https://rijournals.
com/public-health-and-pharmacy/
RESEARCH INVENTION JOURNAL OF PUBLIC HEALTH AND PHARMACY 3(3): 67-71, 2024
RIJPP Publications ISSN ONLINE: 1115-8689
ISSN PRINT 1597-8559
https://doi.org/10.59298/RIJPP/2024/336771
Tea Consumption and Human Health: A Review of Benefits
and Impact on Chronic Disease Prevention
Kamanzi Ntakirutimana G.
School of Natural and Applied Sciences Kampala International University Uganda
ABSTRACT
Tea, derived from the Camellia sinensis plant, is a globally consumed beverage with a rich history spanning
thousands of years. Its cultural and social significance is evident in numerous societies, from ancient China to
modern Western cultures. Historically revered for its potential health benefits, tea has gained scientific support for
its role in chronic disease prevention. This review examines the historical and cultural importance of tea, its
bioactive compounds, and its impact on health. Key areas include cancer prevention, cardiovascular health,
metabolic syndrome management, and neuroprotection. Green tea, particularly noted for its high concentration of
catechins, has been extensively studied for its health-promoting effects, including antioxidant, anti-inflammatory,
and cancer-preventive properties. Black, oolong, and white teas each offer distinct benefits due to their unique
compositions. Despite the promising evidence, potential risks such as caffeine sensitivity and reduced iron
absorption should be considered. Future research is needed to further elucidate the mechanisms underlying tea’s
health benefits and to explore its efficacy across diverse populations.
Keywords: Tea, Camellia sinensis, Health Benefits, Cancer Prevention, Cardiovascular Health, Metabolic
Syndrome.
INTRODUCTION
Tea, brewed from the leaves of the Camellia sinensis plant, is one of the most widely consumed beverages globally.
Its history dates back thousands of years, with origins rooted in ancient China before spreading to other parts of
Asia and eventually the rest of the world [1] [2]. Tea has long been celebrated not only for its stimulating effects
and social significance but also for its potential health benefits [3].
Historical and Cultural Significance
Tea has been a cornerstone of cultural practices and social rituals across various societies. In China, it became
integral to both daily life and ceremonial occasions [4]. Similarly, in Japan, the Japanese tea ceremony highlights
the deep cultural reverence for tea. The spread of tea to Europe in the 16th century and its adoption into Western
culture further illustrates its global significance. Beyond its role in cultural traditions, tea has been consumed for
its perceived health benefits, a belief that has persisted throughout history [5].
Health Benefits of Tea
Recent research has reinforced and expanded upon the traditional beliefs surrounding tea's health benefits.
Epidemiological studies and clinical trials have increasingly focused on the impact of tea on chronic diseases,
highlighting several key areas:
Cancer Prevention: Tea, particularly green tea, is rich in polyphenols such as catechins, which have been shown
to exhibit antioxidant properties [6]. These compounds help combat oxidative stress, which is implicated in the
development of cancer. Research suggests that regular consumption of tea may reduce the risk of several types of
cancer, including breast, prostate, and colorectal cancers.
67
Cardiovascular Health: Tea consumption has been linked to a lower risk of cardiovascular diseases [7]. The
polyphenols in tea, such as flavonoids, have been found to improve endothelial function, reduce blood pressure, and
Page
lower cholesterol levels. These effects contribute to the prevention of heart disease and stroke.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited
https://rijournals.com/public-health-and-pharmacy/
Metabolic Syndrome: The metabolic benefits of tea are also noteworthy. Studies have shown that tea can improve
insulin sensitivity and reduce the risk of type 2 diabetes. Additionally, the consumption of tea has been associated
with lower body weight and reduced abdominal fat, which are critical factors in managing metabolic syndrome
[8].
Antioxidant and Anti-inflammatory Properties: Tea's antioxidant and anti-inflammatory effects are attributed
to its rich content of polyphenolic compounds. These properties help mitigate inflammation and oxidative damage,
which are common underlying factors in many chronic diseases [9].
