2005 Icrp 96 Protecting People Against Radiation Exposure in The Event of A Radiological Attack
2005 Icrp 96 Protecting People Against Radiation Exposure in The Event of A Radiological Attack
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ICRP Publication 96
Abstract–This report responds to a widely perceived need for professional advice on radiolog-
ical protection measures to be undertaken in the event of a radiological attack. The report,
which is mainly concerned with possible attacks involving Ôradioactive dispersion devicesÕ,
re-affirms the applicability of existing ICRP recommendations to such situations, should they
ever occur.
Many aspects of the emergency scenarios expected to arise in the event of a radiological
attack may be similar to those that experience has shown can arise from radiological accidents,
but there may also be important differences. For instance, a radiological attack would prob-
ably be targeted at a public area, possibly in an urban environment, where the presence of
radiation is not anticipated and the dispersion conditions commonly assumed for a nuclear
or radiological emergency, such as at a nuclear installation, may not be applicable.
First responders to a radiological attack and other rescuers need to be adequately trained
and to have the proper equipment for identifying radiation and radioactive contamination,
and specialists in radiological protection must be available to provide advice. It may be pru-
dent to assume that radiological, chemical, and/or biological agents are involved in an attack
until it is proven otherwise. This calls for an Ôall-hazardÕ approach to the response.
In the aftermath of an attack, the main aim of radiological protection must be to prevent the
occurrence of acute health effects attributable to radiation exposure (termed ÔdeterministicÕ
effects) and to restrict the likelihood of late health effects (termed ÔstochasticÕ effects) such as
cancers and some hereditable diseases. A supplementary aim is to minimise environmental
contamination from radioactive residues and the subsequent general disruption of daily life.
The report notes that action taken to avert exposures is a much more effective protective mea-
sure than protective measure the provision of medical treatment after exposure has occurred.
Responders involved in recovery, remediation and eventual restoration should be subject to
the usual international standards for occupational radiological protection, which are based on
ICRP recommendations, including the relevant requirements for occupational dose limitation
established in such standards. These restrictions may be relaxed for informed volunteers
undertaking urgent rescue operations, and they are not applicable for voluntary life-saving
actions. However, specific protection measures are recommended for female workers who
may be pregnant or nursing an infant.
iii
ICRP Publication 96
The immediate countermeasures to protect the public in the rescue phase are primarily car-
ing for people with traumatic injuries and controlling access. Subsequent actions include respi-
ratory protection, personal decontamination, sheltering, iodine prophylaxis (if radioiodines
are involved), and temporary evacuation. In the recovery phase, the relocation and resettle-
ment of people may be needed in extreme cases. This phase may require remedial action,
including cleanup, management of the resulting radioactive waste, management of any human
remains containing significant amounts of radioactive substances, and dealing with remaining
radioactive residues.
The guidance given in relation to public protection is based solely on radiological protection
considerations and should be seen as a decision-aiding tool to prepare for the aftermath of a
radiological attack. It is expected to serve as input to a final decision-making process that may
include other societal concerns, consideration of lessons learned in the past (especially these
involving the public perception of the risks posed by radioactive contamination) and the par-
ticipation of interested parties.
A radiological attack could also be the cause of radioactive contamination of water, food,
and other widely consumed commodities. This possible outcome is considered unlikely to lead
to significant internal contamination of a large number of people owing to the large amounts
of radioactive material that would be required to cause high levels of contamination of water,
food, and other commodities. Nonetheless, the report recommends radiological criteria for
restricting the use of commodities under such circumstances.
The report concludes by reiterating that the response to radiological attacks should be
planned beforehand following the customary processes for optimisation of radiological pro-
tection recommended by ICRP, and that optimised measures should be prepared in advance.
Such plans should result in a systematic approach that can be modified if necessary to take
into account the prevailing conditions and to invoke actions as warranted by the circum-
stances. Many potential scenarios clearly cannot induce immediate severe radiation injuries.
Therefore, in order to prevent over-reaction, response measures prepared in advance should
reflect the real expected gravity of the various possible scenarios.
Ó 2005 ICRP. Published by Elsevier Ltd. All rights reserved.
Keywords: RDD; Contamination; Radiation protection; Intervention; Emergency planning
iv
ICRP Publication 96
Guest Editorial
In the wake of the terrorist attacks on the US World Trade Center, the subway
systems in Spain and Japan, embassies, nightclubs, and hotels, authorities have be-
come acutely aware of a need to re-assess existing philosophies and assumptions.
This report examines the changes that need to be made to existing radiation emer-
gency planning and protection so that it is applicable to terrorist events.
There are several clear and unique lessons from the recent attacks. The first of
these is the intent of terrorists to stage multiple events simultaneously. Previously,
most radiation emergency plans were directed towards a single event. The second
factor, which is new in radiation protection, is the concept of suicide scenarios. A
third lesson is that we can no longer rely on historical factors such as the probability
of failure rates of various components to predict the likelihood of an event. Terror-
ists deliberately choose improbable or unexpected events. The fourth lesson is the
realisation of a terrorist event combining multiple hazardous agents. Thus, planning
for a radiological incident alone is an outmoded concept and authorities need to be
able to recognise and respond to a situation where there is a combined chemical, bio-
logical, and radiological hazard.
A final lesson is that emergency planning cannot be static. As plans are developed
for detection devices and stockpiles to neutralise biological and chemical threats, we
must assume that the terrorists will simply move on to other ideas and we might ex-
pect the radiological threat to grow.
Much has been written about Ôdirty bombsÕ, but this is only one of several forms
that nuclear terrorism may take. While we instinctively expect to know when a ter-
rorist event has occurred, this is not necessarily the case. A powdered radioactive
material could be spread in a populated area and the terrorists could just wait until
it had been spread by foot traffic and discovered incidentally. This could certainly
cause great concern and economic damage, but is unlikely to represent a significant
public health threat.
One of the major points to emerge from this report is that prevention of exposure
is much more practical and effective than medical treatment post exposure. In the
event of a large release of radioactivity into the environment, sheltering, control
of the food chain, and, if necessary, evacuation can result in dose reduction or pro-
tection factors of up to 100. In contrast, with current medical treatment of both
external exposure and internal contamination, survival or dose reduction can be af-
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ICRP Publication 96
vi
CONTENTS
ABSTRACT..................................................................................................... iii
GUEST EDITORIAL...................................................................................... v
PREFACE ....................................................................................................... 1
GLOSSARY .................................................................................................... 11
1. INTRODUCTION....................................................................................... 21
1.1. Background .............................................................................................. 21
1.2. Aim of the report ..................................................................................... 23
1.3. Intended audience..................................................................................... 24
7. COMMUNICATION .................................................................................. 83
REFERENCES................................................................................................ 107
PREFACE
After the events of 11 September 2001, there has been increasing worldwide appre-
hension about the use of radioactive materials in malicious acts. Members of the
public, the media, and political representatives have become concerned about the
possible malicious use of sources and devices containing radioactive materials (for
instance, by dispersing their radioactive content into the community and threatening
the public health and welfare of inhabitants), the possibility of sabotage attacks on
nuclear facilities (where the malicious aim might be to trigger uncontrolled releases
of radioactive materials), and the potential diversion of nuclear weapon material and
its use in improvised nuclear devices. These speculations on the possibility of what
has been termed a Ôradiological attackÕ have triggered a widespread request for pro-
fessional advice, not only on radiation and nuclear security measures aimed at pre-
venting the attacks from occurring, but also on radiological protection measures to
be undertaken should such an event actually take place. It has been recognised that
existing radiological emergency contingency plans may be insufficient to cope with
the consequences of an attack, as these have mainly focused on accident scenarios
that can generally be anticipated rather than on a premeditated malicious setting
deliberately designed to maximise harm, anxiety, and fear.
In response to the need for advice, the International Commission on Radiological
Protection (ICRP), hereinafter referred to as the Commission, at its 2003 meeting in
Vienna, Austria, established a Task Group to prepare a report providing advice on
protecting people against radiation exposure in the aftermath of a radiological at-
tack. In preparing the report, the main aim of the Task Group was to collect relevant
available recommendations on radiological protection that might be applicable in
the event of such malicious events, and to provide guidance on additional measures
that may be necessary to prepare for and respond to them. The Task Group consid-
ered, but did not assess, the potential or the likelihood of possible scenarios for a
radiological attack. It assumed that a breach of security leading to a radiological at-
tack could actually occur and, on this basis, developed advice on how to intervene
with actions aimed to protect the health of both responders and members of the pub-
lic in accordance with the CommissionÕs recommendations.
It is neither the CommissionÕs role nor the intention of this report to provide a uni-
versal prescription for solving the difficult issues that authorities may face in the con-
text of a radiological attack. The recommendations in the report are generic in
nature and may require modification in light of prevailing social and political cir-
cumstances, as well as availability of resources at the time and location where such
an event might occur. The report assumes that authorities have allocated a priori
responsibilities for the management of the potential radiological emergency resulting
from an attack, and its recommendations build upon the existing concepts and pro-
cesses for emergency preparedness and response to radiological emergencies that
have been developed over many years. It is stressed that all contingency planning
to provide for such emergencies must contain elements of flexibility, as the nature
and types of emergencies will vary greatly both in scale and in the type of response
required.
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ICRP Publication 96
For the preparation of the report, the Task Group met in the headquarters of the
Swedish Radiation Protection Authority in Stockholm, Sweden on 10–12 October
2003, and the headquarters of the International Atomic Energy Agency in Vienna,
Austria on 20–22 April 2004. The Commission wishes to express its appreciation
for the support received from those who hosted those meetings.
The membership of the Task Group was as follows:
At its meeting in Vienna in April 2004, the Commission authorised the inclusion of
the Task GroupÕs draft report on the ICRP website for consultation. The report ap-
peared on the web on 17 May 2004. Many comments were received from the profes-
sional community. These served for a further review and revision of the draft report.
The Commission is extremely grateful to those who dedicated their time and profes-
sional expertise to examine the draft and contributed their comments. At its meeting
in Suzhou, China on 16 October 2004, the Commission finally approved the revised
Task Group report for publication in the Annals of the ICRP.
The membership of the Commission during the period of preparation of this re-
port was:
2
EXECUTIVE SUMMARY
(a) This report is intended to respond to a widespread need for professional advice
on measures to be undertaken should a radiological attack occur, leading to the
malicious exposure of people to radiation and radioactive substances. Its main
aim is to provide recommendations for protecting rescuers and affected members
of the public against the radiation exposure that might be incurred as a result of such
an event. The report re-affirms the applicability of the standing CommissionÕs recom-
mendations to those potential situations. The Commission expects that relevant
intergovernmental international organisations would establish guidance to assist na-
tional authorities to develop arrangements to deal with radiological attacks on the
basis of the advice given in this report.
(b) The recommendations in the report are conceptually applicable to a wide range
of conceivable attacks. These include the utilisation of radioactive materials for mali-
cious purposes, such as the use of a Ôradioactive dispersion deviceÕ (RDD), the sab-
otage of a nuclear facility to cause an unplanned release of radioactive material, and,
in extreme cases, the detonation of an improvised nuclear device (IND). Since inter-
national advice and recommendations for dealing with nuclear accidents exist, and
given that the special nuclear materials needed to construct an IND are not expected
to be readily available, this report is mainly concerned with radiological attacks
involving RDDs.
(c) Preparing for and responding to a radiological attack should be aimed at pro-
tecting people against arbitrary and unpredictable radiation exposure situations.
Where national authorities have emergency plans in place for radiological accidents,
the recommendations in the report provide additional or supplemental guidance. It
should be noted, however, that although many aspects of the possible emergency sce-
narios resulting from a radiological attack may be similar to those arising from
radiological accidents, these two types of emergencies differ in many respects. One
difference is that a radiological attack would most likely be targeted at a public area,
possibly located in an urban environment, where the presence of radiation or radio-
active material is not anticipated and where there may be limited preparedness for
responding with radiological protection measures. Moreover, the non-urban envi-
ronmental dispersion conditions commonly assumed for planning emergencies in nu-
clear facilities may not be applicable to urban scenarios. The characterisation of the
radiation source and its impact would probably be different as well. In addition, par-
ticular issues associated with the malicious character of the event, such as the crim-
inal investigation that is likely to follow, will have an influence on the emergency
planning and response.
(d) Planning for radiological protection in the aftermath of a radiological attack
requires the establishment of appropriate programmes at both local and national lev-
els. These programmes need to ensure that first responders and rescuers are ade-
quately trained and have the proper equipment to identify the presence of
radiation and radioactive contamination, and that radiation protection specialists
are available to advise local and other relevant authorities. Whenever there is cred-
ible indication that an emergency is in fact a malicious attack, it may be prudent to
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ICRP Publication 96
assume that radiological, chemical, and/or biological agents are involved until pro-
ven otherwise. Therefore, if such credible indication exists, the situation calls for the
adoption of an all-hazard approach to the response, which should be based on uni-
versal precautions combined with a prompt capability to identify all hazards present.
This approach needs extensive co-ordination and co-operation of the responsible
institutions, as well as experts in the fields of biological, chemical, and radiological
threats and their associated hazards.
(e) Radiological attacks are characterised by the presence of radioactive sub-
stances. The quantity describing the amount of radioactive substances is the (radio)
activity.1 According to their activity, radioactive substances emit radiation that may
expose both members of the public and rescuers coming to their aid. Radiation may
be delivered from sources outside the body (external exposure) or by radioactive sub-
stances that may be incorporated into the body via inhalation, ingestion, or through
open wounds or the skin (internal exposure). The potential health consequences
caused by the exposure will depend on the amount of radiation received, the types
of radiation involved, and the organs exposed. The amount of radiation exposure
is measured in terms of the radiation dose2 incurred by the affected individual.
(f) In most postulated scenarios associated with a radiological attack, radiation
doses incurred by the majority of exposed people will probably be relatively small,
perhaps lower than the typically elevated levels of the background radiation that
is ubiquitous in nature, e.g. of the order of tens of millisieverts or less. Nonetheless,
it is assumed that low radiation doses have the potential to induce some health effects
(termed ÔstochasticÕ effects), such as cancer and hereditable harm, that may become
manifest many years after the exposure. The probability of occurrence of stochastic
effects is very small, although it is assumed to increase proportionally with dose, and
at low doses, the such effects are unlikely to be detectable. Conversely, people
1
Activity is a quantity measured in units termed ÔbecquerelsÕ (although, in the past, the unit ÔcurieÕ was
– and still is – widely used). One becquerel represents an extremely small activity (conversely, 1 Ci
represents a significant amount of activity as it equates to 37 thousand million becquerels).
2
Dose is the relevant quantity for expressing the amount of radiation exposure. The radiation dose
received by any substance, including human tissues, is termed Ôabsorbed doseÕ and is assessed in units
called ÔgraysÕ (in the past, the unit ÔradÕ was used). Different types of radiation have different effectiveness to
induce damage, and different organs and tissues have different sensitivity to radiation exposure. Therefore,
the absorbed dose has to be weighted to take account of these differences. The quantities resulting from the
absorbed dose weighting for taking into account the effectiveness of various radiation types and the
sensitivity to radiation of various organs and tissues are termed Ôequivalent doseÕ and Ôeffective doseÕ,
respectively, and are both measured in a unit termed ÔsievertÕ (in the past, the unit ÔremÕ was used). The
equivalent dose, which is used to express tissue and organ doses, and the effective dose, which is used for
assessing the whole body implications, can only be employed for ÔnormalÕ radiation protection purposes,
i.e. for situations causing relatively low doses that may merely induce low-probability delayed health
effects, and cannot be formally used to express high doses. As these radiation protection quantities are not
directly measurable, instruments for assessing doses in people or in the ambience are usually calibrated
against defined operational quantities (termed Ôpersonal dose equivalentÕ and Ôambient dose equivalentÕ)
that correspond approximately to the radiation protection quantities and are formally used for verification
of compliance. For reasons of simplification, the report only uses equivalent dose, effective dose and the
unit termed ÔmillisievertÕ (mSv), which is a submultiple of the sievert equal to a thousandth of a sievert (one
mSv equates to 100 thousandths of 1 rem or 100 millirem).
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ICRP Publication 96
(perhaps only a small number) could also be exposed to high radiation doses, e.g. of
the order of thousands of millisieverts. If such dose levels are incurred, clinically vis-
ible health effects (termed ÔdeterministicÕ effects) are almost certain to appear, usually
as burns and other tissue reactions, within days of the exposure. Deterministic effects
affect the functioning of tissues and organs with a severity that increases with dose.
In severe cases, they can cause the death of exposed individuals. In radiological at-
tacks with RDDs, only people closer to the event may incur the high doses required
to induce deterministic effects (and only if large amounts of activity were involved).
People affected by the detonation of an IND, and under some conditions, those af-
fected by the radiological consequences of an act of sabotage in a nuclear installa-
tion, are more likely to be subject to high doses. The effects of different radiation
doses and the likelihood of observable consequences are summarised in Table 1.
(g) The relationship between exposure routes, protective actions, and response
phases in the aftermath of a radiological attack will vary depending on the specific
circumstances. Exposure routes include: direct exposure to the source, source frag-
ments or a damaged facility; external exposure from deposited contamination and
contaminated skin and clothes; external exposure and internal contamination from
the plume of dispersed radioactive substances; inhalation of resuspended material;
inadvertent ingestion of contamination; and ingestion of contaminated food and
water. The response phases are usually classified as rescue, recovery, and restoration.
A large number of protective measures are available, some specific for each phase
and some covering various phases.
