D.pharmacy Important Question Answer PHARMACOGNOSY
D.pharmacy Important Question Answer PHARMACOGNOSY
Yoga is a way of life, which has the potential for improvement of social and
personal behaviour, improvement of physical health by encouraging better
circulation of oxygenated blood in the body, restraining sense organs, and thereby
inducing tranquillity and serenity of mind.
Naturopathy is also a way of life, with drugless treatment of diseases. The system
is based on the ancient practice of application of simple laws of nature. The
advocates of naturopathy focus on eating and living habits, adoption of
purification measures, use of hydrotherapy, baths, massage etc.
1. Alphabetical classification
The crude drugs are arranged according to the alphabetical order of their Latin
and English names.
This arrangement is employed for some reference books, dictionaries,
pharmacopoeias etc.
This are suitable for quick reference it gives no indication of inter-relationships
between drugs.
Some of pharmacopoeias and reference books which classify crude drugs
according to this system are as follows:
Indian Pharmacopoeia (IP)
British Pharmacopoeia (BP)
British Herbal Pharmacopoeia (BHP)
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United State Pharmacopoeia and
National Formulary (USP)
British Pharmaceutical Codex (BPC)
European Pharmacopoeia (Latin
title)
Encyclopedia of common natural ingredients used in drugs and cosmetics.
3. Morphological Classification
Here, the crude drugs are grouped according to the part of the plant or animal
represented into organized and unorganized drugs.
Some of the examples of crude drugs under this type of classification are as:
Parts Drugs Parts Drugs
Seeds Isabgol, Castor Fruits Fennel, Coriander
Leaves Senna, Eucalyptus Entire drugs Ephedra, Belladonna
Bark Cinchona, Cinnamon Dried latex Opium, Papain
Woods Sandalwood, Quassia Dried extracts Gelatin, Agar
Roots Rauwolfia, Jalap Dried juices Aloe
Rhizomes Turmeric, Ginger Resins Asafoetida
4. Chemical Classification
Here, the crude drugs are divided into different groups according to the chemical
nature of their most important constituent.
Since the pharmacological activity and therapeutic significance of crude drugs are
based on - the nature of their chemical constituents, it would appear that chemical
classification on crude drugs is the preferred method of study.
The crude drugs belonging to different morphological or taxonomical categories
may be brought together, provided there is some similarities in the chemical
nature of active principle.
Chemical Classification Crude drugs
Glycosides Digitalis, Senna, Liquorice
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Alkaloids Cinchona, Nux-vomica, Datura
Tannins Ashoka, Amla
Volatile oils Peppermint, Eucalyptus, Gaultheria
Lipids Castor oil, Cod liver oil, Bees wax
Carbohydrates Acacia, Agar, Pectin, Honey
Resins Jalap, Balsam of Tolu
6. Chemotaxonomic Classification
In this system of classification, the equal importance is given for taxonomical
status and chemical constituents.
The knowledge of chemotaxonomy could serve as the basis for the classification
of crude drugs.
There are certain types of chemical constituents which are characteristics of
certain classes of plants.
E.g., Tropane alkaloids generally occur in most of the members of Solanaceae.
E.g. Volatile oils occur in the membrane of Umbelliferae and Rutaceae.
3. Name the various methods of evaluation of crude drugs. Mention the organoleptic
evaluation.
Answer
Methods of Drug Evaluation
The crude drug can be identified on the basis of their-
1. Morphological or Organoleptic Evaluation
2. Histological or Microscopic Evaluation
3. Chemical Evaluation
4. Physical Evaluation
5. Biological Evaluation
4. What are alkaloids? Write about the distribution and tests of identification of
alkaloids.
Answer
Alkaloids
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The term is derived from the word ‘alkali-like’ hence, they resemble some of
the characters of naturally occurring complex amines so termed as ‘alkaloids’.
Distribution of Alkaloids
Alkaloids occur in 15% of all vascular terrestrial plants and in more than 150
different plants families.
The promising families with alkaloidal content are Apocynaceae, Berberidaceae,
Euphorbiaceae, Leguminosae, Loganiaceae, Liliaceae, Papaverceae, Rubiaceae,
Rutaceae, Solanaceae.
The major distribution of alkaloids occurs in the angiosperms. But their presence
is also detected in microorganisms, marine organisms, insects, animals and some
of the lower plants.
Examples-
1. Animal kingdom – Castoramine from Canadian Beaver.
2. Bacteria - Pyocyanine from Pseudomonas aeruginosa.
3. Lower plants –Lycopodine from lycopodium (a club moss).
5. Write the biological source, Chemical constituents and therapeutic uses of any two
of the following.
a) Aloe
Answer
Biological Source - Aloe is the dried juice collected by incision, from the leaves of
various species of Aloe. Aloe perryi Baker, Aloe vera , or Aloe barbadensis Mil and
Aloe ferox
Family - Liliaceae.
Chemical Constituents - Aloins, Barbaloin, β-barboloin and Isobarbaloin.
Therapeutic uses – Laxative and Purgative.
b) Coriander
Answer
Synonyms- Fructus coriandri, Coriander fruits, Cilantro, Chinese parsley.