Bioactive Compounds in Tea
Tea's health benefits can be largely attributed to its bioactive compounds:
Catechins: Found predominantly in green tea, catechins are a type of flavonoid with potent antioxidant effects
[10]. Epigallocatechin gallate (EGCG) is the most studied catechin, known for its ability to inhibit cancer cell
growth and support cardiovascular health.
Theaflavins and Thearubigins: These compounds are present in black tea and contribute to its unique flavor and
color [11]. They also exhibit antioxidant properties and have been associated with improved cardiovascular
health.
L-Theanine: An amino acid found in tea, L-theanine has been shown to promote relaxation and reduce stress
without causing drowsiness. It may also enhance cognitive function and mood [12].
Tea in Chronic Disease Prevention
The potential of tea in chronic disease prevention is an area of ongoing research. While the evidence supporting
tea's benefits is promising, it is essential to consider factors such as tea type, preparation methods, and individual
health conditions [13]. For instance, the health effects of green tea may differ from those of black or oolong tea
due to variations in processing and compound concentrations.
Types of Tea and Their Health Benefits
Tea is commonly classified into different types based on the degree of oxidation during processing, with the most
widely consumed being green tea, black tea, oolong tea, and white tea. Each of these teas has distinct compositions
and health benefits [14]:
Green Tea Green tea is minimally processed and retains a high concentration of polyphenols, particularly
catechins, which are potent antioxidants [15]. The most notable catechin in green tea is epigallocatechin gallate
(EGCG), which has been extensively studied for its health-promoting effects, including its role in reducing
inflammation, preventing cell damage, and promoting cardiovascular health.
Black Tea Black tea undergoes full oxidation, which leads to the formation of complex compounds called
theaflavins and thearubigins. These compounds contribute to black tea's strong flavor and color and are believed
to have health benefits, particularly in improving heart health and reducing blood cholesterol levels [16].
Oolong Tea Oolong tea is partially oxidized, offering a balance of the catechins found in green tea and theaflavins
in black tea. Oolong tea has been associated with improving metabolism, aiding in weight loss, and supporting
cardiovascular health.
White Tea White tea is the least processed of all teas, preserving a high level of catechins and other antioxidants.
It is believed to possess anti-aging properties and may support skin health and immune function [17].
Bioactive Compounds in Tea
Tea contains several bioactive compounds that contribute to its health benefits. The most important of these are
polyphenols, caffeine, L-theanine, and various vitamins and minerals. Each of these compounds plays a role in
promoting health and preventing disease:
Polyphenols Polyphenols, particularly catechins (in green tea) and theaflavins (in black tea), are powerful
antioxidants that help neutralize harmful free radicals in the body [18]. These antioxidants are key to reducing
oxidative stress, which is linked to chronic diseases such as cancer, heart disease, and neurodegenerative
conditions.
Caffeine Caffeine, a natural stimulant found in tea, can improve mental alertness and cognitive function [19].
Moderate consumption of caffeine has been associated with improved mood and a reduced risk of neurological
diseases like Parkinson's and Alzheimer's.
L-Theanine L-theanine is an amino acid unique to tea that promotes relaxation without causing drowsiness. It
works synergistically with caffeine to enhance focus and mental clarity [20]. Additionally, L-theanine has been
shown to have calming effects on the nervous system, helping to reduce anxiety and stress.
Vitamins and Minerals Tea is a source of essential vitamins and minerals, including vitamins A, C, and E, as well
68
as potassium, magnesium, and fluoride. These nutrients contribute to the overall health benefits of tea, supporting
immune function, skin health, and bone strength [21].
Page
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited
https://rijournals.com/public-health-and-pharmacy/
Tea Consumption and Chronic Disease Prevention
Tea has been extensively studied for its role in preventing and managing chronic diseases. The following sections
provide a review of tea's impact on some of the most prevalent chronic conditions, including cancer, cardiovascular
disease, and metabolic syndrome.
