DEPCBCS BSC ChemistrySyllabus 2024
DEPCBCS BSC ChemistrySyllabus 2024
GORAKHPUR
FOUR YEAR
B. Sc. CHEMISTRY Programme
(B.Sc. Chemistry‐ Honours and Research Programme)
Syllabus
(For the Academic Session-2024 onwards)
1
2
B.Sc. Chemistry
B.Sc. I Semester
Paper No. Paper Name No. of Credits
B.Sc. II Semester
Paper No. Paper Name No. of Credits
3
B.Sc. IV Semester
Paper No. Paper Name No. of Credits
B.Sc. V Semester
Paper No. Paper Name No. of Credits
4
B.Sc. VIII Semester (B.Sc. Chemistry Honours)
Paper No. Paper Name No. of Credits
5
SUBJECT: CHEMISTRY
(Four Year Undergraduate Course Structure)
The purpose of the undergraduate chemistry program is to provide the key knowledge
based and laboratory resources to prepare students for career as professionals in various
industries and research institutions.
6
B.Sc. I Year (CHEMISTRY)
Semester-I
(Four Year Undergraduate Course Structure)
CHE 101F: Fundamentals of Chemistry Credit 4+0
Course outcomes:
This course will provide a broad foundation in chemistry that stresses scientific reasoning and
analytical problem solving with a molecular perspective. Students will gain an understanding of
• Molecular geometries, physical and chemical properties of the molecules.
• Current bonding models for simple inorganic and organic molecules to predict structures
and important bonding parameters.
• The chapter Recapitulation of basics of organic chemistry gives the most primary and
utmost important knowledge and concepts of organic Chemistry.
• This course gives a broader theoretical picture in multiple stages in an overall chemical
reaction. It describes reactive intermediates, transition states and states of all the bonds
broken and formed.
• The chapters Chemistry of alkanes and cycloalkanes gives the clear picture of singly
bonded structure and geometry of the molecules.
Unit Topics
I Atomic Structure:
7
III Periodic properties of Atoms:
Hybridization, bond lengths and bond angles, bond energy, localized and delocalized
chemical bonding, hyperconjugation; Electronic Displacements: Inductive,
electromeric, resonance mesomeric effects and their applications
VI Mechanism of Organic Reactions:
Curved arrow notation, drawing electron movements with allows, half‐headed and
double‐headed arrows, homolytic and heterolytic bond fission, Types of reagents
electrophiles and nucleophiles, Types of organic reactions, Energy considerations.
Reactive intermediates Carbocations, carbanions, free radicals, Assigning formal
charges on intermediates and other ionic species.
VII Chemistry of Alkanes and Cycloalkanes
A) Alkanes: Classification of carbon atom in alkanes, General methods of
preparation, physical and chemical properties of alkanes, Free radical substitutions:
Halogenation ‐relative reactivity and selectivity
(B) Cycloalkanes: Nomenclature, methods of formation, chemical reactions,
Baeyer's strain theory and its limitations. Chair, Boat and Twist boat forms of
cyclohexane with energy diagrams ring strain in small rings, theory of strain less
rings. The case of cyclopropane ring, banana bonds.
Suggested Readings:
1. Lee, J.D. Concise Inorganic Chemistry, Pearson Education2010
2. Huheey, J.E., Keiter, E.A., Keiter, R. L., Medhi, O.K. Inorganic Chemistry, Principles of Structure and
Reactivity, Pearson Education 2006.
3. Shriver, D.D. & P. Atkins, Inorganic Chemistry 2nd Ed., Oxford University Press,1994.
4. Morrison,R.N.&Boyd,R.N.OrganicChemistry,DorlingKindersley(India)Pvt.Ltd.(PearsonEducation).
5. Carey, F. A., Guiliano, R. M.Organic Chemistry, Eighth edition, McGraw Hill Education,2012.
6. Clayden,J.,Greeves,N.&Warren,S.OrganicChemistry,2ndedition,OxfordUniversityPress,2012.
7. Graham Solomons, T.W., Fryhle, C. B. Organic Chemistry, John Wiley & Sons,Inc.
8. Chaube D. K. et al, A Textbook of fundamental chemistry, The Krishna Publications.
8
B.Sc. I Year (CHEMISTRY)
Semester-I Practical
(Four Year Undergraduate Course Structure)
CHE 102F: Qualitative Analysis Credit 0+2
Course outcomes:
Upon completion of this course the students will have the knowledge and skills to
understand the laboratory methods and tests related to estimation of metals ions and
estimation of acids and alkali contents in commercial products.
• Potability tests of water samples
• Estimation of metal ions in samples
• Estimation of alkali and acid contents in samples
• Estimation of inorganic salts and hydrated water in samples
Unit Topics
Dilution 0.1M to 0.001M solutions, Mole concept and preparation of molar, formal, normal
and molal solution.
Suggested Readings:
1. Mendham, J., Vogels Qauntitative Chemical Analysis, Pearson
2. Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters3‐5.
3. Harris, D.C.Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman,2016.
4. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age International Publisher,2009.
5. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Cengage Learning India
Edition
6. Chaube D. K. et al, Practical Chemistry, The Krishna Publications.
9
B.Sc. I Year (CHEMISTRY)
Semester-II
(Four Year Undergraduate Course Structure)
CHE 103F: Basic Organic Chemistry, Solid State and Chemistry Credit 4+0
of s and p-Block Elements
Course outcomes: This course will provide a broad foundation of –
Unsaturated hydrocarbons.
Basic understanding of stereochemistry of organic compounds
Chemistry of p‐block elements and noble gases.
Unit Topics
I Chemistry of Alkenes:
Methods of formation of alkenes, Elementary treatment of mechanism of (i)
addition of hydrogen, halogens, halogen acids, water and sulphuric acid and (ii)
Hydroboration, epoxidation, ozonolysis and hydroxylation.
II Chemistry of Alkynes:
Methods of formation of alkynes, Elementary treatment of mechanism of
addition reactions of carbon‐carbon triple bond‐ hydrogenation, halogenations,
hydrohalogenation and hydration reactions.
III Stereochemistry:
Concept of isomerism, Types of isomerism. (i) Optical isomerism: (a) Concept of
chirality, elements of symmetry (b) Optical isomerism of compounds containing
one (lactic acid) and two asymmetric carbons (tartaric acid). (ii) Methods of
racemization and resolution, relative and absolute configuration. (iii)
Geometrical isomerism: Maleic and fumaric acid, and methods for their
configurations. (iv) Sawhorse and Newman’s projection formula; R‐S, D‐L and E‐
Z nomenclatures. (v) Conformations of ethane and n‐butane
IV Liquid State: Intermolecular forces, structure of liquids (a qualitative description).
Structural differences between solids, liquids and gases. Liquid crystals: Difference
between liquid crystal, solid and liquid. Classification, structure of nematic and
cholesterol phases. Thermography and seven segment cell.
V General studies of s block elements : Group wise discussion of s‐block element
with respect to electronic configuration, ionisation potential, electron affinity,
electronegativity, atomic and ionic radii and their oxidation states. General trend
of their compounds.
VI Solid State:
Definition of space lattice, unit cell. Laws of crystallography (i) Law of constancy
of interfacial angles, (ii) Law of rationality of indices and iii) Symmetry elements
in crystals and law of symmetry .X‐ray diffraction by crystals. Derivation of
Bragg equation. Determination of crystal structure of NaCl and KCl.
10
VII p-Block Elements: Comparative study (including diagonal relationship) of
groups 13‐17 elements, compounds like hydrides, oxides, oxyacids and halides
of group 13‐16, hydrides of boron‐diborane and higher boranes, borazine,
borohydrides, fullerenes, carbides, fluorocarbons, silicates (structural principle),
tetrasulphur tetra nitride, basic properties of halogens, interhalogens and
polyhalides.
Chemistry of Noble Gasses: Chemical properties of the noble gases, chemistry
of xenon, structure and bonding in xenon compounds.