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ICRP Publication 96
(h) The aim of the protective measures must be to prevent deterministic effects and
restrict the likelihood of stochastic effects. In addition to protecting people against
the unpredictable exposure situations that will be created by an attack, the objectives
include minimising the overall impact in terms of environmental contamination and
general disruption, and attempting to restore normality as quickly as possible. The
response must essentially be to: identify and characterise the emergency situation;
provide medical care for injured people; attempt to avoid further exposures; gain
control of the situation; prevent the spread of radioactive materials; provide accurate
and timely information to the public; and institute a process for returning to normal-
ity, while dealing with psychological issues, such as distress, and misattribution and
fear of illness, which will be major concerns. In the immediate response phase, exclu-
sion distances usually employed in relation to explosives are a good starting point for
controlling the site for radiation levels, and typical precautions at medical facilities
for infectious agents are sufficient as a starting point for handling people that may
be contaminated with radioactive material. It is emphasised that taking actions to
avert exposures is much more effective than possible medical treatment after expo-
sure has occurred. Treatment after an exposure is liable to reduce the number of
health effects slightly (e.g. by a factor of approximately 2–3); in comparison, inter-
ventions with protective actions to avert the exposure occurring is likely to reduce
the number of health effects by up to several orders of magnitude (e.g. by factors
of approximately 10–1000).
(i) Responders undertaking recovery and restoration operations should be pro-
tected according to normal occupational radiological protection standards, and
should not exceed internationally accepted occupational dose limits. This restriction
may be relaxed for informed volunteers undertaking urgent rescue operations, and is
not applicable for volunteered life-saving actions whenever the benefit to others
clearly outweighs the rescuerÕs own risk. However, since specific protection measures
have been recommended for female workers who may be pregnant or are nursing an
infant, and taking account of the unavoidable uncertainties surrounding early re-
sponse measures in the event of a radiological attack, female workers in those con-
ditions should not be employed as first responders undertaking life-saving or other
urgent actions. The recommended dose guidance values for restraining the occupa-
tional exposure of responders are shown in Table 2.
(j) The immediate countermeasures to protect the public in the rescue phase are
primarily caring for people with traumatic injuries and controlling access to the
scene, and subsequently providing affected people with respiratory protection mea-
sures and, whenever necessary and feasible, minimising the possible spread of con-
tamination with radioactive material. Caring for people should be supported by
triage and disposition following quick assessments of the approximate dose incurred
and the physiological status of the affected people. Subsequent urgent actions in this
phase include: personal decontamination, sheltering, iodine prophylaxis (if radioio-
dines are involved), and temporary evacuation. In the recovery phase, definitive relo-
cation and resettlement may be needed in extreme cases. Each of these
countermeasures has a degree of associated penalties, and typically would provide
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ICRP Publication 96
Other operations, including recovery and restoration Normal occupational dose limits apply,
operations i.e.:
a limit on effective dose of 20 mSv/year,
averaged over 5 years (i.e., a limit of
100 mSv in 5 years), with the further
provision that in any single year:
the effective dose should not exceed
50 mSv and
the equivalent dose should not exceed
– 150 mSv for the lens of the eye
– 500 mSv for the skin (average dose
over 1 cm2 of the most highly irradi-
ated area of the skin), and
– 500 mSv for the hands and feet
*
Under conditions that may lead to doses above normal occupational exposure limits, workers should
be volunteers and should be instructed in dealing with radiation hazards to allow them to make informed
decisions. Female workers who may be pregnant or nursing should not participate in such operations.
the most benefit if the reduction of the avertable dose for the affected population was
around the levels shown in Table 3.
(k) The recovery phase may require restoration and clean up, the safe management
of the radioactive waste remaining from these operations, management of corpses
containing significant amounts of radioactive substances, and dealing with long-term
prolonged exposure situations caused by remaining radioactive residues. In the latter
case, the recommended generic criteria for justifying intervention with radiation pro-
tection measures are shown in Table 4.
(l) The quantitative recommendations given in Tables 3 and 4 cannot always be
used directly as quantities such as equivalent dose and effective dose are not directly
7
ICRP Publication 96
measurable. They should be used as the basis for developing (at the planning stage)
operational intervention levels expressed in directly measurable quantities. The rec-
ommended guidance is based solely on radiological protection considerations and
should be seen purely as a decision-aiding tool aimed at helping the competent
authorities to prepare for the aftermath of a radiological attack. The guidance is ex-
pected to serve as input to a final, and usually wider, decision-making process that
may include other societal concerns, consideration of lessons learned in the past
from other events, and the participation of interested parties. Simplification of crite-
ria and corresponding training and exercising would allow for better implementa-
tion; however, during the response to an actual event, emergency managers may
need to take other factors, such as other hazards or specific conditions, into account
in operational decisions.
(m) A potential consequence of a radiological attack is the radioactive contam-
ination of goods such as water, food, and other commodities for public consump-
tion. This possible outcome, however, is unlikely to lead to significant internal
contamination of a large number of people because of the large amounts of radio-
active material that would be required to reach high levels of contamination in
mass-produced or -distributed supplies. While the levels of contamination of con-
sumer goods and the resulting levels of annual effective dose could be very low, the
effective control of contamination for radiation protection purposes could become
amenable and warranted above certain activity concentration levels. The values in
Table 5 represent the approximate levels of activity concentration in contaminated
substances above which control for radiological protection purposes can be consid-
ered in case of a radiological attack. Consumer goods with activity concentration
below the levels in Table 5 are excluded from the scope of the recommendations in
this report.
(n) An intergovernmental international consensus on radiological criteria for
radionuclides in commodities was recently reached under the aegis of the IAEA. Na-
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tional authorities may wish to take these criteria into account for deciding on control
measures following a radiological attack.
(o) The process of radiological protection intervention measures in the aftermath
of a radiological attack should result in a systematic and flexible approach to the re-
sponse, taking into account the conditions present and invoking protective actions as
warranted by the circumstances. It is helpful to understand that there are recommen-
dations that are always applicable, others that are often applicable, and others that
are only applicable in the most severe circumstances (for instance, as many potential
scenarios clearly cannot induce immediate severe radiation injuries, recommenda-
tions on these effects are not always applicable). In order to prevent over reaction,
it is essential that radiological protection decisions reflect the magnitude of the radio-
logical attack.
9
GLOSSARY
Absorbed dose
The absorbed dose is defined as the average energy absorbed from radiation by a
tissue, organ, or the whole body per unit mass of such tissue, organ, or the whole
body (ICRP, 1991a, Paragraph S2). The special name for the unit of absorbed dose
is ÔgrayÕ (Gy) which is equivalent to J/kg (another unit used in some countries is the
ÔradÕ; 100 rad = 1 Gy).
Accident
Any unintended event, including operating errors, equipment failures, or other
mishaps, the consequences or potential consequences of which are not negligible
from the point of view of radiological protection.
Action level
The level of dose rate or activity concentration above which remedial actions or
protective actions should be carried out in chronic exposure or emergency exposure
situations.
Activation
The production of radionuclides by irradiation.
Activity
The quantity activity, A, for an amount of radionuclide in a given energy state
at a given time is defined as A = dN/dt, where dN is the expectation value of the
number of spontaneous nuclear transformations from the given energy state in the
time interval dt. The unit of activity is the reciprocal second, termed the ÔbecquerelÕ
(Bq).
Collective dose
An expression for the total radiation dose incurred by a population, defined as the
product of the number of individuals exposed to a source and their average radiation
dose. The collective dose is expressed in man-sieverts (man-Sv).
Committed dose
The committed dose (absorbed dose, equivalent dose, or effective dose) is defined
as the summation integral of the dose rate over time, from the time of exposure to a
time that if not specified will be taken to be 50 years for adults.
Control
In the context of control over radioactive sources, the Commission uses the term
ÔcontrolÕ to include checking, monitoring, and verifying the safety and security of
such sources, as well as ensuring that corrective or enforcement measures are taken
if the results indicate the need for them. Control over radiation sources should be
commensurate with their potential for causing radiation induced health effects.
Countermeasure
An action aimed at alleviating the consequences of an accident.
Critical group
A group of members of the public that is reasonably homogeneous with respect to
its exposure for a given radiation source and given exposure pathway, and is typical
of individuals receiving the highest effective dose or equivalent dose (as applicable)
by the given exposure pathway from the given source.
Decontamination
The removal or reduction of contamination by a physical or chemical process.
Deterministic effect
A radiation effect for which a threshold level of dose generally exists above which
the severity of the effect is greater for a higher dose.
3
The duration of the exposure is an important consideration since protraction of the dose influences
the threshold dose at which deterministic effects may appear. If the interventions are fully effective, the
averted dose is numerically equal to the projected dose, but these are conceptually different quantities (vide
infra). However, it may be appropriate to express the intervention level in terms of a projected dose for
that pathway rather than an averted dose. Intervention may not be fully effective, either because the dose
has already been received, or because the intervention itself may only partly reduce the total projected
dose.
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Dose
A measure of the radiation received or ÔabsorbedÕ by a target. The quantities termed
Ôabsorbed doseÕ, Ôorgan doseÕ, Ôequivalent doseÕ, Ôeffective doseÕ, Ôcommitted equivalent
doseÕ, or Ôcommitted effective doseÕ are used, depending on the context. The modifying
terms are often omitted when they are not necessary for defining the quantity of interest
(see Radiation dose, Absorbed dose, Equivalent dose, Effective dose, and Avertable
dose).
Dose limit
The value of the effective dose or the equivalent dose to individuals from con-
trolled practices that shall not be exceeded.
Effective dose
The quantity E, defined as a summation of the tissue equivalent doses, each mul-
tiplied by the appropriate tissue weighting factor
X
ET ¼ wT H T
where HT is the equivalent dose in tissue T and wT is the tissue weighting factor for
tissue T. From the definition of equivalent dose, it follows that
X X
ET ¼ wT wR DT;R ;
R
where wR is the radiation weighting factor for radiation R and DT,R is the average
absorbed dose in the organ or tissue T. The unit of effective dose is J/kg, termed
the ÔsievertÕ (Sv).
Emergency plan
A description of the objectives, policy, and concept of operations for the response
to an emergency, and of the structure, authorities, and responsibilities for a system-
atic, co-ordinated, and effective response.
Employer
Within the context of this document, the employer will be the legal person with
recognised responsibility, commitment, and duties towards workers in the rescue
operations, i.e. in his or her ÔemploymentÕ, by virtue of a mutually agreed relationship.
A self-employed person is regarded as being both an employer and a worker.
Equivalent dose
The quantity HT,R, defined as
H T;R ¼ DT;R wR ;
where DT,R is the absorbed dose delivered by radiation type R averaged over a tissue
or organ T, and wR is the radiation weighting factor for radiation type R.
When the radiation field is composed of different radiation types with different val-
ues of wR, the equivalent dose is
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X
H T;R ¼ wR DT;R :
The unit of equivalent dose is J/kg, termed the ÔsievertÕ (Sv).
Exposure
The Commission uses the term ÔexposureÕ in a generic sense to mean the process of
being exposed to radiation or radionuclides, the significance of exposure being deter-
mined by the resulting radiation dose (ICRP, 1991a, Paragraph S4). Exposure is the-
refore the act or condition of being subject to irradiation. Exposure can be either
external (irradiation by sources outside the body) or internal (irradiation by sources
inside the body). Exposure can be classified as either normal or potential exposure;
either occupational, medical, or public exposure; and, in intervention situations such
as those following a radiological attack, either emergency or chronic exposure. The
term ÔexposureÕ is also used in radiodosimetry to express the amount of ionisation
produced in air by ionising radiation.
Exposure pathways
The routes by which radioactive material can reach or irradiate humans.
Intake
The process of taking radionuclides into the body by inhalation, ingestion, or
through the skin.
Intervening organisation
An organisation designated or otherwise recognised by a government as being
responsible for managing or implementing any aspect of an intervention.
Intervention
Any action intended to reduce or avert exposure or the likelihood of exposure to
sources that are not part of a controlled practice or which are out of control as a
consequence of an accident or, within the context of this document, are involved
in a radiological attack.
Intervention level
The level of avertable dose at which a specific protective action or remedial action
is taken in an emergency exposure situation or a chronic exposure situation.
Investigation level
The value of a quantity such as effective dose, intake, or contamination per unit
area or volume at or above which an investigation should be conducted.
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Ionising radiation
For the purposes of radiation protection, radiation capable of producing ion pairs
in biological material(s).
Justification
In the aftermath of a radiological attack, one of the issues is to justify the intro-
duction (or continuation) of disruptive countermeasures or what is termed Ôjustifica-
tion of interventionÕ. The Commission recommends that any proposed intervention
should do more good than harm, i.e. the reduction in detriment resulting from the
reduction in dose should be sufficient to justify the harm and the costs, including so-
cial costs, of the intervention.
Monitoring
The measurement of dose or contamination for reasons related to the assessment
or control of exposure to radiation or radioactive substances, and the interpretation
of the results.
Occupational exposure
All exposures of workers incurred in the course of their work, e.g. the exposure of
rescuers.
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ICRP Publication 96
Orphan sources
The terms ÔorphanÕ and ÔorphanedÕ source have been used internationally to de-
scribe a radioactive source that is not under regulatory control, either because it
has never been under regulatory control, or because it has been abandoned, lost, mis-
placed, stolen, or transferred without proper authorisation.
Projected dose
Projected dose is the dose estimated for the population at risk for each exposure
pathway without taking possible protective actions into account.
Protective action
An intervention intended to avoid or reduce doses to members of the public in
chronic or emergency exposure situations.
Public exposure
Exposure incurred by members of the public from radiation sources, excluding
any occupational or medical exposure and the normal local natural background
radiation, but including exposure from authorised sources and practices and from
intervention situations, e.g. the situation resulting from a radiological attack.
radiation). There has been an imprecise use of the terms ÔradiationÕ and ÔradioactiveÕ
to qualify sources potentially amenable for malicious uses. A source of radiation
exposure is not necessarily ÔradioactiveÕ. Typical non-radioactive radiation sources
are various types of electrical generators of radiation, such as x-ray apparatus and
particle accelerators, which emit radiation while in operation but their emitting prop-
erties cease as soon as the electricity supply is cut. Conversely, radioactive radiation
sources (or radioactive sources in short) emit radiation because they contain radioac-
tive substances. Typical examples of radioactive sources are the sealed capsules con-
taining radionuclides, such as 60Co and 137Cs, which never cease to emit radiation
with decaying intensity. Of these, only those containing a significant amount of radio-
active substance are relevant for malicious purposes. (The amount of radioactivity in-
volved in a radiological attack is usually referred to as the Ôsource termÕ.) In summary,
all radiation sources, be they radioactive or non-radioactive, may be a safety concern;
conversely, not all radiation sources but just those radioactive sources containing a
significant amount of radioactive substance may also be a security concern in relation
to potential terrorist attacks.
Radiation dose
The health significance of a radiological attack will be determined by the resulting
radiation exposure of people and, specifically, by the radiation dose incurred by the indi-
viduals being irradiated. The Commission uses the term Ôradiation exposureÕ in a broad
sense to mean the process of being exposed to radiation or radioactive material and,
specifically, it uses the term Ôradiation doseÕ as a generic name expressing the amount
of energy received by matter from radiation exposure (ICRP, 1991a, Paragraph S4).
With different qualifiers, the term ÔdoseÕ gives rise to various dosimetric quantities.
Radioactive half-life
For a radionuclide, the time required for the activity to decrease, by a radioactive
decay process, by half.
Radioactive residues
The Commission uses the term Ôradioactive residuesÕ to mean radioactive materials
that have remained in the environment from early operations (including past prac-
tices) and accidents (ICRP, 1991a, Paragraph 219).
Radioactive waste
The Commission uses the term Ôradioactive wasteÕ to mean any (radioactive) mate-
rial that will be or has been discarded, being of no further use (ICRP, 1997c, Para-
graph 3).
in the press as a Ôdirty bombÕ, but may be more properly referred to as an ÔRDDÕ. The
dispersion of radioactive material into the environment may be achieved without
explosives, by opening the source container if the material is dispersible, or process-
ing the source to make it dispersible.
Residual dose
Residual dose4 is the remaining dose from each pathway (projected dose minus
averted dose). For long-term decisions that would usually involve prolonged exposure
situations to residual doses that may remain long after the event, the relevant quantity
is the annual (effective) dose, which can be presented as: the existing annual dose, i.e.
the summation of the annual doses caused by all the persisting sources of prolonged
exposure already existing in the human habitat where the situation occurs; the addi-
tional annual dose, i.e. the annual dose that is added to the existing annual dose as
a result of the event; and/or the averted annual dose, i.e. the annual dose that is re-
moved from the existing annual dose by the protective actions that might be taken.
Risk
A multi-attribute quantity expressing hazard, danger, or chance of harmful or
injurious consequences associated with actual or potential exposures. It relates to
quantities such as the probability that specific deleterious consequences may arise
and the magnitude and character of such consequences.
Safety assessment
A review of the aspects of design and operation of the intervention following a
radiological attack that are relevant to the radiological protection of people, includ-
ing analysis of the provisions for safety and protection established, and the analysis
of risks associated with the event.
4
While each intervention is judged on its merits, the sum of residual doses from all pathways after
implementation of protective actions should be kept under review because of the possibility of serious
deterministic health effects.
