Nutrition Science and Practice Guide
Nutrition Science and Practice Guide
CRUZ
CARBOHYDRATES 2/1/2021 - found in glucose from lactose - meaning DIETARY FIBERS
after the lactose has been digest and Insoluble fibers
- The chief and cheapest source of energy absorbed, galactose arrives in the liver - cellulose, hemicellulose, lignins- cabbage,
Glucose- sole source of energy for brain 2. Disaccharides- formed when two cereals, wholegrains breads
and nerve tissue monosaccharides combine
Kotse ka ghorl a. Sucrose Soluble fibers
Glycogen-stored form of energy in liver b. Lactose Pectins- apples, citrus fruits, strawberries,
and muscles c. Maltose carrots
- Glycogen stores are depleted in about 18 hours Sucrose- glucose + fructose Gum and mucilages - oats, dried beans,
- found naturally in sugarcane, sugar beets, legumes
CLASSIFICATIONS OF CHO honey, and maple sugar
Simple carbohydrates Lactose- glucose + galactose during synthesis of milk
1. Monosaccharides- glucose, fructose, and - improves the absorption of calcium and
galactose other minerals in the body
2. Disaccharides- sucrose, lactose, and maltose - lactose intolerance
Maltose- glucose + glucose
Complex carbohydrates - does not occur naturally, formed from the
3. Polysaccharides- starches (amylose and enzymatic breakdown of starch
amylopectin), glycogen, complex most fibers - plays an important role in the beer and
liquor industry
SIMPLE CARBOHYDRATES
1. Monosaccharide - simple sugar units COMPLEX CARBOHYDRATES
- five and six carbon atom monosaccharde - single unit sugars that are bonded together to form
units a chain FUNCTIONAL FIBERS AND TOTAL FIBERS
- pentose 5 carbon atoms componenrs of - may contain 1000 or more glucose unit Functional fiber- added to foods that has been shown
nucleic acids (ribose, deoxyribose) - “ starch” to provide health benefits
- hexose 6 carbon atoms - two forms of starch digestible by humans Total fiber- combination of dietary foods and
Glucose- 6 Carbon Amylose- long, straight chain of glucose units, functional fiber in food.
- major monosaccharide found in the body comprise about 20% of the digestible starch found in
- “dextrose” vegetables, beans, breads, pasta, etc.
-Common source- from digestion of starches Amylopectin- digested more rapidly and raises
and sucrose ( common table sugar) from blood glucose much more rapidly than amylase.
our food
- source of fuel for cells Fibers- non-starch polysaccharides
Fructose - fruit sugar - group of substances with similar
- 6 carbon monosaccharide that usually characteristics
exists in a ring form -cellulose
- absorbed by the small intestine and then - hemicellulose
transported to the liver - pectins
- sweetest among monosaccharides - gums
- soft drinks, candies, jams, jellies, fruit - mucilages
Galactose - lignin (non- CHO)
- nearly the same structure of glucose - “dietary fibers” found in back of pack
CADA
Maltose- maltase - Role of microorganisms - Inadequate volume of saliva would decrease
Sucrose- sucrase - streptococcus sanguis the amount of natural buffers in the oral
Lactose- lactase - streptococcus mutans environment
Lactose intolerance- insufficient production of lactase - actinomycoses viscoses - may buffer substance sa saliva,
kaya na poop ng malambot, yurmie - lactobacillus acidophilus (pangalan palang
acidic na) Dental Plaque Bacteria:
RECOMMENDED DAILY INTAKE FOR CARBOHYRATES - Dental plaque is a sticky, jelly-like mass that
130 grams per day for adults - Role of acids may cover the enamel on all the surfaces
- many of the microorganisms in the oral
PROBLEMS WITH HIGH- SUGAR DIETS cavity were capable of producing acids Fermentable Carbohydrates:
- Caries - leptothrix buccalis - Concentration of sugar in a food- Key Factor
DENTAL CAREIS - Role of dental plaque Time for Caries Lesion to develop & Frequency of
- Erosion in the surface of a tooth caused by acids “ Gelatinous plaque of the caries fungus in a Between - Meal Snack:
made by bacteria as they metabolize sugars thin, transparent film that usually escapes - 18 months +/- 6 months- incipient attack to
- Worst offenders: sticky and gummy foods rich on observation, and which is revealed only bu clinically detectable caries
sugars careful search” - Patients with xerostomia - 3 months
- The pH is about 7.1 in caries free individuals - Between meal snack = caries
and approximately 5.5 in individuals with high susceptibility
DENTAL CARIES 2/08/2021 caries activity. Decrease saliva higher chance of caries bc of pH
Miller’s Chemicoparasitic Theory/Acidogenic Theory FACTORS IN THE DENTAL CARIES PROCESS CARIOGENIC POTENTIAL OF FOOD
- Willoughby Miller in 1882 - Tooth Chemistry/ Structures - A food is classified as potential potential cariogenic if,
Dental caries is a two (2) stage process - Amount of Salivary flow when it comes in contact with the plaque bacteria, the
Demineralization of inorganic - Types of Dental Plaque Bacteria plaque pH falls below 5.5
structures bacteria or “parasitic” - Types of Fermentable CHO eaten - Non- cariogenic food, with pH of 6 & above
phase-dissolution of albuminous - Frequency of Daily Food intake -cheeses, high protein
substances & digestive action of
bacteria Tooth Structures: RELATIONSHIP OF SUGAR ALCOHOL TO DENTAL
- Role of carbohydrates - Internal structures of the enamel - fluoride CARIES
- Role of microorganisms to make the enamel stronger for kidz onli - Have little or no effect on plaque pH
- Role of acids - Susceptible surfaces - pits & fissures , buccal - E.g. sorbitol-containing chewing gum may not
- Roles of dental plaque pits & grooves, proximal surfaces, lingual pits- contribute significantly to tooth decay
-Role of Carbohydraes food gets stuck here easily - Xylitol is very popular today as the sweetener for
- Slow clearance rate from the oral cavity are - Alignment of teeth - crowding ad sugar-free chewing gum (slenda sugar, etc)
more carcinogenc overlapping teeth , rotated teeth
- Polysaccharides are less easily fermented by (orthodontics lower the case of caries RELATIONSHIP OF SUGAR-RICH FOOD TO DENTAL
plaque bacteria than monosaccharides and production) CARIES
disaccharides - Sucrose “most-cariogenic”
- Sucrose is readily fermented by mainly Saliva: - Fructose & glucose are also cariogenic
Streptococcus mutans - Inadequate salivary flow can interfere with - Physical form of the sugar in which they are ingested
- The pH of plaque falls to 4.5-5 in about 1-3 proper oral clearance of carcinogenic influences its cariogenicity.
