27112024 Class Practice Test # 02 Target Batch
ORGANIC CHEMISTRY [Topic : AMINO ACIDS]
Time : 45 Min. (for JEE-Mains & Advanced 2025) Max. Marks : 60
01. A hexapeptide has the composition Ala,Gly,Phe,Val3. Both the N-terminal and C-
terminal units are Val. Cleavage of the hexapeptide by chymotrypsin gives two dif-
ferent tripeptides, both having Val as the N-terminal group. Among the products of
random hydrolysis is a Ala-Val dipeptide fragment. What is the primary structure of
the hexapeptide ?
*(a) Val-Gly-Phe-Val-Ala-Val (b) Val-Ala-Phe-Val-Gly-Val
(c) Val-Gly-Ala-Val-Phe-Val (d) Val-Phe-Val-Ala-Gly-Val
02. Both cysteine and methionine are chiral L-amino acids that incorporate a single
sulfur. The C-2 configuration is ‘S’ in methionine, but ‘R’ in cysteine. Why ?
(a) biosynthesis of cysteine proceeds by inversion at C-2.
(b) the sulfur in cysteine prevents zwitterion formation.
*(c) the sulfur atom in methionine is remote from C-2 and does not influence the
sequence rule.
(d) the sulfur atom in cysteine is remote from C-2 and does not influence the
sequence rule.
03. Consider the following statements about amino acids.
(A) The amino acids that constitute proteins are all L-amino acids.
(B) Among the twenty common amino acids that constitute proteins, glycine is the
only one that does not possess a chiral centre.
(C) An important and sensitive test for the detection of L-amino acids is the ninhy-
drin colour test.
(D) Nitrous acid liberates nitrous oxide from amino acids.
Which of the following statements is correct?
(a) a, b and d (b) a, c and d (c) b and d *(d) a, b and c
Integer Type #
04. List-I [Natural amino acid] List-II (One Letter Code)
A. Glutamic acid 1. Q
B. Glutamine 2. W
C. Tyrosine 3. E
D. Tryptophan 4. Y
In the matching A is matched with No. ‘n1’ , B is matched with No. ‘n2’ , C is
matched with No. ‘n3’ , D is matched with No. ‘n4’ .
4
Calculate the value of in
i 1
i ? Ans : 25
05. A tetrapeptide has –COOH group on alanine .This produces glycine (Gly), valine
(Val), phenyl alanine (Phe) and alanine (Ala), on complete hydrolysis. For this tet-
rapeptide, the number of possible sequences (primary structures) with –NH2 group
attached to a chiral center is ? Ans : 4
Contact Number : 9889655556 page no # 3
06. List-I [Natural amino acid] List-II [One Letter Code]
A. Arginine 1. D
B. Aspartic acid 2. N
C. Asparagine 3. A
D. Alanine 4. R
In the matching A is matched with No. ‘n1’ , B is matched with No. ‘n2’ , C is
matched with No. ‘n3’ , D is matched with No. ‘n4’ .
4
Calculate the value of in
i 1
i ? Ans: 24
07. The total number of distinct naturally occurring amino acids obtained by complete
acidic hydrolysis of the peptide shown below are n1 and the number of distinct -
aminoacids not occuring (in the list of 20 -AA) are n2 .
Calculate the value of |n2 – n12| :
Ans : 2
08. Total number of tripeptides possible by mixing of valine and proline is __: Ans : 8
09. In alanylglycylleucylalanylvaline, the sum of no. of chiral carbons, the no. of sp3
carbons and number of peptide linkages is ___ Ans : 22
10. A peptide synthesized by the reaction of one molecule each of Glycine, Leucine,
Aspartic acid and Histidine will have ‘n1’ no. of chiral carbons , ‘n2’ no. of sp2
3
carbons and ‘n3’ no. of peptide linkages . Calculate the value of in ? Ans : 28
i 1
i
11. The total number of negative charge in the tetrapeptide, Gly-Glu-Asp-Tyr, at pH
12.5 will be ___ ? Ans : 4
12. The sum of number of nitrogen atoms, carbon atoms and number of chiral carbons
present in peptide, Ile-Arg-Pro, is ___ ? Ans : 27
13. A short peptide on complete hydrolysis produces 3 moles of glycine (G), two moles
of Leucine (L) and two moles of valine (V) per mole of peptide. The sum of number of
peptide linkages and number of sp3 c’s in it are ? Ans : 27
14. A pentapeptide has –COOH group on alanine .This produces glycine (Gly), valine
(Val), Serine (Ser), phenyl alanine (Phe) and alanine (Ala), on complete hydrolysis.
For this pentapeptide, the number of possible sequences (primary structures) with
–NH2 group attached to a chiral center is ? Ans :18
15. A decapeptide (Mol. wt. 796) on complete hydrolysis gives glycine (Mol. wt. 75),
alanine and phenylalanine. Glycine contributes 47.0% to the total weight of the
hydrolysed products. The number of glycine units present in the decapeptide is :
Ans : 6 page no # 4
Contact Number : 9889655556