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Source
The Commission uses the term ÔsourceÕ to indicate what may cause radiation
exposure. Sources range from nuclear installations and other nuclear facilities usu-
ally holding huge inventories of radioactive fission and activation products, to sim-
ple sealed sources of radioactive materials. The term is also used more generally to
indicate the cause of exposure to radiation or to radionuclides in radioactive sub-
stances, and not necessarily an individual physical source of radiation. For in-
stance, if radioactive materials are released from an installation to the
environment, the installation as a whole may be regarded as a source; if they
are already dispersed in the environment, the portion of them to which people
are exposed may be considered a source.
Supervised area
Any area not designated as a controlled area but which is kept under review for
occupational exposure conditions, even though specific protective measures and
safety provisions are not normally needed.
5
The Commission defines activity as the average number of spontaneous nuclear transformations
taking place per unit time in an amount of radioactive substance (ICRP, 1991a, Paragraph 37).
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ICRP Publication 96
Worker
Any person who works, whether full time, part time or temporarily, for an em-
ployer and who has recognised rights and duties in relation to occupational radiation
protection. A self-employed person is regarded as having the duties of both an em-
ployer and a worker. Rescuers are regarded as workers.
20
1. INTRODUCTION
1.1. Background
(1) Over the years, the CommissionÕs recommendations (ICRP, 1959, 1964, 1966,
1977, 1991a) have presumed that, as a precondition for proper radiological protection,
sources of radiation exposure have to be subject to proper security measures. This pre-
sumption is reflected in the International Basic Safety Standards for Protection against
Ionizing Radiation and for the Safety of Radiation Sources (IAEA, 1996a), usually
referred to as the ÔBSSÕ, which follow ICRP recommendations and require that the con-
trol over sources shall not be relinquished under any circumstances. Source security is a
necessary, although not sufficient, condition to ensure source safety. If a source is not
secure, it is not safe; conversely, sources that are secure are not necessarily safe.
(2) Secured sources can, and have, become unsecured through a variety of circum-
stances. Historically, in the most common cases, control over the source was relin-
quished inadvertently, and then the source was misused, without any premeditated
malicious intent. In other cases, many sources have been found to be orphaned of
any control and were therefore completely unsecured. A relatively large number of
radiological accidents have occurred because of these unintentional breaches in
source security or because an orphan source was inadvertently found. The detailed
causes and consequences of some of these accidents have been reported internation-
ally (IAEA, 1988a, 1996b, 1998a,b,c, 2000a,b,c, 2002a,b).
(3) These cases of inadvertent breaches of source security have provided an indi-
cation of what might occur if radioactive materials were used intentionally to create
harm. There is the potential for premeditated criminal breaches in source security
that may eventually lead to the malicious use of radioactive materials. An example
of a radiological attack based on this type of scenario could be the deliberate disper-
sion of the radioactive content of a source in a public area. Such an event has the
potential for exposing people to radiation and causing significant environmental
contamination, which would require specific radiological protection measures. Be-
fore the events of 11 September 2001, information on security of radioactive sources
had been published internationally (IAEA, 1998c, 1999a, 2001c). Following these
events, the issue has been re-addressed both at international level (IAEA, 2003c)
and also by various national organisations (e.g. HPS, 2004; NCRP, 2001), particu-
larly regarding the possibility of malicious uses of unsecured radioactive sources.
An international Code of Conduct on Safety and Security of Radioactive Sources
has been established recently (IAEA, 2001b, 2004a), with a clearly defined scope
of ÔdangerousÕ sources (IAEA, 2003b). More recently, international agreement has
been reached on guidance for export/import of sources (IAEA, 2004e) in order to
implement relevant requisites in the Code. The Commission expects that adherence
to the CodeÕs requirements will strengthen the necessary control of radioactive
sources – a prerequisite to ensure that they are properly secured.
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(4) There are a number of reasons why radiation is of unique concern in relation
to malicious events. On the negative side, radiation is perceived as a mysterious
pollutant, and past experience with radiation emergencies has shown that there
are problems in dealing with this perception. The public have, in general, exagger-
ated fears because radiation is invisible and odourless, and its effects may only be
apparent hours, days, weeks, or even many years after exposure. Radiological at-
tacks are more likely than other malicious events to give rise to psychological
problems among members of the public, public officials, and professionals in other
fields because of the fear of radiation and a misunderstanding of its consequences.
The perceived risk is a major contributor to the anxiety and fear that may be in-
duced by a malicious act – an extra dimension presenting additional challenges to
those who will have to manage the health consequences of such an event. There
will be difficulties in responding to a radiological attack because those who handle
the situation at an early stage, if not appropriately trained, will share much of the
anxiety and fear about radiation, and they will probably have little experience in
dealing with such an emergency.
(5) Relatively low levels of radiation exposure, such as those that will likely remain
after a radiological attack, are often mistakenly viewed as a substantial hazard, and
this is the main element in the creation of anxiety and fear. Contrary to public per-
ception, radiation is actually a weak carcinogen. At low levels of exposure, the health
risks attributable to radiation, such as the risk of developing cancer, are very low –
so low that any potential effect is, in fact, undetectable by epidemiological
techniques. Radiation protection professionals should, however, do whatever they
reasonably can to constrain unjustified radiation exposure of people, because the
prevalent scientific opinion is that for protection purposes, a small but finite risk
of deleterious effects should be attributed to radiation exposure above background
levels, even at low levels. Unfortunately, justifiable radiation protection efforts with-
out proper communication with the public can themselves become a contributor to
anxiety and fear as people can misinterpret them as an indication that they are sub-
ject to a high risk.
(6) On the positive side, in comparison with biological or chemical attacks, the
area over which radioactive contamination occurs can be readily delineated if appro-
priate radiation measurement instruments are available (with the possible exception
of contamination due to some alpha-emitting radioisotopes). Moreover, radiation is
one of the most studied agents in toxicology and medicine, including its carcinogenic
potential, and therefore many sources of information on the health effects of radia-
tion are available. As a result of these studies, sound criteria for conventional radio-
logical emergencies have already been developed, which are relevant and can be
applied in the event of a radiological attack. Furthermore, it is generally recognised
that there would be far fewer fatalities following a radiological attack, in contrast to
the number of immediate fatalities that could be caused by biological or chemical
agents, or simply by a large explosive blast.
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(7) The main aim of this report is to provide radiological protection recommenda-
tions for protecting peopleÕs health in the aftermath of a radiological attack. These
recommendations are based on conceivable scenarios of specific radiological attacks
aimed at exposing people to radiation, or contaminating the environment, creating
anxiety and fear, and resulting in disruption. The report does not address the means
by which the source of radiation was obtained by the attackers.
(8) The Commission notes that whether or not an ÔattackÕ is the trigger of a
situation of radiological concern, the aftermath of either intended or unintended
events of this type are, in fact, very similar: namely, the potential for unexpected
exposure of people to radiation. The intent that caused the radiological condition
may be different, but the outcome and the necessary response actions are essen-
tially the same. However, there are differences between an emergency that may
arise from an accident and those associated with a radiological attack. These dif-
ferences are described in the report. If a radiological attack were to occur,
authorities and radiological protection experts could be faced with a situation
where radiation and/or radioactive material are in a place where it was not ex-
pected or explicitly planned to be. Whatever the scenario, the final objectives
should be to protect people in unpredictable exposure situations, to minimise
the impact, and to quickly restore the situation to normal. When this fact is rea-
lised, the response must essentially:
identify and characterise the emergency situation;
provide medical care to those affected;
quickly attempt to avoid further exposures;
gain control of the situation;
prevent the spread of radioactive materials;
provide accurate and timely information to the public; and
begin the process of returning to normality.
(9) Capabilities need to be in place to ensure the effective performance of these
response actions, and relevant international requirements and guidance have been
established (IAEA, 2002c, 2003b). These capabilities will include those that are
generic for all types of emergencies (e.g. continuously available emergency contact
points, command and control, public communication arrangements, initial all-
hazards assessment) and those that are specific to radiological emergencies (e.g.
radiological assessment, monitoring, and protection capabilities) (IAEA, 1997c;
1999b; 2000d). These capabilities will need to be applied in a systematic and flex-
ible manner to perform the response functions effectively according to the event
scenario.
(10) It is to be noted that the recommendations in the report are mainly based
on the scientific assessment of the health risks associated with radiation exposure
that may arise in the aftermath of certain scenarios involving radiological attacks.
However, some members of the public and sometimes their political representatives
may have alternative views on the radiation risks attributable to such situations.
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ICRP Publication 96
This usually results in differently perceived needs for response and a different level
of protection. The desired level of protection may be higher than that for other
exposure situations. For instance, the risk attributable to living in areas with typ-
ically elevated natural radiation exposures are usually ignored by society, while
relatively minor exposures to artificial radioactive residues remaining in the envi-
ronment are a cause of concern and sometimes prompt unnecessary protective ac-
tions. This reality of social and political attributes, generally unrelated to
radiological protection, will influence the final decision on the level of protection
following a radiological attack.
(11) Therefore, the Commission emphasises that this report should be viewed as
providing decision-aiding recommendations based principally on scientific consider-
ations of radiological protection, rather than an automatic formula for making deci-
sions. The recommendations in the report, therefore, provide supplemental guidance
and input to a wider decision-making process that may include: other societal con-
cerns; other hazards that may be present; consideration of lessons learned in the past
from other events; and the participation of relevant stakeholders. The process of
planning for radiological attacks should result in a systematic, yet flexible, approach
to the response, taking the conditions present into account, and invoking protective
actions as warranted by the circumstances.
(12) The Commission intends this report to be of help to responsible officials, reg-
ulatory bodies, and advisory agencies with competence in emergency response – in
particular, those agencies dealing with possible radiological attacks and their after-
math at local, regional, national, and international level. The report provides guid-
ance to these bodies on the fundamental principles on which appropriate
intervention with protective actions may be undertaken in response to such an event.
Different conditions are likely to apply in different countries, and the Commission,
therefore, wishes to emphasise that the report should not be viewed as a universal
text on radiological protection in the event of a radiological attack.
(13) The Commission recognises that one of the problems to be faced in rela-
tion to the types of situations discussed in this report is the lack of a common
understanding on the basic issues among scientists, decision makers, the media,
and the public at large. Unfortunately, since the events of 11 September 2001,
reactions of many people have created some confusion in the comprehension of
the security concerns associated with radioactive substances. For instance, the ba-
sic concepts of radiation source vis-à-vis radioactive source and irradiation vis-à-
vis contamination are widely confused, as are source safety vis-à-vis source
security.
(14) The concepts, quantities, and units used in radiological protection are also
often misunderstood. Confused communication, mainly caused by the loose use
of terminology, sometimes exacerbated by difficulties in translation, has contrib-
uted to increased public anxiety on this issue. As the report may also be of inter-
est to people other than radiation protection professionals, such as security
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25
2. CHARACTERISING THE SITUATION
2.1.1. Threat
(15) Scenarios for the malicious intent of causing radiation exposure are charac-
terised in terms of their threat. To respond effectively, it is necessary to recognise
and anticipate the type of threat that might trigger such an event. Methodologies
for categorising threats have been developed internationally, for instance, in the
International Handbook on the Physical Protection of Nuclear Materials and Facil-
ities (IAEA, 2002e), but they relate specifically to nuclear materials and facilities
rather than to other radioactive materials or specifically to radiation sources.
However, these methodologies could generally be applied to radiological attacks.
A more important point is that the type and amount of radioactive material
has a greater impact on the response needed, rather than how the source was ob-
tained. This issue is reflected in more generalised emergency planning categorisa-
tion schemes expounded in international requirements (IAEA, 1997b; 2002c,
2003b).
2.1.2. Initiators
(16) It should be recognised that a radiological attack could have many initiators
and that it is impossible to characterise all the possible scenarios. Some conceivable
scenarios are described in Annex A and summarised below.
The simplest setting is one of blackmail, i.e. the threat to use radioactive material
as a weapon, which does not materialise and therefore differs from all other poten-
tial scenarios in that there is no actual radiological impact.
Radioactive material may be stolen, either for a perceived financial benefit (e.g. by
selling it) or as a possible precursor to a malicious attack.
Some conceivable scenarios for a radiological attack are based upon a covert
exposure or dispersal of radioactive material, whereby the first indication that
an event has occurred may be people reporting to hospital(s) with symptoms of
radiation sickness, burns, or other symptoms. Radiation monitors, such as those
used for environmental measurements, could also be the first indicators of a cov-
ert radiological attack.
Radiation sources could also be used to deliberately and maliciously irradiate spe-
cific individuals, a target group, or people at random.
The detonation of conventional explosives to disperse an ordinary radioactive
source (such as those commonly used in medicine and industry) is another
conceivable scenario. This has been dubbed as a Ôdirty bombÕ by the media,
but may be more properly referred to as a radioactive dispersion device
(RDD). An RDD could be made from a source that has been stolen, or with
one that is in situ. Furthermore, the dispersion of radioactive material into the
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(17) As described above, the possible scenarios vary widely in scale, genesis, and like-
lihood but they are rather similar in their ultimate consequence, namely unexpected
situations of uncontrolled public radiation exposure and possible radioactive contami-
nation of the environment. While no single event can be used as a basis for development
of response plans, a number of common features can be recognised as follows.
As the location will probably not be known in advance, planning cannot be spe-
cific. Moreover, as other hazards may be present in addition to the radiation, such
planning should be integrated with other emergency response planning. There-
fore, response plans for dealing with potential emergencies will need to have broad
applicability, as the exact site at which the event may occur and the hazards that
actually exist will not be known in advance.
It is possible that contamination of the immediate area surrounding the attack site
will force the need to restrict access, thus creating response difficulties.
Except for extreme scenarios, the radiation or radioactive material is not likely to
cause immediately fatal consequences, but the psychological perception will be
one of serious danger; moreover, the presence of long-lived radionuclides will cre-
ate prolonged exposure situations.
Early detection of the radiation hazards, and prompt actions to control the spread
of contamination, are critical parts of the response to the attack.
(18) As is the case for radiological accidents, the radiation emergency arising from
a radiological attack will usually occur unexpectedly. The response to protect people,
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ICRP Publication 96
clean up the area, and return to normality would, in principle, be the same for both
situations. However, compared with an emergency at a regulated installation, that
resulting from a radiological attack would present a number of special features.
2.2.1. Location
(19) An emergency resulting from a radiological attack would most likely occur in
a public area where there is no expectation of radiation or radioactive material and
where there may be limited preparedness for responding with radiological protection
measures. The area is most likely to be an urban location, where emergency services
are usually more substantial and concentrated. However, for these locations, the dis-
persion conditions commonly used for emergencies in nuclear facilities may not be
applicable. In this sense, the planning and preparedness are likely to differ from those
usually associated with the radiological scenarios that may result from nuclear
accidents.
(20) The public perception of a radiological attack will be different from that of
some radiological accidents, even if the radiation impacts were objectively similar.
The feeling of the public might be that a radiological attack poses the greater risk.
This in turn may cause public alarm far beyond the normal reaction to the actual
hazards, and it may become increasingly difficult to reassure the public or to manage
the consequences effectively. There will, therefore, be a need to keep the media and
public informed with clear and accurate information, and the mechanism for doing
so needs to be addressed at the planning stage.
(21) The method to deduce the characteristics of the radioactive material is one of
the most important differences between conventional radiological emergency re-
sponse planning and the planning required for responding to RDD and IND events.
In the former, reasonable assumptions can be made about the radioactive material
involved in the situation as the types of sources, facilities, material inventory, etc.
are usually known a priori. In the case of a radiological attack and indeed for chem-
ical and biological attacks, it is very unlikely that there will be any information avail-
able in the early response phase upon which to characterise the source term,
although the range of credible source terms can be anticipated somewhat. Estimates
of source term, however, usually have less practical bearing on the management of
the response than the use of quantified operational criteria established as part of
the planning process and, critically, identifying the radionuclide(s) involved. Precise
information to evaluate a source term will only be known some time after the event
as a result of environmental monitoring, sampling, and analysis conducted through-
out the emergency response (IAEA, 1999b). The degree of certainty about the mag-
nitude of the source term will improve as additional measurement capability
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becomes available. As the results from the measurements are compiled, crude esti-
mates of the source term can be made, working backwards to start estimating
how much radioactive material may have been involved.
(22) An even more difficult situation presents itself when there is a covert radiolog-
ical situation, i.e. the presence of the material is not apparent until someone happens
to measure it or a person presents with a radiation injury. Then the challenge is to
track back from detection to determine where the material is, how much there
was, who else might be involved, and how to make recommendations for protection.
A scenario of particular concern to emergency response planners is an attack involv-
ing chemical, biological, or radioactive material being covertly dispersed in a con-
gested public place, such as a subway system during the rush hour. In a very short
period of time, and long before any one is aware of the situation, small quantities
of material could be all over a large city. Although the quantity of radioactive mate-
rial in any one location would not be at all likely to cause adverse health effects, the
public distress and magnitude of the response might be significant as the forensic
investigation attempted to understand the extent and magnitude of the impacted
areas. While the reaction of the public to a given event has not been fully investi-
gated, the evidence of public reaction to emergencies in the past seems to indicate
that they do not panic, and it appears that the possibility of tremendous panic is
not substantiated by history.
(24) Many law-enforcement agencies, federal agencies, security forces, and emer-
gency services will have intelligence and contingency plans in place to deal with var-
ious types of events. These plans are likely to cater for a wide spectrum of events
including bomb threats, extortion demands, aircraft hijacking, and hostage taking.
It is likely that these plans will have been reviewed and updated in the light of recent
malicious acts.
