1

DOPA-01Chapter (molecular genetics)

1. Match column I with column II and select the Column I Column II
correct option from the codes given below. A. 5-methyl (i) Not part of octamer
Column I Column II Uracil
A. Welcome (i) tRNA B. NHCs (ii) Higher level packaging
trust C. H1 histone (iii) Thymine
B. Jacob and (ii) Lac operon D. Octamer (iv) 8 histone
Monod
C. George (iii) Human genome
(1) A-(ii), B-(iii), C-(i), D-(iv)
gamow project
(2) A-(ii), B-(iii), C-(iv), D-(i)
D. Crick (iv) Genetic code
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i) 5. Match column I with column II and select the
(3) A-(iii), B-(ii), C-(iv), D-(i) correct option from the codes given below.
(4) A-(iii), B-(ii), C-(i), D-(iv)
Column I Column II
2. Match column I with column II and select the A. Messelson (i) S-strain and R-strain
correct option from the codes given below. and
Column I Column II stahl
A. Reminiscent (i) UGG B. Harshey (ii) P32 and S35
Of antiquity and
B. Coding (ii) Introns chase
strand C. Taylor (iii) N14 and N15
C. Tryptophan (iii) Similar to RNA D. Griffith (iv) Thymidine
D. Phenylalnine (iv) UUU
(1) A-(ii), B-(iii), C-(i), D-(iv) (1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i) (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i) (3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)

3. Match column I with column II and select the 6. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. Nondegenrate (i) 28srRNA and A. Fransic (i) DNA double helix
18srRNA crick model
B. No tRNA (ii) Methionine B. Wilkins and (ii) Central dogma
C. RNA pol III (iii) Stop codon Franklin
D. Nucleolus (iv) tRNA and snRNA C. Nucleosome (iii) Point mutation
D. Sickle cell (iv) 200base pair
anaemia
(1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(1) A-(ii), B-(i), C-(iv), D-(iii)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
4. Match column I with column II and select the
correct option from the codes given below.
 2

7. Match column I with column II and select the

correct option from the codes given below. 10. Match column I with column II and select the
Column I Column II correct option from the codes given below.
A. Pellet of (i) Non virulent
Harshey Column I Column II
Chase A. Rho factor (i) TERMINATION
experiment B. Sigma (ii) Elongation
B. S-strain (ii) Bacteria factor
DNA C. RNA (iii) Initiation
C. R-strain (iii) thermostable polymerase
D. Taylor (iv) 1958 D. Capping (iv) 5’ end
experiment
(1) A-(ii), B-(iii), C-(i), D-(iv) (1) A-(i), B-(iii), C-(ii), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i) (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i) (3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)

8. Match column I with column II and select the 11. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. DNA (i) Repair A. H-bond (i) Catalytic role
B. RNA (ii) Have uracil B. tRNA (ii) Adaptor molecule
C. Protein (iii) RNA C. rRNA (iii) Secondary Structure
D. QB (iv) Catlalyst D. 23s RNA (iv) Stable RNA
bacteriophage

(1) A-(i), B-(iii), C-(ii), D-(iv) (1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(i), B-(ii), C-(iv), D-(iii) (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i) (3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)

9. Match column I with column II and select the 12. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. Opening of (i) Lagging strand A. A-site on (i) A-site become empty
DNA in ribosome
replication B. P-site on (ii) t-RNA in initiation
ribosome step
B. Opening of (ii) Helicase
DNA in C. Peptide (iii) tRNA in elongation
bond step
Transcription
formation
C. Promoter (iii) RNA polymerase
D. Ribosome (iv) Elongation step in
binding
move translation
D. Okazaki (iv) Sigma factor
forward
fragment
(1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(1) A-(ii), B-(iii), C-(i), D-(iv)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
 3

