‫‪01127207099‬‬ ‫‪01015694262‬‬ ‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‪ /‬محمـــد ثـــــروت ‪ .‬د‪ /‬حســـــام زيدان ‪ .‬د‪/‬عبد الحميــــــد شعبــــــان ‪ .

‬د‪ /‬أحــمد فـــــــــرج‬

‫‪April, May EXAMXS 2023‬‬

01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Exams Updated 2023

N Q A
Tonsils
1 Secondary lymphoid organ?

Ig in asthma ? IgE
2

Ig G
3 Ig pass placenta?
Dihydrofolate
4 Methotrexate affect ?
Docetaxel
5 What cancer treatments interfere with mitosis?

Which of the following is human monoclonal Adalimumab

6
antibody?
What are preventative measures for Clostridium
Negative room pressure
7 difficile?

Anergy is a state in which the immune system is unable to

8 Anergy in immunology definition? mount a normal immune response against a specific antigen

Interleukins are a group of cytokines

9 Cytokines?
Stability
10 Cyclization in the chemical structure increase?
The Naranjo Algorithm, or Adverse Drug Reaction Probability
Scale, is a method by which to assess whether there is a causal
relationship between an identified untoward clinical event and
11 Naranjo score?
a drug using a simple questionnaire to assign probability
scores.

Need high skills

12 Disadvantage of primary resources?
Amiodarone
(Amiodarone and its active metabolite inhibit CYP2C9, which
13 Which medication increase the INR?
increases the anticoagulation effect of warfarin)

AFFINITY: REFER TO THE drug binding to receptors at any

given drug concentration
EFFICAY: the ability of an intervention a drug to
14 Affinity, Efficacy, t1/2 ! produce the desired beneficial effect
T ½: the time required for plasma concentration of a
drug to decrease by 50%

THE EQUIVALENT DOSES FROM

15 MORPHINE AND TRANSDERMAL
FENTANYL

Medication with half-life 4 hours, What is the

24hr
16 wash period?

17 Xalatan use for ? Glaucoma

-Isoflourane
-Desflurane
Which one of the follow best to be avoid before -Fentanyl
18
surgery? -Diazepam
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Pharmacy loss 117000 due to drug expiration, what 67first in, first out
19
is the best methodology?
Prontosil converted to sulfanilamide By which
20 Reductions
reaction?
A Imipramine increase absorption of aspirin
21 Imipramine and aspirin drug interaction? B Imipramine decrease absorption of aspirin
C Aspirin increase the absorption of imipramine
D Aspirin decrease the absorption of imipramine
1mg/ kg BID
22 Enoxaparin dose?
Potassium
23 Long case with peaked T wave?
Long case with tape worm? praziquantel
24
Amikacin which organ will be toxic? Kidney
25
Long case with Isotretinoin and pharmacist know
Non-maleficence
26 that the medication is category X and dispensed to
pregnant patient?
-Rapid COMT
27 Catecholamines enzyme degradation? - slow COMT