(25) In cases where a heightened level of threat may exist, e.g. during major events
such as sporting occasions, or in areas that are particularly vulnerable to malicious
acts, such as subway systems, the threat level may justify the installation of instru-
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ments to detect the possible ingress of radioactive material or devices. Such large-
scale deployment of detection devices would be expensive and onerous, so its need
must obviously be commensurate with the level of risk. Another option, possibly less
costly, is to equip security personnel with electronic direct reading of radiation expo-
sure, although this method would not be effective for the detection of alpha-emitters
such as 239Pu.
(26) Furthermore, graded systems for communicating assessments of threat may
be introduced that allow first responders to take additional precautions when
responding to events where a heightened level of threat of radiological attack may
exist in a given area. For example, if a fire emergency at an apparently ordinary
building is suspected to have been caused by a terrorist attack, fire fighters may be
required to monitor the scene for the presence of deliberately introduced radioactive
materials; conversely, if there is no question of a terrorist attack (e.g. because of a
low assessed threat level), fire fighters would not normally monitor the scene. Sys-
tems for communicating threat levels may include generic coding systems at national
or regional level and/or of specific buildings or areas identified as potential targets
and therefore at higher threat levels.
2.2.8. Challenges
2.3. Planning
(31) Current international guidance emphasises the need for all-hazard planning,
where radiological emergency plans are well integrated with arrangements and re-
sources in place for conventional emergencies. The nature of radiological attacks
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(32) Planning for emergencies resulting from a radiological attack, and managing
unexpected disasters in general, share similar concerns. Disasters are typically han-
dled by civil defence operations and these can provide a useful framework for dealing
with a range of emergencies. Dealing with the aftermath of a radiological attack
may, however, differ in some respects from dealing with a radiological emergency
arising from an accident in a regulated facility, due to the difficulty in planning
for random acts that may occur anywhere in a wide range of circumstances. The lo-
cal authorities at a place where a radiological attack occurs may not have an emer-
gency response plan to deal specifically with radiological emergencies, or have any
experience in dealing with such emergencies. Moreover, they may not have immedi-
ate access to radiation detection equipment or other resources necessary to protect
response personnel and the public. It is necessary to develop at least a basic capabil-
ity for such events.
(33) Medical preparedness for a radiological attack is, in many respects, similar to
the preparation needed to respond to other attacks that involve chemical or biolog-
ical materials. The first section of Annex B describes a number of issues related to
medical emergency planning vis-à-vis the various possible threats of radiological at-
tacks. The Commission intends to develop particular guidelines to assist the medical
profession in the preparation for responding to radiological attacks.
(34) If a radiological attack has been threatened, the situation is not unlike the
anticipatory preparations that may be arranged for chemical and biological attacks.
Depending on the planning and arrangements made by local authorities, medical
facilities may receive a notice that some type of threat has been made so that they
can be prepared should the event actually occur.
(35) An important improvement would be for local medical service personnel to be
able to recognise overexposed patients, even if they are not able to deal with their
long-term medical care. In the event that individuals are overexposed, they could
be treated at a specialised regional centre rather than locally. In fact, centres with
specialised burn and haematological units are usually fairly well equipped to handle
radiation overexposure cases. The allocation of scarce resources to develop a local or
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national radiation medical centre to specifically deal with a remote contingency may
not be justified. The medical treatment of patients does not, generally, need to be
hampered by the hazards of the contamination, provided that simple precautions
– not radically different from those normally employed in sterile work – are taken
to reduce the spread of contamination.
(36) One characteristic that will affect medical planning is the fact that the number
of potentially affected people is unknown. Since radiological attacks may occur any-
where, planning should be part of national guidelines for emergency medical services
and hospitals, including smaller, general care facilities (IAEA, 2004c). The guidelines
should ensure that, throughout the country, medical personnel have a user-friendly
reference guide on the basic measures required to deal with the urgent care of poten-
tially overexposed and/or contaminated casualties.
(37) Psychological impacts are likely to pose a significant challenge, and these is-
sues need to be addressed in planning the response to a radiological attack. Follow-
ing a radiological attack, healthcare providersÕ offices, medical clinics, and hospitals
will be deluged with symptomatic and asymptomatic people seeking evaluation, care,
and guidance for possible radiation exposure or contamination. A well-organised,
effective medical response will instil hope and confidence, reduce anxiety, and sup-
port the continuity of basic community functions. Healthcare providers will need
appropriate training in advance, as they may also be subject to fear and anxiety.
Ensuring clear communications and the availability of advance information are
key elements in the successful preparation for managing the consequences of a radio-
logical attack. Advance planning should also recognise the necessity for dealing with
post-traumatic stress, and the concerns that may be engendered for decades follow-
ing the event.
(38) Responding to the mental health needs of the community as a whole raises
many challenges of preparation. In addition to a dedicated area, staffing, contact
registry, and intensified primary care follow-up efforts, intervention for people
concerned with unexplained symptoms should involve brochures, fact sheets,
and literature about self-management approaches to medically unexplained symp-
toms. The use of an on-site advocate who can help people with unexplained
symptoms to overcome perceived barriers to care helps to defuse peopleÕs notions
that Ôno one caresÕ and affords clinicians a way to reduce the pressure to meet
these peopleÕs needs.
2.3.5. Exercises
ment team can quickly generate conjectural recommendations that will find little par-
allelism with what will really happen in practice. The likely reality is that the only
information known is that there was an explosion, that radiation detectors are
alarming, and that the wind is blowing in a given direction, and yet government offi-
cials and news reporters will demand immediate answers to questions, such as should
people evacuate and how far away should they move. The lack of early information
will, in fact, have a significant impact on the extent of what might be recommended
for protective actions. In order to maintain confidence and reduce confusion, it is
considered appropriate to establish a ÔstandardÕ response strategy that is triggered
by key observable parameters and criteria, to train all personnel, including political
decision makers, to implement the plan efficiently and effectively, and then adjust the
details of the strategy as better assessments of the circumstances become available.
Despite the above reservations, the Commission recommends that exercises on plau-
sible scenarios of radiological attacks should be performed, that political decision
makers should participate, and that limited drills should be performed on specific re-
sponse functions to ensure that detailed issues are covered adequately.
2.4. Exposure
2.4.1. Quantification
factors are termed Ôradiation weighting factorsÕ, wR, and Ôtissue weighting factorsÕ,
wT; their values are recommended by the Commission (ICRP, 1991a). The quantities
resulting from the absorbed dose weighting for the effectiveness of the different radi-
ation types and the radiation sensitivity of different organs and tissues are termed
Ôequivalent doseÕ and Ôeffective doseÕ, respectively, and are measured in a unit termed
ÔsievertsÕ (Sv) (in the past, the unit ÔremÕ was used). The equivalent dose is used to
express tissue and organ doses, and the effective dose is used for assessing the whole
body implications. The following scheme provides a visual relation among the rele-
vant quantities, namely: the activity, A; the absorbed dose in a tissue, DT; the equiv-
alent dose in that tissue, HT, that results from weighting the absorbed dose by the
radiation weighting factors, wR; and, finally, the effective dose, E, that results from
weighting the equivalent dose by the tissue weighting factors, wT, and summing up
over all tissues.
(42) It should be noted, however, that the equivalent dose and the effective dose can
only be employed for ÔnormalÕ radiation protection purposes, i.e. for situations caus-
ing relatively low doses that may merely induce low probability and delayed health
effects (stochastic effects). Formally, neither the equivalent dose nor the effective dose
should be used to quantify radiation exposure to the high doses that are able to cause
serious and early pathological effects. Moreover, for radiation with high-LET prop-
erties (such as alpha radiation), the relative biological effectiveness varies depending
upon the type of radiation injury, the organ irradiated, and the time over which the
irradiation is delivered, which will require separate considerations.
(43) An additional difficulty is that radiation detection instruments cannot mea-
sure the dosimetric quantities relating to the human body, such as the equivalent
dose and the effective dose. These can only be estimated from directly measurable
quantities of external exposure, which are termed Ôoperational quantitiesÕ. The oper-
ational quantities are recommended by the International Commission on Radiation
Units and Measurements (ICRU). These have been introduced by the Commission
in Publication 60 (ICRP, 1991a, Paragraph 138), and adopted in international stan-
dards for checking compliance (IAEA, 1996a). There are four operational quantities
of particular interest in the measurement of radiation fields for radiological protec-
tion purposes. These are: the ambient dose equivalent, H*(d); the directional dose
equivalent, H 0 (d); the individual dose equivalent, penetrating, Hp(d); and the individ-
ual dose equivalent, superficial, Hs(d). They are based on the concept of the dose
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equivalent at a point and not on the concept of equivalent dose, and are used for
calibrating measuring instrumentation purposes of radiation protection.
(44) Given the above difficulties, for reasons of simplification and readability, this
report will only use equivalent dose and effective dose to quantify radiation exposure
at both low and high levels. For the same reasons, the report will use a submultiple of
the sievert, termed ÔmillisievertÕ (mSv) as the unit of these quantities, which is equal to
a thousandth of a sievert (1 mSv=100 thousandths of 1 rem or 100 millirem). In order
to put these amounts into perspective, it should be noted that the level of effective
dose that is unavoidably incurred from natural radiation exposure by people living
for 1 year in an area of low background radiation is approximately 1 mSv (the global
average effective dose from natural background radiation is 2.4 mSv/year, and high
background levels are typically approximately 10 mSv/year; in a few areas of the
world, the background levels can be even higher than 100 mSv/year).
2.4.2. Pathways
(45) The potential radiation exposure can vary considerably in magnitude, depend-
ing upon factors such as the particular type and nature of the attack, the total amount
of radioactive material and the different radionuclides involved, the energy with
which they are dispersed into the environment, the nature of the surrounding environ-
ment, and the mechanisms of radionuclide dispersion and transfer. In most cases,
there will be a limited set of exposure routes to consider. When planning protective
actions, it is important to identify the possible exposure pathways and to evaluate
their relative importance. These aspects need to be considered in the development
of response plans, operational criteria, ÔstandardÕ response strategies, and detailed
implementation of protective actions. Different protective actions may need to be
implemented to avoid or reduce the radiation exposure, depending particularly upon
the pathway by which exposure is liable to occur, as well as upon the body organs or
tissues that are likely to be irradiated and the dose that is projected to be received.
(46) People directly involved in a radiological attack will include members of the
public in the affected areas and also rescuers responding to the event. There are two
main mechanisms that may lead to these people being exposed to radiation: external
exposure, that is radiation received from a source outside the body (including radio-
active material deposited on the skin); and internal exposure received from radioac-
tive material that is inhaled, ingested, absorbed through intact skin and wounds, or
introduced into tissues as fragments which are either radioactive or contain radioac-
tive contamination. The overall risk to the individual person represents the summa-
tion of effects of external and internal exposures.
(47) Pathways of external radiation exposure include:
directly from the source or facility;
contamination of skin and clothing;
the plume of dispersed radioactive material;
residual contamination on the environment, buildings, vehicles etc.; and
contaminated consumer products and other commodities.
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(50) Initial reaction to a radiological attack will depend upon the initiating
event, e.g. whether it is an explosion or, in extreme cases, an IND. Following
the first response, there will be a number of evolving response phases and different
types of interventions involving specific protective actions, such as: control of ac-
cess to the public; sheltering; evacuation; administration of prophylactic measures;
decontamination of people, land and property; relocation; control of water, foods
and other commodities of public consumption; livestock and animal protection;
waste management and control; refinement of access control; release of personal
property, land and buildings; re-entry of non-emergency workforce; and re-inhab-
itation of homes. Some of these protective actions will be discussed in detail in
Chapter 5.
(51) Many of the postulated scenarios are for some type of explosive initiating event,
which in fact are the easier events to respond to because the initiation is obvious. Many
countries equip first responders, such as fire fighters, with some type of radiation
detection capability onboard their vehicles. These first responders will usually react
in the same way as they would for any other type of explosion and situations poten-
tially involving hazardous material, namely establishing a perimeter for access con-
trol, taking life-saving measures, and aiming to control the situation. For most
types of situations, the standoff distance that fire brigades typically establish when
responding to an explosion is also adequate when radioactive material is involved.
When the results from radiological surveys are available, the perimeter can be adjusted
as needed.
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(54) The response to an emergency, including those that involve a radiological at-
tack, will generally take place in three distinct phases, namely rescue, recovery, and
restoration (some emergency planners use the terms ÔearlyÕ, ÔintermediateÕ, and Ôlong
termÕ in describing these phases of response). Their characteristics will be briefly de-
scribed hereinafter. The recommended protective actions and guidelines will be ad-
dressed in the following chapters.
(55) The rescue phase must recognise that the immediate aftermath of an incident
is likely to be chaotic, and the emergency servicesÕ initial efforts must focus on bring-
ing the scene under a measure of control, which will allow rescue efforts to proceed in
an orderly manner. The priority actions are to save life and to evacuate injured peo-
ple, which may proceed under hazardous and high-risk conditions. The lead agency
at this stage is likely to be the local fire service, which is best equipped and experi-
enced to manage rescue operations, aided by other emergency services. However,
other agencies, such as law enforcement, will also be present and need to be inte-
grated into the management structure.
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2.6.2. Recovery
(56) The recovery phase is geared towards stabilising the scene and ensuring that
all immediate hazards are removed or reduced to a low-risk level. During this phase,
local and national officials will initiate the scene-of-crime examination and will seize
all relevant material that may be required for evidential and forensic purposes. Also
during this phase, the control of the scene may be shared between recovery personnel
and law-enforcement officers. In this phase, first decisions might be made on reloca-
tion, and food and water controls.
2.6.3. Restoration
(57) In the restoration phase, there is a gradual restoration of the site to normal
operations, and the emergency management system, which managed the rescue
and recovery phases, will hand control of the scene to the authorities responsible
for determining the restoration objectives and the process used to remove remaining
hazards to agreed levels.
2.7. Links
(58) The relationship between exposure routes, protective actions, and response
phases varies depending on the unique circumstances of the specific radiological at-
tack. In Table 2.1, which is of a qualitative rather than quantitative nature, an
attempt is made to identify some of the potential scenarios and links to be expected
at various phases during the response. As can be seen, there will be an overlap be-
tween the different phases and the protective actions that may be taken.
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Table 2.1 Emergency phases, exposure routes, and protective actions following a malicious attack ( )
ACTIONS
Evacuation
Sheltering
Control of access to the public
Administration of prophylactics
Decontamination of people
Decontamination of land and property
Relocation
Food controls
Water controls
Livestock and animal protection
Waste control
Refinement of access control
Release of personal property
Release of land and buildings
Re-entry of non-emergency workforce
Re-entry to homes
41
3. POTENTIAL HEALTH EFFECTS ATTRIBUTABLE TO RADIATION
EXPOSURE
(59) Following radiation exposure, all resulting biological health effects will
generally be attributable to the induction of damage to cells in the tissues and
organs of the body. Of the various types of radiation-induced damage to cellular
components, the most important is that occurring in DNA which acts to genet-
ically control all aspects of cellular function. Much of this radiation-induced
DNA damage can be repaired by cellular systems. Correctly repaired damage will
have no consequences, but unrepaired or incorrectly repaired damage may kill the
cell, prevent its reproduction, or result in a viable but genetically modified (mu-
tated) cell.
(60) If enough cells in an organ or tissue are killed or severely damaged, there will
be clinically detectable injury and reduction or loss of tissue or organ functions. This
type of effect is termed ÔdeterministicÕ by the Commission. These effects are observed
in individuals as tissue injuries if the radiation dose is above a level (the dose thresh-
old) that results in the killing or malfunction of sufficient cells. Above the dose
threshold, the severity of these effects, including impairment of the capacity for tissue
recovery, increases with dose.
(61) Few tissues show clinically significant deterministic effects following acute
equivalent doses of less than 2000–3000 mSv of low-LET radiation such as gamma
and beta radiation. For doses spread over a period of months and years, severe ef-
fects are not likely in most tissues at annual equivalent doses of less than about
500 mSv. However, the gonads, the lens of the eye, and the bone marrow show some-
what higher sensitivities. The most important tissues to consider for clinical purposes
following whole body irradiation are skin, bone marrow, the gastrointestinal tract,
lymphatic tissue, and lung. Other tissues may be relevant for circumstances involving
internal contamination by specific radionuclides.
(62) Differences in the structure and radiosensitivity of different tissues are re-
flected in the clinical manifestation, or syndromes, of radiation effects. The second
section of Annex B (see also Chapter 6) presents relevant information for the
immediate medical prognosis and treatment of the radiation effects that may arise
from a radiological attack that principally involves whole body exposure. This in-
cludes: the prodromal phase of acute radiation syndrome; the change of lympho-
cyte counts in the initial days of acute radiation syndrome depending on the
dose of acute whole body exposure; the latent phase of acute radiation syndrome;
the findings of the critical phase of acute radiation syndrome following whole body
exposure; the principal therapeutic measures for acute radiation syndrome accord-
ing to degree; and the time of onset of clinical signs of skin injury depending on
the dose received.
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ICRP Publication 96
(67) In Publication 82 (ICRP, 1999), the Commission noted that prenatal exposure
should not require specific levels of protection in prolonged exposure situations
where the annual dose is well below about 100 mSv, such as those to be expected
from most radiological attacks with RDDs. This is inter alia because: (i) there is a
very low probability of excess childhood cancer including leukaemia in the liveborn
as a result of in-utero irradiation; (ii) no organ malformations or neurological effects
should be expected at these fetal dose rates.