minutes of sugar intake. substrates
CADA
NURSING BOTTLE CARIES
- Falling asleep with the feeding bottle in the mouth of
children over long period of time
- Milk, Juices, sweetened drinks
Sealant repair para di maging catch basin for food
debris
CADA
LIPIDS the serving is 30 g or less or 2 - increases the risk of heart diseases
- group of compounds that are not uniform in tablespoons or less, 5 g of the food E.g. margarines, chips, doughnuts, cookies,
composition - Reduced or less cholesterol: at least crackers cakes, fries, and fried foods
- 9kcal/gram 25% less cholesterol and 2 g or less of
1. True fats saturated fat per serving than
2. Substances whose molecular structure reference food
includes fatty acids or fatty acid derivatives
3. Compounds present in minor amounts LIPIDS “FATTY ACID”
associated in nature - Basic structural unit
Further categorized as: * classifications according to degree of
1. Visible fats- butter, lard, margarine saturation
2. Invisible fats- marbleized fat in roast beef, butterfat, 1. Fully saturated (stearic acid)
milk, oil in avocado, potato chips, ice cream 2. Monosaturated (oleic acid -9)
3. Polyunsaturated (alpha-linolenic
Triacylglycerol acid -3 & linoleic acid -6)
- Carbon
- Hydrogen KULANG NEED SC 1. Fully saturated
- Oxygen - carbon atoms connected to hydrogen
atoms by a single bond CLASSES OF LIPIDS: TRIACYGLYCERIDS
DEFINITIONS FOR NUTRITIONAL CLAIMS ABOUT FAT A. Stearic acid - beef and lard - 18 - glycerol + 3 fatty acids
AND CHOLESTEROL OF FOOD LABELS carbons - most common fat that is present in animal or
FAT B. Palmitic acids - animal fat and palm protein food
- Fat free: less than 0.5 g of fat per serving oil - 16 carbons - primary form of fat in the body
- Saturated fat free: less than 0.5 g per serving, C. Lauric acid - milk and coconut oil - -> storage of energy, protects certain
and the level of trans fatty acids does not 12 carbons organs, transport fat-soluble vitamins,
exceed 0.5 g per serving and helps insulate the body
- Low fat: 3 g or less per serving and, if the 2. Monosaturated
serving is 30 g or less or 2 tablespoons or less, - one or more free bonds CLASSES OF LIPIDS: PHOSPHOLIPIDS
per 50 g of the food, 2% milk can no longer be - “not fully saturated” - contains phosphorus and nitrogenous base in
labeled low fat, as it exceeds 3 g per serving. - has one reactive unsaturated linkage addition to glycerol and fatty acids
Reduced fat will be the term used instead or one double bond and no hydrogen - allows fat-soluble substances (including
- Low saturated fat: 1 g or less per serving and atom vitamins and hormones) to easily pass in and
not more than 15% of local from saturated A. Palmitoleic acid out of the cell
fatty acids B. Oleic acid - olive oil, shortenings, - keep fats suspended in the blood and body
- Reduced or less fat: at least 25% less per lard, peanut oil, lamb, and poultry fat fluids since they are uniquely water soluble
serving than reference food
- Reduced or less saturated fat: at least 25% less 3. Polyunsaturated Sub-groups:
per serving than reference food - 2 or more double bonds per molecule 1. Phosphatides - part of cell walls and mitochondria
A. Linoleic acid - essential fatty acid A. Lecithin - composed of glycerol, fatty acid,
CHOLESTEROL (EFA) found in soybean, cottonseed, and choline
- Cholesterol free: less than 2 milligrams (mg) and other vegetable oils B. Cephalin - present in thromboplastin
of cholesterol and 2 g or less of saturated fat
per serving TRANS-FATTY ACIDS
- Low cholesterol: 20 mg or less cholesterol - unsaturated fatty acid that have
and 2 g less of saturated fat per serving and , if become hydrogenated
DNU MIDTERM
2. Plasmalogens - are commonly found in cell CHYLOMICRONS
membranes in the nervous, immune and cardiovascular Arachidonic Acid - Formed in the absorptive cells of the small
system - Not naturally found in humans intestine after fat absorption and travel
through the lymphatic system to the blood
3. Sphingomyelins - a component of fat-like sheath DEFICIENCY OF LINOLEIC ACID SIGNS AND stream
substance SYMPTOMS: - Chylomicrons enter the lymphatic system then
- Scaly skin into the bloodstream
CLASSES OF LIPIDS: CHOLESTEROL - Sparse hair growth - It is surrounded by large droplets of lipid
- fat-like, waxy substance classified as sterol - Poor wound healing surrounded by thin, water-soluble shell
- most of the time, intake of cholesterol is not - Thrombocytopenia
needed Good sources of linoleic acid – corn, cottonseed,
- constituent of brain and nerve tissue, bile peanut, soybean, safflower oils
salts, precursors of Vitamin D
- risk factor : atherosclerosis LIPIDS: DIGESTION AND ABSORPTION
- only 1.5 to 2 g of cholesterol in the body is - Fatty foods stimulates
synthesized per day “enterogastrone”
- high intake of cholesterol raises the total - It inhibits gastric motility and retards
plasma cholesterol level the discharge of food from the
stomach
ATHEROSCLEROSIS “GOOD” and “BAD” cholesterol in the bloodstream
- refers to the buildup of fats, cholesterol and other LIPIDS: METABOLISM AND STORAGE LDL – bad
substances in and on your artery walls (plaque), which *Liver plays an important role in fat HDL - good
can restrict blood flow metabolism by: All fats are not cariogenic but in fact it protects tooth
- Atheromata - deposits of lipids “plaque” - Synthesizing triglycerides from CHO from dental caries bec it forms a protective layer
- Synthesizing cholesterol from
LIPOPROTEINS triglycerides PROTEIN
- carriers of cholesterol and other fatty substances in - Synthesizing phospholipids and - Form important structures of the body
the bloodstream lipoprotein from proteins - Building blocks of the body
1. LDL - low - density lipoprotein - Clearing phospholipid, cholesterol, - Daily protein intake comes from animal
2. HDL - high-density lipoprotein and lipoprotein form plasma sources (milk, meat, egg)
*storage – adipose tissue under the skin - Can also come from vegetables like nuts
ESSENTIAL FATTY ACIDS (EFA) - Large complex molecules basically contain
Functions: CARRYING LIPIDS IN THE BLOODSTREAM CARBON, HYDROGEN, OXYGEN, and
1. Maintain the function and integrity of cell - Lipoproteins - serves as vehicle for NITROGEN arranged into amino acids
membranes transport of lipids from the small - Can also come from phosphorus, sulfur, copper,
2. Used to esterify cholesterol in plasma intestine and liver to the body tissue manganese
3. Required for the metabolism of cholesterol and - Precursor of antibodies and are also essential
other lipids components of enzymes and hormones
- Half of the body weight is protein
Linoleic Acid → 1/3 body protein is found in muscles
- Precursors for a group of hormone like → 1/5 is found in bone and cartilage
compounds “Prostaglandins” → 1/10 skin
- (Prostaglandins: for contraction of certain - Crucial to the regulation and maintenance of
muscles) the body
DNU MIDTERM
PROTEIN: AMINO ACIDS - Nonessential amino acids do not need
- Building block of protein to be supplied from the diet
- Each amino acid has an “acid” group, “amino”
group, and “side” group
- Branch chain amino acids: Leucine, Isoleucine,
and Valine (these three are found in WHEY)
PROTEIN-CALORIE MALNUTRITION
Kwashiorkor
Common symptoms:
→ Apathy
→ Diarrhea
→ Failure to grow and gain weight
→ Withdrawal from environment
Further symptoms:
DNU MIDTERM
WATER & ELECTROLYTES Major electrolytes as long as 10 weeks, but without H2O, life would be
Drink Ur Water Bhie
- Na. K. cl over in a matter of days”
- Mg, ca “second to O2 in importance to the body”
* Pag mineral water lang
Non electrolytes WATER RDA
- Glucose & urea in small amount 6-8 8oz glasses of H2o daily
- universal solvent
2 liters or 2 quarts daily
- w/o water it will not take place
WATER FUNCTION Depend on the following:
- cant live w/o u (water)
Promote body processes by acting as solvent - Age
- Digestion, absorption, circulatory, - Body size - determined per kg = 1 ml/kg
WATER
excretion etc for adult
component of the fluid tissues of the body
Build tissues- part of tissue structures - Infant 1.5ml/kg
-blood plasma
- Bone - /13 H2O - Activity level
- lymph
- muscle - 2/3 H2O - Diet
- interstitial fluids surrounding cells
- whole body- 4/5 H2O Additional for infant because of the
carries dissolved proteins & inorganic salts
Regulate body temperature high protein formulas
65-70% total body weight
- Evaporation from the skin & elimination Additional for patients who are/ have
- Higher in infants, male & athletes
from the lungs coma, fever, polyuria, vomiting,
Play an important role in cushioning the joint & diarrhea & taking
WATER DISTRIBUTION
internal organ Climate in which you live
60% intracellular fluid
Lubricate body tissues - warm or hot environment
40 extracellular fluid
- Eyes, lungs & air passages
Interstitial fluid- water that surrounds the
Protects fetus during pregnancy WATER SOURCES
cells of the tissues
Helps kidney to function normally Liquid
Blood plasma & lymph of the circulatory
Helps maintain electrolyte balance - Water hot tea, coffee, juices, soups
system
Play an active role in the hydrolysis of nutrient Solid
- Fruits & vegetables 80 - 95% H2O
ELECTROLYTES
“of all the essential nutrients, H2O is the most - cooked pasta- 60% H2O
mineral or compounds in water
critical, we can survive on our body’s stored food for - meat- 50% water
Conduct electricity by means of their ions
- Bread - 30 % H2O by weight
DNU MT
Water sources resulting from the oxidation of SALIVA ELECTROLYTE
dietary CHO, CHON & fats Clear, alkaline, somewhat viscid secretion from Electrolytes are minerls in your blood and
te parotid, submandibular, sublingual & other other body fluids that carry an electrical charge
WATER BALANCE smaller mucous glands of the mouth Electrolytes exist in the blood as acids, bases,
The maintenance of a normal fluid environment SALIVA FUNCTIONS and slats (such as sodium, calcium, potassium,
within the body maintains proper bodily H2O balance chlorine, magnesium, and bicarbonate). they
Depends on a balance between intake & output aids in lubrication & swallowing of food can be measured by laboratory studies of the
acts as buffer and neutralize acid in the oral blood.