theory stating that genetic information flows only in one

28 Central dogma? direction, from DNA, to RNA, to protein, or RNA directly to
protein
Meningitis Neisseria
29 which of the following is gram negative bacteria?
30 Captopril SE? Metallic taste
Infliximab?
31 TB test
Acetylcysteine
32 Acetaminophen overdose?
Long case about viral respiratory infection + Oseltamivir
33
asthma?
Take cipro 3 hr. before
Ciprofloxacin and binder agent Counseling the pt ?
34 Administer Ciprofloxacin at least 3 hours before or 3 hours
after binders
Which drug safe in pregnancy?
35 levothyroxine
Graves diseases? Methimazole
36
Cough
37 Myrrh used for what!
Hydrolysis
38 Amphotericin B undergo which reaction?
Drug used for HTN, and it mechanism is my Prazosin
39
blocking alpha 1 receptor?
-Influenza
Vaccine in hajj? -Diphtheria
40
-Rota
-Pneumococcal
Which of the following represent QRS Ventricular depolarization
41
complex in ECG?
What is the chemical reaction of aspirin
Hydrolysis
42 tablets stored in the bathroom?
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
What resource should be used when searching for the most current clinical PubMed
43
trials on the use of novel anticoagulants for pulmonary embolism?
Drug used to treat HTN by alpha 2 blocker? Clonidine
44
Which of the following treatment Meningitis empiric treatment regimen H Ceftriaxone 2g 12 h IV
45
pylori H? 7-14 day
-Hand sanitizer
-Vitamin C
Healthy Woman afraid from respiratory infection in winter what you
-Zinc sulfate
46 recommend?
-Ask her to bring
prescription for
Antibiotics
47 Ranitidine, what is the pharmacophore?? Furan
48 Benzodiazepines antidote? Flumazenil
49 Which of the following is the bioisoster for Ropivacaine? Levobupivacaine
50 Cells involved in adaptive immunity? T cell
2.5% intravenous drug is infused at a rate of 1.5 ml/min. Which of the 2250 mg
51
amount of the drug That is infused in each hour?
The following prescription is received in a hospital pharmacy: Losartan 25 Take 1 tablet twice
52 mg. Take 1 tab BID duration: 3 weeks, Which of the following instructions daily (42 tablets)
will be on the prescription label?
How much of 5% w/v solution would be required to prepare 60 ml of 6ml
53
5mg/ml solution!
A 20 ml vial of penicillin-G potassium containing 2,000,000 units is available.
54 Each mg of the-24 drug is equivalent to 1600 units. How many milligrams of 62.50
penicillin-G potassium are there in one ml of the solution?
Pt was playing then suddenly he developed hypoxia and hypovolemia which Circulatory
55
system is affected?
Pt with HF on multiple anti failure (ACEI, BB, Spironolactone) which
56 medication if additional added will have mortality benefits? Hydralazine/isosorbide

Vit k reverse which anticoagulant? Warfarin

57
IV omeprazole
58 pt was admitted to ICU what to give for stress ulcer?
3yr old boy with symptoms consistent with otitis media what is the ABx of Amoxicillin
59 choice? 80-90mg/kg/day

Pro arrhythmic pt what to avoid? Azithromycin

60
TPMT
61 Azathioprine gene?

Codeine to morphine?
62 Oxidation

NSAID which is best for dysmenorrhea ? Mefenamic acid

63
Structure of quinolone, pointed at C7 and asked what its function? Modification at
64
C7 alter spectrum.
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Pt was having narcotic prescription from Riyadh
and went to a pharmacy in Dammam the Give the med for the remaining days (5days)
65 prescription is for pain after major surgery and it's - Don’t give
for 7 days, but the patient came after 2 days from -Call his physician
the prescription date?
66 Verapamil has drug interactions with? Diltiazem
67 Status epileptics case emergency? lorazepam IV
Nurse went to medication room and wants only
Take only one bag and return another bag to
68 one bag of the gentamicin but she found 2 bags so
the pharmacy
what she does?
Give the pt vancomycin q12h for 2 weeks
An addicted patient with MRSA and the patient -Give the pt vancomycin q24h for 2 weeks
being treated with home injections at home so we -Give the pt oral vancomycin q24h for 2 weeks
69
can discharge him? -Don't discharge him because he's addicted and
must treated in the hospital

70 lithium side effect? Polyuria

71 Medication that MASK hypoglycemia? BB
72 Propylthiouracil side effects? agranulocytosis
73 cyclophosphamide? Hemorrhagic cystitis
Don't eat, drink, or take any other medications
Ibandronate
74 (including vitamins or antacids) for at least 60
minutes.?
75 How to prevent LASA medication error? Use tall man method
76 clopidogrel gene: Cyp2c19
77 COPD patient ask about recommended vaccine? Pneumococcal & Influenza
-Budesonide ( ICS )
Female patient with asthma came to clinic, she's
- Omalizumab
well controlled on Saba her only compliant is chest
78 -No change in therapy
tightness and Wheezing I think. What can be added
-Add salbutamol to albuterol
to resolve the issue
79 Patient diagnosed with RSV what's the therapy? Supportive therapy and fluid
80 Which is used to prevent RSV? palivizumab
A patient with breast cancer had HER2 negative,
Don't use trastuzumab since HER2 is negative
now the physician asks whether to use
81 and there will be no response
trastuzumab or not . What is the appropriate
response?
Doctor prescribed 5 mg of Drug X but pharmacist
Dispensing error
82 dispensed 3 mg instead. What type of error is this?