(70) Health effects following an IND event present some special characteristics as
far as the health consequences are concerned. The extreme blast and thermal effects
will significantly amplify the health treatment issues, and necessitate triage to place
resources where they can be useful. This will be exacerbated by the likely loss of most
or all infrastructure capability to deal with health issues in the immediate vicinity of
the detonation. For those who survive an attack, the presence of fission neutrons
must be considered in addition to the gamma radiation and contamination. It has
long been recognised that fission neutrons have greater biological effectiveness than
gamma rays. In Publication 60, the Commission recommended the use of energy-
dependent radiation weighting factors for cancer risk based upon incident neutron
energy (ICRP, 1991a).
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ICRP Publication 96
(71) Table 3.1 provides a simplified summary of the expected health consequences
of the exposure of people to whole body irradiation. The health effects from partial
body irradiations of >1000 mSv would need to be assessed on a case-by-case basis,
involving expert input.
(72) Any type of terrorist attack will create uncertainty and fear. The possibility of
radiation exposure resulting from a radiological attack will add to the stresses asso-
ciated with physical trauma, forced dislocation, uncertainty about safety, loss of
homes, jobs, friends, pets, and other factors. Fundamental questions that are unique
to a radiological attack which must be addressed include: Am I and my family safe?
Was I exposed? How much radiation did I get? Am I still contaminated? How will
this affect me, my family, etc.? What will happen next? The acute and delayed psy-
chological and behavioural effects, including stigmatisation, are likely to be at least
as important and challenging as radiation-related biological injuries and illnesses.
The fear and pre-occupation surrounding the radiation exposure and the possibility
of cancer would probably remain high for decades. This may also result in the mis-
attribution of any illness to radiation exposure. Clear, understandable, and empa-
thetic communications are needed, both immediately following the event, and
repeatedly and consistently for extended periods of time after the event.
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3.2.1. Distress
(75) Following a radiological attack, fears about and pre-occupation with cancer
and other health effects attributable to radiation will be a significant psychological
effect and can remain high for years. Responding honestly and acknowledging what
is not known is important. Healthcare providers should understand the basics of the
health consequences of radiation and be trained so as to be ready to explain them to
people in a straightforward manner. Uncertainty about health effects should be
acknowledged and not minimised in communicating to the public (see Chapter 7).
It is of great importance to give all possible information in a transparent way. These
actions should help to avoid misattribution of illness.
47
4. PROTECTING RESPONDERS
(76) Following a radiological attack, one of the early radiological protection issues
is to protect the first responders. These will be the police, fire fighters, paramedics,
and other support and intervention services personnel. They may have to exercise
their duties with little knowledge of the actual hazards present, and may need to
use an all-hazards approach and assume that biological, chemical, and radiological
hazards may be present. As a result, it is necessary to have criteria as well as methods
for radiation protection of first responders and rescuers who will respond to an event
(IAEA, 1997c; 2002d). It is to be noted that while these recommendations deal with
radiological hazards and protection, the first responders may need additional protec-
tion as a result of the other potential hazards.
(77) In most situations, the radiation dose is likely to be due to external exposure,
inhalation in the plume for a fire or explosion, or inadvertent ingestion. The initial
radiation protection of first responders can be accomplished, in most cases, without
monitoring, by taking some basic precautions that also apply when responding to
emergencies involving other types of hazardous material. These involve restricting
the proximity to, and limiting time near, suspicious objects, avoiding inadvertent
ingestion, using respiratory protection, and staying out of smoke. If a radiological
hazard is suspected, as far as feasible, provisions should be made to provide the first
responders with alarming dosimeters with preset levels based on predefined criteria
that take likely exposure pathways and protective measures into account. The first
responders should have received basic guidance on how to recognise a potential
radiological emergency, the initial actions to take, and how to obtain timely radio-
logical assessment support, and should be provided with some basic radiation mon-
itoring equipment.
(78) Specialised emergency workers will probably arrive at the scene of a radiolog-
ical attack after the first responders. Included among these workers should be a radi-
ation protection specialist who will be able to begin characterising the radiological
hazards present and provide guidance and advice to on-scene emergency response
officials. The assessment and control of their radiation doses are thus usually ame-
nable to more detailed planning.
(79) Both first responders and specialised emergency workers should be subject to
occupational exposure guidelines tailored to the situation rather than to any categor-
isation of the workers. In international occupational radiation protection standards,
the areas of work rather than the workers themselves are categorised.
be volunteers and should be instructed in dealing with radiation hazards to allow them to make informed
decisions. Female workers who may be pregnant or nursing should not participate in these operations.
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ICRP Publication 96
to be aware of the possibility, especially if the variable ÔtimeÕ is used to manage the
doses to first responders.
(90) The skin should be protected to reduce potential burns from high levels of rel-
atively non-penetrating beta radiation, and to prevent possible transfer of radioac-
tive material into the body through the skin and inadvertently through the mouth
or nose. The choice of clothing will often be influenced by more immediate hazards
such as fire, heat, or chemicals. Protection against these other hazards will generally
provide protection from radioactive material. For medical personnel, normal barrier
clothing and gloves may provide personal protection against intake of contamina-
tion. Disposable medical scrub suits, high-density polyethylene or other close-weave
coveralls, and hoods should be used if available. Secondary contamination of the
medical staff from handling patients should not be a cause of great concern; however,
to prevent the unnecessary spread of contamination and thereby reducing the need
for clean up, it is prudent to utilise conventional protective clothing.
(91) Some countries have specific guidance covering the use of respiratory protec-
tion (USACHPPM, 2003). In most situations, respiratory protection that is designed
to protect responders against chemical or biological agents is likely to offer some de-
gree of respiratory protection in a radiological attack. Concerns about the presence
of chemical or biological contaminants will influence the selection of respiratory pro-
tection. If used properly, simple facemasks provide reasonably good protection
against inhaling particulates, and allow sufficient air transfer for working at high
breathing rates. If available, high-efficiency particulate air filter masks provide even
better protection. Greater hazards must always be considered when selecting breath-
ing protection.
53
5. PROTECTING THE PUBLIC
(92) Activities to provide protection for members of the public following a radio-
logical attack may be divided into a number of actions, corresponding to the phases
of responding to the event as described in Chapter 2. These actions are grouped
according to whether they are required immediately, urgently following the immedi-
ate actions, more gradually based on the results of surveys and dose assessment, or
during the later aspects of the recovery and restoration phases. The CommissionÕs
fundamental principles of justification of the intervention and optimisation of the
protective actions have to be taken into account on a case-by-case basis. The Com-
mission has provided recommendations for the application of the optimisation prin-
ciple (IAEA, 1986; ICRP, 1973, 1983, 1989) and is working on a new publication on
this subject.
(95) Difficulties associated with controlling access to large areas mainly comprise
difficulties of enforcement following prolonged implementation of this protective ac-
tion when people may be anxious to return to their homes. While control of access
may only be required as a short-term measure, long-term limitation of access may
result in significant impacts, including the deterioration of the infrastructure within
the area, and these decisions should be considered as part of a relocation as described
later. While it is not possible to give intervention levels of dose for this protective
action, operational criteria are needed that should, to the extent possible, be based
on advance planning that takes account of justification of the intervention and opti-
misation of protection, practical matters, and decisions about other long-term pro-
tective actions, such as relocation, and remedial measures, such as decontamination.
Separate consideration will be needed for control of access in the immediate area of
the event and more widely affected areas.
(96) The spread of radioactive contamination may be an important issue associ-
ated with a number of possible radiological attack scenarios. This spread of contam-
ination may occur through water runoff from fire-fighting activities, smoke from
burning debris, or transit of vehicles or personnel through a contaminated area prior
to control being established. In certain situations, extinguishing a fire may be more
hazardous than leaving it to burn (e.g., fire on a gasoline tanker or fire involving
water-reactant chemicals). This decision is difficult and will require careful assess-
ment of site-specific conditions and potential fire exposures. Normal fire fighting
and hazardous material response doctrine would generally prevail and the conse-
quences of the actions would be mitigated later.
(99) It is important to quickly triage those who have various levels of radiation
exposure into distinct groups, as follows:
those unlikely to survive as a result of high external exposure and who require pal-
liative care;
those who are likely to suffer acute radiation syndrome as a result of external
exposure and will require hospitalisation;
those with doses in excess of several hundred mSv but who do not require special
medical care;
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ICRP Publication 96
not received significant exposure, but who exhibit high anxiety over their condi-
tion and their future prognosis. Finally, there will be concerns for family mem-
bers, pets, etc. that will need to be handled. Mental health professionals
including psychiatrists should be an integral part of the pretrained teams that per-
form initial screening and triage.
(104) Radioactive material may have been deposited on or in the person. Skin or
wound contamination is never immediately life threatening to affected people or
medical personnel. Therefore, treating conventional trauma injuries is the first prior-
ity. People should be decontaminated only after medical stabilisation. Evacuation of
a group of people should not be delayed by action to decontaminate individuals.
Note should be made that if certain chemical agents are present, it may be necessary
to decontaminate people immediately at the site and this will take priority over deal-
ing with radioactive contamination.
(105) There is no generic intervention level for the protective action of personal
decontamination, but common sense dictates that attention is directed at those indi-
viduals who have been in the most heavily contaminated areas following the event. If
extremely high levels of skin contamination have occurred, specific decontamination
agents may have to be used under medical and health physics supervision. In situa-
tions where immediate medical attention or evacuation is not warranted, emergency
medical service personnel may have the opportunity to decontaminate people at the
scene of an event. As this will not always occur, decontamination procedures should
be part of the operational plans and procedures of all healthcare facilities.
(106) On the whole, surface radioactive contamination can be significantly reduced
by removal of the contaminated clothing. Most remaining contamination will be on
exposed skin and hair, and it may be effectively removed with soap, warm water, and
a washcloth. Skin scrubbing is not recommended, as it would unnecessarily damage
the skin which facilitates incorporation of radioactive material. Clothing can be
stored in plastic bags for checking later when advice can be given on washing or
disposal.
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5.2.2. Sheltering
(109) Except within the potential explosive blast zone, from which people are
likely to be evacuated, advice from authorities that individuals should stay or go in-
doors (wherever they are), an action usually termed ÔshelteringÕ, may provide a sub-
stantial reduction in their possible exposure. The actual reduction depends upon the
type and construction of the buildings available for sheltering. For example, the dose
averted can increase by up to a factor of 10 or even more if cellars are included. If
windows and doors are closed and any ventilation systems turned off, movement of
particles into the building will be minimised and subsequent doses from inhalation of
radionuclides and skin contamination can also be reduced. After it has been con-
firmed that the plume of radioactivity has passed, it may be advisable to open win-
dows and turn on ventilation systems to reduce doses by diluting the concentration
of any radionuclides that may have entered the building. However, there is some risk
that this will distribute the materials that may be present on the filters or ventilation
into an otherwise unaffected building. Other complicating factors such as resuspen-
sion due to vehicle movement must also be considered.
(110) Sheltering may be a very effective protective action early in the event,
depending upon the type of building available and its location with respect to the site
and type of the event. There is, however, a need to have a rapid and effective means
of communicating with the people who are advised to shelter. Typically, there will be
priority arrangements for the emergency management to provide information on
public radio and television. The disadvantages of sheltering are low if individuals
are in their own homes, and if it is recommended for relatively short periods of time
(i.e., hours). There will be relatively little effort involved in short-term and localised
sheltering, except where important societal activities are disrupted and there are eco-
nomical losses. Sheltering for longer periods can cause social and economic problems
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and lead to increased anxiety. There are also problems with sheltering if recom-
mended when members of a family are in different locations, i.e., home, work, and
school.
(111) In the longer term, after passage of the radioactive plume arising from the
event, sheltering continues to avert external radiation dose from ground deposits of
radionuclides. An averted dose factor of at least a few and up to some tens might be
expected, depending upon the type of structure. However, for longer periods of time,
this interferes with normal living and may cause distress, although anxiety may be alle-
viated by advising people that short periods of time spent outdoors for necessary activ-
ities will not, in many situations, result in very high exposures. The advantages and
disadvantages of such a part-time sheltering strategy should be assessed when justify-
ing and optimising the intervention level in advance at the planning stage.
(112) Analyses for justifying the undertaking of sheltering and optimising the con-
ditions should include consideration of damage imposed to individuals and society
(e.g., losses to industry, trade, and agriculture) and doses incurred by those respon-
sible for implementing the intervention (e.g., police). In the justification and optimi-
sation analyses, it may also be appropriate to give separate consideration to
identified groups within the population, in addition to the exposed population as
a whole. Such groups, which should be reasonably well defined and can include ur-
ban and rural populations, pregnant women, small children, sick or handicapped
people, and outdoor workers, may present substantive differences in the sheltering
costs, in their potential for averting doses, and in other factors.
(113) On a generic basis, the Commission estimates that sheltering will almost al-
ways be justified provided that an averted effective dose of 50 mSv can be achieved
during the time considered feasible for sheltering (ICRP, 1991b). Optimised levels
will be lower but not by more than a factor of 10 when consideration is given to spe-
cific emergency conditions and subgroups of the population. As sheltering for the
short term is such a low-risk countermeasure, it is more likely to be implemented
to avert the lowest levels of dose. It reduces exposure during the period when fuller
assessment is made of the dose consequences and thus the action required. The BSS
report that if sheltering cannot avert more than 10 mSv in a period of about 2 days,
the benefit is questionable. The Commission considers this to be a relevant figure for
planning sheltering actions in the event of a radiological attack.
(114) When a decision is made to shelter a population, those members of the pub-
lic who are able to return home should be advised to shower and change clothes as a
simple precaution against any external contamination. Clothes may need to be seg-
regated in normal plastic waste bags and, following indication from the authorities,
could be laundered normally, although it may be advisable to wash them separately
from other clothes to avoid cross-contamination. This is a recommended action as
there is no harm and a potential benefit is associated with it.
5.2.3. Evacuation
portation to the new location and back, the additional costs of living (shelter, food,
general medical care, schools, etc.) in the provisional location, compensation for loss
of income and inconvenience, and the costs of surveillance of property left behind.
(120) On a generic basis, the Commission estimates that evacuation is almost al-
ways justified if the projected average individual dose to the whole body is likely
to exceed 500 mSv within 1 day, or the averted average individual effective dose
for the duration of the evacuation is 500 mSv or the averted equivalent dose to
the skin is 5000 mSv. It is expected that, for most foreseeable accident situations,
an optimised level of averted effective dose for evacuation will be lower but not by
more than a factor of 10. The BSS conclude that the generic optimised intervention
level for evacuation is 50 mSv of avertable dose in 1 week, i.e., approximately
100 mSv in 2 weeks. The Commission concurs with this international requirement
and also advises the use of 500 mSv of skin equivalent dose in radiological attacks.
(121) Evacuation is a short-term protective action and its continuation must be
justified by a continuing hazard. This might be the failure to control the source of
the release, a significant risk of a further accident or release, or a persistence of ele-
vated radiation dose rate in the environment. However, beyond a few weeks, this
should be considered as temporary relocation, and justified and optimised
accordingly.
(128) More refined estimates of doses to members of the public should be made
during the recovery phase. The first results of environmental monitoring may be
available, leading to identification of the source term for the release, as well as
the first predictions of the extent of the affected area and a forecast of the future
potential progression (IAEA, 1999b). Moreover, very approximate external doses
may be estimated initially from clinical signs such as nausea and erythema. These
people should be hospitalised. Depending upon these dose assessments and predic-
tions, some people who have been sheltered may be allowed to move; alternatively,
a decision may be made that those who have been sheltered need to be evacuated.
Gradually, a more refined biological dose assessment could follow, including blood
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cell counts and biological dosimetry (see below). This is valuable for informing the
public about what has happened, what is likely to happen, and what further ac-
tions are planned.
(129) In the recovery phase from a major event, there is a public health require-
ment for counselling individuals on the longer-term implications of their exposure,
principally cancer risk. An estimate of the dose received by an individual will greatly
facilitate the advice that can be given. There are three principal methods for assessing
doses by biological measures: changes of the haematological parameters (blood cell
counts, especially lymphocytes); cytogenetic changes; and radicals induced by radia-
tion in bone and teeth, measured by electron spin resonance (ESR). It should be
noted that these methods can only be used for a limited period of time after the expo-
sure. Criteria for using such methods need to be determined at the planning stage,
particularly as the use of such methods will depend on their availability.
(130) Lymphocytes in peripheral blood will decrease significantly within days after
exposure to radiation doses of 1000 mSv and higher (whole body or large parts of the
body). The extent of this effect and the time course is dose dependent. After higher
whole body doses (>3000 mSv), the number of granulocytes and (later) thrombo-
cytes and erythrocytes will also decrease. From these changes of blood cell counts,
rough dose estimates can be obtained.
(131) More accurate estimates of the dose to the whole body or large parts of the
body in lower dose ranges can be obtained by cytogenetic measurements. After sig-
nificant radiation exposures, chromosomal aberrations become visible, with the for-
mation of dicentric chromosomes being particularly important for dose estimation.
In recent years, chromosomal translocations have also been measured by the fluores-
cence in-situ hybridisation technique. In specialised laboratories, it is possible to esti-
mate doses in the range of approximately 100 mSv and higher from chromosomal
aberration studies in peripheral blood lymphocytes. The technique needs good exper-
tise and is laborious; it takes approximately 1 week to obtain results. Only a few indi-
viduals can be analysed at a time. An easier technique is the determination of
chromosomal aberrations by measuring micronuclei in lymphocytes; this method
is less sensitive and laborious, quicker, and a higher number of individuals can be
studied. There are few laboratories in the world experienced in these techniques,
therefore international co-operation is necessary.