WATER INTAKE cavity after eating
Performed in H2O in liquids (main source) affects the dental caries formation ELECTROLYTES
- H2O & other beverages 1. Sodium (NA-)
- 1,200 ml -1, 500 ml/day SALIVARY COMPOSITION 2. Potassium (K+)
Performed H2O in food One liter of saliva consists of: 3. Chloride (Cl)
- 700-100ml/ day - fruits & vegetables 994 g of H2O
Product of oxidation 3 g of organic materials 1. SODIUM
- 200-300ml/day Mucin, serum albumins, globulin, lysozyme essential nutrient
- 100g of fat produces 107 g of H2O 2 g inorganic materials Maintains extracellular fluid volumes cellular
Na, K, P, CA, Cl, CO2, etc osmotic pressures
WATER OUTPUT 1 g of suspended material Aids in the transmission of nerve impulses
Leaves the body through: Epithelial cells, disintegrated leukocytes, permeability of cell membrane & muscle
Kidney - 1-2 liters oral bacteria, yeast contraction
Skin - 350 ml requirements vary from one person to another
Lungs - 350 ml SALIVARY FLOW RATE - Age
Feces- 150-200 ml Buffering capacity - environmental temperature
2,600 ml As flow rate increases, electrolytes, protein - Humidity
Urine 1500 ml concentration & pH increases - amount of physical activity
Stool- 100ml Proteins & vegetables increases the buffering Minimum dietary intake of sodium of
Insensible H20- 900ml capacity 200mg/day is necessary to maintain
CHO decreases the buffering capacity physiological balance in adults
- 0.5 g NaCl or salt = 39% NA
DNU MT
Safe & adequate daily dietary intake Low sodium - 140 mg or less per serving Manifested by:
- 1100-3000 mg of NA Reduce sodium - 75% reduction in sodium - Muscle weakness
- Food & nutrition board content - Paralysis, reduced or absence if reflexes
Unsalted, no salt added & without salt - no salt - Mental confusion
SODIUM BALANCE was used in food preservation - Cardiovascular signs :ECG changes, poor
Maintained by renal and hormonal mechanisms pulse & weak heart sounds
in the kidney & adrenal glands 2. POTASSIUM
Sources: Principal cation in intracellular fluid POTASSIUM EXCESS
- Table salt Present in very small amounts in the Result from sudden increases in intake of about
- Condiments like soy sauce, fish extracellular fluid 18 g of potassium by an adult
sauce(patis) , seasoning etc Present in meat, milk & many fruits such as This can cause fatal cardiac arrest
- Foods that are cured : ham, sausages, banana apples, pears
corned beef Intracellular potassium is essential in many 3. CHLORIDE
- Preserved food cellular enzymatic function: Predominantly anion in the extracellular fluid
- Pre-mixed sauces, canned goods, etc - Glycogen synthesis Is almost entirely absent within the cells
Uses: - Glucose degradation Appears in combination with sodium &
- Flavoring agents - Amino acid uptake potassium cations
- Raises the boiling point of water Chief function of extracellular potassium is to The highest concentrations:
- Lower the freezing point of water when control cardiac function & muscle and nerve - Found in the secretion of the git
making ice cream irritability - Found in the cerebrospinal fluid
- used as preservatives Component if HCL in gastric juice
Kosher foods POTASSIUM RDA - HCL=important in initiating protein
Suppressing growth of bacteria - Least 3500 mg per day through food digestion
- can dehydrate some vegetables Low concentrations
- Help to cure meat POTASSIUM DEFICIENCY - muscle
- Control texture of foods: cheese Unlikely to occur, because of many sources - nerve tissues
- Regulates fermentation of yeast in bakery Occur from prolong potassium-free diet or from Functions:
products excessive losses resulting from diarrhea, - To regulate the osmotic pressure and
Sodium free - less tha 5 mg per serving diabetic acidosis or use of rugs such as diuretics, water balance in the body
Very low sodium - 35 mg or less per serving steroid or purgatives
DNU MT
- Acts as a coenzyme in the digestive - Low CHO, high protein or high fat diet will
process lose large amount of water from excessive
- To maintain the acid-base balance of the oxidation of body fat
blood - Denture wearer= looseness of dentures
- Also aids in the preservation of the - Decrease salivary flow = xerostomia (dry
potassium mouth)
- Burning sensation of the mouth
CHLORIDE DEFICIENCY - Dental caries & gingival irritation
ENERGY-RELEASING: do not provide the body with
Causes: Edema
fuel for energy, but without it, the body lacks energy.
- Starvation, fever, diarrhea, excessive - Retain water
B-group vitamins are needed to help the body to use
vomiting & excessive sweating - Denture wearer will tend to have pressure-
the energy-yielding nutrients (such as
Marked loss, together with potassium induced sore spots on the underlying
carbohydrates, fat and protein) for fuel.
Result to hypokalemic alkalosis swollen tissue
HEMATOPOIETIC: needed to help cells to multiply
Decrease in chloride concentration in the
extracellular fluid, increasing the bicarbonate B COMPLEX VITAMINS
concentration, will lead to a state of alkalosis RECALL: VITAMIN B1 (Thiamine)
(accumulation of base) Vitamins naturally occur in food and are needed in
1) Provides energy for the brain
Cl & K supplements to correct the deficiency very small amounts for various bodily functions.
2) Improvement of neurotransmitters
DEPARTMENT OF HEALTH & HUMAN SERVICES,
3) Proper function of the heart muscles
CHLORIDE RDA STATE GOVERNMENT OF VICTORIA, AUSTRALIA
4) Maintenance of smooth skeletal muscle
Daily chloride intake is about 2-3 g
Food sources: Thiamin ( B 1 )
VITAMIN B2 (RIBOFLAVIN)
- Table salts=sodium Riboflavin ( B 2 )
1) Aids in healthy fetal development
- Dairy & meat products Niacin ( B 3 )
2) Boosts mineral absorption in the body
- Fruits & vegetables Pantothenic acid ( B 5 )
3) Strengthens immune and digestive system
Pyridoxine ( B 6 )
EFFECTS OF ATER & ELECTROLYTE ON ORAL Biotin ( B 7 )
VITAMIN B3 (NIACIN)
HEALTH Folate or ‘folic acid’ when included in supplements
1) Supports nervous and digestive system
Dehydration (B9)
2) For normal growth and healthy skin
Cyanocobalamin ( B 1 2)
3) Vital for energy release in tissues and cells
DNU MT
VITAMIN B5 (PANTOTHENIC ACID) - Pork - Fortified Cereals
1) Contributes to a reduction in tiredness and - Fish - Banana
fatigue - Green Peas
2) Helps release energy from food - Yogurt VITAMIN B7 (BIOTIN)
3) Helps to increase hemoglobin level Beef Liver
VITAMIN B2 (RIBOFLAVIN) - Avocado
VITAMIN B6 (PYRIDOXINE) - Dairy Milk - Pork
1) Assist the body in protein metabolism - Yogurt - Sweet Potato
2) Helps to produce red blood cells - Cheese
vitamin b7 (Biotin)) Lowering blood glucose - Eggs VITAMIN B9 (FOLIC ACID)
2) Maintains healthy hair, skin, and nails - Lean Beef and Pork - Beans
3) Lowers cholesterol - Peanuts
VITAMIN B3 (NIACIN) - Whole Grain
VITAMIN B9 (FOLIC ACID) Red Meat - Beef, Beef Liver and Pork - Seafood
1) Prevention of birth defects and pregnancy - Poultry - Egg
complications - Fish
2) Promotion of brain health - Brown Rice VITAMIN B12
3) Adjunctive treatment of mental health disorders - Fortified Cereals and Bread - Fish
4) Reduction of health risk factors - Red Meat
VITAMIN B5 (PANTOTHENIC ACID) - Egg
VITAMIN B12 - Fortified Cereals - Poultry
1) DNA synthesis - Organ Meat - Milk
2) Energy metabolism - Beef - Cheese
3) Lipid metabolism - Chicken Breast - Yogurt
4) Messenger substances - Mushrooms
5) Detoxification Conditions Associated with Vitamin B Deficiency
VITAMIN B6 (PYRIDOXINE) Beriberi
FOOD SOURCES AND DEFICIENCY - Beef Liver - Caused by Vitamin B1 (Thiamine deficiency)
VITAMIN B1 (Thiamine) - Tuna - Has 2 types: Dry Beriberi and Wet Beriberi
- Fortified Breakfast Cereals - Poultry Overall Symptoms Include:
DNU MT
- Shortness of breath - Nausea Adolesce Men 14 years and older – { HYPERLINK
- Rapid Heart Rate - Vomiting nts and "https://medlineplus.gov/druginfo/natu
- Decreased Muscle Function in the lower - Thinning Hair adults ral/965.html" }
leg - Brittle Nails Females 14-18 years – 1mg/daily
- Fatigue Pregnant women – 1.4mg/daily
ARIBOFLAVINOSIS - Muscle Pain Breastfeeding women – 1.5mg/daily
- People with kidney disease and undergoing dialysis
has great risk of developing this condition RECOMMENDED DAILY
Symptoms Include: ALLOWANCE
- Sore Lips / Throat RDAs, or recommended dietary allowances, are Riboflavin (Vitamin B2)