83 How can this error be prevented? Double checking

A doctor prescribes MgSO4 to a patient with
process error
84 epilepsy, which results in the baby being admitted
to NICU. What type of error is this?
An elderly patient with diabetes has a HbA1c level
Add Liraglutide for weight loss if patient is
of 12% and is on 4 anti-diabetic medications, one
overweight. if patient is not overweight re-
of which is insulin. Patient refuses to take insulin
85 assure patient that insulin is needed due to high
due to fear of weight gain. What is the most
A1c and give advice to control weight.
appropriate intervention?
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
A woman with cancer refuses to receive chemotherapy or Explain to her the benefits and risk of
86 surgery. What is the best course of action? not receiving treatment so she can make
an informed decision.
87 What does the abbreviation OU stand for? Apply to each eye (both eyes)
What is the anti-dote of organo-phosphosphate Atropine and Pralidoxime
88
poisoning?
N-Acetylcysteine
89 What is the anti-dote in acetaminophen overdose?
90 What is the anti-dote of benzodiazepines? Flumazenil
91 How many natural amino acids in the human body? 20 natural amino acids
A patient with damaged pancreas consumes a high carb Starch (amylase produced by pancreas
92 meal. The digestion of which type of carbohydrates will catalyzed digestion of starch into
be most affected? maltose and glucose)
93 What are the components of fungal cell wall? Chitin + Glucans + Glycoproteins
94 Which of these is contains an inhaled cortisone? Pulmicort, Symbicort
95 What is a reliable source of clinical studies? Pubmed
What is the most appropriate anti-convulsant for a
96 Lamotrigine
pregnant woman?
Woman taking levothyroxine has become pregnant. What Inform prescriber to increase dose
97
is the most appropriate course of action?
A doctor has increased the dose of a patient’s anti-
Options were in % reduction in number
98 convulsant. What is the expected impact?
of seizures (don’t know answer)
99 What are the secondary lymphoid organs? Tonsils, Spleen, and Lymph nodes
100 Which surface protein is expressed by T helper (Th) cells? CD4
What type of hypersensitivity reaction is hemolytic
101 Type 2 hypersensitivity
anemia?
102 What Immunoglobulin is involved in allergic asthma? Immunoglobulin E
103 Which immunoglobulin is able to pass through placenta? Immunoglobulin G
104 Which bacteria causes Plague disease Yersinia pestis
105 Which gram-positive bacteria causes respiratory disease? Streptococcus pneumonia
Adherence of particles in a dispersion
106 What is the definition of flocculation?
form to create larger-sized particles.
Differences (fluctuations) in peak-
107 What is the definition of fluctuation (pharmacokinetic)? troughlevels within one dosing interval
at steady state (expressed as %).

Identify which drug has higher efficacy and potency from

108 a dose-response curve.

What is a small, circular, double-stranded DNA that is Plasmid

109 distinct from a cell’s chromosomal DNA known as?
 01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
pharmacist is comparing the clinical outcome of two drugs
110 with different costs. Which type of pharmacoeconomic Cost-effectiveness analysis (CEA)
analysis is this?
Definition of SNP. Single nucleotide polymorphism (change in only one nucleotide).
111
112 Which anticancer drugs target the mitosis stage Vinca Alkaloids and Texans
In which genetic mutation is Imatinib used? Philadelphia chromosome (BCR-ABL)
113
Which drug targets dihydrofolate reductase? Methotrexate
114
Three questions on identifying types of studies (e.g., retrospective cohort study,
115 clinical trial, case-controlled study,
cross-sectional study)
116 Which anti-diabetic class does sitagliptin belong to? DDP-4
What is the maximum statin dose for patient taking 40 mg
117
verapamil?
A patient who is Hajj visitor is prescribed Diazepam as
118 needed for insomnia, what is the maximum dose? 15 mg

Drug/supplement that cause heart burn? Potassium supplements

119
What requires monitoring in patient receiving
120 Potassium levels
spironolactone?
Which drug has a metallic taste? Captopril
121
122 Which drug causes sulfa allergy? Dapsone
123 What is myrrh used for? Cough/Sore throat/Congestion
What question should be asked to patient on warfarin? Do you have gum bleeding?
124
Patient comes to pharmacy with pinpoint pupils, what is the
Heroin Overdose
125 likely cause?