(132) After radiation exposure, radicals are formed in the exposed material. They
disappear quickly in soft tissues, but remain in bone and teeth for a longer period of
time. With the ESR method, these radicals can be measured and doses can be esti-
mated in ranges of several hundred mSv and higher. It is also possible to measure
these radicals in solid materials such as bricks and use such studies for dose estima-
tion. Again, there are only a few specialised laboratories with this capability, which
means that the cytogenetic and ESR methods are not practicable if dose estimates
are needed for more than a few hundred people.
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(133) Relocation is distinguished from evacuation mainly by the time over which
this action is taken. It refers to the long-term removal of people from an affected
area. It may be undertaken as an extension to evacuation or it may be introduced
weeks or months after an event has occurred to reduce doses from deposited radio-
nuclides and to allow remedial measures to be carried out. The duration of reloca-
tion may be permanent (usually termed ÔresettlementÕ) or may be for a more
limited period (usually termed Ôtemporary relocationÕ). This will depend upon the
decline in the dose rate (due to radioactive decay, weathering processes, and any
remedial action) and social factors (e.g., provisions for rehabilitation of the affected
area).
(134) The risks and difficulties associated with temporary relocation and resettle-
ment are different from those for evacuation. Although these countermeasures are
usually urgent and movement of population groups can be carefully planned in ad-
vance and controlled in implementation, financial costs may be high and will depend
upon the numbers of people involved and the loss of production in the affected area.
In addition, the social costs of disruption and anxiety will also be substantial. Once
people have been informed that their temporary relocation or resettlement is desir-
able, they will be concerned and understandably anxious. The competent authorities
will need to keep them well informed, to explain the risks, and to proceed with the
relocation without undue delay.
(135) The efficiency of temporary relocation and resettlement in averting average
individual doses, both internal and external, in relation to time should be estimated
based on environmental measurements and modelling. In justifying and optimising
the intervention level, the entire population to be relocated should be considered
with the distribution of averted doses and corresponding costs. Several costs need
to be considered when examining the impact of these countermeasures. These in-
clude: transport costs; the costs of providing new housing, schools, medical care,
and workplaces; any extra food costs; and compensation for lost income, property,
industrial investment, agricultural capital, and health effects associated directly with
relocation itself and associated stress.
(136) Resettlement may cause different social problems that should be considered
in the final decision-making. In order to treat the various factors contributing to the
final decision in a systematic and rational manner, several decision-aiding techniques
can be used. Decision conferences seem to offer a good option to systematically han-
dle complex issues involving socio-economic and political factors together with
radiological and other health problems.
(137) From generic considerations, an average averted effective dose level of about
1000 mSv is almost always justified for relocation. Depending on the circumstances,
relocation may be justified at lower levels of averted dose, but after a very severe inci-
dent, the justified level of averted dose for relocation may be even higher than this
reference level. In Publication 63 (ICRP, 1991b), the Commission estimated the dose
rate from deposited activity above which relocation is optimised at about 10 mSv/
month for continuing and prolonged exposure.
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5.4.1. Clean up
(138) The restoration phase is the period when remediation and clean-up actions
designed to reduce radiation levels in the environment to acceptable levels are com-
menced, and it ends when all the remediation actions, including the management of
the radioactive wastes and residues originated in the operations, have been com-
pleted. With the additional time and increased understanding of the situation, there
will be opportunities to involve interested parties in providing sound, cost-effective
recommendations. While the Commission has provided many recommendations
on the use of formal techniques for optimisation of protection (ICRP, 1973, 1983,
1989), the involvement of interested parties may broaden the practical application
of optimisation in the decision-aiding process that should lead to a wider decision-
making process. Generally, early (or rescue) phase decisions will be made directly
by elected public officials, or their designees, with limited interested parties involve-
ment of other parties due to the need to act within a short time frame. Long-term
decisions should be made with stakeholder involvement, and can also include tech-
nical working groups to provide expert advice to decision makers on impacts, costs,
and alternatives.
(139) Clean-up planning and discussions should begin as soon as practicable after
an attack to allow for selection of interested parties and subject matter experts, plan-
ning, analyses, contractual processes, and clean-up activities. National authorities
may choose to predetermine interested parties, and consideration should be given
to discussing and agreeing endpoints for the clean-up activities, as this can make
the withdrawal of intervention measures more acceptable to the public. These activ-
ities should proceed in parallel with ongoing recovery phase activities, and co-ordi-
nation between these sets of activities should be maintained. Preliminary remediation
activities carried out during the recovery phase, such as decontamination, resump-
tion of basic infrastructure function, and some return to normality in accordance
with recovery phase guidelines, should not be delayed for the final site remediation
decision.
(140) Optimisation of protection should be applied to clean-up decisions, as a flex-
ible process in which numerous factors are considered to achieve an end result that
balances local needs and desires, health risks, costs, technical feasibility, and other
factors (IAEA, 1997a). The general process provides decision makers with input
from national technical experts and stakeholder representatives, as well as providing
an opportunity for public comment. The extent and complexity of the clean-up pro-
cess following an attack should be tailored to its specific needs.
(141) Features of the optimisation process for clean up are as follows:
Transparency – the basis for clean-up decisions should be available to interested
parties representatives and, ultimately, to the public at large.
Inclusiveness – representative interested parties should be involved in decision-
making activities.
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type of waste. The Commission also notes that a number of countries have under-
taken legally binding commitments through the international Joint Convention on
the Safety of Spent Fuel Management and the Safety of Radioactive Waste
Management.
(145) If full decontamination is not feasible after a radiological attack, the long-
term aftermath can result in a situation of prolonged exposure caused by the remain-
ing radioactive residues. Publication 82 (ICRP, 1999) addresses the application of the
CommissionÕs system of radiological protection to controllable radiation exposure
due to long-lived radioactive residues such as those that may remain after a radio-
logical attack.
(146) The Commission recommends the use of generic reference levels for interven-
tion in these situations, which are conveniently expressed in terms of the existing an-
nual dose. It is noted, however, that these levels should be used with extreme caution.
If some controllable components of the existing annual dose are clearly dominant,
the use of the generic reference levels should not prevent protective actions from
being taken to reduce these dominant components. The use of the generic reference
levels should not encourage a Ôtrade-offÕ of protective actions among the various
components of the existing annual dose.
(147) A low level of existing annual dose does not necessarily imply that protective
actions should not be applied to any of its components; conversely, a high level of
existing annual dose does not necessarily require intervention. With these provisos,
an existing annual dose below about 10 mSv may be used as a generic reference level
below which intervention is not likely to be justifiable for some situations. Below this
level, protective actions to reduce a dominant component of the existing annual dose
are still optional and might be justifiable. This is illustrated in Fig. 5.1. In such cases,
Fig. 5.1. Describing the need for intervention in prolonged exposure situations.
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(149) The protective actions required in the aftermath of a radiological attack will
generally be disruptive and restrictive of the ÔnormalÕ living conditions of people.
Eventually, in order to return to ÔnormalityÕ, such actions will need to be discontin-
ued at some stage, although, in some situations, the background radiation levels may
be higher than before the event as a result of residual contamination that may be dif-
ficult or impossible to remove. The simplest basis for justifying the discontinuation
of protective actions is to confirm that the exposures have decreased to below the
action levels that would have prompted the authorities to intervene. If such a reduc-
tion in exposure is not feasible, the generic reference level of existing annual dose be-
low which intervention is not likely to be justifiable could provide a basis for
discontinuing intervention.
(150) In practice, the exposed population may find it difficult to accept that pro-
tective actions should be stopped, and the social pressures may override the benefit
of discontinuing the intervention. In these cases, the participation of the stakeholders
in the decision-making process becomes essential and, as mentioned in Paragraph
139, it may be advisable to discuss and agree the endpoints at the outset of the
clean-up activities. After intervention has been discontinued, the remaining existing
annual dose should not influence the normal living conditions in the affected area,
including decisions about the introduction of new practices involving radiation expo-
sures, even if such a dose is higher than that prevailing in the area before the event.
(154) It should, however, be noted that the numerical dosimetric guidance pro-
vided in these tables cannot be used directly since the quantities will not usually
be directly measurable. The guidance can be used as a basis for the development
of operational intervention levels (OILs), which are expressed in quantities that
are directly measurable, and should be developed at the planning stage.
(155) OILs should be developed in advance for determining when exposure rates
or contamination levels warrant taking protective action and other countermeasures
in the event of a radiological emergency (IAEA, 2002c). Actions for which the devel-
opment of OILs may be required include: control of access and isolation of a
Table 5.2. Recommended generic criteria for intervention in prolonged exposure situations (Source: ICRP
1999, Fig. 6)
Intervention Criteria (existing annual
effective dose in mSv/year)
Almost always justifiable )100
May be justifiable J 10
Unlikely to be justifiable [10
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(156) Consumer goods, such as water, food, and other commodities of public
consumption, can be contaminated with radioactive materials, either as a deliber-
ate act or as a consequence of another type of radiological attack. For instance,
the ÔfalloutÕ from a plume of dispersed radioactive material could contaminate all
types of commodities, possibly at significant distances from the dispersal point,
depending on the dispersal method (e.g., detonation of an RDD). These situations
are unlikely to lead to the significant internal contamination of a large number of
people due to the large amounts of radioactive material that would be required to
reach high levels of contamination in mass-produced or distributed supplies.
However, past experience seems to show that the public concern generated by
such an act could present a significant challenge to the authorities. Although it
is unlikely (although not impossible) that there would be a need for emergency
monitoring of a large number of people for internal contamination, there is a
need to co-operate with radiological experts and media specialists to quickly as-
sess the potential medical impact of such acts and provide public information
to alleviate fears in the potentially affected public (IAEA, 1999b). There is also
a need to develop a plan, at national level, to monitor a representative sample
of the potentially affected population to confirm the health risk assessment and
reassure the public.
(159) Notwithstanding the above, the Commission welcomes the recent intergov-
ernmental international consensus on radiological criteria for radionuclides in com-
modities (IAEA, 2004b; 2004d). National authorities may wish to consider such a
consensus in deciding control measures on commodities that could be contaminated
as a consequence of a radiological attack.
(161) In relation to foods, following the Chernobyl accident, the Codex Alimentar-
ius Commission (CAC) adopted generic intervention exemption levels for radionuc-
lides in foodstuffs following a nuclear accident (Codex Alimentarius, 1991). These
levels, which are currently incorporated into the BSS, have been revised recently
by the CACÕs Committee on Food Additives and Contaminants (CFAC) (Codex
Alimentarius, 2004). The CAC is expected to review and formally adopt these levels
in the near future. While the Commission considers that the revised levels for 238Pu,
239
Pu, 240Pu, and 241Am are relatively conservative, it recommends that the levels fi-
nally adopted by the CAC should be applied to manage the distribution of foodstuffs
that could be contaminated as a result of a radiological attack in an internationally
coherent and consistent manner, particularly if international trade is involved. The
CFACÕs revised levels are given in Table 5.5.
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Table 5.5. Committee on Food Additives and ContaminantsÕ revised guideline levels for radionuclides in
foods
Radionuclides in foods Guideline level
(Bq/kg)
238
Pu, 239Pu, 240Pu, 241Am 1
90
Sr,106Ru,129I,131I, 235U 100
35 60
S, Co, 89Sr, 103Ru, 134Cs, 137
Cs, 144
Ce, 192
Ir 1000
3 * 14
H , C, 99Tc 10,000
* This represents the most conservative value for tritium (organically bound).
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(162) In relation to water supplies, the Commission notes that the World Health
Organisation (WHO) has developed specific guidance levels for radionuclides in
drinking water (WHO, 2004). Again, while the Commission considers that some
of these levels are conservative, it recommends that they should be applied to man-
age the supply of contaminated water following a radiological attack. The WHO lev-
els are given in Table 5.6.
(164) If the annual doses in the area affected by the event are acceptable because
the intervention strategy has been optimised, the situation outside the affected area
should also be acceptable because the individual annual doses elsewhere from the use
of commodities produced in the affected area would normally not be higher than
those in the affected area. If the restrictions on commodities produced in the area
affected by the event have not been lifted, production of the restricted commodities
should not be restarted; conversely, if the restrictions have been lifted, production
can be restarted. If an increase in production is proposed, it could proceed subject
to appropriate justification. In circumstances where restrictions have been lifted as
part of a decision to return to ÔnormalÕ living, the resumption and potential increase
of production in the affected area should have been considered as part of that deci-
sion and should not require further consideration.
(165) In some scenarios, it can be imagined that radioactive residues may become
very sparsely distributed in the environment, usually as Ôhot particlesÕ, giving rise to
situations where there is the potential but not the certainty that the exposure of peo-
ple will actually occur. The Commission has issued recommendations for dealing
with potential exposure situations (IAEA, 1990; ICRP, 1993a, 1997b). Protection
in situations involving hot particles is not a new issue (IAEA, 1998b). For these sit-
uations, the Commission has issued criteria of acceptability on the basis of the
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unconditional probability that members of the public would develop fatal stochastic
health effects attributable to the exposure situation (ICRP, 1999), which are expected
to be established by national and international organisations. Such a probability
should be assessed by combining the following probabilities: the probability of being
exposed to the hot particles; the probability of incorporating a hot particle into the
body as a result of such exposure; the incurred average equivalent dose as a result of
such incorporation; and the probability of developing a fatal stochastic effect from
that dose. These probabilities should be integrated over all the range of situations
and possible doses. In establishing such criteria, consideration should be given to
the possibility that localised deterministic effects may also occur as a result of the
incorporation of hot particles. The Commission notes that the risk equivalent to
the public dose limit is about 105/year. An acceptability criterion of approximately
106/year has already been used internationally (IAEA, 1998b).
the event of mass casualties, governments would usually activate the ad-hoc response
plans and national disaster medical systems, which may include disaster mortuary
operational response teams, i.e., response teams, trained in basic radiation protec-
tion, who can provide mortuary assistance.
Burial/cremation
(168) Issues related to both burial and cremation are a function of the amount and
type of radioactive material that remains in the body. Burial is not usually an issue
unless there are extremely long-lived radionuclides present that may ultimately find
their way into the environment in concentrations that exceed regulatory limits.
Whether cremation is allowed depends on what type and amount of radioactive
materials are released to the environment by incineration or by disposal of ashes.
If the radionuclide has a short half-life, it may be possible to wait a few weeks before
cremation occurs. There are a number of national guidelines regarding acceptable
levels of activity in corpses for cremation.
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6. MEDICAL INTERVENTION
(169) The following are essential elements for the medical treatment of people in-
volved in a radiological attack:
All patients should have their traumatic injuries medically stabilised before radi-
ation injuries are considered. Patients should then be evaluated for both external
radiation exposure and radioactive contamination.
People exposed from a source outside the body are said to be Ôexternally exposedÕ.
High external exposure can cause severe tissue damage (e.g., skin burns or bone
marrow depression). This type of ÔexternalÕ exposure does not make the person
radioactive, unless they were exposed to neutron radiation. Even if people have
been exposed to lethal levels of external radiation, they are not a hazard to med-
ical staff.
Nausea, vomiting, diarrhoea, and skin erythaema within 4 h may indicate very
high (but treatable) external radiation exposures. Such patients will show obvious
lymphopenia within 8–24 h, and evaluation for symptomatic patients includes a
complete blood count every 6–12 h for 2–3 days. Primary systems involved will
be skin, intestinal tract, and bone marrow. Treatment should be supported with
fluids, antibiotics, and transfusion stimulating factors. If there are early central
nervous system findings or unexplained hypotension, survival is unlikely (see
Annex B for additional details).
Radioactive material (contamination) may have been deposited on or in the per-
son. More than 90% of surface radioactive contamination is usually removed by
removal of the clothing. Contamination on the skin can be effectively removed
with soap, warm water, and a washcloth. Care should be taken not to damage
the skin by scrubbing. Initial decontamination efforts can usually be stopped
once the contamination level is reduced to two times the background count rate,
or if repeated decontamination efforts are ineffective. These action levels need to
be decided in conjunction with radiation protection experts at the planning
stage. Contaminated clothing should be placed in double-sealed bags/containers
and labelled. Wash water from large numbers of people will usually have to be
disposed of in the sewer system, but this needs to be considered at the planning
stage.
Medical staff can protect themselves against radioactive contamination by observ-
ing standard precautions, including the use of protective clothing, gloves, and a
mask. The principal of time/distance/shielding is key for protection against exter-
nal radiation. Even in the treatment of Chernobyl workers, doses to the medical
staff were not high (about 10 mSv).
From a medical treatment perspective, radioactive contamination in wounds or
burns should be handled as if it were simple dirt. If an unknown metallic object
is encountered, it should only be handled with instruments such as forceps and
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(173) Medical treatment can be more effective if there is readily available data on
the type of radiation that people were exposed to. Data may be basic – such as
whether the radiation was alpha, beta, gamma, neutron, or x rays, or more sophis-
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(174) Experience with accidents in which there was dispersion of radioactive mate-
rials indicates that many people who are not actually injured, exposed, or contami-
nated will still be concerned and are likely to go to hospitals for evaluation. These
people can easily number in the thousands and may arrive at hospitals by private
car and taxi, even before ambulances are able to bring the casualties who need urgent
attention. It has long been realised that hospitals will need to set up and staff a Ôsec-
ondary assessment centreÕ to attend to these Ôworried wellÕ. Such a secondary assess-
ment centre or area will need to have, at the minimum, detection equipment, an
ability to record patientsÕ names, and identifying information, and will need to be
able to perform a cursory medical evaluation. In spite of the fact that this need
has been long recognised, most hospital facilities have not yet made appropriate
planning arrangements.