- Redness / Swelling of mouth and throat recommendations established by the National Infants 0-6 months – 0.3mg/daily
- Angular Stomatitis Academy of Sciences' Institute of Medicine's Food 7-12 months – 0.4mg/daily
and Nutrition Board. RDAs refer to vitamins and Children 1-3 years – 0.5mg/daily
Pellagra minerals derived from food and supplements taken 4-8 years – 0.6mg/daily
Caused by the inability of body to absorb Niacin on a regular basis. The aim of these 9-13 years – 0.9mg/daily
Most Common Symptoms Include: recommendations is to show you how much of a
- Diarrhea particular nutrient your body requires on a daily Adolesce Males 14-18 years – 1.3mg/daily
- Dermatitis basis. nts and Females 14-18 years – 1mg/daily
- Dementia adults Women 18 years and over – 1.1mg/daily
Thiamine (Vitamin B1) Pregnant women – 1.4mg/daily
Peripheral Neuropathy Infants 0-6 months – 0.2mg/daily Breastfeeding women – { HYPERLINK
- Similar to Pellagra 7-12 months – 0.3mg/daily "https://medlineplus.gov/druginfo/natu
- accompanied by anemia and seizures ral/957.html" }
Children 1-3 years – 0.5mg/daily
- Focused on nerve damage
4-8 years – 0.6mg/daily
- Can impair Muscle movement
Boys 9-13 years – 0.9mg/daily
Girls 9-13 years – 0.9mg/daily
Other Vitamin B Deficiency Symptoms
- Headache
Niacin (Vitamin B3)
- Irritability
- Disturbed Sleep
DNU MT
Infants 0-6 months – 2mg/daily ral/313.html" } Infants 0-12 months – 7mcg/daily
7-12 months – 4mg/daily Children 1-3 years – 8mcg/daily
4-8 years – 12mcg/daily
Children 1-3 years – 6mg/daily
9-13 years – 20mcg/daily
4-8 years – 8mg/daily
9-13 years – 12mg/daily
Adults and Males and females 14-18 years –
Pyridoxine (Vitamin B6) adolescents 25mcg/daily
Adolesce Males 14-18 years and over –
Infants 0-6 months – 0.1mg/daily Men and women over 18 and
nts and 16mg/daily
7-12 months – 0.3mg/daily pregnant women – 30mcg/daily
adults Females 14-18 years and over –
Children 1-3 years – 0.5mg/daily Breastfeeding women –
14mg/daily
4-8 years – 0.6mg/daily 35mcg/daily
Pregnant women – 18mg/daily
9-13 years – 1mg/daily Folate and Folic Acid (Vitamin B9)
Breastfeeding women – { HYPERLINK
"https://medlineplus.gov/druginfo/natu Infants (there is 0-6 months – 65mcg/daily
ral/924.html" } Adolesce Males 14-50 years – 1.3mg/daily no RDA for 7-12 months – 80mcg/daily
nts and Females 14-18 years – { HYPERLINK infants)
adults "https://medlineplus.gov/druginfo/natu Children (RDA) 1-3 years – 150mcg/daily
Pantothenic Acid (Vitamin B5)
ral/853.html" } 4-8 years – 200mcg/daily
Infants 0-6 months – 1.7mg/daily
Men 50 years and over – 1.7mg/daily 9-13 years – 300mcg/daily
7-12 months – 1.8mg/daily
Women 50 years and over – 1.5mg/daily
Pregnant women – 1.9mg/daily
Breastfeeding women – 2mg/daily
Children 1-3 years – 2mg/daily
4-8 years – 3mg/daily
9-13 years – 4mg/daily Biotin (Vitamin B7)
Biotin is made in the body and there is insufficient
Adolesce Men and women 14 years and older – amount in food like red meat, eggs, nuts, etc and it
nts and 5mg/daily has no Recommended daily intake/allowances, but
adults Pregnant women – 6mg/daily an adequate intake (AI) is made. It is similar to the
Breastfeeding women – { HYPERLINK RDA for the vitamin B complex, it is set due to the
"https://medlineplus.gov/druginfo/natu lack of evidence to make a RDA.
DNU MT
Adolescents and Males and females 14-18 years Adolesce Males and females over the age of 14 – { (thiamine pyrophosphate) has been reported by one
adults – 400mcg/daily nts and HYPERLINK study to have a major role in dental caries due to
Men and women 18 years and adults "https://medlineplus.gov/ency/article/ accumulation of pyruvic acid in tissue.
over – 400mcg DFE/daily 002403.htm" }
Pregnant women – 600mcg Pregnant teens and women – Pyridoxine (Vitamin B6)
DFE/daily 2.6mcg/daily Pyridoxine deficiency leads to
Breastfeeding women – Breastfeeding teens and women – increased caries incidence.
500mcg DFE/daily 2.8mcg/daily
Women capable of becoming Other B vitamins
pregnant – 400mcg/daily VITAMIN B COMPLEX OVERDOSE Other B vitamins that have a role in caries formation
Pregnant women with a Niacin flush are biotin, pantothenic acid, folic acid, and inositol.
previous history of neural tube ‒ hot, burning sensation in the face High saliva folic acid level promotes the
defects – 4mg/daily ‒ Caused by too much vitamin B3 (niacin) development of caries and increased levels of
‒ Liver can become damaged inositol
Vitamin B6. acts as cariostatic
Peripheral neuropathy - loss of feeling in the arms
and legs, as well as muscle weakness, can occur as a
result of nerve damage
PREVENTIONS
‒ Drinking more water should also help to flush
out your body and help you recover from an
overdose
‒ The key is to learn how much vitamin C you
TREATMENT
really need.
Vitamin C supplements & citrus fruits
DNU MT
FAT SOLUBLE VITAMINS A,D,E,K ‒ Tocotrienols: alpha-tocotrienol, beta- ‒ A person can obtain some vitamin D from the
‒ Fat soluble vitamins tocotrienol, gamma-tocotrienol and delta- sun
‒ Are similar to oil and do not dissolve in water tocotrienol
‒ Most abundant in high-fat food and are much Alpha-tocopherol is the most common form of Vitamin E
better absorbed into your bloodstream when Vitamin E ‒ Found in plant-based oils,nuts, seeds, fruits, and
you eat them with fat vegetables
‒ Stored in the body’s fatty tissue and in the liver Vitamin K ‒ Wheat germ oil, sunflower (sunflower
‒ Helps to form blood clots seeds),safflower, and soybean oil, almonds,
Vitamins: ‒ Vitamin K1(phylloquinone): found in plant- peanuts(peanut butter), beef greens, collard
Vitamin A sourced foods; it is the main form of Vitamin K greens, spinach
‒ Known as retinol in the diet
‒ Associated with vision and eye health ‒ Vitamin K2(menaquinone) found in animal- Vitamin K
‒ Studied in the prevention and treatment of sourced foods and fermented soy products, like ‒ Vitamin K1 - found in leafy green vegetables
some types of cancers natto; also produced by gut bacteria in the (spinach, broccoli, brussels sprouts, cabbage,
colon lettuces, soybeans and canola oil)
Vitamin D ‒ Synthetic forms: K3 (menadione), vitamin K4 ‒ Vitamin K2 - animal-sourced foods, such as
‒ Sunshine vitamin (menadiol diacetate) and vitamin K5 liver, butter and egg yolks
‒ D2 (ergocalciferol): in mushrooms and some
plants FOOD SOURCES FUNCTIONS OF EACH VITAMINS
‒ D3 (cholecalciferol): in eggs and fish oil, and Vitamin A Vitamin A
produced by your skin when exposed to ‒ Cheese, carrots, yellow and orange vegetables, ‒ Maintenance if normal vision (Retinal + Opsin
sunlight. some leafty, dark-green vegetables(spinach), =RHODOPSIN)
potat, eggs, oily fish, fortified low-fat spreads, ‒ Protect and maintain the cornea and
Vitamin E milk and yogurt, liver and liver products conjunctiva
‒ Type of antioxidant ‒ Maintain surface tissues such as skin, intestine,
‒ Tocopherols: alpha-tecopherol, beta- Vitamin D lungs, bladder and inner ear
tecopherol, gamma-tecopherol and delta- ‒ Oily fish and fish oils - (such as salmon, ‒ Supporting the growth and distribution of T-
tecopherol sardines, mackarel), fortified diary products cells
(plant-based milks and cereals),beef liver, eggs, ‒ Supports healthy skin cells, male and female
mushroom reproduction and fetal development
DNU FINALS
Vitamin D ‒ Plays and integral part in promoting bone Following the consumption of Vitamin D2-
‒ Sunshine vitamin health containing food, about 80% of Vitamin D2 is
‒ Regulating the absorption of calcium and ‒ Ensures calcium-binding action required for the incorporated into micelles in the small intestine and
phosphorus, and facilitating normal immune healthy function of the bones and gums then absorbed and transported to the liver by
system function ‒ Strengthens the skeletal structure chylomicrons through lymphatic system. Patients
‒ Fights diseases (reducing the risk of multiple ‒ Treats osteoporosis and bone loss with chronic fat-malabsorption syndromes (e.g.
sclerosis, decrease the chance of developing ‒ Highly essential in improving dental health cystic fibrosis, Crohn’s disease and celiac disease)
heart disease, reduce the likelihood of have trouble absorbing Vitamin D2 and may develop
developing flu) DIGESTION, ABSORPTION AND METABOLISM a deficiency.