What are the ‘5 rights’? Right dose, right patient, right drug,
126
right time, right route
What vaccines are required for patient with Asthma/COPD? Influenza vaccine and pneumococcal
127
polysaccharide vaccine.
Can a baby receiving antiviral drug take live vaccine? No, need to wait 48hrs after stopping
128
antiviral to receive vaccine.
A company made a profit of 120,000, the operating expenses 107,000 (free cash flow = profit –
129 were 5,000, and Zakah was 8,000, what is the free cash flow? [operating expenses + tax/zakat +
other expenses])
What enhances the activity of insulin? Chromium 50. A
patient with gastric bypass, which vitamin deficiency will he B12 deficiency
130
have?

Patient with hypothyroidism, which deficiency is he likely to Iodine deficiency

131
have?
132 Which Vitamin D is used in infants Cholecalciferol (Vitamin D3)
What is the first-line treatment for patient with
Topical NSAID (gel or patch).
133 osteoarthritis where nonpharmacological measures were
ineffective!
 01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Which drug is an IV direct thrombin
134 Argatroban
inhibitor?
A female with hypothyroidism has
Alendronate (High doses of levothyroxine can cause
135 developed osteoporosis, what is the
bone resorption)
appropriate treatment?
A patient has received an organ transplant
St John’s wort
136 took herbal treatment which caused organ
failure, what is the likely herbal?
A 60 Years patient presents with meningitis,
Ceftriaxone + Vancomycin + Ampicillin
137 what is the appropriate treatment?

A neonate patient presents with meningitis, Ampicillin + Gentamicin

138
what is the appropriate treatment?
139 Which drug causes thyroid toxicity? Amiodarone
What is the treatment of thyroid toxicity?
140 Methimazole (withdraw amiodarone if possible).
141 Which drug causes pulmonary embolism? Amiodarone
What is the purpose of granulation in drug Produces larger particles (granules) from fine powder –
142 formulation? granules are free-flowing and dust-free making them
easier to compress.
What does mid arm circumference Measures arm muscle. Used as indicator of nutritional
143
measure? status in children.
144 How to check for respiratory infection? Auscultation
What is the definition of miscibility? Mixing of substances to form a homogenous solution
145 without precipitates.

66. Calculate Vd
67. Calculate Absolute bioavailability.
146 ‫ــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ‬
68. Calculate Phenytoin Correction.
69. Calculate Creatinine Clearance.
147 What type of beta-blocker is propranolol? Non-selective beta-1 and beta-2 inhibitor
What are the health complications of high blood pressure (other: gout, headache,blood
148
polycythemia (high RBC conc.)? clots).
Patient vomits two hours after taking If more than two hours, no action. If within two hours,
levonorgestrel, what is the appropriate requires repeat dose or alternative emergency
149
course of action? contraception (e.g., IUD).

What is the benefit of conjugate estrogen Prolongs half-life (acts as inactive estradiol reservoir
150
compared to non-conjugate estrogen? that is slowly converted to active estrogen)
Patient going into surgery, which medicines Depends on answer choices usually anti-coagulants,
151 should be discontinued? anti-platelets, NSAIDs, ACE inhibitors, diuretics, and
MAO inhibitors.
Patient with multiple sclerosis experiences
152 multiple relapses, what is the appropriate Natalizumab
treatment?
Infant with nasal bleed, what is the likely Vitamin K
153
deficiency?
154 What is the best base for dry skin? Ointment (used for very dry, chapped/cracked skin).
Patient still suffering from UTI even after
155 adherence to antibacterial treatment, what Change to another antibiotic
is the best course of action?
 01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Patient is non-adherent and after questioning appears to be
unable to pay for medication due to insurance running out, Cause: Economic. Solution: talk to
157
what is the cause of non-adherence and what is the best patient about benefits and risks
course of action?
Patient with Hospital-acquired pneumonia experiences Use bronchodilator (SABA) +
158
bronchospasm? SYSTEMIC Corticosteroid.
Scientists are conducting clinical trials assessing the use of Risk of extra-pyramidal symptoms
159
anti-psychotics in depression, what is the likely concerns? and metabolic problems.
What is the mode of action of mannitol? Increase osmotic pressure (osmotic
160 diuretic used to reduce intracranial
pressure)