Biological Source - Coriander consists of dried ripe fruits of Coriandrum sativum
Family - Umbelliferae.
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Chemical Constituents- borneol, p-cymene, camphor, geraniol, limonene, and
alpha-pinenes.
Therapeutic Uses –
o Aromatic, carminative, stimulant, alterative, antispasmodic, diaphoretic and
flavouring agent.
o It is also used as refrigerant, tonic, appetizer, diuretic, aphrodisiac, and
stomachic.
c) Clove
Answer
Synonyms - Clove buds, Clove flowers.
Biological Source - Clove consists of the dried flower buds of Eugenia
caryophyllus.
Family – Myrtaceae
Therapeutic Uses –
o It is used as aromatic stimulant, carminative, spice and antiseptic.
o The antiseptic property is due to the presence of eugenol.
Principles
Basic principles of Ayurveda involve two theory, one is Panchamahabhutas theory
and other is the Tridosha theory.
According to Ayurvedic philosophy all the living and non-living matters are made
up of five basic elements in various proportions, they are Prithvi (Earth), Jala
(Water), Teja (Fire), Vayu(air), Aakash (ether).
Even the human body is made up of these elements known collectively as the
Panchamahabhutas.
There are three basic constituents of the physiological systems known as "Doshas"
which are responsible for governing and maintaining the proper health. This
concept is known as "Tridoshic concept.“
VATA (Air) – Biological air
PITA (Bile) - Biological fire humor
KAFA (Phlegm) - Biological humor or phlegm
Principles of homeopathy
1. Concept of individualization: It stated that no two individuals in the world are
alike and the disease affecting the two individual cannot be similar.
2. Principle of similar/law of similar: It stated that the treatment of a disease by a
medicine which produces similar symptoms in the healthy individual.
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3. Principle of simplex: This principle states the use of only single, simple medicine
at one time.
4. Principle of minimum dose: It stated that lower the dose of the medication,
greater is its effectiveness.
5. Law of proving: The method used for determining which remedies were suitable
for specific disease was called proving.
6. Law of Dynamization and Dilution: Dr. Hahnemann recognized that the use of
substances that cause symptoms similar to an existing disease.
7. Law of Vital force: It stated that “Life” depends on an important and
undetectable “Vital Force”. Homeopathy medicine restores the vital energy
balance and stimulates the body’s own healing response.
5. Write the biological source and therapeutic uses of any two of the following.
a. Punarnava
Answer
Biological source: Punarnava consists of fresh as well as dried whole plant of
Boerhoavis diffusa Linn.
Family: Nyctaginaceae
Therapeutic efficacy
Punarnava possess potent antifibrinolytic, anti-inflammatory, and diuretic
properties.
b. Ashwagandha
Answer
Biological source: It consists of dried roots and stem bases of Withania somnifera.
Family: Solanaceae
Therapeutic efficacy
Ashwagandha is used for arthritis, anxiety, bipolar disorder , tumors,
tuberculosis, asthma, (leukoderma), bronchitis, menstrual problems, hiccups,
Parkinson's disease, and chronic liver disease.
c. Belladonna
Answer
Biological source: It consists of fresh or dried leaves and flowering tops of Atropa
belladonna, European Belladonna.
Family: Solanaceae
Therapeutic activity
Parasympathetic depressant (which decreases the secretions of salivary glands,
gastric secretions and check the respiration).
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Used in gastro-enteritis, hyperacidity and ulcers.
b. Podophyllum
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Answer
Biological source: Podophyllum resin is a mixture of resins obtained from the dried
rhizomes and roots of Podophyllum hexandrum Royle.
Family: Berberidaceae
Chemical constituents
The composition of resin is made up of lignans which contain at least 40% of
podophyllotoxin.
American podophyllum resin contains only 10 % of podophyllotoxin.
c. Myrrh
Answer
Biological source: It is an oleo-gum-resin obtained from the of Commiphora molmol.
Family: Burseraceae
Chemical constituents
It consists of upto 40% of resins, volatile oil (3-6%) and gum (55-60%).
It also contains β-heerabe myrrholic acid, α, β and γ commiphoric acid and few
phenolic acids.
9. Write the therapeutic and cosmetic uses of any two of the following.
a. Sandalwood Oil
Answer
Therapeutic uses
1. It is used in aromatherapy due to fragrance.
2. It is added to soaps and cosmetics.
Cosmetic uses
It is also used in Ayurvedic medicine for the treatment of common colds,
bronchitis, fever, urinary tract infections, and inflammation.
b. Aloevera gel
Answer
Therapeutic uses
Anti-tumor
Anti-inflammatory
Boosts immune system
Anti-bacterial
Cosmetic uses
1. Used in the formulation of soap and gels.
2. As an antiagening gel.
3. As a protectant in lotions.
Olive Oil
Answer
Therapeutic uses
1. Olive oil has demulcent, emollient and laxative properties.
2. It is used as a vehicle for oily parenteral preparations.
Cosmetic uses
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It is also used in the preparation of lubricants, plasters, textiles, soaps,
cosmetics and sulphonated oil.
When used externally it is an emollient and soothing.