6.2.3. Biodosimetry
(175) In the very early phases of response, determination of those individuals who
have received high doses (>1000 mSv) and require medical care should proceed as
outlined earlier. While there are a number of useful tools that can be used to record
patient responses and to estimate doses, medical care should not be based on esti-
mated dose but on actual patient response. As a second-order action, there will be
a need to estimate the doses of those individuals who may have received significant
doses but who do not require medical care in the acute or subacute term. Histori-
cally, this has been done using various chromosome and micronucleus assays, but
these methods are time consuming and labour intensive; over the last decade, most
of the competent laboratories have been phased out. Unless these can be revived or
rapid automated techniques developed, dose estimation for these individuals may
only be made with retrospective environmental data (see also section 5.3.2, Biolog-
ical Assays).
more than 7000 immediate casualties and about 20,000 people who will require
intensive care treatment. Local emergency physicians, radiologists, nuclear medicine
physicians, radiation oncologists, medical physicists, and health physicists will all be
involved in the very early hours. Since there are few physicians with the necessary
expertise, others will need to be identified and mobilised if an event arises. It is pos-
sible that additional personnel resources could also be obtained through professional
societies. These issues need to be considered at the planning stage. A very large event
is likely to require international assistance. This could come in response to a national
government requesting assistance through the IAEA or the WHO under the Conven-
tion on Early Notification of a Nuclear Accident. Both of these organisations have
provided assistance following radiological accidents in the past.
(178) A radiological attack might be viewed as having a clear and defined end-
point, recognising that there is likely to be a demand for medical follow-up. This
would initially involve at least providing people with a dose estimate as well as some
information on what risks might be associated with that dose. There may also be spe-
cial needs. For example, if there was a large radioiodine release and KI was not
administered promptly, there would be a need to evaluate infants, children, and ado-
lescents for at least the next decade to assess the possibility of thyroid cancer. The
need for a registry of exposed people or medical monitoring should be considered.
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7. COMMUNICATION
83
ANNEX A: POTENTIAL SCENARIOS
(A2) Some scenarios for a radiological attack are based upon a covert exposure or
dispersal of radioactive material. The first indication that an event has materialised
may be people reporting to hospital with symptoms of radiation illness, burns, or
other symptoms. Therefore, medical planning should include information for physi-
cians and facilities on radiation exposure symptoms, and the establishment of an
effective and centralised monitoring network that is aware of the need for early
reporting of any patient suffering from injuries that may have been caused by expo-
sure to ionising radiation.
A.3. Thefts
(A3) Radioactive material may be stolen, either for a perceived financial benefit or
as a possible precursor to a malicious attack. In any case, these acts should be as-
sessed to determine if they might represent a credible threat and, if so, increase pre-
paredness and/or plan a response to apprehend the perpetrators before a malicious
attack (IAEA, 2002d). Public announcements of the hazard of dangerous sources
may sometimes lead to intelligence resulting in retrieval of the stolen sources. It
should be mentioned that public announcements may also produce anxiety and that
authorities should be prepared. It should be kept in mind that it is equally possible
that quasi ÔlegitimateÕ businesses might be established and radioactive material thus
obtained and used maliciously.
tilation systems; the use of a vehicle to transport a ÔleakingÕ container which streams
radioactive materials behind the vehicle; and the use of a high-rise building to dis-
perse radioactive materials into the air, using normal air currents to disperse the
materials.
(A8) As demonstrated by the accident in Goiânia, Brazil (IAEA, 1988), the disper-
sion of even a relatively limited amount of radioactive material can lead to significant
contamination of an area. The main radiological consequences may include: wide-
spread radioactive contamination of the site; fatalities or casualties suffering from
exposure to radiation, especially if the situation is not immediately recognised or
people intake significant quantities of radioactive materials; and movement of peo-
ple, objects, or vehicles contaminated with radioactive materials away from the site,
causing spread of radioactive contamination.
(A9) Yet another scenario for a radiological attack is the contamination of food or
water supplies with radioactive materials. This centres the attack on the ingestion
pathway, where the aims may be to: expose the public who consume the contami-
nated food or drink the contaminated water; stop the provision of food or water sup-
plies to the public; and cause widespread distress and public alarm. The radiological
consequences may include: contamination of water treatment plants, service reser-
voirs, header tanks, and water supply systems; contamination of food products,
wholesale food markets, supermarkets, or food-processing facilities; and the loss
or disruption of the water and/or food supply chain. Examples of this scenario using
chemicals rather than radiation include the contamination of the pharmaceutical
product Tylenol – in 1982, seven people in the Chicago area died after taking Tylenol
capsules that had been deliberately contaminated with cyanide (Wolnik et al., 1984).
The occurrence of immediate fatalities or casualties suffering from the effects of radi-
ation exposure via the ingestion pathway is very unlikely since extremely large
amounts of radioactive material would be required to achieve sufficiently high con-
centrations and, even if this were to occur, it is very unlikely that it would affect a
large number of people.
radioactive discharges into the environment even following serious accidents. In par-
ticular, nuclear power and research reactors as well as other fuel cycle facilities used
in civilian applications usually have emergency systems in place to prevent radioac-
tive discharges during an accident, which can greatly reduce the potential for radio-
active effluents to be released outside the facility in case of an attack.
(A11) The Commission presumes that any operating nuclear installation has in
place both: (i) strict security measures that would make a successful radiological at-
tack unlikely; and (ii) radiation emergency arrangements that are based on its previ-
ous ad-hoc recommendations (ICRP, 1991b). The technicalities of the radiation
emergency at such facilities may not differ substantially from that expected and
planned for as part of their existing emergency response.
(A12) Finally, an extreme but possible scenario is the diversion of nuclear materi-
als, particularly special fissionable materials6 (such as 235U and 239Pu), and the devel-
opment, construction, and use of a crude nuclear weapon, usually known as an IND.
Even if the IND yield were low, the blast would have devastating consequences.
Moreover, such an event would scatter massive amounts of radioactive fission prod-
ucts into the environment. Significantly, a low-yield IND will disperse the unburned
fissile material.
6
Special fissionable material includes: plutonium, except that with isotopic concentration exceeding
80% in 238Pu; 233U; and uranium enriched in the isotope 235 or 233.
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ANNEX B: MEDICAL ISSUES
(B1) Planning the medical response to the threat of a radiological attack is no dif-
ferent than for other types of attack, e.g. chemical or biological attack. In particular,
the standard procedures for managing persons accidentally contaminated with
radionuclides are applicable (NCRP, 1980). Depending on the planning arrange-
ments made by local authorities, medical facilities may receive a notice that some
type of threat has been made so that they can be prepared if the event actually oc-
curs. As long as the threat has not materialised, special medical provisions may not
be needed.
(B2) Some scenarios for a radiological attack are based upon a covert exposure or
dispersal of radioactive material. The first indication that a covert radiological attack
has occurred may be people reporting to hospital with symptoms of radiation illness,
burns, or other symptoms. Therefore, medical planning should include advance
information to physicians and facilities on radiation health effects so that symptoms
of high radiation exposure can be recognised and proper treatment given. It is essen-
tial that efficient notification arrangements are in place so that a general response can
be initiated rapidly to prevent further exposure. There may also be a need for the
establishment of an effective and centralised monitoring network for the early report-
ing of any patient suffering from injuries that may have been caused by exposure to
ionising radiation.
B.1.3. Irradiation
(B3) The most challenging situation, from a medical perspective, is the possibil-
ity that a very large number of people may have been unknowingly exposed to ion-
ising radiation and that radioactive material may be dispersed throughout the
population. If the identities of the potentially exposed individuals are known,
and if the number is small, existing national medical infrastructures for dealing
with radiological or nuclear emergencies should be sufficient. However, the number
of potentially exposed individuals may overwhelm the existing capabilities and
there may be a need to screen large segments of the population. Furthermore,
the public distress generated by the news could overwhelm the existing infrastruc-
ture. Part of the challenge comes from the fact that many prodromal symptoms of
high radiation overexposure are the same as those of conventional illness, such as
nausea and diarrhoea. For low radiation exposures, no physical symptoms will be
present, potentially leading everyone to believe that they have been exposed. Plan-
ning efforts must, therefore, recognise the need: (i) to establish a national network
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(B5) This type of emergency could occur anywhere, and it is necessary to have a
national network of medical services capable of dealing with the radiological nature
of this type of event. In addition, plans must recognise the security aspects of the
emergency and the need to work in close co-operation with security forces. However,
this is not fundamentally different from the type of planning required to deal with
any conventional accident involving explosive and/or chemical hazards, be they of
an accidental or criminal nature.
(B6) Assuming that medical planning and preparedness measures have been made
for response to nuclear facility emergencies, this type of event should not require any
substantive additional planning. Although the cause may be different (deliberate vs
random accident), the medical consequences would be roughly the same as those that
should be envisaged in the existing plans.
90
Table B.1. Prodromal phase of acute radiation syndrome
Symptoms and ARS degree and the approximate
medical response dose of acute WBE (mSv)
Mild (1000–2000) Moderate (2000–4000) Severe (4000–6000) Very severe (6000–8000) Lethal* (>8000)
Vomiting
Onset 2 h after exposure or later 1–2 h after exposure Earlier than 1 h Earlier than 30 min after Earlier than 10 min after
after exposure exposure exposure
% of incidence 10–50 70–90 100 100 100
Diarrhoea None None Mild Heavy Heavy
Onset – – 3–8 h 1–3 h Less than 1 h
% of incidence – – <10 >10 Almost 100
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Headache Slight Mild Moderate Severe Severe
Onset – – 4–24 h 3–4 h 1–2 h
% of incidence – – 50 80 80–90
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Table B.2. Change of lymphocyte counts in the initial days of acute radiation syndrome (ARS) depending
on the dose of acute whole body exposure
Degree of ARS Dose (mSv) Lymphocyte counts (109/l) after 6 days since first exposure
Preclinical phase 100–1000 1.5–2.5*
Mild 1000–2000 0.7–1.5
Moderate 2000–4000 0.5–0.8
Severe 4000–6000 0.3–0.5
Very severe 6000–8000 0.1–0.3
Lethal >8000 0.0–0.05
* Values in this range can be normal and do not necessarily indicate radiation exposure.
B.2. Relevant information for immediate medical prognosis and initial treatment of
radiation effects attributable to external radiation
(B7) This section presents relevant information for immediate medical prognosis
and treatment of the effects from external radiation that may arise from a radiolog-
ical attack. Although this type of information should correctly be presented in terms
of the absorbed dose and therefore expressed in grays, following the considerations
in Paragraph e of the Executive Summary, doses in the following tables will be ex-
pressed as whole body doses in millisieverts for purposes of simplification. It should
be noted that this simplification does not present serious problems in cases of low-
LET radiation, such as gamma and beta radiation. However, if high-LET external
radiation is involved, such as in an IND, the information in the tables is not appli-
cable. Table B.1 presents the prodromal phase of acute radiation syndrome; Table
B.2 presents the change of lymphocyte counts in the initial days of acute radiation
syndrome depending on the dose of acute whole body exposure; Table B.3 presents
the latent phase of acute radiation syndrome; Table B.4 presents the findings of the
critical phase of acute radiation syndrome following whole body exposure; Table B.5
presents the principal therapeutic measures for acute radiation syndrome according
to degree; and Table B.6 presents the time of onset of clinical signs of skin injury
depending on the dose received (adapted from IAEA, 1998d).
(B8) The procedures recommended for the treatment of people with acute inter-
nally deposited radioactive materials are intended to reduce the radiation dose
and hence the risk of possible future effects which might alter their health. These
aims can be accomplished by the use of two general processes: (i) reduction of
absorption and internal deposition; and (ii) enhanced elimination or excretion of
incorporated radionuclides. Both are more effective when commenced as soon as
possible after exposure. Therefore, the most important considerations in treatment
are selection of the proper drug for the given radionuclide, and timely administration
after exposure. Depending upon the radionuclides used in case of a radiological at-
tack, the main available medical procedures include: (i) blocking, diluting, and dis-
92
Table B.3. Latent phase of acute radiation syndrome
Degree of ARS and approximate dose of acute WBE (mSv)
Mild (1000–2000) Moderate (2000–4000) Severe (4000–6000) Very severe (6000–8000) Lethal (>8000)
ICRP Publication 96
Lymphocytes (109/l) 0.8–1.5 0.5–0.8 0.3–0.5 0.1–0.3 0.0–0.1
(days 3–6)
Granulocytes (109/l) >2.0 1.5–2.0 1.0–1.5 60.5 60.1
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Diarrhoea None None Rare Appears on days 6–9 Appears on days 4–5
Epilation None Moderate, beginning Moderate, beginning on Complete earlier than Complete earlier than
on day 15 or later day 11–21 day 11 day 10
Latency period (days) 21–35 18–28 8–18 7 or less None
Medical response Hospitalisation not Hospitalisation Hospitalisation Hospitalisation urgently Symptomatic treatment
necessary recommended necessary necessary only
ARS, acute radiation syndrome; WBE, whole body exposure.
Table B.4. Findings of critical phase of acute radiation syndrome (ARS) following whole body exposure (WBE)
Degree of ARS and approximate dose of acute WBE (mSv)
Mild (1000–2000) Moderate (2000–4000) Severe (4000–6000) Very severe (6000–8000) Lethal (>8000)
Onset of symptoms >30 days 18–28 days 8–18 days <7 days <3 days
Lymphocytes (109/l) 0.8–1.5 0.5–0.8 0.3–0.5 0.1–0.3 0.0–0.1
Platelets (109/l)
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60–100 30–60 25–35 15–25 <20
10–25% 25–40% 40–80% 60–80% 80–100%*
Clinical manifestations Fatigue, weakness Fever, infections, High fever, infections, High fever, diarrhoea, High fever, diarrhoea,
bleeding, weakness, bleeding, epilation vomiting, dizziness and unconsciousness
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epilation disorientation,
hypotension
Lethality (%) 0 0–50 20–70 50–100 100
Onset 6–8 weeks Onset 4–8 weeks Onset 1–2 weeks 1–2 weeks
Medical response Prophylactic Special prophylactic Special prophylactic Special treatment from Symptomatic only
treatment from days 14– treatment from days the first day; isolation
20; isolation from days 7–10; isolation from the from the beginning
10–20 beginning
* In very severe cases, with a dose >50,000 mSv, death precedes cytopenia.
Table B.5. Principal therapeutic measures for acute radiation syndrome according to degree of severity
ICRP Publication 96
G-CSF or GM-CSF as early as possible (or IL-3 and GM-CSF
within the first week)
95
Antibiotics of broad spectrum activity (from the end of the latent period), antifungal and
antiviral preparations (when necessary)
Blood components transfusion: platelets, erythrocytes (when necessary)
Complete parenteral nutrition (first week) Metabolism correction,
detoxication (when necessary)
HLA-identical Symptomatic
allogene BMT* (first therapy only
week)
BMT, bone marrow transplantation; G-CSF, granulocyte-colony stimulating factor; GM-CSF, granulocyte macrophage-colony stimulating factor; IL-3:
interleukin 3.
* See further discussion of bone marrow transplant in the following section.
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Table B.6. Onset time of clinical signs of skin injury depending on the dose received
Stage/symptoms Dose range (mSv) Time of onset (days)
Erythaema 3000–10,000 14–21
Epilation >3000 14–18
Dry desquamation 8000–12,000 25–30
Moist desquamation 15,000–20,000 20–28
Blister formation 15,000–25,000 15–25
Ulceration (within skin) >20,000 14–21
Necrosis (deeper penetration) >25,000 >21
Stable iodine
(B9) A blocking agent saturates the metabolic process in a specific tissue with a
stable element, thereby reducing the uptake of the radionuclide. Administration of
stable iodine is a practical measure for preventing or reducing the uptake of inhaled
and/or ingested radioactive isotopes of iodine; it is described as a protection of the
public in Chapter 5. After an intake of radioactive iodine, the concentration in the
thyroid reaches 50% of the maximum within about 6 h and the maximum in 1–2 days
in a healthy adult. Thus, to obtain the maximum reduction of the radiation dose to
the thyroid, stable iodine should be administered before any intake of radioactive io-
dine or as soon as practicable thereafter. If stable iodine is administered within the 6
h preceding the intake of radioactive iodine, the protection provided is about 98%; it
is about 90% if stable iodine is administered at the time of uptake. Its efficiency de-
creases with time elapsed since uptake, but radioactive iodine in thyroid can still be
reduced to about 50% if stable iodine is administered within 4–6 h after inhalation. A
single iodine tablet provides efficient protection for about 36 h after its administra-
tion. In most cases of an attack, it will be difficult to anticipate and perform a dis-
tribution of iodine tablets before the malicious contamination of the environment;
this is why the decision to distribute the prophylactic drug and its distribution should
be done as quickly as feasible. Difficulties to meet these obligations are directly re-
lated to the number and geographic distribution of people who need to be treated.
