Assignment no. 4 Name: Ezra Nicollete L.
Mira
Extemporaneous
Compounding Year and Sec. 2-Y1-1 Date: 11/13/2024
Questions:
A. Extemporaneous Compounding
1. Describe briefly the following American organizations based on its purpose or objectives
5. Describe briefly the following American organizations based on its purpose or objectives
PCCA
• Raise awareness about the importance of compounding within the pharmacy profession
and quality/security measures regarding the compounded medicines
• Provide students with an opportunity to develop their knowledge in designing and
preparing compounded medicines
NCPA
• Represents the professional and proprietary interests of independent community
pharmacists and vigorously promotes and defends those interests.
Alliance for Pharmacy Compounding
• ensuring the rights of physicians to prescribe, of pharmacists to prepare, and of patients
to
take personalized medication solutions to meet their unique health care needs.
5. Describe briefly the following American organizations based on its purpose or objectives
PCCA
• Raise awareness about the importance of compounding within the pharmacy profession
and quality/security measures regarding the compounded medicines
• Provide students with an opportunity to develop their knowledge in designing and
preparing compounded medicines
NCPA
• Represents the professional and proprietary interests of independent community
pharmacists and vigorously promotes and defends those interests.
Alliance for Pharmacy Compounding
• ensuring the rights of physicians to prescribe, of pharmacists to prepare, and of patients
to
take personalized medication solutions to meet their unique health care needs.
5. Describe briefly the following American organizations based on its purpose or objectives
PCCA
• Raise awareness about the importance of compounding within the pharmacy profession
and quality/security measures regarding the compounded medicines
• Provide students with an opportunity to develop their knowledge in designing and
preparing compounded medicines
NCPA
• Represents the professional and proprietary interests of independent community
pharmacists and vigorously promotes and defends those interests.
Alliance for Pharmacy Compounding
• ensuring the rights of physicians to prescribe, of pharmacists to prepare, and of patients
to
take personalized medication solutions to meet their unique health care needs.
PCCA- Helps pharmacists who make customized medicines for patients. They provide high-
quality ingredients, tools, and training. The group works to teach people how important
compounding is in pharmacy and stresses the need to make sure compounded medicines are safe
and effective. They also give pharmacists and students the chance to learn how to make
medicines that are tailored to each patient's needs, helping them provide the best care possible.
Professional Compounding Centers of America. (n.d.). Home. PCCA. Retrieved November 12,
2024, from https://www.pccarx.com
NCPA- Serves as the voice of independent community pharmacists in the United States. They
work to protect and promote the interests of local pharmacies by making sure laws and policies
help support their businesses. NCPA offers resources, education, and help with running a
pharmacy to improve patient care. They also work to pass laws that make sure independent
pharmacies stay an important part of the healthcare system.
National Community Pharmacists Association. (n.d.). Home. NCPA. Retrieved November 12,
2024, from https://www.ncpa.org
Alliance for Pharmacy Compounding (APC)- The APC is an advocacy organization
committed to supporting the practice of pharmaceutical compounding. It advocates for the
fundamental rights of physicians to prescribe, pharmacists to prepare, and patients to receive
personalized medications that meet their unique healthcare needs. The APC emphasizes patient
safety by promoting high standards in compounding practices and works to ensure that policies
and regulations are in place to maintain the effectiveness and safety of compounded medicines.
The organization helps to ensure that patients can trust the medications they receive from
compounding pharmacies.
Alliance for Pharmacy Compounding. (n.d.). Home. APC. Retrieved November 12, 2024, from
https://www.apcinet.org
2. Give the advantages and disadvantages of practicing extemporaneous compounding.
Extemporaneous compounding helps make medicines that are tailored to the specific needs of
patients, especially children who need special doses or forms of medicine. It can also be cheaper
and provide access to medicines that are not available. However, there are risks. The wrong dose
can be given, the medicine may not last as long or work properly, and mixing different
ingredients can cause problems. Children, especially babies, are more at risk for side effects.
Also, in some countries, there may not be enough rules or training for people who make these
medicines, which can lead to mistakes. To make sure compounded medicines are safe and
effective, there needs to be better training, control, and rules for how they are made.
Yuliani, S. H. et al. (2024). Prevalence, risk, and challenges of extemporaneous preparation for
pediatric patients in developing nations: A review. Journal of Pediatric Pharmacology &
Therapeutics, 29(1), 15-23.
Retrieved November 12, 2024, from https://pmc.ncbi.nlm.nih.gov/articles/PMC10058853/
3. Compute for the following practice problems in compounding (select 5 questions only):
a) How much (in milliliters) of a 1% stock solution of a certified red dye should be used in
preparing 4000 mL of a mouthwash that is to contain 1: 20,000 w/v of the certified red
dye as a coloring agent?
b) Prepare 30 mL of a 5 mg/mL oral phenobarbital solution using phenobarbital available
from the manufacturer in a 65 mg/mL solution that comes in 1-mL vials. How much
stock solution will be required?
c) Clindamycin is available in a solution of 150 mg/mL. How much of this solution is
required to make 15 mL of a clindamycin ophthalmic injection 1 mg/0.1 mL?
d) A physician prescribes an ophthalmic suspension to contain 100 mg of cortisone acetate
in 8 mL of normal saline solution. The pharmacist has on hand a 2.5% suspension of
cortisone acetate in normal saline solution. How much (in milliliters) of this and how
much normal saline solution (in milliliters) should be used in the prescribed suspension?
e) How much white petrolatum (in grams) should be mixed with 250 g of 5% and 750 g of
15% sulfur ointments to prepare a 10% ointment?
f) How much 2.5% hydrocortisone cream (in grams) should be mixed with 360 g of 0.25%
cream to make a 1% hydrocortisone cream?
g) How much (in grams) of salicylic acid should be added to 75 g of a polyethylene glycol
ointment to prepare an ointment containing 6% w/w of salicylic acid?
