Premium Time Reverse Cream-Introduction-07.2021
Premium Time Reverse Cream-Introduction-07.2021
2021)
(NEW)
PREMIUM TIME REVERSE CREAM (Face&Neck), 30 ml
(airless jar)
A supercharged moisturizing cream for your skin's youthful radiance.
BENEFITS
• Improves the appearance of crepey skin, fine lines, and wrinkles.
• Minimizes the appearance of redness and discoloration.
• Helps increase skin hydration.
• Works with the skin to clear out damaged elastin and collagen.
• Supports the production of new, healthy elastin and collagen.
• Works synergistically with tightening, toning, and pigmentation removal procedures.
INGREDIENTS:
Purified water, Isononyl Isononanoate, Cetearyl Olivate - Sorbitan Olivate, Niacinamide, SERASILK (Dimethicone/Vinyldimethicone and C12-
14 Pareth-12), 1.3-Butylene Glycol, Hyluronic Acid (LMWHA), Salicylic Acid, Myristyl Myristate, Propylene Glycol, SKINECTURA (Glycerin
(and) Aqua (and) Anigozanthos Flavidus Extract), TENS'UP (Aqua (and) Glycerin (and) Caesalpinia Spinosa Gum (and) Cichorium Intybus
Root Oligosaccharides), Dimethicone, Acetyl Hexapeptide-8, VISCOLAM (Sodium Polyacryloyldimethyl Taurate (and) Hydrogenated
Polydecene (and) Trideceth-10), Tocopheryl Acetate, UNICLAY (Glycerin (and) Aqua (and) Bacillus Ferment), Phenoxyethanol, Xanthan
Gum, Chlorphenesin.
1
CLINICCARE PREMIUM TIME REVERSE CREAM (Face&Neck), 30 ml (07.2021)
botanical extract standardized in fructose & rutin content. It increases the secretion of structural
proteins, collagen and elastin. It rapidly decreases the appearance of wrinkles after 1 hr with
continuous improvement over 28 days. It is a natural multi-target and innovative ingredient that offers
a rapid and long-lasting unique approach to the passage of time providing healthier, younger, and
more beautiful looking skin.
• TENS’UP: is an innovative active ingredient with a marked lifting and tightening effect. Immediately
causes lifting effect to the skin and visibly smooths wrinkles. Tens’Up and Retinol show comparable
activity. Increases collagen synthesis with wrinkle-replenishing effect. The immediate lifting or
tightening action of the skin surface is a cosmetic property that exerts macromolecules such as
collagen, chitosan, keratin, hyaluronic acid, biopolymers and others. The mechanism of action of these
molecules is to exert sufficient mechanical tension on the skin to smooth the cutaneous surface and
provide a smooth and resplendent appearance instantly. These macromolecules form a surface film
that smoothes the skin, erases wrinkles and expression lines, and provides a more radiant and
luminous appearance. The prolongation of this tightening effect depends exclusively on the film itself.
Its dual action makes it possible to obtain "flash" products with anti-ageing properties.
• ACETYL HEXAPEPTIDE-8: also known as “botox in a jar.” This peptide delivers impressive results when
targeting fine lines and wrinkles with water-binding properties to help restore the skin’s health and
make the barrier full functioning.
• TOCOPHERYL ACETATE: It offers significant antioxidant properties to help defend from pollution and
other environmental stressors that would otherwise weaken skin, causing unwanted changes.
• UNICLAY: biotech ingredient is a fermentation-based extract derived from a clay microorganism that
mimics the effects of clay on the skin; offers cleaner, smoother and more beautiful skin for all
ethnicities and improved sense of well-being.
References:
1. How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients? Jacquelyn Levin, DO and Saira B.
Momin, DO. J Clin Aesthet Dermatol. 2010 Feb; 3(2): 22–41.
2. Superior Efficacy of an Herbal-based Cosmeceutical Compared With Common Prescription and Cosmetic Antiaging
Therapies. Carl R Thornfeldt, Ronald L Rizer. J Drugs Dermatol. 2016 Feb;15(2):218-23.
3. Bioactive compounds from natural resources against skin aging. Pulok K. Mukherjeea,∗, Niladri Maitya, Neelesh K.
Nemaa, Birendra K. Sarkarb. a School of Natural Product Studies, Department of Pharmaceutical Technology,
Jadavpur University, Kolkata 700032, India
4. The Use of Botanical Extracts as Topical Skin-Lightening Agents for the Improvement of Skin Pigmentation
Disorders. Wenyuan Zhu1 and Jie Gao. 1Journal of Investigative Dermatology Symposium Proceedings (2008) 13,
20–24; doi:10.1038/jidsymp.2008.8
5. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1; 4(3): 253–258. doi:
10.4161/derm.21923. Eleni Papakonstantinou, Michael Roth, George Karakiulakis.
6. Type VI collagen microfibrils: evidence for a structural association with hyaluronan. J Cell Biol. 1992;118:979-90.
Kielty CM, Whittaker SP, Grant ME, Shuttleworth CA.
7. 1456 Tensor effect of anigozanthos flavidus flower extract: Modulation of tenascin-X to regenerate the skin.
Jonven Janet Attia, University of Rochester. M. Shortt. I. Lacasse. Estelle Loing. May 2018. Journal of Investigative
Dermatology 138(5):S247. DOI:10.1016/j.jid.2018.03.1474
8. Cichorium intybus root extract: A "vitamin D-like" active ingredient to improve skin barrier function. J Dermatolog
Treat, 2017 Feb;28(1):78-81. doi: 10.1080/09546634.2016.1178695. Epub 2016 May 10. P M B G Maia Campos, D
G Mercurio, M O Melo, B Closs-Gonthier.
9. Evaluation of the antioxidative capability of commonly used antioxidants in dermocosmetics by in vivo detection
of protein carbonylation in human stratum corneum. J Photochem Photobiol B. (2012) Tsai FJ, et. al.
10. In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation. Cutan Ocul Toxicol. 2015
Mar;34(1):46-52. doi: 10.3109/15569527.2014.894521. Epub 2014 Apr 22. Margaret E K Kraeling 1 , Wanlong
Zhou, Perry Wang, Oluwatosin A Ogunsola.
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