‒ Reduces depression Overview:
‒ Boosts weight loss ‒ Fat soluble vitamins are absorbed along with
dietary fats. Needs adequate absorption
Vitamin E ‒ Utilizes bile salts, pancreatic lipase, healthy,
‒ Protects body tissue from damage caused by intestinal wall
substances called free radicals( free radicals are ‒ Packaged and delivered to target cells in a
increased by: cigarette smoking, exposure to air similar manner to dietary fats- chylomicrons
pollution, high exposure to ultraviolet rays and other blood lipoprotein
from sunlight Vitamin E (alpha-tocopherol)
VITAMIN E
Vitamin E, just like Vitamin C, helps prevent gum
disease by doing two things: reducing inflammation
and serving as an antioxidant
DNU FINALS
MICROMINERALS: CALCIUM, PHOSPHORUS, 11. Emotional reactions The level of calcium balance in a serum is
MAGNESIUM 12. Exercise regulated by:
‒ Parathyroid hormone
CALCIUM Storage of calcium ‒ Calcitonin
Distribution of calcium ‒ Stored in the trabeculae of the long bones ‒ Vitamin D
There is about 1200g of calcium present in adult ‒ Can be withdrawn from the trabeculae from the
body body to maintain a continuous dynamic ROLE OF BONE, KIDNEY AND INTESTINE
99% (1188g) is contained in the bones and teeth equilibrium with the other minerals in the bone Bone - balance of cellular activity, osteoblast in bone
1% (12g) is found in the extracellular fluid and soft and blood production and osteoclast involve in bone
tissues and as part of various membrane structures ‒ The blood and tissue calcium act as a reserve absorption
‒ Blood within the trabeculae is responsible in Kidney - resorbs calcium, regulates the serum
Absorption of calcium transporting the calcium and phosphate salts to calcium and phosphate levels
Absorbed from the intestine by active process those tissues and structures that needs them Intestine- Helps regulate serum calcium and
requiring energy and also by passive ionic diffusion phosphate levels
in the small intestine Excretion:
Only 20-30% of calcium is absorbed and the In dietary intake of 1000g mg of calcium Role of parathyroid hormone (PTH)
remainder is excreted in the feces, urine and 700-800 mg excreted in the feces ‒ Maintains the normal level of serum calcium
perspiration. 150 mg300 mg through lactation of a mother ‒ Its secretion increases when serum calcium
15 mg daily loss through perspiration drops below 7mg/100ml
Factors influencing calcium absorption ‒ Stimulates the synthesis of 1,25-dihydroxy-
1. Needs of the body Regulation of calcium balance: cholecalciferol that causes the increased
2. Gastric acidity ‒ Calcium level is maintained at a constant absorption of calcium from the bone
3. Hormonal influences concentration of 10 mg/100ml of blood ‒ The thyroid gland releases calcitonin, if serum
4. Vitamin D ‒ 60% in ion form & is physiologically active calcium is above 10 mg/100ml, which lowers
5. Calcium to phosphate ratio ‒ 35% is bound to protein high serum calcium level.
6. Lactose ‒ 5% in complexes with citrate, bicarbonate, and ‒ Decreased in 1,25-dihydroxy-cholecalciferol
7. Citric acid phosphate leads to reduced intestinal absorption and bone
8. Dietary protein and phosphorus resorption
9. Oxalic and phytic acids
10. Fat
DNU FINAL
Role of Vitamin D ‒ 84.9% (594.3g) stored in the bone in an Absorption and Excretion
‒ For normal intestinal absorption insoluble form of calcium salt ‒ 1/3 Magnesium is absorbed and utilized by the
‒ Helps maintain bone cells, regulates serum ‒ 15% (105g) located in the cell membrane and body
calcium and serum phosphate the intracellular fluid in the soft tissues in a ‒ High intake of calcium, phosphorus, lactose
‒ Transports dietary calcium to the blood by acid form of organic phosphate interferes with absorption
mechanism ‒ 0.1% (0.7g) present in the extracellular fluid ‒ Unlike calcium, there is little excretion of Mg
through intestine
Toxicity Sources of Phosphorus ‒ Mostly stored in bone
Result to hypercalcemia: ‒ Naturally found in protein-rich foods such as ‒ Regulation of Mg in the blood depends on a
‒ Milk - alkali syndrome meats, poultry, fish, nuts, beans and diary balance between absorption and sodium
Result to high level of calcium serum and urine or products excretion
calcification of soft tissues: ‒ Lost through urine, feces, vomiting, and
‒ Idiopathic hypercalcemia of infants MAGNESIUM diarrhea
‒ Hypercalcinuria 1. One of the major cations in plant and animal
‒ Hyperthyroidism tissues Relationship of phosphate to dental caries
2. Plays an important role in the fundamental Phosphate
PHOSPHORUS enzymatic reactions and protein synthesis ‒ Chemical compound that contains phosphorus
‒ Essential mineral 3. Essential component of bone and teeth ‒ Release of energy as a result of the metabolism
‒ Components of bones, teeth, DNA, and RNA ‒ Cell protein synthesis
‒ Also a component of cell membrane and ATP Distribution of magnesium ‒ Part of the nucleic acids DNA and RNA
The body contains 20-35g of Mg ‒ Buffers
Effect of phosphorus to bone & teeth development 60% as phosphates & carbonates in bone ‒ Acid-base balance
‒ Plays an important role in how the body uses 40% other cells and soft tissues (muscles and body
carbohydrates and fats fluids) Chemistry:
‒ Phosphorus works with calcium to help build ‒ 2nd to potassium in predominant metallic cation ‒ Is a phosphate ion that is conjugate base of
bones in living cells hydrogen phosphate
‒ rd
3 most abundant mineral in teeth ‒ It is a phosphate ion and trivalent inorganic
Distribution of phosphorus ‒ Central component of chlorophyll anion
Total amount of phosphorus is 500-700g in the ‒ Anion, salt, functional group or ester derived
human body from a phosphoric acid
DNU FINAL
‒ It most commonly means orthophosphate, a Clinical trials of Phosphates added to chewing Sources and functions
derivative of orthophosphoric acid gum Calcium
Baron 1. Bone and tooth formation
DENTAL CARIES ‒ Regular gum = more dental caries 2. Nerve impulse transmission
‒ Localized demineralization ‒ Dicalcium phosphate sugar- base chewing gum 3. Muscle contraction
‒ Tooth decay is safer 4. Clotting factors
‒ Causes the breakdown of the tooth enamel
‒ Erosions of the surface of the tooth caused by Finn & Jameson Phosphorus
the combined effects of bacteria, acids, plaque ‒ Sugar gun 1. Plays a major role in structural framework of DNA
and tartar ‒ Sugarless gum and RNA
‒ Sugar gum with dicalcium phosphate additive 2. Mostly associated with calcium as a part of the
Symptoms: ‒ 20% reduction in DMFS (decayed, missing and mineral structure of bones and teeth
‒ Holes in the surface of a tooth filled surfaces) 3. It is also needed for the body to make proteins for
‒ Pain when chewing the growth, maintenance , and repair of cells and
‒ Sensitivity to hot or cold foods and beverages 3rd Clinical trial tissues.