13. Match column I with column II and select the 16. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. Yeast (i) Split gene A. 0.34 nm (i) Haploid
B. Skin cell (ii) Histones B. 2nm (ii) Distance between two
C. Streptococcus (iii) Lac operon base
D. E.coli (iv) Coupled Transcription C. 6.6 (iii) Diameter of DNA
and Translation billion base
pair
(1) A-(i), B-(iii), C-(i), D-(iv) D. 3.3 billion (iv) Diploid
(2) A-(i), B-(ii), C-(iv), D-(iii) base
(3) A-(iii), B-(ii), C-(iv), D-(i) pir
(4) A-(iii), B-(ii), C-(i), D-(iv)
(1) A-(ii), B-(iii), C-(i), D-(iv)
14. Match column I with column II and select the (2) A-(ii), B-(iii), C-(iv), D-(i)
correct option from the codes given below. (3) A-(iii), B-(ii), C-(iv), D-(i)
Column I Column II (4) A-(iii), B-(ii), C-(i), D-(iv)
A. Transcription (i) Nucleolus
B. Translation (ii) nucleus 17. Match column I with column II and select the
C. rRNA (iii) Cytoplasm correct option from the codes given below.
synthesis Column I Column II
D. DNA (iv) S-phase A. Ribose (i) aldose
replication B. Deoxyribose (ii) thymine
C. ATP (iii) Glycosidic bond
(1) A-(ii), B-(iii), C-(i), D-(iv) D. Adenosine (iv) Phosphoester bond
(2) A-(ii), B-(iii), C-(iv), D-(i) (1) A-(ii), B-(iii), C-(i), D-(iv)
(3) A-(iii), B-(ii), C-(iv), D-(i) (2) A-(ii), B-(iii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv) (3) A-(i), B-(ii), C-(iv), D-(iii)
(4) A-(iii), B-(ii), C-(i), D-(iv)
15. Match column I with column II and select the
correct option from the codes given below. 18. Match column I with column II and select the
correct option from the codes given below.
Column I Column II Column I Column II
A. CsCL (i) E.coli A. Adenosine (i) Two chain
density B. Adenylic acid (ii) Nuclotide
centifugation C. Polyadenylate (iii) Nucleoside
B. Transformation (ii) Vicia faba D. DNA (iv) Single chain
C. Mc carty and (iii) Streptococcus
Avery
(1) A-(ii), B-(iii), C-(i), D-(iv)
D. Taylor (iv) DNAse
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(ii), B-(iii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(i), B-(iii), C-(iv), D-(ii)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
 4

19. Match column I with column II and select the

correct option from the codes given below. 22. Match column I with column II and select the
Column I Column II correct option from the codes given below:
A. Antiparallel (i) Give mRNA Column I Column II
B. ANtiparallel (ii) Two strand of DNA I. DNA not a. Repeated
C. Tailing (iii) 3’ end open once in RNA
D. Splicing (iv) One trand DNA and Replication synthes
one strand RNA is occur
in transcription II. Origin b. End of
terminus
(1) A-(ii), B-(iii), C-(i), D-(iv) III. Terminus c. Centre of
(2) A-(ii), B-(iv), C-(iii), D-(i) replicon
(3) A-(iii), B-(ii), C-(iv), D-(i) IV. Primer d. RNA
(4) A-(iii), B-(ii), C-(i), D-(iv) I II III IV
(1) a b c d
20. Match column I with column II and select the (2) a d c b
correct option from the codes given below. (3) a c b d
(4) a c d b
Column I Column II
A. Stability of (i) Visible in Electron 23. Match column I with column II and select the
DNA microscope correct option from the codes given below for RNA:
B. Phosphate (ii) Stacking of base pair Column I Column II
C. Histidine (iii) Negative charge I. RNA pol I a. 18s rRNA
and lysine II. RNA pol II b. hnRNA
D. Beads on (iv) Positive charge III. RNA pol III c. 16s rRNA
string IV. RNA pol d. 5s rRNA
I II III IV
(1) A-(ii), B-(iii), C-(i), D-(iv) (1) a b c d
(2) A-(ii), B-(iii), C-(iv), D-(i) (2) a d c b
(3) A-(iii), B-(ii), C-(iv), D-(i) (3) a c b d
(4) A-(iii), B-(ii), C-(i), D-(iv) (4) a b d c

21. Match column I with column II and select the 24. Match column I with column II and select the
correct option from the codes given below: correct option from the codes given below:
Column I Column II
Column I Column II I. Lac z a. galactosidase
I. Loops in a. Nucleoid II. Lac a b. Permease
DNA III. Lac y c. Transacetylase
II. Quest to b. 1926 IV. Lac i d. Represson
detrmine I II III IV
genetic (1) a b c d
material (2) a d c b
III. Griffith c. 1928 (3) a c b d
IV. HGP d. 1920 (4) a c d b
I II III IV
(1) a b c d
(2) a d c b
(3) a c b d
(4) a c d b
 5

