Department of Physiology, Jhalawar Medical College, Jhalawar

General Physiology completion Test of Batch 2024

Date – 16/12/2024 Time – 10:00 am to 10:45 am Max. Marks - 100

Name…………………………………………………………………………………………………………… Roll no………………………………..

Note – All questions carry equal five marks (5), there is negative marking (-2) for each incorrect answer.

To be filled by evaluator -
No. of Correct Answers (5 each) No. of Incorrect Answers (-2 each) Marks Obtained Sign of evaluator

Write one choice (A / B / C / D) in given space only at the side of each question –

Q. Multiple Choice Questions (MCQs) -

All are seen more in ECF except-
1 C
a. Na+ b. Cl- c. Mg+2 d. HCO3-
Which curve best illustrates the volume change caused by
immersion of the cell into a mixture of aqueous solution of
200 mOsm/L NaCl and 200 mOsm/L of glycerol?
a. A
2 b. B B
c. C
d. D
e. E
ATP synthesis is totally blocked in a cell. How will the value of membrane rest potential change?
3 A. First it will increase and then decrease. B. First it will decrease, then increase C
C. It will disappear D. It will be considerably increased
Excitable tissue at rest is least permeable to -
4 A
a. Na+ b. K+ c. Ca+2 d. Cl-
Feed forward control system is employed during the regulation of:
5 C
a. Blood volume b. pH c. Temperature d. Blood pressure
A 40-year-old man presents to his primary care physician with a 2-month history of intermittent
upper abdominal pain shortly after eating. He is referred to a specialist, and upper
gastrointestinal endoscopy is performed. The endoscopy reveals a peptic ulcer. He is prescribed
6 omeprazole, a gastric proton pump inhibitor. What type of cell membrane transport is inhibited B
by this medication?
A. Facilitated diffusion B. Primary active transport
C. Secondary active transport D. Simple diffusion
The term "homeostasis" was coined by:
7 A
A. W.B. Cannon B. Claude Bernard C. William Harvey D. Charles Sherrington
Effectiveness of homeostatic control system is assessed by –
8 A
A. Gain B. Loss C. Recovery D. Improvement in function
Gap junctions are present plentily in –
9 C
A. Intestine B. Brain C. Heart D. Kidney
Equilibrium potential for an ion is calculated using:
10 C
A. Gibbs-Donnan equation B. Goldmann equation C. Nernst equation D. Katz equation
What is the effect on membrane, if extracellular concentration of K+ is decreased-
11 A. Decreased magnitude of RMP B. Increased negativity of membrane B
C Increased magnitude of RMP D. Decreased negativity of membrane

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 Department of Physiology, Jhalawar Medical College, Jhalawar
General Physiology completion Test of Batch 2024
Date – 16/12/2024 Time – 10:00 am to 10:45 am Max. Marks - 100

Name…………………………………………………………………………………………………………… Roll no………………………………..

Note – All questions carry equal five marks (5), there is negative marking (-2) for each incorrect answer.

If an experimental drug changed the resting membrane potential of a cell from –70 mV to –50
mV, what effect would this have on the rate of sodium and potassium diffusion across the cell
membrane when the membrane is permeable to these electrolytes?
12 A. Rate of sodium diffusion into cell is ↑ and Rate of potassium diffusion into cell is ↓ B
B. Rate of sodium diffusion into cell is ↓ and Rate of potassium diffusion into cell is ↑
C. Rate of sodium diffusion into cell is ↓ and Rate of potassium diffusion into cell is ↔
D. Rate of sodium diffusion into cell is ↔ and Rate of potassium diffusion into cell is ↓
Ion channels in the cell membrane are lined by:
13 A
a. Protein b. Carbohydrates c. Lipid d. Polysaccharide
Excitable tissue at rest is least permeable to:
14 A
a. Na+ b. K+ c. Ca+2 d. Cl-
True about facilitated diffusion are all except:
15 a. Occur in direction of concentration gradient b. Does not require energy C
c. Occur in direction opposite to electrical gradient d. Facilitated by charge of molecule
Which of the following transport mechanisms is not rate limited by an intrinsic Vmax?
16 A. Facilitated diffusion via carrier proteins B. Primary active transport via carrier proteins D
C. Secondary co-transport D. Simple diffusion through protein channels
A clinical study is conducted to determine the actions of an unknown test solution on red blood
cell volume. One millilitre of heparinized human blood is pipetted into 100 millilitres of test
solution and mixed. Samples are taken and analysed immediately before and at 1-second
intervals after mixing. The results show that red blood cells placed into the test solution
immediately swell and burst. Which of the following best describes the tonicity and osmolarity of
17 C
the test solution?
A) Hypertonic; could be hyperosmotic, hypo-osmotic, or iso-osmotic
B) Hypertonic; must be hyperosmotic or hypo-osmotic
C) Hypotonic; could be hyperosmotic, hypo-osmotic, or iso-osmotic
D) Hypotonic; must be hyperosmotic or hypo-osmotic
Which of the following is used in exocytosis?
18 A
a. Ca+2 b. Mg+2 c. Na+ d. K+
Microelectrode analysis of nerve fibre bioelectrical activity revealed, that its membrane potential
equals 90 mV. Its initial rest potential was 85 mV. What process occurs in this case?
19 D
A. Repolarization B. Depolarization
C. Overshoot D. Hyperpolarization
Which statement is incorrect?
A) The term “homeostasis” describes the maintenance of nearly constant conditions in the body
B) In most diseases, homeostatic mechanisms are no longer operating in the body
20 B
C) The body’s compensatory mechanisms often lead to deviations from the normal range in some
of the body’s functions
D) Disease is generally considered to be a state of disrupted homeostasis

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