The decision regarding whether and how stable iodine should be made available is
one that has to be taken at the stage of developing emergency plans. Nevertheless,
it should be recognised that, contrary to emergency plans in case of an accident
occurring in a nuclear installation, the identification of the population at risk of a
radiological attack will be very difficult and subject to large uncertainties; these
parameters will make any attempt to distribute stable iodine to large populations
after a malicious attack highly problematic, except if the target of the attack is a
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Dilution, displacement
(B12) Isotopic dilution is achieved by the administration of large quantities of the
stable element that corresponds chemically to the radioactive element, e.g. a high
level of water uptake that will increase the excretion of tritium. Displacement
therapy is a special form of dilution therapy in which a non-radioactive element
of a different atomic number successfully competes with the radionuclide for uptake
sites. An example of a displacement agent is the administration of calcium to
increase the urinary excretion of radioactive strontium. It is unlikely that these
therapeutic means will be of significant use in case of a radiological attack given
the radionuclides that are expected.
Prussian blue
(B13) Gastrointestinal absorption can be reduced either by washing out or by
the use of medications selected for specific radionuclides. These medications com-
bine with the radionuclides so that absorption from the gastrointestinal tract is re-
duced and the radionuclides are eliminated in stools. One simple method is
stomach lavage, which may be useful when, in an exceptional circumstance, an oral
intake of a radionuclide is still in the stomach and would result into high doses.
Ferric ferrocyanide, commonly named Prussian blue, is effective in accelerating
the removal of caesium. Orally administered, Prussian blue traps caesium in the
gut, interrupts its re-absorption from the gastrointestinal tract, and thereby in-
creases faecal excretion. Prussian blue is essentially non-absorbed from the gastro-
intestinal tract and has low toxicity. Classical dosages of 3 g/day of Prussian blue
can reduce the biological half-time of 137Cs by a factor of 2–3. Prussian blue was
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used in the Goiânia accident in Brazil (1987) where several people ingested fatal
and near-fatal levels of 137Cs. This therapy is not usually recommended for those
who have had intakes <1 ALI and is usually recommended for those with intakes
>10 ALI. Prussian blue was not used for the general population in villages around
Chernobyl that were contaminated by caesium. In that case, the lifetime popula-
tion dose was estimated to be over 90% from external radiation due to caesium
on the ground. Once food and water supplies were controlled, the lifetime dose
to the general population from internal contamination was only of the order of
1–2%. Even if the general population had been treated with Prussian blue for
the first 4 years post exposure, this would have reduced final exposure by less than
1%. Another problem with the use of Prussian blue for the general public with very
low intakes of caesium is that, at the present time, there is an insufficient global
supply of Prussian blue.
(B14) Mobilising agents are compounds that increase the natural turnover pro-
cess, thereby effectively eliminating radionuclides from body tissues. These agents
are more effective when given soon after exposure, but some still produce an effect
if given within a few days. Chelating agents may be considered to be a special class
of mobilising agents. Chelation is a process by which organic compounds (ligands)
exchange less firmly bonded ions for other inorganic compounds to form a rela-
tively stable non-ionised ring complex. This soluble complex is excreted readily
by the kidneys. A properly selected and administered chelating drug will therefore
enhance the excretion of some specific radionuclides and thus reduce their resi-
dence times in the organism. Since chelating agents cannot penetrate into cells,
their use is most effective when treatment is commenced immediately after expo-
sure, while the radioactive material ions are still in circulation and before their
incorporation within cells in target organs, such as bone and liver. DTPA is the
most common form of chelating agent used in man, and has shown its effectiveness
in the treatment of contamination by transuranics, such as plutonium, americium,
and curium.
Diethylenetriaminepentaaceticacid (Ca-DTPA)
(B15) The calcium salt of diethylenetriaminepentaacetate (Ca-DTPA) is the
most available form of DTPA. With repeat dosing, Ca-DTPA may deplete the
body of zinc and, to a lesser extent, manganese and other trace elements. Zn-
DTPA is the analogous zinc salt. Ca-DTPA and Zn-DTPA treatments are effica-
cious for treatment of internal contamination with soluble plutonium salts, such
as the nitrates or chlorides (if in a pure chemical form), if treatment is instituted
within several hours of intake. Doses can be reduced by up to 80%. These treat-
ments are, however, ineffective in treating patients contaminated with highly insol-
uble compounds such as the high-fired oxides, or if the radioactive contamination
is associated with other dusts. Prolonged treatment of people internally contami-
nated with poorly soluble plutonium often results in dose reductions of less than
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20%. Ca-DTPA is thought to be more effective than Zn-DTPA for initial chela-
tion of transuranics; therefore, Ca-DTPA should be used, especially in the initial
phase, whenever larger intakes of transuranics are involved, unless contraindi-
cated. Approximately 24 h after exposure, Zn-DTPA is as effective as Ca-DTPA.
This comparable efficacy, coupled with its lesser toxicity, makes Zn-DTPA the
preferred agent for protracted therapy. Ca-DTPA is contra-indicated for children,
pregnant women, and patients with nephrotic syndrome or bone marrow depres-
sion. Zn-DTPA, if clinically indicated, could be administered to children and
pregnant women in all trimesters, although insufficient data exist for both popu-
lations. As with Prussian blue, DTPA therapy is not advised for the general pub-
lic with low or unspecified intakes. It is usually recommended for those with
intakes >10 ALI and not for those with intakes of <1 ALI; between these values,
there is a discretionary element where different actions may be taken depending
on age, health, and likely efficacy of treatment. In most scenarios involving a
radiological attack, the transuranics are likely to be in poorly soluble form. Also,
at the present time, there is an insufficient global supply of Ca-DTPA and Zn-
DTPA to respond to massive malicious events. Furthermore, some countries re-
strict the use of DTPA by limiting it to specified organisations or individuals.
Other countries have yet to authorise DTPA for human use.
Sodium bicarbonate
(B16) Sodium bicarbonate is a useful medical treatment for people exposed to cer-
tain chemical forms of natural, depleted, or enriched uranium. Treatment with so-
dium bicarbonate produces a uranyl bicarbonate complex in tubular urine that is
less nephrotoxic; this complex is stable in biological mediums and is eliminated rap-
idly by the kidneys. The chemical form and particle size of a uranium inhalation
exposure are important factors in determining the clinical effectiveness of sodium
bicarbonate treatment, but unless the uranium is enriched 235U, the hazard is more
chemical than radiological. For example, kidney damage, acute tubular necrosis, is
possible from an exposure of about 4 mg of uranium because in the usual acid urine
pH, the UO2þ2 ion binds to kidney tubules. Treatment of exposure to much lower lev-
els of uranium is not warranted.
(B17) Medical treatment of patients with acute radiation syndrome starts with
triage and immediate life-saving actions, if necessary. During the first day, treat-
ment of whole body overexposure will be directed at symptoms and an attempt
should be made to estimate the order of magnitude of the exposure and its distri-
bution within the body, since these two parameters will allow a prognosis and,
consequently, the nature of the most appropriate treatment. The dose, although
there are marked inhomogenities in dose distribution in most cases, will provide
a general guidance. The initial dose will be estimated through various means, such
as presenting symptoms and laboratory evaluations (lymphocyte, granulocyte, and
platelet counts). After whole body exposure to doses of 2000–15,000 mSv, bone
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marrow is the first organ that may cause death. Therefore, all efforts will be pri-
marily directed to the restoration of its functions and, in some cases, to provide
appropriate substitutes, such as transfusions of blood cells (essentially platelets
and erythrocytes).
(B18) Whatever the type of treatment, the worse risk to the exposed person is the
development of infections, localised or generalised, due to the loss of immune de-
fences. The patient requires anti-infectious aggressive treatments. Prevention mea-
sures in immunocompromised patients are now well established and apply to these
type of patients. The first step of the treatment is prevention of exogenous infection.
Independently of current prophylactic measures, patient isolation is mandatory. The
second step is the elimination of micro-organisms that normally exist in any patient.
Administration of oral, non-absorbable antibacterials will preserve anaerobic bacte-
ria. Antiviral agents will be prescribed in a prophylactic manner. Routine culturing
of skin, body orifices, urine, and wounds, if existing, will allow prompt treatment
with appropriate antibiotics if a fever develops.
(B19) Whole body exposure to doses in the lethal range will induce a severe mal-
nutrition syndrome. Nutritional and caloric balance should be maintained, without
waiting for the appearance of the first signs of imbalance. Caloric administration
should be progressive and reach a plateau between 2000 and 3000 calories, while
respecting equilibrium between proteins, glucides, and lipids. The volume of hydra-
tion depends on the loss related to diarrhoea, vomiting, gastric aspiration, and pos-
sible drainage. Without appropriate hydration, imbalance may cause the death of
exposed people, e.g. after profuse vomiting or diarrhoea.
(B20) When it can be expected that bone marrow will recover, either because the
dose was not high enough to destroy all immature cells (including stem cells and pro-
genitors) or because some territories of the marrow were protected (shielding of
about 10% of the active bone marrow will allow survival of people with a dose
around the LD50/60), classical transfusions may be sufficient to avoid severe compli-
cations related to the transitory depression. When the bone marrow depression is ex-
pected to last for unacceptable periods of time or is too deep for a spontaneous
recovery, other methods have been used, such as bone marrow transplantation, cyto-
kines, cord blood transplantation, or stem cell transplantation.
survival of patients who have had bone marrow transplants after accidental radia-
tion exposure is less than 5%. Bone marrow transplantation has very limited indica-
tions and only in the dose range >8000 mSv. Success will be highly compromised and
some complications might be unavoidable, such as graft-vs-host disease (GVHD)
which represents a great risk of death even without prevailing complicating associ-
ated parameters. Experience has confirmed that bone marrow transplantation has
very little use in accidental overexposures; however, this may change if late multi-
organ failure and other complications can be overcome.
Cytokines
(B22) Haematopoiesis is controlled by factors that act on growth and differentia-
tion, and allow adaptation of the organism to new situations by consequently mod-
ulating its own response. Some of these factors are well identified and can be
produced by biotechnology in sufficient quantities for their use in the treatment of
aplasia. Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macro-
phage colony-stimulating factor (GM-CSF) increase the rate of haematopoietic
recovery and may obviate the need for a bone marrow transplantation, provided that
some stem cells are still viable. Both factors have been used in radiation accidents
during the past decades, and seemed to have some influence on both the length of
the neutropenia period and the survival time; they have also been used in conjunc-
tion with bone marrow transplantation and seemed to have a favourable influence.
They were often combined with another factor, interleukin-3 (IL-3), which affects the
lymphoid system and acts in synergy with GM-CSF. These three factors have non-
negligible side effects, which include fever, headache, pains, and thrombocytopenia.
Other haematopoietic growth factors are used in patients with bone marrow depres-
sion, including erythropoietin, thrombopoietin, IL-6, IL-11, and a fusion protein
consisting of GM-CSF and IL-3 with a greater specific activity than either cytokine
alone (PIX-321). Recently, the suggestion has been made to couple cytokines with
the infusion of cultured immature cells, rich in stem cells and progenitors. This tech-
nique would allow transplantations with a lesser risk of GVHD and a quicker
ÔtakingÕ of the transplant. However, it should be stressed that, at present, there is
an insufficient supply of these cytokines to respond to multiple mass casualty that
might conceivably occur following a radiological attack. Use of these medications
for radiation-induced neutropenia after an attack would be Ôoff-labelÕ. Their use
would require establishing protocols, institutional oversight, adequate monitoring,
and informed consent procedures or adequate exceptions.
(B26) Radioprotective agents have been of interest for both military and cancer
therapy applications. A considerable number of drugs have been tested and Amifos-
tine (EthyolÒ) is considered to be promising. These drugs need to be absorbed prior
to the exposure. They give rise to important side effects such as hypotension, nausea,
and vomiting which severely limits or precludes current use for first responders. Since
there is no clinical evidence that radioprotective agents offer any protection if given
after exposure, they are of no value after a radiological attack has occurred; how-
ever, there is the theoretical possibility that giving the drug might reduce the risks
to life-saving rescuers before they enter an area where they might be exposed to very
high doses.
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ANNEX C: PSYCHOLOGICAL ISSUES
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(C6) Responding to the mental health needs of the community as a whole raises
many challenges. In the immediate aftermath of an event, the affected community
is likely to draw together, but over time, contaminated communities may manifest
anger or reduced cohesiveness, low morale, and decreased social service due to dis-
tress and economic losses. Handouts on stress and fear management techniques and
activities should be prepared for distribution. Contamination of food supplies call
for long-term education and potential health surveillance. Public health outreach
to senior citizens will be important since their distress may heighten their social with-
drawal. Door-to-door contact programmes for this group and those with chronic
medical needs who stay at home will be needed. Establishment of a clinical registry
and appropriate health surveillance may have important psychological benefits for
affected communities. People who have their contact information recorded in a data-
base will feel more assured that follow-up will be available.
(C7) Relocation of families out of zones of exclusion is complicated and requires
particular attention to familial needs and social justice. Maximising the relocation
choices of families is important. Some (perhaps 10%) will not want to move under
any circumstances. Many of those for whom relocation is not recommended will
leave voluntarily. Still others, who might prefer to move, will be unable to do so
due to reasons of employment or an inability to sell their homes in what is likely
to be a depressed housing market. The perception of inequity in these and other mat-
ters will stress social fault lines and may divide communities.
(C8) The imperceptibility of low-level radiation exposures may cause many people
to develop persistent health concerns or to arbitrarily link idiopathic symptoms to
benign or improbable exposures [even under normal circumstances, one-third of pri-
mary care people assist with medically unexplained physical symptoms (e.g. idio-
pathic fatigue and pain)]. Over 90% of the general population will visit their
primary care provider each year, making primary care a crucial setting for dissemi-
nation of accurate health risk information following suspected radiological expo-
sures to the community.
(C9) In the aftermath of a radiation release, primary care providers should make
an effort to determine the degree of exposure suffered by all people visiting their clin-
ics, regardless of the reason. In some circumstances, this determination will be as-
sisted by the use of biodosimetry, but more commonly, it will be based simply on
a personÕs proximity to the event and subsequent location during a critical period
of exposure. Based on this initial primary assessment of exposure, the presence or
absence of symptoms, and the presence or absence of disease (medical and psychiat-
ric), people may be assigned to categories for treatment, follow-up, and education.
Counselling may be provided on risk, symptoms, and/or disease findings. Assessment
for PTSD, depression or anxiety, and altered alcohol or tobacco consumption are
important.
(C10) After a radiation release, it may be useful for primary care clinics to rou-
tinely assess the degree of concern about exposure-related illness, separate from
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ICRP Publication 96
actual exposures. This process can be facilitated by asking, ÔIs your visit today
related to terrorism or radiation concerns?Õ at the beginning of every visit. People
who respond ÔyesÕ or ÔmaybeÕ to this question or who express concern about expo-
sure-related illness should receive extra primary care assessment to elucidate the
nature of their expectations and goals for the medical visit. These concerns and
expectations can then guide medical triage and the intensity of risk communica-
tion efforts.
(C11) Often the primary care provider will have the most difficulty in communi-
cating with those who are: (i) possibly exposed but unconcerned and with no symp-
toms or disease; or (ii) either exposed or unexposed with a high level of concern
but asymptomatic (no symptoms or disease) or unexplained symptoms. The latter
group is often categorised as having multiple idiopathic physical symptoms. People
who were possibly exposed but who are unconcerned with no symptoms or disease
will deny or neglect personal medical needs. Assuming medical needs are subacute,
information should be entered into a local registry to facilitate follow-up to ensure
that people have attended appropriately to injuries and exposures. Exposed or
unexposed people with high levels of concern but who are asymptomatic will am-
plify concerns and repeatedly resist clinician reassurance. In a mass casualty situ-
ation, these people can disrupt provision of critical medical care; therefore, it may
be helpful to plan for this by dedicating staff and an area to their care. Develop-
ment of a contact registry with dedicated efforts to provide follow-up contact and
care is one way of communicating compassion and concern without succumbing to
risky or unnecessary testing. Research suggests that a negative test offers only tran-
sient reassurance and can sometimes increase illness concerns, especially when sub-
sequent false-positive results occur. Discussing the basis for peopleÕs concerns and
exploring which tests a person thinks he/she might need prevents many people
from feeling that such concerns have been ignored. Time-contingent follow-up
(planned rather than as-needed visits) reduces illness worry, increases satisfaction
with care, and may mitigate downstream litigation conflicts and concerns. As with
asymptomatic, concerned people, people who are either exposed or unexposed with
high levels of concern and unexplained symptoms or people with idiopathic symp-
toms can disrupt delivery of critical medical care. These people may invoke more
clinician anxiety because, unlike the people with isolated concerns, they are often
visibly suffering and their symptoms may sound potentially catastrophic (e.g. chest
pain and sweating).
(C12) In addition to a dedicated area, staffing, contact registry, and intensified pri-
mary care follow-up efforts, intervention for people concerned with unexplained
symptoms should involve brochures, fact sheets, and literature about self-manage-
ment approaches to medically unexplained symptoms. In an acute crisis, it is helpful
to triage these people in an area distinct from the area used to care for acutely ill
individuals, but the area should not be labelled or perceived as a Ôpsychiatric careÕ
area for Ôworried wellÕ people because of the sense of stigmatisation that such labels
generate. People with unexplained symptoms should therefore receive early and
frequent validation from the clinician that symptoms are important and will be
followed-up quickly and carefully.
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ICRP Publication 96
C.2. Debriefing
(C13) Physical safety and security of the public and relief workers must take first
priority. After safety is assured, other interventions such as debriefing may begin.
Debriefing is a popular early intervention following disasters, in which small groups
of people involved in the disaster, such as rescue workers, meet in a single lengthy
session to share individual feelings and experiences. Some of these issues might be
considered at the planning stage.
106
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