THE HINDHU COLONY
CHELLAMAL VIDYALAYA
SENIOR SECONDARY
SCHOOL
CHEMISTRY
INVESTIGATORY
PROJECT
REDUCTION OF ALCOHOL FROM
HUMAN
BODY USING ESTERIFICATION
SUBMITTED BY
MUHAMMAD NABEEL
SHEIK PASHA
CONTENTS
INTRODUCTION
OBJECTIVE
THEORY
CALCULATIONS
MATERIALS REQUIRED
PROCEDURE
PRECAUTIONS
OBSERVATIONS
FUTURE SCOPE
CONCLUSIONS
BIBILIOGRAPHY
INTRODUCTION
All across the globe consumption of alcohol is
increasing day by day or rather has become a
trend. Youngsters have fallen for this and start
consuming alcohol at an early age. Alcohol
consumption gives rise to serious health disorders.
It damages liver causing liver cirrhosis, shows a
range short term and long term disorders on brain
and central nervous system and also affects the
reproductive organs. To tackle these problems and
to contribute to a healthy living, we came up with
this idea of reducing alcohol to ester using
esterification reaction
OBJECTIVE
This report is pertaining to a method to remove
alcohol from stomach before significant amount
enters blood. The objective is to determine if
organic acids can react efficiently with alcohol in an
esterification reaction to possibly eliminate it from
human body. The experiment are carried out with a
view to create some sort of medication where the
quantity of acetic acid would be
consumable.Intention behind this project is not to
motivate alcohol consumption but to provide an
easy remedy for critical conditions.
THEORY
What is esterification reaction?
Alcohols can combine with many kind of acids to form
esters. When no type of acid is specified, the word ester is
assumed to be carboxylic ester,the ester of an alcohol and
carboxylic acid. The reaction called the Fishcher reaction,is
characterised by the combining of an alcohol and an acid
(with an acid catalyst) to yield an ester plus water
Under appropriate conditions, inorganic acids also react
with alcohols to form esters. To form these esters, a wide
variety of specialised reagents and conditions can be used.
REACTIONS INVOLVED IN THIS EXPERIMENT :-
Actual esterification reaction:-
CH3COOH + C2H5OH CH3COOC2H5 +
H20
Pre- esterification reaction:-
ethanoic acid calcium hydroxide calcium acetate water
Modified esterification reaction:-
2C2H5OH + CH3COO-Ca-OOCCH3
2CH3COOC2H5 + Ca(OH)2
ethanol calcium acetate ethyl acetate calcium hydroxide
CALCULATIONS
Some necessary calculations to obtain right pH of solution
i.e. in the range of 3-4 are as follows
1.100 ml of vinegar contains approximately 0.067-0.087
moles of acetic acid depending upon manufacturer.
2.According to FDA, recommended consumption of calcium
for an adult is 3g per day.
3.Now, 100ml = 0.067 moles of acetic acid 1000 ml = 0.67
moles of acetic acid 4.Approximately the concentration of
vinegar should be 0.03M using,
M1V1 = M2V2
we obtain the quantity of vinegar as,
(1000x0.03)/0.67 = 44ml
5.Permissible value for
Ca(OH)2 is 0.02 moles,
the amount of Ca(OH)2 required is,
0.02x74 ,
where molecular weight of Ca(OH)2 is 74
=1.48g
MATERIALS
REQUIRED
1.Conical flask
2.Burette
3.Pipette
4.2% KMnO4 Solution
5.Two samples of Acetic acid(Vinegar and laboratory
sample)
6.1.48g of Calcium hydroxide
7.10Ml Ethanol
8.Test tube
9.Test tube holder
10.Weighing machine
PROCEDURE
Preparation of Solution:
1. Take 44ml of vinegar in a beaker.
2. Measure 1.48g of calcium hydroxide using digital
weighing machine.
3. Add the measured calcium hydroxide to the beaker
containing vinegar and stir well.
4. With the help of pH paper or pH indicator solution,
measure the pH of solution ( we had used pH meter for
accuracy )
5. Obtained pH should be in the range of 3-4.
Titration against Potassium Permanganate:
1. Take 10 ml of this solution and add 10 ml alcohol to it.
2. Fill the burette with 2% KMnO4.
3. Perform the titration till brown color is obtained.
PRECAUTIONS
1.Wear your safety goggles.
2.Sulfuric acid can cause chemical burns that may seriously
damage skin and/or eyes. Wear goggles and gloves and
avoid contact. If contact occurs, wash with copious amounts
of water. A paste made with baking soda (sodium
bicarbonate) and water can also be applied to the skin to
neutralize the acid.
3.The carboxylic acids and alcohols used in this experiment
can be irritating with foul odors. Keep all reagents in the
fume hood to minimize odors.
4. Read from the lower meniscus while during the titration
OBSERVATIONS
1. Alcohol reacts with acetate ions present in the solution to
form ester , ethyl acetate.
2. It is indicated by citric flavor aroma of ester instead of
pungent smell of acetic acid.
3. Observations from titration suggest complete reduction of
alcohol to ester because:
i. Potassium permanganate (KMnO4) which is purple
coloured acts as indicator and end point achieved
purple brown colour.
ii. Formation of MnO2- ions gives the brown colour
FUTURE SCOPE OF THE
PROJECT
1. Alcohol can be harmful to human body as it can cause
heavy damage to liver like liver cirrhosis. Short term effects
on brain include dizziness, drowsiness, loss of
concentration, and mood swings. Long term effects include
memory loss, strokes and concussions. Reproductive
organs are also damaged due to consumption of alcohol. It
can result in infertility or physical deformities and mental
retardation in case of foetus.
2. Esters having negligible effect on our health proves to be
a better alternative than alcohol in our body.
3. Using edible colors and artificial flavors it can be used in
pharmaceutical and drug industry.
4. Usually our liver takes 10-12 hours to reduce alcohol but
this might prove to be a faster solution.
Conclusion
The formed brown colour indicates the complete
reduction of alcohol to ester. In case of vinegar the
colour obtained is less while in laboratory sample it
is more dark because of the high content of
ethanoic acid in laboratory sample and presence of
other chemical contents in commercial vinegars.
This process has a large future scope due to the
wide spread misuse of alcohol in the present day
and it is also used in drug industry and
pharmaceutical industry.
BIBILIOGRAPHY
https://csef.usc.edu/History/2009/Projects/
S0512.pdf
https://www.scribd.com/presentation/
423491445/Chemistry-Project