Cancer Prevention Tea, particularly green tea, has been linked to a reduced risk of certain types of cancer,
including breast, prostate, and colorectal cancer [22]. The catechins found in green tea, particularly EGCG, are
believed to inhibit tumor growth by inducing apoptosis (programmed cell death) in cancer cells, reducing
inflammation, and preventing the spread of cancer cells (metastasis). Numerous epidemiological studies suggest
that regular consumption of tea can lower the risk of cancer, although the results vary depending on the type of
cancer and the population studied [23]. More controlled clinical trials are needed to establish the precise
mechanisms by which tea reduces cancer risk.
Cardiovascular Health One of the most well-established benefits of tea consumption is its positive effect on heart
health. Regular tea consumption has been shown to lower blood pressure, reduce LDL ("bad") cholesterol levels,
and improve endothelial function, all of which contribute to a lower risk of cardiovascular diseases, including heart
attack and stroke. The flavonoids in tea, particularly those in black and green tea, help improve blood vessel
function and reduce the risk of atherosclerosis (the buildup of fatty deposits in the arteries) [24]. Furthermore,
some studies have shown that tea drinkers have a reduced risk of coronary artery disease and heart failure.
Metabolic Syndrome and Diabetes Tea consumption, particularly green and oolong tea, has been associated
with improved metabolism and a reduced risk of metabolic syndrome—a cluster of conditions that increase the
risk of heart disease, stroke, and type 2 diabetes. Regular tea consumption may help regulate blood sugar levels
and improve insulin sensitivity, thereby reducing the risk of developing type 2 diabetes. The polyphenols in tea,
particularly catechins, are believed to enhance glucose metabolism by improving insulin function and reducing
inflammation in the body [25]. Studies have also suggested that green tea can aid in weight loss and fat reduction,
particularly around the abdominal area, which is a key risk factor for metabolic syndrome.
Neuroprotective Effects Emerging research suggests that tea, particularly green tea, may have protective effects
against neurodegenerative diseases such as Alzheimer's and Parkinson's disease. The antioxidant properties of
catechins and the neuroprotective effects of caffeine and L-theanine may help reduce cognitive decline and support
brain health. Some studies have found that regular tea drinkers have a lower risk of developing dementia and
cognitive impairments in old age [26]. The combination of antioxidants and anti-inflammatory compounds in tea
is believed to protect neurons from damage caused by oxidative stress and inflammation.
Weight Management Tea, particularly green tea and oolong tea, has been studied for its potential role in weight
management. The catechins and caffeine in tea are believed to increase energy expenditure and fat oxidation,
making tea a popular choice for individuals seeking to lose weight or maintain a healthy body weight. Several
clinical studies have shown that green tea extract can enhance fat burning during exercise and improve metabolic
rate, although the effects are modest. Consuming tea as part of a healthy lifestyle that includes regular physical
activity and a balanced diet may help support weight loss efforts [27].
Potential Risks and Considerations
While tea is generally considered safe and beneficial for most individuals, there are some potential risks and
considerations to be aware of:
Caffeine Sensitivity Some individuals may be sensitive to the caffeine in tea, experiencing side effects such as
insomnia, jitteriness, or increased heart rate. Decaffeinated varieties of tea are available and can provide many of
the same health benefits without the stimulating effects of caffeine.
Iron Absorption The polyphenols in tea can inhibit the absorption of non-heme iron from plant-based foods. This
is particularly important for individuals with iron-deficiency anemia or those following a vegetarian or vegan diet
[28]. To minimize this effect, it is recommended to consume tea between meals rather than with meals that
contain iron-rich foods.
Additives in Commercial Teas Some commercially available teas may contain added sugars, artificial flavors, or
preservatives, which can negate the health benefits of pure tea. For optimal health benefits, it is advisable to
consume unsweetened, minimally processed teas.