Suggested Readings:
1. Davis,B.G.,Fairbanks,A.J.,CarbohydrateChemistry,OxfordChemistryPrimer,OxfordUniversityPress.
2. Finar, I. L. Organic Chemistry (Volume 2), Dorling Kindersley (India) Pvt. Ltd.(PearsonEducation).
3. Nelson, D. L. & Cox, M. M. emistry7th Ed., W. H.Freeman.
4. Ball, D. W. Physical Chemistry Thomson Press, India(2007).
8. Castellan, G. W. Physical Chemistry 4th Ed. Narosa(2004).
9. R.B. Seymour & C.E. Carraher: Polymer Chemistry: An Introduction, Marcel Dekker, Inc. New
York, 1981.
10. G.Odian:PrinciplesofPolymerization,4thEd.Wiley,2004.
11. F.W.Billmeyer:TextbookofPolymerScience,2ndEd.WileyInterscience,1971.
12. P. Ghosh: Polymer Science & Technology, Tata McGraw-Hill Education,1991
11
B.Sc. I Year (CHEMISTRY)
Semester-II Practical
(Four Year Undergraduate Course Structure)
CHE 104F: Chemical Analysis Credit 0+2
Course outcomes:
This course will provide basic qualitative and quantitative experimental knowledge of
biomolecules such as carbohydrates, proteins, amino acids, nucleic acids drug molecules.
Upon successful completion of this course students may get job opportunities in food,
beverage, and pharmaceutical industries.
Unit Topics
I
Separation and identification of amino acids present in given mixture by paper
chromatography, reporting the Rf value.
Suggested Readings:
1. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson
(2012).
2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, PearsonEducation.
3. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry,Universities Press
4. Cooper, T.G. Tool of Biochemistry. Wiley‐Blackwell (1977).
5. Wilson, K. & Walker, J. Practical Biochemistry. Cambridge University Press(2009).
6. Varley, H., Gowenlock, A.H & Bell, M.: Practical Clinical Biochemistry,Heinemann,
12
B.Sc. II Year (CHEMISTRY)
Semester-III
(Four Year Undergraduate Course Structure)
CHE 201F: Chemical Dynamics, Organic & Coordination Chemistry Credit
4+0
Course Outcomes: Upon successful completion of this course students should be able to
describe chemical kinetics, kinetic theories of gases, phase equilibirium, lementary knowledge
of d‐block elements and coordination chemistry.
Unit Topics
I Chemical Kinetics: Rate of a reaction, molecularity and order of reaction,
concentration dependence of rates, mathematical characteristic of simple chemical
reactions zero order, first order, second order, pseudo order, halflife and mean life.
Determination of the order of reaction differential method, method of integration,
half‐life method and isolation method. Theories of chemical kinetics: Effect of
temperature on rate of reaction, Arrhenius equation, concept of activation energy.
Simple collision theory based on hard sphere model, transition state theory
(equilibrium hypothesis). Expression for the rate constant based on equilibrium
constant and thermodynamic aspects (no derivation).
II Phase Equilibrium: Statement and meaning of the terms‐phase, component and
degree of freedom, derivation of Gibbs phase rule, phase equilibria of one
component system water, S, He and Diamond, graphite. Phase equilibria of two
component systems Solid ‐ liquid equilibria , simple eutectic. Pb‐Ag systems.
III Aromaticity and Chemistry of Arenes:
Aromatic, Antiaromatic and non-Aromatic compounds, Nomenclature of benzene
derivatives, MO picture of benzene, Character of arenes, cyclic
carbocations/carbanions. Electrophilic aromatic substitution ‐ halogenation,
nitration, sulphonation and Friedel‐ Craft’s Alkylation with their
mechanism, Directing effects of the groups
IV Chemistry of Alcohols
Classification and nomenclature, Monohydric alcohols nomenclature, methods of
formation by reduction of Aldehydes, Ketones, Carboxylic acids and Esters, Hydrogen
bonding, Acidic nature, Differentiation among 1o, 2o and 3o alcohols, Dihydric
alcohols, Trihydric alcohols ‐ nomenclature, methods of formation, chemical
reactions of glycerol.
13
V Chemistry of Transition Elements
Chemistry of Elements of First Transition Series ‐Characteristic properties of d‐
block elements. Binary compounds (hydrides, carbides and oxides) of the elements
of the first transition series and complexes with respect to relative stability of their
oxidation states, coordination number and geometry.
Chemistry of Elements of Second and Third Transition Series- General
characteristics, comparative treatment of Zr/Hf, Nb/Ta, Mo/W in respect of ionic
radii, oxidation states, magnetic behavior, spectral properties and stereochemistry.
VI
Coordination Chemistry Coordinate bonding, double complex salts, Werner’s
theory of coordination complexes classification of ligands, ambidentate ligands,
chelates, coordination numbers, IUPAC nomenclature of coordination complexes
(up to two metal centers), Isomerism in coordination compounds, constitutional
and stereo isomerism, geometrical and optical isomerism in square planar and
octahedral complexes.
VII Theories of Coordination Chemistry
Metal‐ ligand bonding in transition metal complexes, limitations of valance bond
theory, an elementary idea of crystal field theory, crystal field splitting 7 in
octahedral, tetrahedral and square planner complexes, factors affecting the crystal‐
field parameters.
Suggested Readings:
1. Alberty,R A, Physical Chemistry,4 theditionWiley Eastern Ltd,2001.
2. Atkins,PW,the elements of physical chemistry,Oxford,1991
3. Barrow,G .M,International student Edition .McGraw Hill,McGraw-Hill,1973.
4. Cotton,F.A, Wilkinson,G and Gaus,P. L ,Basic Inorganic Chemistry,3rd Edition ,Wiley1995
5. Lee,J.D, Concise Inorganic Chemistry 4th EditionELBS,1977
6. Clayden,J.,Greeves,N.,Warren,S.,OrganicChemistry,Secondedition,OxfordUniversityPress2012.
7. Silverstein, R. M., Bassler, G. C., Morrill, T. C. Spectrometric Identification of Organic Compounds, John
Wiley and Sons, INC, Fifthedition.
8. Pavia, D. L. et al. Introduction to Spectroscopy, 5th Ed. Cengage Learning IndiaEd.
9. Willard, H.H. et al.: Instrumental Methods of Analysis, 7th Ed. Wardsworth Publishing Company, Belmont,
California, USA,1988.
10. Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York,2004.
11. Harris, D.C.: Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman,2016.
12. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age International Publisher,2009.
Suggestive digital platforms web links
1. https://www.coursera.org/courses?query=chemistry&languages=en
2. https://www.mooc-list.com/tags/physical-chemistry
3. https://www.coursera.org/learn/physical-chemistry
4. https://ocw.mit.edu/courses/chemistry/5-61-physical-chemistry-fall-2017/
5. http://heecontent.upsdc.gov.in/Home.aspx
14
B.Sc. II Year (CHEMISTRY)
Semester-III Practical
(Four Year Undergraduate Course Structure)
CHE 202F: Physical Analysis Credit
. 0+2
Course Outcomes: Upon successful completion of this course students should be able
to calibrate apparatus and prepare solutions of various concentrations, estimation of
components through volumetric analysis; to perform dilatometric experiments: one and
two component phase equilibrium experiments.
Unit Topics
I Surface Tension and Viscosity
1. Determination of surface tension of pure liquid or solution
2. Determination of viscosity of liquid pure liquid or solution
II Boiling point and Transition Temperature
1. Boiling point of common organic liquid compounds ANY FIVE: n
butylalcohol, cyclohexanol, ethyl methyl ketone, cyclohexanone,
acetylacetone, isobutyl methyl ketone, isobutyl alcohol, acetonitrile,
benzaldehyde and acetophenone. [Boiling points of the chosen organic
compounds should preferably be within 1800C]. 2.Transition
Temperature, Determination of the transition temperature of the given
substance by thermometric /dialometric method (e.g.