25. Match column I with column II and select the (4) a c d b

correct option from the codes given below:
Column I Column II 28. Match column I with column II and select the
I. Permease a. channel correct option from the codes given below:
II. Galactosidase b. Break Column I Column II
glycosidic I. AUG a. Stop codon
bond II. UUU b. Phenylalanine
III. Operator c. Repressor III. UGA c. Methionine
bind IV. UGG d. Tryptophan
IV. lactose d. Inducer I II III IV
I II III IV (1) b a c d
(1) a b c d (2) a d c b
(2) a d c b (3) c b a d
(3) a c b d (4) a c d b
(4) a c d b
29. Match column I with column II and select the
26. Match column I with column II and select the correct option from the codes given below:
correct option from the codes given below: Column I Column II
Column I Column II I. Cell free a. H.G khorana
I. DNA ligase a. Transcription synthesis of
II. Sigma b. Replication protein
factor II. Template b. Nirenberg
III. UTR c. ATP require free
IV. Charging of d. Efficient synthesis
tRNA translat III. Co polymer c. Severo ochoa
ion IV. George d. Triplet
I II III IV gamow synthesis
(1) a b c d I II III IV
(2) a d c b (1) a b c d
(3) a c b d (2) a d c b
(4) b a d c (3) b c a d
(4) b c d a
27. Match column I with column II and select the
correct option from the codes given below:
30. Match column I with column II and select the
Column I Column II correct option from the codes given below:
I. Post a. Eukaryotes Column I Column II
transcriptional I. 23s rRNA a. Nucleolus
level II. 28s RNA b. RNA pol III
regulation
III. 5s rRNA c. Catalyst in
II. Translation b. Release factor yeast
III. DNA c. Primase IV. 18s RNA d. Cytoplasm
replication I II III IV
IV. Transcription d. Promoter and (1) a b c d
structural (2) a d c b
gene (3) d c b a
I II III IV (4) b c d a
(1) a b c d
(2) a d c b
(3) a c b d
 6

31. Match column I with column II and select the 34. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. Dystrophin (i) Introns remove A. Satellite (i) Minisatellite
B. tRNA (ii) Largest gene DNA
C. hnRNA (iii) smallest B. Repetitive (ii) Repeats
D. Splicing (iv) nucleus DNA
C. Southern blot (iii) Transfer of DNA on
nylon memebrane
(1) A-(ii), B-(iii), C-(i), D-(iv)
D. DNA (iv) Non-coding
(2) A-(ii), B-(iii), C-(iv), D-(i)
fingerprinting
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(1) A-(ii), B-(iii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
32. Match column I with column II and select the
correct option from the codes given below. (3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iv), B-(ii), C-(iii), D-(i)
Column I Column II
A. Non coding (i) Not code for RNA
DNA 35. Match column I with column II and select the
correct option from the codes given below.
B. introns (ii) Not translated in
protein
C. UTR (iii) Not present in Column I Column II
processed RNA A. Degenerate (i) Primary structure
amin
D. Promoter (iv) Part of Transcription
acid
unit
B. tRNA (ii) More than one codon
(1) A-(i), B-(iii), C-(ii), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i) C. mRNA (iii) ANticodon
(3) A-(iii), B-(ii), C-(iv), D-(i) D. Universal (iv) Exception
mitochondria
(4) A-(iii), B-(ii), C-(i), D-(iv)

33. Match column I with column II and select the (1) A-(ii), B-(iii), C-(i), D-(iv)
correct option from the codes given below. (2) A-(ii), B-(iii), C-(iv), D-(i)
Column I Column II (3) A-(iii), B-(ii), C-(iv), D-(i)
A. Monocitronic (i) More than two gene in (4) A-(iii), B-(ii), C-(i), D-(iv)
transcriptional unit
B. Polycistronic (ii) Single gene in 36. Match column I with column II and select the
structural unit correct option from the codes given below.
C. Operon (iii) Regulator gene and Column I Column II
many strictiral gene A. Three (i) One amino acid less
D. Repressor (iv) preotein deletion
B. Three (ii) Frame shift addition
addtiion
(1) A-(ii), B-(i), C-(iii), D-(iv)
C. Two (iii) One amino acid more
(2) A-(i), B-(iv), C-(iii), D-(ii)
addition
(3) A-(i), B-(iii), C-(iv), D-(ii)
D. Substitution (iv) Numner of amnio acid
(4) A-(iii), B-(ii), C-(i), D-(iv)
not change

(1) A-(i), B-(iii), C-(ii), D-(iv)

(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
 7

(4) A-(iii), B-(ii), C-(i), D-(iv) 40. Match column I with column II and select the
correct option from the codes given below.