‒ Toothache ‒ Control group not chewing any gum 4. Helps oxygen delivery in the blood
‒ Group chewing gum with dicalcium phosphate 5. Helps maintain our energy levels
Phosphate and dental caries (HISTORY) sugar
Lennox ‒ Group chewing a sugarless gum Magnesium
‒ 1931 1. Bone health
‒ White south africans Phosphate on dental caries 2. Glucose control and insulin metabolism
‒ Extensively destroyed ‒ Greatly reduces the development of 3. Cardiovascular health
‒ Phosphorus - deficient soils experimental caries 4. Migraine headaches
‒ Pit-and-fissures sealants containing amorphous
Osborn and Noriskin calcium phosphate SOURCES
‒ 1937 ‒ Repair teeth through a process known as Calcium
‒ African Bantus remineralization ‒ Cheese,seeds, yogurt, sardines and canned
‒ Unprocessed natural foods salmon, beans and lentils, leafy greens, bread,
‒ Low incidence of dental caries almonds, diary products, orange
‒ Phytates and organic phosphate
DNU FINAL
Phosphorus TYPES OF FLUORIDE Gel / foams (TOPICAL DELIVERY)
‒ Nuts, meats, fish, beans lentils, beef, squash and ‒ Systemic delivery ‒ Delivered by dentists through the use of tray
pumpkin seeds, almonds, firm tofu, diary - Water fluoridation and are seated in the mouth for a few minutes
products ‒ Topical delivery ‒ Patients should not eat/smoke for half and hour
- toothpaste for fluoride absorption
Magnesium - mouth rinse
‒ Spinach, nuts, legumes, whole grains, bananas, - gels/foams Varnish (TOPICAL DELIVERY)
leafy greens, dark chocolate, peanuts, oatmeal, - varnish ‒ Contains high fluoride concentrations applied
avocado - tablet supplements using a brush
‒ Patients are advised not to brush for the whole
FLUORIDE & THEIR ROLE IN DENTAL CARIES Water fluoridation (SYSTEMIC DELIVERY) day
PREVENTION ‒ Controlled adjustment of fluoride to a public ‒ Reapplication every 6 month is recommended
‒ Compound of fluorine with another element or water supply
radical ‒ Fluoridated water contains fluoride at a level Tablet supplements (TOPICAL DELIVERY)
‒ Fluoride containing compounds are used in effective for preventing caries ‒ Need prescription
preventing tooth decay ‒ Increases rate of remineralization in early ‒ Commonly given to those with non-fluoridated
‒ Commonly used in dentistry to strengthen stages of cavities water supply ad have high caries risk
enamel ‒ 6 month - 16 years old are carefully prescribed
‒ Mineral in the bones and teeth Toothpaste (TOPICAL DELIVERY) depending on the level of fluoride they acquire
‒ Most convenient and known delivery method
FUNCTIONS OF FLUORIDE ‒ 1,350 to 1500 ppm(PART PER MILLION) SIGNIFICANCE OF FLUORIDE IN THE
‒ Mineralization of bones and teeth (fluoride levels for adults and children no PREVENTION OF CARIES
‒ Slows down the loss of minerals from tooth younger than 3) ‒ Tooth enamel is composed of hydroxyapatite
enamel ‒ Low pH = dissolution of hydroxyapatite
‒ Reverse early signs of tooth decay Mouth rinse (TOPICAL DELIVERY) (demineralization)
‒ Protects teeth from dental caries (added in ‒ Aid in flushing out food debris and bacteria
toothpaste) ‒ Has many variants (alcohol and no alcohol) How do we prevent demineralization?
‒ Has antimicrobial effect ‒ Non-alcoholic containing are advised for ‒ One of the most effective methods of
children preventing caries is remineralization through
fluoride therapy
DNU FINAL
Remineralization ‒ It gets into the enamel through the SYSTEMIC FLUORIDE & TOPICAL FLUORIDE:
‒ Hydroxyapatite → fluorapatite (when fluoride remineralization process of the teeth SURFACE AND ACTIONS
is present in oral fluids) ‒ It forms a compound called fluorapatite Systemic Fluoride
- F⁻⁻ replace OH⁻⁻ in the formation of the ‒ Fluorapatite is Fl + Ca + PO4 ‒ It is also referred to as water fluoridation in the
apatite crystal lattice ‒ Fluorapatite is stronger and can resists decay U.S.
‒ Fluorapatite is less soluble than hydroxyapatite better than hydroxyapatite ‒ These are ingested in the body and become
even under acidic conditions incorporated into forming tooth structures.
‒ When hydroxyapatite is dissolved under ‒ It’s mechanism of action is from the topical
cariogenic conditions, fluorapatite is protection as the fluoride present in saliva
incorporated into demineralized enamel = provides a constant source that is also
demineralization is inhibited incorporated into plaque and facilitates
remineralization
‒ With fluoride treatment, a noncavitated lesion Preventive action:
can be remineralized with fluorapatite and have 1. It decreases the solubility of enamel in acid by
greater resistance to subsequent converting hydroxyapatite into less soluble
demineralization than hydroxyapatite Even fluorhydroxyapatite or fluorapatite.
when available at very low concentrations, 2. It incorporates in plaque and reduces the ability of
fluoride is effective as an anticaries agent acid production by the plaque organisms.
‒ With fluoride treatment, caries can be 3. It promotes the remineralization of enamel in
prevented. areas that have been demineralized by acids
‒ Loss of minerals can be slowed down and
reversed as well, in case of early signs of tooth ‒ Among the three mechanisms, remineralization
decay. action of fluoride is most important and
requires calcium and phosphate.
MECHANISMS OF ACTION OF FLUORIDE IN ‒ It’s cariostatic effect is attributed to the reduced
CARIES PREVENTION solubility of the enamel due to the
Fluoride mechanism incorporation of fluoride into the enamel
‒ Fluoride is easily absorbed & taken up into the minerals during tooth formation.
enamel
DNU FINAL
Sources: Fluoride mouth rinses or brush-on gels may be ‒ Hypocalcemia
Water fluoridation recommended for school aged children with active ‒ Tetany specially of hand an feet
Dietary supplements (tablets, drops, or caries or at high risk for caries. Indicators of ‒ Hypotension and hypersalivation
lozenges) increased caries risk may include: ‒ Mixed metabolic and respiratory acidosis due
Fluoride present in food and beverages ‒ Orthodontic or prosthodontic appliances to failure of renal/respiratory system
Salt and milk fluoridation ‒ Reduced salivary function ‒ Coma and convulsions leading to death
‒ Inability to clean teeth properly
Systemic fluoride such as community water ‒ Dietary risks Chronic effects
fluoridation and dietary fluoride supplements are ‒ Siblings with caries ‒ Dental fluorosis
effective in reducing tooth decay. ‒ High oral levels of cariogenic bacteria ‒ Skeletal fluorosis
‒ Hyprsenstivity reactions
TOPICAL FLUORIDE RDA & TOXICITY LEVEL ‒ Dyspepsia, gastric irritation
‒ Strengthen teeth that is already present in the ‒ Insufficiency of renal system
mouth, making them more decay resistant. ‒ Numbness, macular spasm
‒ It is applied directly to and absorbed by the ‒ Birth defects and cancer
surface of the teeth.
‒ May result in a significant reduction in caries as CONDITION RESULTING FROM
the fluoride gets integrated into the enamel EXCESSIVEFLUODE INTAKE
matrix, hardening the structure and making it Dental fluorosis
more resistant to demineralization. ‒ It is the appearance of faint white lines or
streaks on the teeth that only occurs when
Sources: younger children consume too much fluoride,
‒ Self -applied topical fluorides from any source, over long periods when teeth
- Toothpastes, mouth rinses, and gels are developing under the gums.
(contain a safe and effective concentration ‒ People with fluorosis are relatively resistant to
of fluoride to fight tooth decay) dental caries (tooth decay caused by bacteria),
‒ Professionally applied topical fluorides although there may be cosmetic concern.
- higher-strength rinses, gels, foams,
EFFECTS OF FLUORIDE TOXICTY
fluoride varnishes, and silver diamine
Acute effects
fluoride
‒ Nausea, vomiting
DNU FINAL
T3 and T4—this is a typical feature of ‒ Secondary HPT occurs when a disease outside
hypothyroidism. of the parathyroid glands causes the
‒ With prolonged fluoride exposure, the entire parathyroid glands to become hyperactive.
function of the thyroid gland can be suppressed,
causing TSH levels to diminish.
Skeletal fluorosis
‒ It is a serious condition, resulting from chronic hyperparathyroidism
ingestion of large amounts of fluoride over
many years during periods of bone modeling Neurological problems
(growth) and/or remodeling. ‒ For years health experts have been unable to
Thyroid problems: Hyperparathyroidism
‒ In skeletal fluorosis the bones are generally agree on whether fluoride in the drinking water
‒ HPT affects one or more of the parathyroid
weaker than normal with stiffness and pain in may be toxic to the developing human brain.
glands, which help the body manage its calcium
the joints as the early symptoms. ‒ Extremely high levels of fluoride are known to
levels.
cause neurotoxicity in adults, and negative
‒ The parathyroid glands produce parathyroid
impacts on memory and learning have been
hormone (PTH), which regulates calcium in the
reported in rodent studies, but little is known
blood.
about the substance’s impact on children’s
‒ If a person is dealing with HPT, the parathyroid
neurodevelopment.
glands produce excess amounts of PTH; this
causes calcium levels in the blood to rise and
“Fluoride seems to fit in with lead, mercury, and
can result in mild to severe side effects.
other poisons that cause chemical brain drain,”
Fluoride poisoning
‒ It is a condition in which there are elevated
levels of the fluoride ion in the body.
‒ Whilst fluoridated water is associated with
decreased levels of fractures in a population,
toxic levels of fluoride have been associated
with a weakening of bones and an increase in
hip and wrist fractures.