MnCl2.4H2O/SrBr2.2H2O)
15
B.Sc. II Year (CHEMISTRY)
Semester-IV
(Four Year Undergraduate Course Structure)
CHE 203F: Quantum Mechanics and Organic Synthesis-A Credit 4+0
Course Outcomes: Upon successful completion of this course students should be able to
describe atomic structure, elementary quantum mechanics, wave function and its
significance; Schrodinger wave equation and its applications; Molecular orbital theory, basic
ideas Criteria for forming molecular orbital from atomic orbitals, Molecular Spectroscopy,
Rotational Spectrum, vibrational Electronic Spectrum: photo chemistry and kinetics of photo
chemical reaction
Analytical chemistry plays an enormous role in our society, such as in drug manufacturing,
process control in industry, environmental monitoring, medical diagnostics, food production,
and forensic surveys. It is also of great importance in different research areas. Analytical
chemistry is a science that is directed towards creating new knowledge so that chemical
analysis can be improved to respond to increasing or new demands.
• Students will be able to explore new areas of research in both chemistry and allied fields
of science and technology.
• Students will be able to function as a member of an interdisciplinary problem‐solving
team.
• Students will be skilled in problem solving, critical thinking and analytical reasoning as
applied to scientific problems
• Students will gain an understanding of how to determine the structure of organic
molecules using IR spectroscopic technique
• To develop basic skills required for purification, solvent extraction, TLC and column
chromatography
Unit Topics
I Elementary Quantum Mechanics: Bohr’s model of H atom. de‐Broglie hypothesis.
Heisenberg uncertainty principle, Schrödinger wave equation (time dependent and
time independent) and its importance, physical interpretation of the wave function
and probability distribution curves, Radial and angular wave functions, Schrödinger
wave equation for H‐atom, separation into three equations (without derivation),
bonding wave function, concept of σ, σ*, π, π*
II Molecular Spectroscopy: Introduction: Electromagnetic radiation, regions of the
spectrum, basic features of different spectrometers, statement of the Born‐
Oppenheimer approximation, degrees of freedom
Rotational Spectrum: Diatomic molecules. Energy levels of a rigid rotor (semi‐
classical principles), selection rules, spectral intensity, distribution using
population distribution (Maxwell‐ Boltzmann distribution) determination of bond
length, qualitative description of non‐rigid rotor, isotope effect .
Vibrational Spectrum: Infrared spectrum : Energy levels of simple harmonic
oscillator, selection rules, pure vibrational spectrum, intensity, determination of
16
force constant and qualitative relation of force constant and bond energies, effect of
anharmonic motion and isotope on the spectrum, idea of vibrational frequencies of
different functional groups.
Raman spectrum: Concept of polarizability , pure rotational and pure vibrational,
Raman spectra of diatomic molecules, selection rules.
III Chemistry of Phenols : Nomenclature, structure and bonding, preparation of
phenols, physical properties and acidic character, Comparative acidic strengths of
alcohols and phenols, resonance stabilization of phenoxide ion. Reactions of
phenols electrophilic aromatic substitution, acylation and carboxylation.
IV Chemistry of Ethers and Epoxides: Nomenclature of ethers and methods of their
formation, physical properties, Chemical reactions cleavage and autoxidation,
Synthesis of epoxides, Acid and base‐catalyzed ring opening of epoxides,
V A. Volumetric Analysis
General principle of acid‐base titrations, precipitation titrations, oxidation‐reduction
titrations, iodimetry and complexometric titrations, use of EDTA for the
determination of Ca2+ and Mg2+ , Hardness of water, types of EDTA titrations and
metal ion indicators.
B. Gravimetric Analysis
Precipitation from homogenous medium, purity of precipitates, coprecipitation,
post‐precipitation, washing and ignition of precipitates, contamination and their
removal.
VI Errors and Evaluation
Definition of terms, mean and median, precision, standard deviation, relative
standard deviation, accuracy‐ absolute error, types of error in experimental data
determination (systematic), intermediate (or random) and gross, sources of errors
and the effects upon the analytical results, methods for reporting analytical data,
statistical evaluation and data ‐indeterminate errors, use of statistics
VII Separation Techniques: Solvent extraction: Classification, principle and efficiency
of the technique. Mechanism of extraction: extraction by solvation and chelation.
Technique of extraction: batch, continuous and counter current extractions.
Qualitative and quantitative aspects of solvent extraction: extraction of metal ions
from aqueous solution, extraction of organic species from the aqueous and non‐
aqueous media.
Chromatography: Classification, principle and efficiency of the technique.
Mechanism of separation: adsorption, partition & ion exchange. Development of
chromatograms: frontal, elution, and displacement methods.
17
Suggested Readings:
Alberty,R A, Physical Chemistry,4 theditionWiley Eastern Ltd,2001.
Atkins,PW,the elements of physical chemistry,Oxford,1991
Barrow,G .M,International student Edition .McGraw Hill,McGraw-Hill,1973.
Cotton,F.A, Wilkinson,G and Gaus,P. L ,Basic Inorganic Chemistry,3rd Edition ,Wiley1995
Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age International Publisher,2009.
Suggestive digital platforms web links
https://www.mooc-list.com/tags/physical-chemistry
https://www.coursera.org/learn/physical-chemistry
https://ocw.mit.edu/courses/chemistry/5-61-physical-chemistry-fall-2017/
18
B.Sc. II Year (CHEMISTRY)
Semester-IV Practical
(Four Year Undergraduate Course Structure)
CHE 204F: Separation Technique and Volumetric Analysis Credit 0+2
Course outcomes: Upon completion of this course, chemistry majors can employ critical thinking
and scientific inquiry in the performance, design, interpretation, and documentation of laboratory
experiments, at a level suitable to succeed at an entry‐level position in chemical industry or a
chemistry graduate program.
• Students will be able to explore new areas of research in both chemistry and allied fields of
science and technology.
• Students will be able to function as a member of an interdisciplinary problem‐solving team.
• Students will be skilled in problem solving, critical thinking and analytical reasoning as applied
to scientific problems
• Students will gain an understanding of how to determine the structure of organic molecules
using IR spectroscopic technique
• To develop basic skills required for purification, solvent extraction, TLC and column
chromatography
Unit Topics
Chromatographic Separations
I Paper chromatographic separation of following metal ions: i. Ni (II) and
Co (II) ii. Cu(II) and Cd(II)
19
B.Sc. III Year (CHEMISTRY)
Semester-V
(Four Year Undergraduate Course Structure)
CHE 301F: Analytical Techniques and Organic Synthesis-B Credit 4+0
Course outcomes: Biomolecules are important for the functioning of living organisms.
These molecules perform or trigger important biochemical reactions in living organisms.
When studying biomolecules, one can understand the physiological function that regulates
the proper growth and development of a human body. This course aims to introduce the
students with basic of oxygen and halogen containing functional groups, experimental
understanding of carbohydrates, amino acids, proteins, nucleic acids, and medicinal
chemistry. Upon completion of this course students may get job opportunities in food,
beverage, and pharmaceutical industries.Students will gain an understanding of which are
used as solvents and raw material for synthesis of drug and other pharmaceutically
important compounds and synthetic dyes.
Unit Topics
I UV-Visible Spectroscopy :
Origin of spectra, interaction of radiation with matter, fundamental laws of
spectroscopy and selection rules, types of electronic transitions, λmax,
chromophore and auxochromes, nBathochromic and Hypsochromic shifts, Intensity
of absorption, application of Woodward Rules for calculation of λmax for the
conjugated dienes, alicyclic, homoannualar and heteroannular;
extended conjugated systems, distinction between cis and trans isomers.
II Infrared Spectroscopy:
IR Spectroscopy: Fundamental and non‐fundamental molecular vibrations;
Hooke's law, selection rule, IR absorption positions of various functional groups;
Effect of H‐bonding, conjugation, resonance and ring size on IR absorptions;
Fingerprint region and its significance, application in functional group analysis and
and interpretation of I.R. spectra of simple organic compounds.