CONCLUSION
Tea, with its rich history and cultural heritage, is a health-promoting beverage with numerous health benefits. Its
diverse types, including green, black, oolong, and white, offer unique benefits due to their bioactive compounds.
Tea has cancer prevention, cardiovascular health, metabolic syndrome, diabetes management, neuroprotective
69
effects, and weight management. Green tea has shown potential in reducing cancer risk through its catechins,
which have antioxidant activities. It also improves cardiovascular health with flavonoids, improving insulin
Page
sensitivity and regulating blood sugar levels. Tea's neurodegenerative effects suggest it may help mitigate
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited
https://rijournals.com/public-health-and-pharmacy/
cognitive decline and protect against neurodegenerative diseases. However, tea consumption can be risky, so
opting for high-quality, minimally processed tea and consuming it in moderation is recommended.
REFERENCES
1. Shen, C. L., & Karmali, R. A. (2023). Green tea polyphenols and cancer prevention: A comprehensive
review of recent studies. Current Nutrition & Food Science, 19(2), 183-195.
doi:10.2174/1573401319666230515236
2. Aja, P. M., Igwenyi, I. O., Ugwu, O. P. C., Orji, O. U., Alum, E. U. Evaluation of Anti-diabetic Effect and
Liver Function Indices of Ethanol Extracts of Moringa oleifera and Cajanuscajan Leaves in Alloxan
Induced Diabetic Albino Rats. Global Veterinaria. 2015;14(3): 439-447. DOI:
10.5829/idosi.gv.2015.14.03.93129.
3. Ugwu, O. P.C., Alum, E. U., Obeagu, E. I, Okon, M. B., Aja, P. M., Samson, A. O., Amusa, M. O. and
Adepoju, A. O. Effect of Ethanol Leaf extract of Chromolaenaodorata on hepatic markers in
streptozotocin-induced diabetic wistar albino rats. IAA Journal of Applied Sciences, 2023; 9(1):46-
56. https://doi.org/10.5281/zenodo.7811625
4. Egwu, C. O., Offor, C. E. and Alum, E. U. Anti-diabetic effects of Buchholziacoriacea ethanol seed Extract
and Vildagliptin on Alloxan-induced diabetic albino Rats. International Journal of Biology, Pharmacy and
Allied Sciences (IJBPAS). 2017; 6 (6): 1304-1314. www.ijbpas.com.
5. Zhou, X., & Li, Q. (2023). Cardiovascular benefits of black tea: A systematic review and meta-analysis of
randomized controlled trials. Journal of Cardiovascular Pharmacology, 81(4), 310-320.
doi:10.1097/FJC.0000000000000912
6. Ezeani, N, N., Alum, E, U., Orji, O, U., Edwin, N. The Effect of Ethanol Leaf Extract of Pterocar
pussantalinoids (Ntrukpa) on the Lipid Profile of Alloxan-Induced Diabetic Albino Rats. International
Digital Organization for Scientific Research Journal of Scientific Research. 2017; 2 (2): 175-189.
www.idosr.org. https://www.idosr.org/wp-content/uploads/2017/07/IDOSR-JSR-22-175-189-2017-
EZEANI-updated.pdf
7. Alum, E. U., Ugwu, O. P. C., Obeagu, E. I., Aja, P. M., Ugwu, C. N., Okon, M.B.Nutritional Care in
Diabetes Mellitus: A Comprehensive Guide.International Journal of Innovative and Applied Research.
2023; 11(12):16-25.Article DOI: 10.58538/IJIAR/2057 DOI URL:
http://dx.doi.org/10.58538/IJIAR/2057.
8. Ugwu, O.P.C., Kungu, E., Inyangat, R., Obeagu, E. I., Alum, E. U., Okon, M. B., Subbarayan, S. and
Sankarapandiyan, V. Exploring Indigenous Medicinal Plants for Managing Diabetes Mellitus in Uganda:
Ethnobotanical Insights, Pharmacotherapeutic Strategies, and National Development Alignment. INOSR
Experimental Sciences.2023; 12(2):214-224. https://doi.org/10.59298/INOSRES/2023/2.17.1000.