DNU FINAL
FAT SOLUBLE VITAMINS A,D,E,K ‒ Tocotrienols: alpha-tocotrienol, beta- ‒ A person can obtain some vitamin D from the
‒ Fat soluble vitamins tocotrienol, gamma-tocotrienol and delta- sun
‒ Are similar to oil and do not dissolve in water tocotrienol
‒ Most abundant in high-fat food and are much Alpha-tocopherol is the most common form of Vitamin E
better absorbed into your bloodstream when Vitamin E ‒ Found in plant-based oils,nuts, seeds, fruits, and
you eat them with fat vegetables
‒ Stored in the body’s fatty tissue and in the liver Vitamin K ‒ Wheat germ oil, sunflower (sunflower
‒ Helps to form blood clots seeds),safflower, and soybean oil, almonds,
Vitamins: ‒ Vitamin K1(phylloquinone): found in plant- peanuts(peanut butter), beef greens, collard
Vitamin A sourced foods; it is the main form of Vitamin K greens, spinach
‒ Known as retinol in the diet
‒ Associated with vision and eye health ‒ Vitamin K2(menaquinone) found in animal- Vitamin K
‒ Studied in the prevention and treatment of sourced foods and fermented soy products, like ‒ Vitamin K1 - found in leafy green vegetables
some types of cancers natto; also produced by gut bacteria in the (spinach, broccoli, brussels sprouts, cabbage,
colon lettuces, soybeans and canola oil)
Vitamin D ‒ Synthetic forms: K3 (menadione), vitamin K4 ‒ Vitamin K2 - animal-sourced foods, such as
‒ Sunshine vitamin (menadiol diacetate) and vitamin K5 liver, butter and egg yolks
‒ D2 (ergocalciferol): in mushrooms and some
plants FOOD SOURCES FUNCTIONS OF EACH VITAMINS
‒ D3 (cholecalciferol): in eggs and fish oil, and Vitamin A Vitamin A
produced by your skin when exposed to ‒ Cheese, carrots, yellow and orange vegetables, ‒ Maintenance if normal vision (Retinal + Opsin
sunlight. some leafty, dark-green vegetables(spinach), =RHODOPSIN)
potat, eggs, oily fish, fortified low-fat spreads, ‒ Protect and maintain the cornea and
Vitamin E milk and yogurt, liver and liver products conjunctiva
‒ Type of antioxidant ‒ Maintain surface tissues such as skin, intestine,
‒ Tocopherols: alpha-tecopherol, beta- Vitamin D lungs, bladder and inner ear
tecopherol, gamma-tecopherol and delta- ‒ Oily fish and fish oils - (such as salmon, ‒ Supporting the growth and distribution of T-
tecopherol sardines, mackarel), fortified diary products cells
(plant-based milks and cereals),beef liver, eggs, ‒ Supports healthy skin cells, male and female
mushroom reproduction and fetal development
DNU FINALS
Vitamin D ‒ Plays and integral part in promoting bone Following the consumption of Vitamin D2-
‒ Sunshine vitamin health containing food, about 80% of Vitamin D2 is
‒ Regulating the absorption of calcium and ‒ Ensures calcium-binding action required for the incorporated into micelles in the small intestine and
phosphorus, and facilitating normal immune healthy function of the bones and gums then absorbed and transported to the liver by
system function ‒ Strengthens the skeletal structure chylomicrons through lymphatic system. Patients
‒ Fights diseases (reducing the risk of multiple ‒ Treats osteoporosis and bone loss with chronic fat-malabsorption syndromes (e.g.
sclerosis, decrease the chance of developing ‒ Highly essential in improving dental health cystic fibrosis, Crohn’s disease and celiac disease)
heart disease, reduce the likelihood of have trouble absorbing Vitamin D2 and may develop
developing flu) DIGESTION, ABSORPTION AND METABOLISM a deficiency.
‒ Reduces depression Overview:
‒ Boosts weight loss ‒ Fat soluble vitamins are absorbed along with
dietary fats. Needs adequate absorption
Vitamin E ‒ Utilizes bile salts, pancreatic lipase, healthy,
‒ Protects body tissue from damage caused by intestinal wall
substances called free radicals( free radicals are ‒ Packaged and delivered to target cells in a
increased by: cigarette smoking, exposure to air similar manner to dietary fats- chylomicrons
pollution, high exposure to ultraviolet rays and other blood lipoprotein
from sunlight Vitamin E (alpha-tocopherol)
VITAMIN E
Vitamin E, just like Vitamin C, helps prevent gum
disease by doing two things: reducing inflammation
and serving as an antioxidant
DNU FINALS
TRACE MINERALS Cobalt is a naturally occurring element in the Boost immunity. Research shows that increased
TABLE OF CONTENTS earth's crust. It is a very small part of our selenium in the blood can speed up immune
1. DEFINITION Selenium, copper, cobalt, environment. system response
manganese Cobalt is a component of vitamin B12, which
2. IMPORTANCE Of each trace elements to the supports the production of red blood cells. COPPER
body and functions Very small amounts are needed for animals and Antioxidant properties Contains antioxidants, it
3. ROLE Of each trace elements in oral health humans to stay healthy. Cobalt poisoning can may reduce the production of free radicals
4. CONDITIONS Resulting from excessive intake of occur when you are exposed to large amounts Collagen production Help the body to replace
each elements of it. damaged connective tissues and the collagen
needed to hold bones together
1. DEFINITION Selenium, copper, cobalt, manganese MANGANESE Boost immunity Maintaining copper levels in
SELENIUM Manganese is a trace mineral that is present in the body may help with the production
An essential mineral that is a component of an tiny amounts in the body. It is found mostly in Improve cardiovascular health Helps maintain
antioxidant enzyme, glutathione reductase, that bones, the liver, kidneys, and pancreas. healthy bones, blood vessels, nerves, and
is key in tissue respiration. Manganese helps the body form connective contributes to iron absorption
Food sources of selenium include seafoods; tissue, bones, blood clotting factors, and sex
some meats, such as kidney and liver; and some hormones. COBALT
grains and seeds. Found in several foods including nuts, legumes, Production of red blood cells. Helps in the
seeds, tea, whole grains, and leafy green formation of hemoglobin; regulate and
COPPER vegetables stimulate the production of some coenzymes.
A metallic element (atomic number 29; atomic Multiple. Sclerosis Aids in the repair of myelin
weight 63.56) that is an essential trace mineral. 2. IMPORTANCE Of each trace elements to the body sheath; good for the treatment of sclerosis
It is linked to key metabolic reactions, including and functions
in iron absorption and metabolism, and the SELENIUM MANGANESE
formation of red blood cells and nerve Powerful antioxidant. Helps reduce oxidative Controls sugar level Normalizes insulin
It is present in mollusks, organ meats, nuts, stress, which can damage healthy cells. synthesis and secretion
legumes and seeds. Promotes thyroid health. Plays an important Prevents osteoporosis Essential mineral proved
role in thyroid hormone synthesis and to add to bone density and overall mineral
COBALT metabolism density
DNU FINALS
Healthy bones Essential for the proper growth IODINE (I) - functions Adequate supplementation of Selenium
of human bone structure Synthesis of thyroid hormones could produce cytoprotective effects and
Alleviates PMS Syndrome Helps to alleviate the Regulates functions of immune cells. antiulcer activity
mood swings, headaches, depression and etc. Has anticancer properties It can effectively reduce the duration and
Improves thyroid health Helps enzymes severity of oral mucositis due to its anti-
function; plays a role in the production of 4. ROLE IN ORAL HEALTH inflammatory and antioxidant effect.
thyroxine SELENIUM
COPPER
3. FUNCTIONS of trace elements; iron, chromium, It has a significant impact on the acid
fluorine, iodine solubility of enamel, which is a basic
process in the development of dental
IRON- functions caries and erosion.
supports healthy skin, hair and nails Higher caries prevalence is found to be
production of blood, hemoglobin, myoglobin, related to the existence of copper in water,
cytochromes, and other enzymes. food, soil or vegetables.
helps convert blood sugar to energy Deficiency of Cu in diet for a prolonged
boosts the immune system period especially during stages of active
growth leads to anemia and defective
CHROMIUM (Cr) - functions Decrease in the concentrations of selenium keratinisation in the oral cavity
Plays a role in immune function and growth will result in increased oxidative stress It is a part of vitamin B12 also referred to as
Assists insulin as it transports glucose from the inside the body tissues with inadvertent extrinsic factor, is essential for formation
blood into the cells harmful effects. of erythrocytes.
DNU FINALS
does not need acidic gastric The Modified MyPyramid for Older Adults Risk factors
environment Pressure ulcers
Wounds
Symptoms of Vitamin B12 deficiency Trauma
macrocytic anemia Burns
forgetfulness Sepsis
inability to concentrate Malabsorption
sensory disturbances
Malnutrition
Synthetic B12 Sources Close to 60% of hospitalized or
Dehydration
Cereal, soy milk institutionalized older persons are
Dehydration is condition caused by the loss of too
much fluid from the body. malnourished compared with close to 27%
Vitamin B6 of those living in the community
↑ Vitamin B6, ↑50 yrs Malnutrition is often manifested in the form
Signs and symptoms
female: 1.5 mg daily of unintentional weight loss in the older
Dry mouth
male: 1.7 mg daily person.
