aumentando a matéria orgânica do solo e melhorando seu aspecto físico, químico e
características biológicas, além do fortalecimento da produção orgânica com ênfase na produção de plantas
medicinais. Nesse contexto, foram revisadas as recomendações e aplicações dos fertilizantes orgânicos
disponíveis no mercado; além disso, a iminente demanda socioeconômica pela produção de composto orgânico
e vermicomposto foi contextualizada a partir dos resíduos da produção de café, cana-de-açúcar e pecuária para
aplicação na cadeia produtiva de plantas medicinais. Conclui-se que embora esses setores produzam uma
quantidade considerável de resíduos, eles não estão sendo reaproveitados na formulação de compostos
orgânicos e vermicomposto, e não foram encontrados fertilizantes orgânicos comerciais recomendados para a
produção de plantas medicinais. Sendo assim, a formulação de vermicompostagem e compostagem a partir do
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