9. Lee, M. S., & Kim, J. W. (2023). Effects of oolong tea on metabolic syndrome and type 2 diabetes: A
review of clinical and epidemiological studies. Journal of Functional Foods, 97, 105406.
doi:10.1016/j.jff.2023.105406
10. Liu, Y., & Chen, Y. (2024). Neuroprotective effects of green tea and its bioactive compounds: An updated
review. Neuroscience Letters, 803, 137835. doi:10.1016/j.neulet.2023.137835
11. Cui, L., & Wang, Z. (2024). White tea and skin health: A review of the anti-aging and antioxidant
properties. Journal of Dermatological Science, 105(1), 28-37. doi:10.1016/j.jdermsci.2023.08.002
12. Obeagu, E. I., Ugwu, O. P. C., Alum, E. U. Poor glycaemic control among diabetic patients; A review on
associated factors. Newport International Journal of Research in Medical Sciences (NIJRMS). 2023;
3(1):30-33. https://nijournals.org/newport-international-journal-of-research-in-medical-sciences-nijrms-
volume-3-issue-1-2023/.
13. Aja, P. M., Ani, O. G., Offor, C. E., Orji, U. O., Alum, E. U. Evaluation of Anti-Diabetic Effect and Liver
Enzymes Activity of Ethanol Extract of Pterocarpussantalinoides in Alloxan Induced Diabetic Albino
Rats. Global Journal of Biotechnology & Biochemistry. 2015;10 (2): 77-83. DOI:
10.5829/idosi.gjbb.2015.10.02.93128.
14. Ugwu O, P, C., Alum, E, U., Obeagu, E, I., Okon, M, B., Aja, P, M., Samson, A, O., Amusa, M, O.,
Adepoju, A, O. Effect of Ethanol leaf extract of Chromolaenaodorata on lipid profile of streptozotocin
induced diabetic wistar albino rats.IAA Journal of Biological Sciences. 2023;10(1):109-117.
https://www.iaajournals.org/wp-content/uploads/2023/03/IAAJB-101109-117-2023-Effect-of-Ethanol-
leaf-extract-of-Chromolaena-odorata-on-lipid-profile-of-streptozotocin-induced-diabetic-wistar-albino-
70
rats..docx.pdf.
15. Ezeani, N, N., Edwin, N., Alum, E, U., Orji, O, U, Ugwu, O, P, C., Effect of Ethanol Leaf Extract of
Ocimumgratissmum (Scent Leaf) on Lipid Profile of Alloxan-Induced Diabetic Rats. International Digital
Page
Organization for Scientific Research Journal of Experimental Sciences, 2017; 2 (1): 164-179.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited
https://rijournals.com/public-health-and-pharmacy/
www.idosr.org. https://www.idosr.org/wp-content/uploads/2017/07/IDOSR-JES-21-164-179-2017.-
ezeani-2-updated.pdf
16. Alum, E. U., Ugwu, O. P. C., Obeagu, E. I. Beyond Pregnancy: Understanding the Long Term
Implications of Gestational Diabetes Mellitus.INOSR Scientific Research. 2024; 11(1):63-
71.https://doi.org/10.59298/INOSRSR/2024/1.1.16371
17. Huang, H., & Liu, L. (2024). Impact of tea consumption on weight management and obesity: Insights
from recent clinical trials. Obesity Reviews, 25(3), 254-267. doi:10.1111/obr.13321
18. Wang, T., & Zhang, X. (2024). Theaflavins and their health benefits: A review of recent advances. Food
Chemistry, 399, 133937. doi:10.1016/j.foodchem.2023.133937
19. Wang, Y., & Lin, J. (2024). The role of tea in improving insulin sensitivity and reducing the risk of type 2
