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Biostatisitcs and Research Methodology Syllabus Sem Viii

The document outlines a comprehensive course on Biostatistics and Research Methodology, covering essential topics such as measures of central tendency and dispersion, correlation, regression, and probability. It also discusses parametric and non-parametric tests, research design, and the analysis of experiments, including factorial design and response surface methodology. Practical components include statistical analysis using software tools like Excel, SPSS, and MINITAB.

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sanu57813555
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73 views2 pages

Biostatisitcs and Research Methodology Syllabus Sem Viii

The document outlines a comprehensive course on Biostatistics and Research Methodology, covering essential topics such as measures of central tendency and dispersion, correlation, regression, and probability. It also discusses parametric and non-parametric tests, research design, and the analysis of experiments, including factorial design and response surface methodology. Practical components include statistical analysis using software tools like Excel, SPSS, and MINITAB.

Uploaded by

sanu57813555
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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BP801T.

BIOSTATISITCS AND RESEARCH METHODOLOGY


(Theory)

Unit-I

Introduction: Statistics, Biostatistics, Frequency distribution

Measures of central tendency: Mean, Median, Mode- Pharmaceutical


examples

Measures of dispersion: Dispersion, Range, standard deviation,


Pharmaceutical problems

Correlation: Definition, Karl Pearson’s coefficient of correlation, Multiple


correlation -Pharmaceuticals examples

Unit-II

Regression: Curve fitting by the method of least squares, fitting the lines y= a +
bx and x= a + by, Multiple regression, standard error of regression
Pharmaceutical Examples

Probability:Definition of probability, Binomial distribution, Normal


distribution, Poisson’s distribution, properties - problemsSample, Population,
large sample, small sample, Null hypothesis, alternative hypothesis, sampling,
essence of sampling, types of sampling, Error-I type, Error-II type, Standard
error of mean (SEM) - Pharmaceutical examples

Parametric test: t-test(Sample, Pooled or Unpaired and Paired) , ANOVA,


(One way and Two way), Least Significance difference

Unit-III

Non Parametric tests: Wilcoxon Rank Sum Test, Mann-Whitney U test,


Kruskal-Wallis test, Friedman Test

Introduction to Research: Need for research, Need for design of Experiments,


Experiential Design Technique, plagiarism

Graphs: Histogram, Pie Chart, Cubic Graph, response surface plot, Counter
Plot graph
Designing the methodology: Sample size determination and Power of a study,
Report writing and presentation of data, Protocol, Cohorts studies,
Observational studies, Experimental studies, Designing clinical trial, various
phases.

Unit-IV

Blocking and confounding system for Two-level factorials


Regression modeling: Hypothesis testing in Simple and Multiple regression
models
Introduction to Practical components of Industrial and Clinical Trials
Problems:
Statistical Analysis Using Excel, SPSS, MINITAB®, DESIGN OF
EXPERIMENTS, R -
Online Statistical Software’s to Industrial and Clinical trial approach
Unit-V

Design and Analysis of experiments:

Factorial Design: Definition, 22, 23design. Advantage of factorial design

Response Surface methodology: Central composite design, Historical design,


Optimization Techniques

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