37. Match column I with column II and select the Column I Column II
correct option from the codes given below. A. RNA (i) 5.8 s RNA
Column I Column II Poly I
A. Adaptor (i) Crick B. RNA poly I (ii) hnRNA
hypothesis C. RNA pol II (iii) 28s RNA
B. Meischer (ii) DNA fingerprinting D. RNA pol (iv) tRNA
C. Alec jeffery (iii) Nuclein III
D. SNP (iv) Mutation
(1) A-(i), B-(ii), C-(iii), D-(iv) (1) A-(i), B-(iii), C-(ii), D-(iv)
(2) A-(i), B-(iii), C-(iv), D-(ii) (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i) (3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)

38. Match column I with column II and select the 41. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. PPLO (i) Double strand DNA A. Peptide (i) No tRNA comes
B. E.coli (ii) DNA in cytoplasm formation
B. Ribosome (ii) Two amino acid close
C. Human cell (iii) Lac operon
to each other
D. Lambda (iv) Semiconservative
C. UTR (iii) 80 type protein
phage proof
D. Stop codon (iv) Part of mRNA
at A-
(1) A-(ii), B-(iii), C-(i), D-(iv)
site
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(ii), B-(iii), C-(i), D-(iv)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
39. Match column I with column II and select the
(4) A-(iii), B-(ii), C-(i), D-(iv)
correct option from the codes given below.
Column I Column II
42. Match column I with column II and select the
A. EUchromatin (i) Gene cloning correct option from the codes given below.
B. Heterochromatin (ii) Transcriptionally
Column I Column II
active
A. rRNA (i) catalyst
C. Arabdopsis (iii) Dense stain
B. tRNA (ii) Primary striucture
D. BAC (iv) Genome sequencing
C. mRNA (iii) Read code on mRNA
D. hnRNA (iv) Nascent RNA
(1) A-(ii), B-(iii), C-(i), D-(iv)
(1) A-(i), B-(iii), C-(ii), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(4) A-(iii), B-(ii), C-(i), D-(iv)
 8

43. Match column I with column II and select the 46. Match column I with column II and select the
correct option from the codes given below. correct option from the codes given below.
Column I Column II Column I Column II
A. Storage of (i) DNA A. Capping (i) Removal of intron
genetic B. Tailing (ii) Guanosine tri
information phosphate at 5’ end
B. Transfer of (ii) Three degree C. Splicing (iii) 3’ end poly A tail
genetic functional D. cDNA (iv) Reverse transcription
information
C. tRNA (iii) RNA (1) A-(ii), B-(iii), C-(i), D-(iv)
D. UGA (iv) Present in mRNA (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(i), B-(iii), C-(iv), D-(ii) (4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(i), B-(iii), C-(ii), D-(iv)
(3) A-(iii), B-(ii), C-(iv), D-(i) 47. Match column I with column II and select the
(4) A-(iii), B-(ii), C-(i), D-(iv) correct option from the codes given below.
Column I Column II
44. Match column I with column II and select the A. Release (i) For start codon
correct option from the codes given below. factor
Column I Column II B. Gene (ii) Termination
A. ELSI (i) Cloning C. cDNA (iii) DNA sequence
B. Southern (ii) HGP D. Initiator (iv) Smaller than main
blotting tRNA DNA
C. YAC (iii) DNA fingerprinting (1) A-(ii), B-(iii), C-(i), D-(iv)
D. Sequencing (iv) Sanger method (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(ii), B-(iii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i) 48. Match column I with column II and select the
correct option from the codes given below.
(4) A-(iii), B-(ii), C-(i), D-(iv)
Column I Column II
45. Match column I with column II and select the A. RNA (i) Protein
correct option from the codes given below. polymerase
B. Poly A tail (ii) nucleotide
Column I Column II C. Adenylic (iii) Nucleic acid
A. 5’ to 3’ (i) Coding strand acid
B. 3’ to 5’ (ii) 5’ to 3’ direction D. Uridine (iv) Nucleoside
C. Transcription (iii) Template strand
D. Translation (iv) N to C terminal (1) A-(i), B-(iii), C-(ii), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(i), B-(iii), C-(ii), D-(iv)
(4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)
 9

49. Match column I with column II and select the

correct option from the codes given below. Column I Column II
Column I Column II A. Histones (i) Primer
A. X-ray (i) Central dogma B. 16s rRNA (ii) Eukaryotes
crystallography C. Primase (iii) Only in 5’ to 3
B. Watson and (ii) Wilkins and franklins direction
crick D. DNA (iv) RNA poly
C. Crick (iii) Complimentary base polymerase
pairing
D. Reverse (iv) Retro virus (1) A-(ii), B-(iv), C-(i), D-(ii)
transcription (2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(1) A-(ii), B-(iii), C-(i), D-(iv) (4) A-(iii), B-(ii), C-(i), D-(iv)
(2) A-(ii), B-(iii), C-(iv), D-(i)
(3) A-(iii), B-(ii), C-(iv), D-(i)
(4) A-(iii), B-(ii), C-(i), D-(iv)

50. Match column I with column II and select the

correct option from the codes given below.