III Chemistry of Organic Halides
Nomenclature and classes of alkyl halides, methods of formation, chemical
reactions, Mechanisms of nucleophilic substitution reactions of alkyl halides, SN2
and SN1 reactions with energy profile diagrams; Polyhalogencompounds :
Chloroform, carbon tetrachloride; Methods of formation of aryl halides, nuclear
and side chain reactions; The addition‐elimination and the elimination‐addition
mechanisms of nucleophilic aromatic substitution reactions; Relative reactivities
of alkyl halides vs allyl, vinyl and aryl halides,
20
IV Chemistry of Carbohydrates:
Classification of carbohydrates, reducing and non‐reducing sugars, General
Properties of Glucose and Fructose, their open chain structure. Epimers,
mutarotation and anomers. Mechanism of mutarotation Determination of
configuration of Glucose (Fischer proof). Cyclic structure of glucose. Haworth
projections. Cyclic structure of fructose. Inter conversions of sugars (ascending
and descending of sugar series, conversion of aldoses to ketoses).
V Chemistry of Proteins:
Classification of amino acids, zwitter ion structure and Isoelectric point. Overview
of primary, secondary, tertiary, and quaternary structure of proteins.
Determination of primary structure of peptides, determination of N‐terminal
amino acid (by DNFB and Edman method) and C terminal amino, Synthesis of
simple peptides (upto dipeptides) by N‐protection & C‐activating groups and
Merrifield solid phase synthesis.
VI Chemistry of Nucleic Acids:
Constituents of Nucleic acids: Adenine, guanine, thymine, and Cytosine (Structure
only), Nucleosides and nucleotides (nomenclature), Synthesis of nucleic acids,
Structure of polynucleotides; Structure of DNA (Watson‐Crick model) and RNA
(types of RNA), Genetic Code, Biological roles of DNA and RNA: Replication,
Transcription and Translation
VII Introductory Medicinal Chemistry:
Drug discovery, design, and development; Basic Retrosynthetic approach. Drug
action‐receptor theory. Structure activity relationships of drug molecules, binding
role of OH group, ‐NH2 group, double bond and aromatic ring.
VIII Synthetic Dyes: Color and constitution (electronic Concept), Classification of dyes,
Chemistry and synthesis of Methyl orange, Congo red, Malachite green
Suggested Readings:
1. Morrison,R.N.&Boyd,R.N.OrganicChemistry,DorlingKindersley(India)Pvt.Ltd.(PearsonEducation).
2. Sykes, P. A guidebook to Mechanism in Organic Chemistry, Pearson Education,2003.
3. Carey, F. A., Guiliano, R. M.Organic Chemistry, Eighth edition, McGraw Hill Education,2012.
4. Loudon, G. M. Organic Chemistry, Fourth edition, Oxford University Press,2008.
5. Clayden, J., Greeves, N. &Warren, S. Organic Chemistry, 2nd edition, OxfordUniversity Press, 2012.
6. Graham Solomons, T.W., Fryhle, C. B. Organic Chemistry, John Wiley & Sons,Inc.
7. Smith, J. G. Organic Chemistry, Tata McGraw‐Hill Publishing CompanyLimited.
8. March, J. Advanced Organic Chemistry, Fourth edition, Wiley.\
21
B.Sc. III Year (CHEMISTRY)
Semester-V
(Four Year Undergraduate Course Structure)
CHE 302F: Polymer, Coordination and Inner Transition Credit 4+0
Metal Chemistry
Course outcomes: This paper provides detailed knowledge of synthesis of various class
of organic compounds and functional groups inter conversion. Organic synthesis is the
most important branch of organic chemistry which provides jobs in production & QC
departments related to chemicals, drugs, medicines, FMCG etc. industries.
Unit Topics
I Catalysis
General principles and properties of catalysts, homogenous catalysis (catalytic
steps and examples) and heterogenous catalysis (catalytic steps and examples)
and their industrial applications, Deactivation, or regeneration of catalysts.
Phase transfer catalysts, application of zeolites as catalysts. Enzyme catalysis:
Michaelis‐Menten equation, Lineweaver‐Burkplot, turn‐over
number.
II Chemistry of Lanthanides
Electronic structure, oxidation states and ionic radii and lanthanide contraction,
complex formation, occurrence and isolation, ceric ammonium sulphate and its
analyticaluses.
III Chemistry of Actinides
22
V Inorganic Spectroscopy and Magnetism
I. Electronic spectra of Transition Metal Complexes, Types of electronic
transitions, selection rules for d‐d transitions, spectroscopic ground states,
spectrochemical series, Orgel‐energy level diagram for d1 and d9 states,
discussion of the electronic spectrum of [Ti(H2O)6] 3+ and [Cu(H2O)6]2+complex
ion.
II. Magnetic properties of transition metal complexes, types of magnetic
behaviour, methods of determining magnetic susceptibility, spin‐only formula, L‐
S coupling, correlation of µ s and µ eff values, orbital contribution to magnetic
moments, application of magnetic moment data for 3d‐metal complexes. General
description of magnetic properties : Paramagnetism, diamagnetism,
ferromagnetism and magnetic susceptibility.
VI Metal Carbonyls and Nitrosyls
18‐electron rule, preparation, structure and nature of bonding in the
mononuclear and dinuclear carbonyls and nitrosyls.
VII Introduction to Polymer
Monomers, Oligomers, Polymers and their characteristics, Classification of polymers:
Natural synthetic, linear, cross linked and network; plastics, elastomers, fibers,
Homopolymers and Co-polymers, Bonding in polymers : Primary and secondary bond forces
in polymers ; cohesive energy, and decomposition of polymers.
23
B.Sc. III Year (CHEMISTRY)
Semester-V Practical
(Four Year Undergraduate Course Structure)
CHE 303F: Qualitative and Quantitative Analysis Credit 0+2
Course outcomes:
Upon completion of this course the students will have the knowledge and skills to
understand the laboratory methods and tests related to inorganic mixtures and
organic compounds.
• Separation of organic compounds from mixture
• Elemental analysis in organic compounds
• Identification of functional group in organic compounds
• Identification of organic compound
Unit Topics
I Separation and Identification of Organic Mixture
Analysis of an organic mixture containing two solid components using
water, NaHCO3, NaOH for separation and preparation of suitable derivatives
1. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J. & Smith, P.W.G., Textbook
of Practical Organic Chemistry, Prentice-Hall, 5th edition,1996.
2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry Orient-Longman,1960.
3. Harris,D.C.ExploringChemicalAnalysis,9 Ed.NewYork,W.H.Freeman,2016.
th
24
B.Sc. III Year (CHEMISTRY)
Semester-VI
(Four Year Undergraduate Course Structure)
CHE 304F: Organic Synthesis C Credit 4+0
Course outcomes: This paper provides detailed knowledge of synthesis of various class of
organic compounds and functional groups inter conversion. Organic synthesis is the most
important branch of organic chemistry which provides jobs in production & QC departments
related to chemicals, drugs, medicines, FMCG etc. industries.
The study of natural products and heterocyclic compounds offers an excellent strategy
toward identifying novel biological probes for several diseases. Historically, natural products
have played an important role in the development of pharmaceutical drugs for several
diseases including cancer and infection.
• It relates and gives an analytical aptitude for synthesizing various industrially
important compounds.
• Learn the different types of alkaloids, & terpenes etc and their chemistry and
medicinal importance.
• Explain the importance of natural compounds as lead molecules for new drug
discovery.
Unit Topics
I Reagents in Organic Synthesis
A detailed study of the following reagents in organic transformations, Oxidation
with SeO2, Jones Oxidation, PCC, PDC, NaBH4, LiAlH4, DIBAL‐H
II Organometallic Compounds- Organomagnesium compounds: the Grignard
reagents, formation, structure and chemical reactions. Organolithium
compounds: formation and chemical reactions.
III Chemistry of Aldehydes and ketones: Nomenclature and structure of the
carbonyl groups, synthesis of aldehydes and ketones with particular reference to
the synthesis of aldehydes from acid chlorides, Physical properties. Mechanism of
nucleophillic additions to carbonyl group with particular emphasis on benzoin,
aldol, Perkin and Wittig reaction Oxidation of aldehydes, Cannizzaro reaction, MPV,
Clemmensen, Wolff‐Kishner, An introduction to a,b –unsaturated aldehyde and
ketones.