Mannitol Structure

162 Which chemical structure can cause penicillin allergy? Beta-lactam ring
163 How is amphotericin B metabolized? Hydrolysis
164 Which of these ACE inhibitors are active? Captopril and Lisinopril
165 What type of breakdown occurs due to presence of water? Hydrolysis
What type of reaction causes the conversion of amine (NH3) Oxidative deamination (catalyzed by
166
to a carbonyl (C=O) in a catecholamine molecule? MAO enzyme)
What is the least dominant form of histamine?
167

168 What’s the property of Carboxylic group (COOH)? Acidic

169 What’s the property of Amine group (NH3)? Basic
170 What’s the property of Alkyl group (CH3)? Neutral
A patient is taking an anti-hypertensive drug, but it is still (not enough information - answer
171 not controlled, what is the best course of action? depends on age, race, and co-
morbidities).
A patient with altered kidney function is taking gentamicin Both antibiotics require renal dose
172
and ampicillin, what is required? adjustments
A patient is taking the maximum statin dose and
173 cholesterol levels are still not on target, what is the Add Ezetimibe
appropriate intervention?
A patient on insulin refuses to take insulin due to fear of Try to explain to patient the benefits
174
weight gain, what is the best course of action? of treatment to change their belief.
A grandmother brings her grandson who is presenting with
175 signs of poisoning, who should you get more information Parent/Caregiver
from?
A patient is experiencing digoxin toxicity, what treatment Digoxin Immune Fab (DigiFab) – each
176 should patient receive? 40 mg vial binds 0.5 mg digoxin (max.
20 vials).
178 What is the advantage of transdermal delivery systems? Deliver drug at a controlled rate.
179 What is the function of the excipient Aspartame? Artificial Sweetener
Can a patient who is taking Acyclovir receive the Varicella No, varicella is live vaccine thus must
180
vaccination? wait 2 days after TAKING acyclovir
A nurse was infected with Hepatitis B from infected patient Hepatitis B Vaccine + Hepatitis B
181 blood, what is the appropriate treatment? immunoglobulins
 01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Can vaccine and immunoglobulins be given together? Yes, but at different body sites
182
(different arms)
What is the best treatment for patient with a deep wound and with Td vaccination and
183 unknown Td history? immunoglobulin

184 Parasitic infection increases which cell type? Eosinophils

185 Which cell is responsible for Type I hypersensitivity reactions? Mast cells
A patient taking 850 mg of metformin twice daily but still has
186 Increase dose of metformin
uncontrolled diabetes, what is the best intervention?
187 What is the active form of Vitamin D? Calcitriol
What do you recommend for a patient that wants something to
Zinc + Vitamin C
188 help with reducing risk of respiratory tract infections due to cold
weather?
A patient who came to receive vaccination was found to have high Refer patient to doctor to
189 blood pressure in two readings, what is the best course of action? receive anti-hypertensive
treatment.
190 Mechanism of action of Fluorouracil? Thymidylate synthase inhibitor
Which anti-cancer drug works by inhibit formation of microtubules
191 by binding to tubulin? Vincristine

