ACKNOWLEDGEMENT
In this accomplishment of this project
successfully many people had bestowed upon
me their blessings and their heart pledged
support,I am utilizing this to thank all the
people who have been concerned with this
project.Primarily I would thank god for being
able to complete this project with success,then
I would like to thanks our Principal Dr.Senthil
Kumar Sir and my Chemistry Sir Mr.Kathirvel
whose valuable guidance has been the one
that helped me patched this project and make
it full proof success.Their suggestions and
instructions has served as a major contributor
towards the completion of this file.Then I would
finally like to thank my parents and friends who
have helped me with their valuable
suggestions and guidance have been very
useful in various phase of the completion of
this project.
CONTENTS
Abstract
Estrification
Introduction
Theorys
Calculations
Procedures
Observstions
Conclusion
REDUCTION OF ALCOHOL FROM
OUR BODY THROUGH
ESTERIFICATION
ABSTRACT
This report is pertaining to a method to remove alcohol
from stomach before significant amount enters blood. The
objective is to determine if organic acids can react
efficiently with alcohol in an esterification reaction to
possibly eliminate it from human body[1]. The experiment
are carried out with a view to create some sort of
medication where the quantity of acetic acid would be
consumable.Intention behind this project is not to
motivate alcohol consumption but to provide an easy
remedy for critical conditions.
Keywords :
alcohol, esterification, medication, organic acids.
ESTRIFICATION REACTION
Alcohols can combine with many kinds of acids to form esters.
When no type of acid is specified, the word ester is assumed to
mean a carboxylic ester, the ester of an alcohol and a carboxylic
acid. The reaction, called Fischer esterification, is characterized
by the combining of an alcohol and an acid (with acid catalysis) to
yield an ester plus water.
Under appropriate conditions, inorganic acids also react with alcohols to
form esters. To form these esters, a wide variety of specialized reagents
and conditions can be used.
INTRODUCTION
All across the globe consumption of alcohol is increasing day by
day or rather has become a trend. Youngsters have fallen for this
and start consuming alcohol at an early age. Alcohol consumption
gives rise to serious health disorders. It damages liver causing
liver cirrhosis, shows a range short term and long term disorders
on brain and central nervous system and also affects the
reproductive organs. To tackle these problems and to contribute to
a healthy living, we came up with this idea of reducing alcohol to
ester using esterification reaction.
THEORY
REACTIONS:
1. Actual esterification reaction
C2H5OH + CH3COOH CH3COOC2H5 + H20
(Ethyl alcohol + Acetic acid Ethyl acetate + Water)
2. Pre- esterification reaction
2CH3COOH + Ca(OH)2 CH3COO-Ca-OOCCH3 + 2H2O
(Acetic Acid + Calcium Acetate Hydroxide + Water)
3.Modified esterification reaction
2C2H5OH + CH3COO-Ca-OOCCH3+ 2CH3COOC2H5+ Ca(OH)2
(Ethanol + Calcium Acetate + Ethyl Acetate+ Calcium
Hydroxide)
CALCULATIONS
Some necessary calculations to obtain right pH of solution i.e. in
the range of 3-4 are as follows
1.100 ml of vinegar contains approximately 0.067-0.087 moles of
acetic acid depending upon manufacturer.
2. According to FDA, recommended consumption of calcium for
an adult is 1.3g per day.[2]
3.Now, 100ml = 0.067 moles of acetic acid
1000ml = 0.6 moles of acetic acid
4.Approximately the concentration of vinegar should
be 0.03M using,
M1 V1 = M2 V2
we obtain the quantity of vinegar as, (1000x0.03)/0.6 = 44 ml
5. Permissable value of Ca(OH)2 0.02 moles
the amount of Ca(OH)2 required is 0.24 x 74 , where the
molecular weight of Ca(OH)2 is 74 = 1.48g
PROCEDURE
Preparation of Solution:
1. Take 44ml of vinegar in a beaker.
2. Measure 1.48g of calcium hydroxide using digital weighing
machine.
3. Add the measured calcium hydroxide to the beaker
containing vinegar and stir well.
4. With the help of pH paper or pH indicator solution,
measure the pH of solution ( we had used pH meter for
accuracy )
5. Obtained pH should be in the range of 3-4.
Titration against Potassium Permanganate:
1. Take 10 ml of this solution and add 10 ml alcohol to it.
2. Fill the burette with 2% KMnO4.
3. Perform the titration till brown color is obtained.
OBSERVATIONS
1. Alcohol reacts with acetate ions present in the
solution to form ester , ethyl acetate.
2. It is indicated by citric flavor aroma of ester
instead of pungent smell of acetic acid.
3. Observations from titration suggest complete
reduction of alcohol to ester because:
i. Potassium permanganate (KMnO4) which is
purple coloured acts as indicator and end point
achieved is purple- brown colour.
ii. Formation of MnO2- ions gives the brown colour
and suggests reduction of alcohol.
CONCLUSION
Alcohol can be harmful to human body as it can cause
heavy damage to liver like liver cirrhosis. Short term
effects on brain include dizziness, drowsiness, loss of
concentration, and mood swings. Long term effects
include memory loss, strokes and concussions.
Reproductive organs are also damaged due to
consumption of alcohol. It can result in infertility or
physical deformities and mental retardation in case of
fetus.
Esters having negligible effect on our health proves to be a
better alternative than alcohol in our body.
Using edible colours and artificial flavors it can be used in
pharmaceutical and drug industry.
Usually our liver takes 10-12 hours to reduce alcohol but
this might prove to be a faster solution
Bibliography