IV Carboxylic acids and their Functional Derivatives
Nomenclature and classification of aliphatic and aromatic carboxylic acids.
Preparation and reactions. Acidity (effect of substituents on acidity) and salt
formation, Reactions: Mechanism of reduction, substitution in alkyl or aryl group,
stereospecific addition to maleic and fumaric acids. Preparation and reactions of
acid chlorides, acid anhydrides, amides and esters, acid and alkaline hydrolysis of
esters, trans‐esterification.
V Organic Compounds of Nitrogen- Preparation of nitroalkanes and nitroarenes,
Chemical reactions of nitroalkanes. Mechanisms of nucleophilic substitution in
25
nitroarenes and their reductions in acidic, neutral and alkaline media, Picric acid,
Separation of a mixture of primary, secondary and tertiary amines. Structural
features effecting basicity of amines. Gabriel‐ phthalimide reaction, Hofmann
bromamide reaction. Reactions of amines, electrophilic aromatic substitution in
arylamines,reactions of amines with nitrous acid.
VI Heterocyclic Chemistry
Molecular orbital picture and aromatic characteristics of pyrrole, furan, thiophene
and pyridine, Methods of synthesis and chemical reactions with particular
emphasis on the mechanism of electrophilic substitution, Mechanism of
nucleophilic substitution reaction in pyridine derivatives, Comparison of basicity of
pyridine, piperidine and pyrrole. Mechanism of electrophilc substitution reactions
of indole, quinoline and isoquinoline.
VII Rearrangements
A detailed study of the following rearrangements: Pinacol‐pinacolone, Benzil
Benzilic acid, and Fries rearrangement
Suggested Readings:
1. Morrison,R.N.&Boyd,R.N.OrganicChemistry,DorlingKindersley(India)Pvt.Ltd.(PearsonEducation).
2. Sykes, P. A guidebook to Mechanism in Organic Chemistry, Pearson Education,2003.
3. Carey, F. A., Guiliano, R. M.Organic Chemistry, Eighth edition, McGraw Hill Education,2012.
4. Loudon, G. M. Organic Chemistry, Fourth edition, Oxford University Press,2008.
5. Clayden, J., Greeves, N. &Warren, S. Organic Chemistry, 2nd edition, OxfordUniversity Press, 2012.
6. Graham Solomons, T.W., Fryhle, C. B. Organic Chemistry, John Wiley & Sons,Inc.
7. Smith, J. G. Organic Chemistry, Tata McGraw-Hill Publishing CompanyLimited.
8. March, J. Advanced Organic Chemistry, Fourth edition,Wiley.
9. Acheson, R.M. Introduction to the Chemistry ofHeterocyclic compounds, John Welly& Sons
(1976).
10. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt.Ltd. (Pearson
Education).
11. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry ofNatural
12. Products), Dorling Kindersley (India) Pvt. Ltd. (PearsonEducation).
13. Singh, J.; Ali, S.M. & Singh, J. Natural Product Chemistry, Pragati Prakashan(2010).
..
Suggested online links:
http://heecontent.upsdc.gov.in/Home.aspx
26
B.Sc. III Year (CHEMISTRY)
Semester-VI
(Four Year Undergraduate Course Structure)
CHE 305F: Chemical Energetics and Bioinorganic Credit 4+0
Chemistry
Course outcomes: Upon successful completion of this course students should be able
to describe laws of thermodynamics and its applications, phase equilibria of one and
two component system, electro chemistry ,ionic equilibrium applications of
conductivity and potentiometric measurements
Unit Topics
I Thermodynamics-1 :
First Law of Thermodynamics : Statement , definition of internal energy and
enthalpy. Heat capacity ,heat capacities at constant volume and pressure and
their relationship. Joule's law Joule‐ Thomson coefficient and inversion
temperature .
Thermochemistry: Standard state, standard enthalpy of formation Hess's
law of heat summation and its applications. Heat of reaction at constant
pressure and at constant volume . Enthalpy of neutralization . Bond
dissociation energy and its calculation from thermo‐chemical data ,
Kirchhoff's equation.
II Thermodynamics II
Second Law of Thermodynamics, Need for the law, different statements of
the law, Carnot cycle and its efficiency. Carnot theorem. Thermodynamic
scale of temperature.
Concept of Entropy, Entropy as a state function, entropy as a function of
V & T, entropy as a function of P&T, Entropy change in ideal gases and mixing
of gases. Gibbs and Helmholtz Functions Gibbs function (G) and Helmhotz
function (A) as thermodynamic quantities. A & G as criteria for
thermodynamic equilibrium and spontaneity, their advantage over
entropy change,
27
IV Colligative Properties-Ideal and non‐ideal solutions, methods of expressing
concentrations of solutions, activity and activity coefficient. Dilute solution,
colligative properties, Raoult's law, relative lowering of vapour pressure,
molecular weight determination, Osmosis, law of osmotic pressure and its
measurement, determination of molecular weight from osmotic pressure,
Elevation of boiling point and depression of freezing, Thermodynamic
derivation of relation between molecular weight and elevation in boiling point
and depression in freezing point.
V Bioinorganic Chemistry
Essential and trace elements in biological processes, metalloporphyrins with
special reference to heamoglobin and myoglobin. Biological role of alkali and
alkaline earth metal ions with special reference to Ca2+ and Mg2+. Cu
in plastocyanin and hemocyanin, Zn in carboxypeptidase and carbonic
anhydrase.
Suggested Readings:
1. Foye, W.O., Lemke, T.L. & William, D.A.: Principles of Medicinal Chemistry, 4th ed.,
B..I. Waverly Pvt. Ltd. NewDelhi.
2. Peter Atkins & Julio De Paula, Physical Chemistry 9th Ed., Oxford University Press(2010).
3. Metz, C. R. Physical Chemistry 2nd Ed., Tata
McGraw-Hill (2009). 4.
5. Ball,D.W.PhysicalChemistryThomsonPress,India(2007).
6. Castellan,G.W.PhysicalChemistry4thEdn.Narosa(2004).
7. Allen Bard ,JLarry . Faulkner R ,Fundamentals of Electrochemical methods
fundamentals and applications,newYork John ,Wiley &sons ,2001
8. H. J. Arnikar, Essentials of Nuclear Chemistry, 4th ed., New Age International, NewDelhi,
1995.
28
B.Sc. III Year (CHEMISTRY)
Semester-VI Practical
(Four Year Undergraduate Course Structure)
CHE 306F: Physico-Chemical Analysis and Organic Credit 0+2
Synthesis
Course Outcomes: Upon successful completion of this course students should be able
to quantify the product obtained through gravimetric method; determination of R
values and identification of organic compounds through paper and thin layer
chromatography laboratory techniques: perform thermo chemical reactions
Unit Topics
I Gravimetric Analysis
1. Analysis of Cu as CuSCN,
2. Analysis of Ni as Ni(dimethylgloxime)
II Estimate the following metals gravimetrically:
1. Barium as Barium sulphate
2. Zinc as Zinc Oxide
3. Iron as Iron Oxide
4. Chromium as Chromium Oxide
5. Lead as lead sulphate .
III Thermochemistry
1. To determine the solubility of benzoic acid at different temperatures and
to determine heat of the dissolution process.
2. To determine the enthalpy of neutralization of a weak acid/weak base
versus strong base/strong acid and determine the enthalpy of ionization of
the weak acid/weak base.
3. To determine the enthalpy of solution of solid calcium chloride
and calculate the lattice energy of calcium chloride from its enthalpy data
using Born‐Habercycle.
IV Preparation of organic compounds (Single Step Synthesis)
(i) p‐Bromoacetanilide
(ii) p‐Nitro acetanilide
(iii) Soap from line seed oil or coconut oil
(iv) Esterification of Benzoic Acid from Ethanol/Methanol
Suggested Readings:
1. Skkog DA, West DM Hollar, FJ, Analytical Chemistry: An Introduction 7th Edition, Sauders
college publishing, Philadelphia (2010)
2. Larry Hargis, G Analytical Chemistry: Principles and Techniques
Suggestive digital platforms web links
4. https://www.labster.com/chemistry‐virtual‐labs/
5. https://www.vlab.co.in/broad‐area‐chemical‐sciences
6. http://chemcollective.org/vlabs
29
B.Sc. Chemistry Honours and Research
Semester-VII
30
Course Outcomes:
CO 1: Symmetry elements and symmetry operations covers a wide area of research in
theoretical chemistry.
CO 2: Understanding of symmetry of normal vibrations, determination of normal modes,
mixing of internal coordinates and normal coordinate analysis of molecules develops
the basis of experimental infra red and Raman spectroscopic analysis of molecules and
their theoretical calculations via computational programmes.
Unit-2
Quantum mechanical treatment:
a. Quantum mechanical treatment of a harmonic oscillator, One dimensional
Harmonic oscillator (Classical and quantum mechanical treatments), Energy levels
of harmonic and an‐harmonic oscillators.
b. Quantum mechanical treatment of a rigid rotor
c. Rigid rotor model of a diatomic molecule, Energy levels of a rigid rotor, Rigid rotor
selection rule, A non rigid rotor.
31
Unit 3
Schrodinger equation for H atom:
Transformation of coordinates, Separation of Variables, φ,Ѳ and R equations and
theirsolutions, Spherical harmonics.
Unit 4
Many –Electron Atoms:
Antisymmetry and Slater determinant for the wave function of ground state of
multielectron atom, Self consistent field approximation ( Hartree’s Theory).
Unit 5
Approximation methods:
The variation method, Perturbation method and First order Perturbation theory.
Reference Books:
1. Quantum Chemistry by Donald A. Macquarrie
2. Molecular Quantum Mechanics by P.W. Atkins and R.S. Friedman
3. Quantum Chemistry by R. K. Prasad
4. Introductory Quantum Chemistry by A. K. Chandra
5. Quantum Chemistry by Ira N. Levine
6. Physical Chemistry by T. Engel and P. Reid
Course Outcomes:
CO 1: Students will be able to grasp fundamental concepts of operators, algebra of
operators and quantum mechanical and Schrodinger wave equations for single and
multi electron systems.
CO 2: Real analysis covers a wide area of research in computational chemistry. This
course is useful in various completive exams like CSIR‐NET, IAS, PCS.
32
CHE 403F: Main Group Elements
(4+0 Credits)
Course Objectives: The paper of main group elements is introduced to M.Sc. classes for
the study of s and p block elements of the periodic table. The core objective of this paper
is to prepare the students to understand and correlate preparation, structure, bonding
and properties of s and p block elements.
Unit-1
Stereochemistry of Bonding in Main Group Components:
dπ – pπ bonds, Bents rule, Energetics of hybridization
Unit-2
Preparation, Structure, Bonding and Technical Applications of,
a. Polyether complexes of alkali and alkaline earth metals
b. Polyphasphazenes
c. Thiazyl and its polymers, tetrasulfurdinitride.
Unit-3
a. Structure and bonding of Borane anions
b. Classification and structures of Silicates
Unit-4
Synthesis and structure of:
a. Carbides
b. Polyions of Ge, Sn, Pb, Sb, Bi and Hg
Unit-5
a. Definition and classification of organometallic compounds on the basis of
hapticity and polarity of metal‐carbon bond
b. Preparation, Properties, Structure and Applications ofalkyl and aryls of Lithium,
Beryllium, Aluminum, Mercury and Tin.
Reference Books:
1. Advance Inorganic Chemistry, 6th Edition, Cotton and Wilkinson
2. Inorganic Chemistry, 4th Edition, Principles of Structure and Reactivity by J.F.
Huheey, E.A. Keiter and R.L. Keiter, 1993
33
3. Chemistry of Elements by N.N. Greenwood and A. Ernshaw, Butterworths 1997
4. Organometallic Chemistry: A Unified Approach by R.C. Mehrotra and A.K. Singh
5. Comprehensive Coordination Chemistry Vol.3 by G. Wilkinson, R.D. Gillard, And J.A.
McCleverty, Pergamon Press 1987.
Course Outcomes:
CO 1. Students will be able to demonstrate an intuitive understanding ofcorrelation
between electronic configuration and bonding properties of elements.
CO 2. Chemistry of main group elements covers a wide area of research in inorganic
chemistry.
Unit-1
Basic principle of organic reaction mechanism:
Potential energy diagram, methods of determination of organic reaction mechanism and
their applications, kinetic isotopic effect and its importance in determination of reaction
mechanism.
Unit-2
Substitution Reactions:
a. Aromatic electrophilic substitution: General view, energy profile diagram,
arenium ion mechanism (ArSE ) of different aromatic electrophilic substitution
reactions, ipso‐substitution and ortho/ para ratio.
b. Aromatic nucleophilic substitution: (ArSN) Addition‐ elimination and
elimination‐ addition (benzyne) mechanisms,
c. Aliphatic nucleophilic substitution: Mechanism and stereochemistry of SN1, SN2,
SN’ and SNi reactions, role of substrate’s. Nuleophilic substitution at bridged head
carbon atom.
34
d. Neighouring group participation (NPG): Evidence for NGP,participation of
sigma., Pi‐ bonds, halogen, N‐atoms and phenyl ring.
Unit-3
Elimination reaction:
E1, E2 and E1cb mechanisms, orientation ( Saytzef’s and Hoffmann eliminations),
pyrolytic (syn ) elimination, stereochemistry of E2 reaction, factors affecting E1, E2 and
E1cb reactions, Competition between substitution and elimination reactions.
Unit-4
C=C Bond Addition :
Mechanism and stereochemistry of addition of halogen and halogen acids to alkenes,1,2‐
hydroxylation, oxymercuration‐demercuration, Corey epoxidation and cyclopropanation,
Simmon‐Smith cyclopropanation and Sharpless asymmetric epoxidation ( SAE ).
Unit-5
C-Hetero multiple Bond addition:
Mechanism of hydrolysis of ester and amide. Crame’s rule. Condensationreaction
involving Cannizzaro, Claisenand Knovenagel.
Reference Books:
1. Advanced Organic Chemistry Part. A &B By F. A. Carey and R. J. Sundberg, Plenum Publisher ,
New York, 2007.
2. Advanced Organic Chemistry By J. March, 2007.
3. Organic chemistry By J. Clayden, N. Greeves, S. Warren and P. Wothers, Oxford
University Press , New York, 2001.
35
Semester-VII (Practical)
CHE 405F: Surface Chemistry, purification and identification of materials
(0+4 Credits)
Physical Chemistry exercises:
36
B.Sc. Chemistry Honours
Semester-VIII
CHE 406F: Analytical Chemistry
(4+0 Credits)
Course Objectives:
1. To study concepts and theories behind basic methods and techniques used in
analytical chemistry. This theory can be used to solve many rigorous problems of
universe.
2. To prepare the students for further research in analytical methods of chemistry.
Unit-1
Electroanalytical Techniques:
a. Conductometric: Discussion of the nature of the curves of acid‐base (including
mixtures of acids), precipitation and complexometric titrations
b. Potentiometric: Different types of electrodes, discussion of the nature of the curves
for oxidation‐reduction and acid‐base titrations, comparision with the
conductometric method
c. Voltammetry: Cyclic voltammetry
d. Polarography: Dropping mercury electrode and its advantages, polarographically
active species, concept of residual, diffusion and limiting current of half wave
potential, Ilkovic equation and factors affecting diffusion current
Unit-2
Thermoanalytical Methods:
a. Thermogravimetry: Apparatus, factors affecting TG, Interpretation of TG curves of
CaC2O4.H2O and MgC2O4.2H2O
b. Differential Thermal Analysis and Differential Scanning Calorimetry:
Apparatus, factors affecting DTA and DSC curves with special reference to heating
rate, particle size and packing, measurement of heat of transition, heat of reaction
and heat of dehydration of salts and metal hydrates.
37
Unit-3
Radiochemical Methods
a. Isotope method
b. Inverse isotopic dilution
c. Neutron activation technique
Unit-4
Chromatographic Method:
a. Gas Chromatography: GLC and GSC
b. HPLC
Unit-5
Spectral Methods:
a. Nephelometry
b. Turbidimetry
c. Flame Photometry
Reference Books:
1. Fundamentals of Analytical Chemistry: D.A. Skoog, D.M. West and F.J. Holler, 1992, 6e
2. Quantitative Inorganic Analysis, A.I. Vogel, 2012, 7e
3. Instrumental Methods of Chemical Analysis: B.K. Sharma, 2011
4. Instrumental Methods of Chemical Analysis: H. Kaur, 2016, 12 e
5. Analytical Chemistry, Gary D. Christian, 2007, 6e
6. Instrumental Methods of Analysis: H.H. Willard, L.L. Merrit, Jr. J.A. Dean, 1974, 5e
Course Outcomes:
CO 1. Understand the basic of this course and think & develop new ideas and concepts in
analytical chemistry
38
CHE 407F: Thermodynamics and Electrochemistry
(4+0 Credits)
Course Objectives: The main objective of the course is to provide fundamentalconcepts
of thermodynamics effects and relationships. The course is to give knowledge of
comprehensive and rigorous treatment of classical thermodynamics, thermodynamics
relations. Explain the concept of partial molar properties fugacity and activity. The
course is designed to give an insight of phenomena of electrolytic conductance,
reactions in solutions, basic principles of electrical phenomena are important for
interfaces and electrode processes.
Unit 1
a. Some important thermodynamic effects and relationships :
The Joule Thomson’s effect, The Gibbs Helmoltz equation and its application, The
ClausiusClapeyron equation, The Maxwell’s relation.
b. Partial molar Properties
Fugacity, variation of fugacity with temperature and pressure, Activity and the
activity coefficient.
Unit 2
The Third law Thermodynamics:
The third law, Nernst heat theorem, application of third law, The residual entropy.
Unit 3
Electrolytic Conductance of strong electrolytes:
Debye‐Falkenhagen effects, Wein effects the ionic association, effect of ionic strength on
rate of ionic reactions.
Unit 4
Electrical phenomena at interface:
The electrical double layer, electrokinetic phenomena, quantitative treatment of electro
osmosis, Electrophoresis and streaming potential.
39
Unit 5
Electrode processes:
Dissolution and deposition potential, decomposition potential and its determination,
Concentration Polarization and over voltage(hydrogen overvoltage and oxygen
overvoltage), The Limiting current density.
Reference Books:
1. Thermodynamics for Chemists by S.Glasstone.
2. An Introduction of Chemical Thermodynamics by R.P.Rastogi and R.R.Mishra.
3. Thermodynamics by K.S.Pitzer
4. Electrochemistry by S.Glasstone
5. Electrochemistry by Potter
6. Modern Electrochemistry by Bockris Reddy VoL I&II
7. Comprehensive Physical Chemistry byN.B. Singh,S.S. Das and N.S. Gajbhiye, New Age
International Publishers.
Course Outcomes:
CO 1. To understand various thermodynamic relationship, the concept of free energy
and partial molar quantities, activity and activity coefficients and determination.
CO 2. To understand the phenomena of electrolytic conductance. Reactions in solutions.
CO 3. To understand electrical phenomena at interfaces and electrode processes.
CO 4. To understand application of electrochemistry in electrolytic processes.
40
CHE 408F: Transition Elements
(4+0 Credits)
Course Objectives:
1. Train students to grasp fundamental chemistry of transition metal elements‐
group of element whose atom has a partially filled d sub‐shell.
2. To understand principles of structure, stereochemistry, kinetics and mechanism
of transition metal elements.
3. To prepare the students for further research in transition metal chemistry.
Unit-1
Structures of 2 to 8 Coordinate Metal Complexes:
Cation‐anion ratio in various polyhedral, Hybrid orbitals and preferred conditions of
formation of the complexes of following geometries :
C.N.2 ‐ Linear
C.N.3 ‐ Trigonal planar, Trigonal pyramidal
C.N.4 ‐ Tetrahedral, Square planar
C.N.5 ‐ Trigonal bipyramidal, Square pyramidal, pentagonal.
C.N.6 ‐ Octahedral, Trigonal prism
C.N.7 ‐ Pentagonal bipyramidal, Capped octahedral, Capped trigonal prism.
C.N.8 ‐ Cubic, Tetragonal antiprismatic, Dodecahedral, Hexagonal bipyramidal, and
Bicapped trigonal prism,
Stereochemical non‐rigidity in four to eight coordinate Complexes.
Unit-2
Stereoisomerism in six coordinate octahedral complexes (Ma3bcd, Ma2bcde, Mabcdef
and complexes containing bi‐and ter‐ dentate ligands, Intermolecular and
intramolecular rearrangements ( Bailar and Ray Dutta twist only), mechanism of
racemisation in tris (chelate) octahedral complexes, Methods of resolution of optical
isomers.
Unit-3
Kinetics and mechanism of substitution reactions in octahedral Co (III) and square
planar Pt (II) complexes.
41
Unit-4
Mechanism of one electron transfer reactions (inner and outer sphere mechanisms),
Factors affecting the rates of direct electron transfer reactions and the Marcus equation,
Two electron transfer reactions.
Unit-5
Metal Ligand Equilibria in Solution:
Step wise and overall formation constants and their relations, Factors affecting the
stability of metal complexes with reference to the nature of metal ions and ligands,
determination of stability constants by pH‐metric and spectroscopic methods.
Books Recommended:
1. Inorganic Chemistry, 4th Edition, Principles of Structure and Relativity by J.E. Huheey, E.A.
Keiter and R.L. Keiter, 1993
2. Chemistry of Elements by N.N. Greenwood and A. Ernshaw, Butterworths, 1997
3. Mechanism of Inorganic Reactions; A Study Of Metal Complexes in Solution by F. Bosolo and
R.G. Pearson
4. Ligand Field Theory And Its Application by B.N. Figgis and M.A. Hitchman, Wiley, NewYork,
2000.
Course Outcomes: After studying this course the student will be able to,
CO 1. Understand the basic of transition metal chemistry and think & develop new ideas
in this field.
CO 2. Know geometries of 2 to 8 coordinate metal complexes, streoisomerism, kinetics
and mechanism of substitution reactions in octahedral and square planar complexes.
CO 3. Understand mechanism of electron transfer reactions and stability of transition
metal complexes.
CO 4. Develop new ideas for further research in the field of coordination chemistry.
42
structures, organic structural determination, semi‐synthetic to total synthetic pathways
of organic structures etc.
Unit- 1
Acetogenins : Classification, general method of structure determination of,
a. Flavones‐ Chrysin
b. Flavonols–quercetin
c. Anthocyanins‐ Cyanin
d. Anthocyanidins‐ cyanidin chlorides
Unit-2
Terpenoids : Introduction, isolation and general methods of determining structure of,
a. Monoterpenoids
i. Acyclic monoterpenoids: Citral and geraniol
ii. Monocyclic monoterpenoids : ‐Terpineol
Unit-3
Alkaloids: Introduction and general methods of determining structure of,
i. Hemlock alkaloid‐ Coniine
ii. Pyrrolidine‐Pyridine alkaloid‐ Nicotine
iii. Chincona alkaloids ‐Quinine
iv. Opium alkaloids : Papaverine and Morphine
v. Rauwolfia alkaloids
Unit-4
Carbohydrates: Structure and functions of,
Disaccarides‐ Lactose, Sucrose
Unit-5
Biosynthesis of natural products:
i. The acetate hypothesis, Isoprene rule, mevalonic acid from acetylco‐enzyme – A,
biogenesis of terpenoids
ii. Shikimic acid pathway of biogenesis of aromatic ring
iii. General biogenesis of alkaloids
Reference Books:
1. Organic Chemistry, I.L. Finar Vol. I and II, 2000
43
2. Natural Products, S.M. Chawla, 2018
3. Biochemistry‐Lehninger, 2000
4. Biochemistry by L. Stryer, 1995
Course Outcomes: After studying this course the student will be able to,
CO 1. Understand basics of different classes of natural products‐ Acetogenins,
Terpenoids, Alkaloids and Carbohydrates and their general structural determination.