Which anti-cancer drug works by stabilizing microtubules thereby

192 Paclitaxel
preventing cell division during M phase?
193 What side-effect is cause by cyclophosphamide? Hemorrhagic cystitis.
194 What are the symptoms of severe malaria infection? Bleeding
What is an important information that must be asked to patient
195 Travel History
with malaria?
196 How many ATP molecules are produced from 1 glucose molecule? 38
What is the appropriate first-line treatment for patient with severe
197 Donepezil
Alzheimer disease?
198 Which antibiotic is the safest? Cephalexin
A patient has hypoalbuminemia, what effect will this have on Increase free serum
199
phenytoin levels? concentration of phenytoin
A patient has symptoms of hyperthyroidism (weight loss, insomnia,
Hyperthyroidism
200 increased sweating etc.) and labs show high T4 levels and low TSH
levels, what is the likely diagnosis?
A patient on 100 mcg of Levothyroxine becomes pregnant, what is 125 mcg (25%
201
the appropriate dose to give? increase)
A patient experiences hypoglycemia, what is the likely causative
202 Glibenclamide(Sulphonylureas)
agent?
A doctor shouted at pharmacist, but the pharmacist remained calm
203 Passive behavior
and did not respond, what type of behavior is this?
A doctor has a research question comparing the efficacy of two
204 different treatments, what research type is the most appropriate to Random Control Trials (RCTs)
answer this?
205 Which of the following is an example of primary resource? Look for RCTs in PubMed
What is the interaction of ibuprofen and aspirin? inhibition of COX-1 preventing
206
binding of aspirin.
What type of pharmacoeconomic analysis compares outcomes of Cost Benefit Analysis
207
two interventions in monetary values?
A pharmacist is comparing the cost of two generic drugs, what type Cost minimization analysis,
of pharmacoeconomic analysis is this? reduction in direct medical
208
cost.
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
A patient is taking Azathioprine OR 6-mercaptopurine
Bone marrow suppression.
209 has reduced levels of Thiopurine methyltransferase
(TPMT), what is this patient at risk of?
210 Which drug causes severe diarrhea? Irinotecan
A patient is taking Irinotecan and has UGT1A1*28 Neutropenia
211
mutation, what is this patient at risk of?
A patient is taking Phenytoin and has HLA-B 1502
212 Hypersensitivity reaction
mutation, what is this patient at risk of?
213 What is the most common gene mutation? SNP
1A child who was given codeine experiences dizziness
214
and respiratory depression, what is the likely cause?
Comparison of the drug with another medication in Phase 3
215
which phase in the clinical trial?
216 What rifampin does to carbamazepine levels? Decrease the carbamazepine levels
Long case about pt on daptomycin and captopril, Increase risk or severity of myopathy and
217
what is the interaction? rhabdomyolysis
218 Distribution of ciprofloxacin to? Adipose tissue firstly , liver and brain later
65 year old woman with DVT is on heparin 1200 units - Keep the same dose
/ hour. The nurse asks for heparin dosing - Decrease the infusion rate to 1100 /
recommendation after receiving the hematology test hour
219 this morning and aPTT 300. What is the best - Hold the infusion for 60 minutes, then
recommendation based on hospital heparin protocol? resume with 1000 units / hour
(for patient take heparin, -Hold the infusion for 60 minutes, then
you’d want your PTT results to be more like 120 to 140
seconds, and your aPTT to be 60 to 80 seconds) resume with 900 units / hour
220 Bacteria purple cocci Pairs color shaped? - Streptococcus pneumonia
Accumulation of toxic chloramphenicol metabolites
221 UDP-glucuronyl transferase
and causes gray baby syndrome due to deficiency of?
Cytomegalovirus (CMV) infection treatment in organ
222 Ganciclovir
transplant patients?
Which of the following is the benefit from adding of To extend the half-life of and improve
223
polyethylene glycol PEG in some medications? drug efficacy
Patients travel to Africa and are afraid of travel Don't eat raw meat choose drinks
224
diarrhea what is your recommendation? carefully
225 Responsible for the house worker? MOH
Long case about pt on simvastatin 80 mg form (6
-Counting on simvastatin 80
year) his LDL is good he has SLCO1B1 gene positive -
226 -Change to simvastatin 40
and no rhabdomyolysis or any other toxicity, what is
your plan?
Pt with decompensated HF which diuretic is drug of
227 Furosemide
choice?
Pt was prescribed hypnotic anxiolytic and is to be Ramelteon
228 taken before bedtime, when she wakes up she is still -Zolpidem
drowsy, what is the most likely drug? -Diazepam
- midazolam
229 Which is good for Ulcerative colitis? -Sulfasalazine
230 How do you replace vitamin D in renal failure? - calcitriol
231 Iron deficiency anemia! -hypochromic microcytic anemia
232 Vancomycin level? After the 3rd dose
Prevalence? Is the proportion of persons in a population
who have a particular disease or attribute at
233 aspecified point in time or over a specified
period of time
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Pandemic is ? an epidemic of an infectious disease that has
spread across a large region, for instance
234
multiple continents or worldwide, affecting a
substantial number of individuals.
Lovastatin high intensity dose? -40mg
235
-20m
Long case, drug of choice for anaphylaxis? -Epinephrine
236
Long case, woman 57 yr old on the maximum dose -Switch to atorvastatin
237 of rosuvastatin and not improved? -Add ezetimibe
- Add ezetimibe and cholestyramine
238 Sustained release drug if it was crushed? Toxic
Which of the following of the hypertensive -Lisinopril
therapies is preferred to be used during the acute -nicardipine
239
phase of ischemic stroke if elevated blood pressure -hydrochlorothiazide
should be treated? - metoprolol
A 23-year-old drug addict man was brought to the
Emergency Room with severe agitation and -Opioids
excitement. He was administered intravenous - Cocaine
240
diazepam, with no improvement in his condition. -Pregabalin
Which of the following is the mostly likely drug the tetrahydrocannabinol
patient was addicted on?
Patient come to pharmacy with prescription but the - tell the patient go to another pharmacy
same company not available , you have another - go to doctor to change the prescription
241 company what do! -give the same active ingredient from
different company and Counselling to the
patient
Which statin can use with grapefruit? Pravastatin (Note: Also we can use
242 rosuvastatin and Fluvastatin and Pravastatin
and Pitavastatin)
A girl come to pharmacy with eye drops she was -Discard immediately after administration
using the opened bottle for 45 days best advice? Discard after 7 days (if not have a
243 preservative)
- It is ok to use for 60 days
Discard after 28 days (if have a preservative)
244 Suspending agents are? Hydrophilic particles
Patient has uncontrolled diabetes and now has back
245 Gabapentin
pain (neuropathic pain)?
Case of a patient he came and medical team want -Voriconazole
to give a medication to cover aspergillosis, they also Fluconazole
246 want to do TDM and monitoring. Which medication -itraconazole
to give?