Tiredness or fatigue
Sources Factors: Poor wound healing, skeletal
Sunken eyes
Eggs, fish, chicken muscle loss, altered pharmacokinetics, and
A decrease in urination
diminished immune response
Urine that's a darker color than normal
Fluid
Muscle cramping
Recommended daily intake of water from all sources: Why Does Malnutrition Occur in Older Adults?
Feeling dizzy or lightheaded
3.7 Liters - MEN Undernutrition occurs because of three
2.7 Liters - WOMEN primary reasons:
Protein
These contributes to fluid intake but should not be o decreased intake
0.8 mg/kg body weight is needed for both
consumed in excess o increased losses of nutrients
younger and older adults. Some researchers
Beer, gins, alcoholic beverages o increased nutritional needs that go
recommend 1 mg/kg body weight per day.
unmet.
Financial constraints can lead to limitation
In almost 25% to 40% of older adults with
of protein-containing foods because of the
unintentional weight loss, no known cause
cost of many of these foods
is found
DNU FINALS
Decreased Intake GUSTATORY Nutritionally related oral problems in Elderly
Changes in appetite associated with aging ➔ Mediated through the papillae, taste buds, patients: Nutritional Anemias: Painful, Burning
o Sedation and free nerve endings found in tongue and Tongue
o altered taste in hard and soft palates in the pharynx. Pernicious anemia (Addison's anemia)
o gastrointestinal (GI) symptoms. ➔ In general, the number of these
Pain structures appears to decreased with age.
Physical conditions and disease ➔ A result of hyperkeratinization of the
o Symptoms: shortness of breath and epithelium that occludes taste bud ducts.
fatigue leave little energy for the ➔ Caused by Vitamin A inadequacy.
effort of eating
Macrocytic anemia due to Vitamin B12
Xerostomia (Dry Mouth)
deficiency
Nutritionally related oral problems in Elderly lack of saliva results to:
Lack of intrinsic factor (atrophy of the
patients ➔ Dry and often painful mucosa.
gastric mucosa)
1. Alterations in Gustation and Olfaction ➔ Hinders chewing food because it
General Symptoms:
2. Xerostomia (Dry Mouth) prevents formation of a bolus.
generalized weakness
3. Painful, Burning Tongue ➔ Make mouth sore and chewing
numbness or tingling of the extremities.
4. Oral Mucous Membrane Problems painful.
a sore, painful tongue:
5. Temporomandibular Joint Pain ➔ Make swallowing difficult
o atrophy of the papillae, dark red,
6. Alveolar Osteoporosis ➔ Causes change in taste
rather than the normal pink.
perception that decreases adequate
o oral mucosa exhibits a pale
Alteration in gustation and olfaction food intake
yellowish tinge
OLFACTION Prevention:
Treatment:
➔ Act of perceiving odors. ➔ chew sugar-free gums to
Intramuscular administration of vitamin
➔ Odors of food contribute to its stimulate flow of saliva
B12
palatability. ➔ limit caffeine intake
➔ As a person gets older, olfactory function ➔ avoid mouthwash that contains
declines. alcohol
➔ Fibers in the olfactory bulb, along with ➔ stop tobacco use
olfactory receptors decrease noticeably with ➔ drink more water
age.
DNU FINALS
Megaloblastic Anemia Glossitis white thickening of the palatal mucosa due
Angular cheilitis to hyperkeratosis
Papillary atrophy of the tongue The glandular tissue is replaced by
Treatment/Nutritional Management: connective tissue
ingesting iron-rich or enriched foods Epithelial mass increases
( liver,eggs, and cereals) Hyperkeratotic lesions on surfaces that are
Stomatitis
Nutritionally related oral problems in Elderly
Diarrhea
patients: Temporomandibular Joint Pain
General weakness Patient's chief complaints:
Temporomandibular Joint Pain
Treatment/Management:
Burning sensation, pain, and dryness of the
Due to the tooth wear that can produce
5 to 15 mg of folacin tablets daily mouth
overclosure of the jaw and affect the
Maintenance: doses of 2 to 5 mg of folacin Cheilosis
relations of the mandibular condyle to the
tablets daily
Chewing and swallowing become difficult
glenoid fossa
yeast, liver, fresh green vegetables, & fruits
Dysgeusia
Epithelial membrane is thin, friable, and Tooth wear:
Iron deficiency anemia
easily injured 1. Masticating very firm food: Over many
salivary deficiency years
Changes in the blood vessels: 2. Bruxism: teeth grinding
Atherosclerosis 3. Attrition: wearing down
Varicosities (underside of the tongue and in
occurs in elderly patients who live on a tea- the floor of the mouth) e.g. SLV Common cause of overclosure
and-toast diet Changes in Palatal Mucosa: Glenoid fossa can become shallower and
General Symptoms: head of the condyle become flatter.
DNU FINALS
Meniscus to be perforated or damaged In the elderly: Preventive Dentistry
causing pain and limitation of range of They tend to have a relative increase in “Actions taken prior to the onset of disease,
movement of the jaw bone disease and resorption which removes the possibility that a disease
Partial or complete edentulism without So, if with the loss of teeth the alveolar will ever occur”
prosthetic replacement process no longer serves its primary Objectives
Osteoarthritis is a degenerative changes function to tooth support and therefore is To avert initiation of disease process
that can produce articular disc changes reabsorbed. To intercept their progress
which create the clicking of the jaw This loss in vertical height of the bone and To control their spread
the changing of the angel of the mandible is To limit their complication and after effects
Temporary prevention of overclosure: manifested as a loss in face height in older To provide rehabilitation
1. Acrylic guard people
2. Fixed bridgework or partial dentur Scope of Preventive Dentistry
3. Select foods of medium to soft BONE DISUSE aka NON FUNCTIONAL ATROPHY Factors predisposing to disease
consistency When occlusal forces are reduced, bone is Factors encouraging the advancement of
Prevent excessive occlusal wear of resorbed, bone height is diminished, and disease
the intact dentition the number and thickness of the tuberculae Complication of disease and deformity
are reduced Factors interfering with rehabilitation
Nutritionally related oral problems in Elderly Factors causing recurrence of disease
patients: Alveolar Osteoporosis Wical and Swoope
Alveolar bone “Relationship between the dietary Factors of successful prevention
Participate in maintenance of body calcium combination of calcium and phosphorus Knowledge of causation
balance and the resorption of alveolar bone in Dynamics of transmission
Calcium is constantly deposited and edentulous patient”
Identification of risk factors
withdrawn from the alveolar bone to Result indicate that there is a direct cause- Availability of prophylactic or early
provide the need of other tissue and-effect relationship between low
detection
Calcium in the cancellous trabeculae is more calcium intake or calcium-phosphorus
Treatment measures
readily available thus more easily mobilize imbalance and severe ridge resorption
Organization for applying these measures
Alveolar bone acts as a reservoir of mineral Reported that ingestion of calcium and Vit D
Continuous evaluation of procedures
ions which makes it susceptible to dietary supplements reduced post
applied
osteoporosis extraction alveolar bone resorption by 36%
DNU FINALS
Level of prevention WHO approaches for primary prevention Modes of intervention for tertiary prevention
1. Primordial prevention Population (mass) strategy Disability limitation- questionable na yung
2. Primary prevention Whole population irrespective of the ability, so nililimit yung tooth
3. Secondary prevention individual risk level Rehabilitation: restoration of function (wala
4. Tertiary prevention No data na teeth dito)
Aims at socio-economic, behavioral and
Modes of intervention (preventive services) lifestyle changes Dental caries: Dental Professional Preventive
1. Health promotion High risk strategy Dentistry services
2. Specific promotion Individuals at special risk
3. Early diagnosis and treatment Primary Second Tertiary
Has data
4. Disability limitation ary
5. rehabilitation Secondary prevention
Health Specific Early Disabili Rehabilitat
- “Action which halts the progress of disease
promot promot diagnos ty ion
Primordial prevention in its incipient stage and prevent
ion ion is and limitati
- Prevention of emergence or development of complication”
prompt on
risk factor in countries or population groups - Pathogenesis phase
treatm
in which they have not yet appeared
ent
- Conduct dental education Modes of intervention for secondary prevention
early diagnosis and prompt treatment Patient Topical Comple Comple Removable
Primary prevention educati applicat te x and fixed
- “Actions taken prior to the onset of disease, Tertiary prevention on ion of exam; restorat prosthodo
which removes the possibility that a disease “All measures available to reduce or limit fluoride prompt ion ntics
will ever occur” impairments and disabilities, minimize suffering treatm dentistr
- Pre-pathogenesis phase caused by existing departures from good health ent of y
to promote patients adjustment to irremediable incipie extracti
Modes of intervention for primary prevention conditions” nt on
1. Health promotion - Late pathogenesis phase lesions
2. Specific protection
DNU FINALS