CO 2. Know about acetate hypothesis, isoprene rule, biogenesis of – Terpenoid, aromatic
ring (Shikimic acid pathway) and alkaloid.
CO 3. develop ideas for further research total organic synthesis.
Organic:
Analysis of binary organic mixture (Liquid‐Liquid, Liquid‐Solid, Solid‐Solid)
44
B.Sc. Chemistry Research
Semester-VIII
Unit-2
Thermoanalytical Methods:
a. Thermogravimetry: Apparatus, factors affecting TG, Interpretation of TG curves of
CaC2O4.H2O and MgC2O4.2H2O
b. Differential Thermal Analysis and Differential Scanning Calorimetry:
Apparatus, factors affecting DTA and DSC curves with special reference to heating
rate, particle size and packing, measurement of heat of transition, heat of reaction
and heat of dehydration of salts and metal hydrates.
Unit-3
Radiochemical Methods
a. Isotope method
b. Inverse isotopic dilution
45
c. Neutron activation technique
Unit-4
Chromatographic Method:
a. Gas Chromatography: GLC and GSC
b. HPLC
Unit-5
Spectral Methods:
a. Nephelometry
b. Turbidimetry
c. Flame Photometry
Reference Books:
7. Fundamentals of Analytical Chemistry: D.A. Skoog, D.M. West and F.J. Holler, 1992, 6e
8. Quantitative Inorganic Analysis, A.I. Vogel, 2012, 7e
9. Instrumental Methods of Chemical Analysis: B.K. Sharma, 2011
10. Instrumental Methods of Chemical Analysis: H. Kaur, 2016, 12 e
11. Analytical Chemistry, Gary D. Christian, 2007, 6e
12. Instrumental Methods of Analysis: H.H. Willard, L.L. Merrit, Jr. J.A. Dean, 1974, 5e
Course Outcomes:
CO 1. Understand the basic of this course and think & develop new ideas and concepts in
analytical chemistry
Unit I
Sampling methods and lab practices
Methods of sampling solids, liquids and gases, good lab practices, lab safety, waste disposal and
managements, methods of storing chemicals, solvents and glassware.
Unit II
Introduction to basic non-instrumental laboratory techniques
46
Sample preparation, solution preparation, gravimetric analysis and volumetric techniques such
as complexometric titration and types of EDTA titration.
Unit III
Introduction to basic instrumental laboratory techniques
Use and maintenance of analytical balance, potentiometer, pH meters, conductivity meters,
mechanical stirrers, melting point apparatus, water heaters, water deionisers, magnetic stirrers
and hot plates etc.
Unit IV
Fundamental aspects of various spectroscopy techniques
Introduction to UV‐Visible, IR, NMR, EPR spectroscopies and Magnetic Measurements.
Unit V
Fundamental aspects of some analytical techniques
Basic principle, instrumentation and applications of Chromatographic methods, Atomic
absorption spectroscopy and Flame photometry.
Reference Books:
1. Willard, H.H., Merritt, L.L., Dean, J.A., Instrumental methods of analysis, CBS Publishers
and distributers, Shahdara, Delhi, 1986.
2. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J., Smith, P.W.G. Vogel’s practical
organic chemistry, Pearson Education India, 1996.
3. Vogel, A.I., Elementary practical organic chemistry: Small scale preparations Part 1,
Pearson Education India, 2010.
4. Silverstein, R. M., Webster, F.X., Spectrometric identification of organic compounds, John
Wiley and Sons, 1997.
.
*****
47
AECC 01F: ACADEMIC WRITING
(Semester I)
Unit 1
NTRODUCTION TO THE PROCESS OF WRITING
Persuasive, analytical.
Unit 2
TOOLS OF WRITING
Unit 3
WRITING ESSAYS
Unit 4
Style of writing Citation Style‐ types of citation styles ‐ for books, book chapters andonline
articles, Understanding of Plagiarism and how to avoid Plagiarism
Texbook(s):
1. L Lennie Irvin, What is Academic Writing,
2. John J Ruszkiewicz and Jay Dolmage, How to Write Anything,
3. Gordon Taylor, A Students’ Writing Guide: How to Plan and Write Successful Essays,
4. John J Ruszkiewicz and Jay Dolmage, MLA & APA documentation and Format from
How to Write Anything ,
5. F.M. Connel, A Textbook for the Study of Poetry, 2013
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AECC 02F Personality Development and Leadership
(Semester II)
Unit I
Personality: Concept and Definition, Determinants of personality, Personality traits,
Personality characteristics in organizations: Self‐evaluation, Self‐efficacy, Self‐esteem, Self‐
monitoring: Positive and negative Impact. Organizational Context of Leadership and
Personality.
Unit II
Leadership: Definition Importance of Leadership and Management, Leader vs Manager,
Essential qualities of an effective leader
Unit III
Types of Leaders: Traditional, Transactional, Transformational, Inspirational and
servant leadership, Issues in leadership: Emotional Intelligence and leadership, Trust as
a factor, Gender and Leadership.
Unit IV
Theories of Leadership: Trait theory, Behavioral theories, Contingency theory .
Book Reference:
1. Organisational Behaviour ,M.Parikh and R.Gupta , TataMcGraw Hill Education Private
Limited
2. Organisational Behavior, D. Nelson, J.C Quick and P. Khandelwal, Cengage Publication.
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AECC 03F Industrial Waste Management
(Semester III)
Unit 1
Classification, sources and composition of solid, liquid and gaseous wastes, hazardous
Unit 2
Unit 3
Unit 4
50
AECC 04F Occupational Health Management
(Semester IV)
Unit I
Unit II Concept of personal protective equipments: types and uses, Threshold limit
Unit III
Unit IV
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SECC 01F: Laboratory tools and techniques
Semester I
handling and storage, Equipment Safety and proper handling, Calibration of glasswares,
Ferric chloride solution, Ferrous sulphate solution, Iodine solution, Fehling solution,
practices.
Recommended books:
1. Vogels Text book of Quantitative Chemical Analysis, 5th edition
2. Vogels Text book of macro and semimicro qualitative inorganic analysis. G. Svela, 5th
edition
3. Chemical reagent manual prepared by Chemistry department, SGTB Khalsa college
under DBT’s Star College Scheme, University of Delhi (Available online)
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SECC 02F: Industrial Processes
Semester II
and production. Visit of some industries and corporate offices situated near by
Gorakhpur area.
emphasizing on ideal process chemical route, its efficiency, greener way to synthesize
Principle and practices related to Quality control and Assurance in industries like
Recommended books:
1. E. Stocchi: Industrial Chemistry, Vol‐1, Ellis Horwood Ltd. UK.
2. Sharma, B.K. & Gaur H. Industrial Chemistry, Goel Publishing House, Meerut (1996).
3. Handbook of analysis and quality control for fruits and vegetable products, S.
Ranhganna, Tata McGraw‐Hill Education, 1986‐Food.
4. Srilaxmi, Food Science, Edition: 3rd (2004). 7.Lillian Hoagland Meyer, Food Chemistry
(2008).
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SECC 03F: Environmental studies and Computer application
Semester III
pollution, preventive actions of global warming and green house effects, radiation
communication and internet basic of computer network, basic of electronic mail and
Recommended books:
1. Environmental pollution, download. Nos.org/333courseE/10.pdf
2. Fundamental concepts of applied chemistry J.C. Ghosh, S. Chand and CO, LTD, New
Delhi.
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