What is the method that used to make strength

247 Allegation
from two different strength?
Multiple sclerosis with 2 relapse per year? -Finglimod
248
-Natalizumab
Which of the following affect t
249 Volume annual sale
he ABC classifications?
Mannitol structure without name and ask about the -Osmotic diuretics or osmosis
250
mechanism of action?
01127207099 01015694262 ‫ أحــمد فـــــــــرج‬/‫ د‬. ‫عبد الحميــــــد شعبــــــان‬/‫ د‬. ‫ حســـــام زيدان‬/‫ د‬. ‫ محمـــد ثـــــروت‬/‫صيــادلـــــــــــــــــــــــه بتخدمــــــــــــــك د‬

Q A
Which of the following documents created by the
- Ethics Code
World medical Which Association is the statement
- Belmont Report
251 of ethical principles for medical research involving
-Nuremberg Zode
human subjects?
Declaration of Helsinki
A 42-year-old woman presents with complain of
epigastria burning and pain for the last 6 month 33 /
272 significant medical history but reports an allergy
A) Levofloxacin and lansoprazole for 14 days
to beta-lactam antibiotics. An office based Urea
B) Omeprazole, clarithromycin, and
Breath Test is performed to diagnose Helicobacter
amoxicillin for 10 days
252 pylori infection
C)Omeprazole, clarithromycin, and
(see lab result) Test Result
metronidazole for 14 days
Urea breath test Positive
Which of the following is the most appropriate
treatment regimen?

A patient is admitted to the hospital for the

A) Bar Coding
treatment of atrial fibrillation During hospital stay,
B) High-Risk Drug Protocol
the patient receives IV diltiazem was discharge on
C) Medication Reconciliation
oral diltiazem plus his previous antihypertensive
253 D) Computerized physician order entry
medication verapamil. Which of the following
medication error-reduction programs Would most
likely have helped to prevent this duplication of
therapy?
Which of the following distribution systems works a) Bulk ward stock
254 better for medicine requiring a higher level of B) Direct procurement
control? C) Automated dispensing
14 years-old man expressesd withdrawal symptoms
A) long acting benzodiazepines
from using benzodiazepine drug which included
B) ultra-short acting benzodiazepines
255 Irritability and aggression which of the following
C)benzodiazepines WITH ACTIVE
types of benzodiazpine is more likely associated
METABOLITES
with these symptoms
From salicylic alcohol to salicylic acid? Oxidation
256
257 Low creatinine Renal failure
Contraindicated in pregnant women? -Cyclosporine
258 -Acretin
-Amoxicillin