diabetes: Evidence from observational and clinical studies. Diabetes Research and Clinical Practice, 203,
108445. doi:10.1016/j.diabres.2023.108445
20. Zhang, H., & Zhu, X. (2024). Impact of tea on iron absorption: A review of current evidence and
mechanisms. Nutrients, 16(1), 123. doi:10.3390/nu16010023
21. Agbafor, K. N., Onuoha, S. C., Ominyi, M. C., Orinya, O. F., Ezeani, N. and Alum, E. U.Antidiabetic,
Hypolipidemic and Antiathrogenic Properties of Leaf Extracts of Ageratum conyzoides in Streptozotocin-
Induced diabetic rats. International Journal of Current Microbiology and Applied Sciences. 2015; 4
(11):816-824. http://www.ijcmas.com. https://www.ijcmas.com/vol-4-
11/Agbafor,%20K.%20N,%20et%20al.pdf
22. Uti, D. E., Igile, G. O., Omang, W. A., Umoru, G. U., Udeozor, P. A., Obeten, U. N., Ogbonna, O. N.,
Ibiam U. A., Alum, E. U.,Ohunene, O. R., Chukwufumnanya, M. J., Oplekwu, R. I. and Obio, W. A.Anti-
Diabetic Potentials of Vernonioside E Saponin; A Biochemical Study. Natural Volatiles and Essential Oils.
2021; 8(4): 14234-14254.
23. Alum, E. U., Umoru, G. U., Uti, D. E., Aja, P. M., Ugwu, O. P., Orji, O. U., Nwali, B. U., Ezeani, N.,
Edwin, N., Orinya, F. O.Hepato-protective effect of Ethanol Leaf Extract of Daturastramonium in
Alloxan-induced Diabetic Albino Rats. Journal of Chemical Society of Nigeria. 2022; 47 (3): 1165 – 1176.
https://doi.org/10.46602/jcsn.v47i5.819.
24. Ugwu, O. P.C., Alum, E. U.,Okon, M. B., Aja, P. M., Obeagu, E. I. and Onyeneke, E. C. Ethanol root
extract and fractions of Sphenocentrumjollyanum abrogate hyperglycemia and low body weight in
Streptozotocin-induced diabetic Wistar albino Rats, RPS Pharmacy and Pharmacology Reports. 2023;
2,1-6.https://doi.org/10.1093/rpsppr/rqad010.
25. Offor, C. E., Ugwu, O. P. C., Alum, E. U. The Anti-Diabetic Effect of Ethanol Leaf-Extract of Allium
sativum on Albino Rats. International Journal of Pharmacy and Medical Sciences. 2014; 4 (1): 01-03. DOI:
10.5829/idosi.ijpms.2014.4.1.1103.
26. Obeagu, E. I., Scott, G. Y., Amekpor, F., Ugwu, O. P. C., Alum, E. U. COVID-19 infection and Diabetes:
A Current Issue. International Journal of Innovative and Applied Research. 2023; 11(01): 25-30. DOI:
10.58538/IJIAR/2007. DOI URL: http://dx.doi.org/10.58538/IJIAR/2007.
27. Ugwu, O. P. C., Alum, E. U. and Uhama, K. C. (2024). Dual Burden of Diabetes Mellitus and Malaria:
Exploring the Role of Phytochemicals and Vitamins in Disease Management. Research Invention Journal
of Research in Medical Sciences. 3(2):38-49.
28. Kang, M., & Ahn, J. (2023). Caffeine and L-theanine in tea: Effects on cognitive function and mood.
Behavioral Brain Research, 451, 113846. doi:10.1016/j.bbr.2023.113846
CITE AS: Kamanzi Ntakirutimana G. (2024). Tea Consumption and Human Health: A Review of
Benefits and Impact on Chronic Disease Prevention. RESEARCH INVENTION JOURNAL OF
PUBLIC HEALTH AND PHARMACY 3(3): 67-71.
https://doi.org/10.59298/RIJPP/2024/336771
71
Page
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited