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GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER–I • EXAMINATION – SUMMER -2018

Subject Code: BP103TP Date: 05/05/2018

Subject Name: PHARMACEUTICS-I
Time: 02:30PM TO 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define posology. Discuss in brief the factors which influence dose. 06
(b) Define prescription. Explain various parts of prescription. 05
(c) Describe Physical instability in emulsion and how to overcome it. 05
Q.2 (a) Describe various types of ointment bases with examples. 06
(b) Give formulas to calculate the dose for child. 05
(c) Explain various test to be performed for identification of types of emulsion 05
Q.3 (a) Differentiate ointment, cream and paste. 06
(b) Discuss Displacement value with suitable example. 05
(c) Classify powders and briefly discuss surgical and medical dusting powders. 05
Q.4 (a) Define Incompatibility. Enumerate various types of incompatibility and explain 06
various types of physical incompatibilities.
(b) Explain in brief sources of errors in prescription. 05
(c) Give Reason 05
1) Citric acid is an important basic material for compounding effervescent
granules.
2) Powder dosage forms are more stable than liquid dosage forms.
Q.5 (a) Explain various mechanisms and factors influencing penetration of drug 06
through skin.
(b) Differentiate Flocculated suspension and Deflocculated suspension. 05
(c) How many parts of 80 %, 65 %, 32 % and 20 % alcohols are to be mixed 05
toghter so as to give 40 % alcohol?
Q. 6 (a) Define Suppository. Describe various types of suppository bases with 06
examples.
(b) Explain various evaluation parameters to be performed for semi solid dosage 05
forms.
(c) Distinguish the following pairs 05
1) Lotions and Liniments
2) Mouth wash and throat paint
Q.7 (a) Describe various techniques used for solubility enhancement. 06
(b) Explain therapeutics incompatibility with suitable examples. 05
(c) Convert 90 % v/v and 40 % v/v alcohol in to proof strength. 05

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GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 1 EXAMINATION – SUMMER -2019

Subject Code: BP103TP Date: 01-06-2019

Subject Name: Pharmaceutics I
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Give the classification of dosage forms with definitions. 06

(b) What are the various parts of prescription? 05
(c) Write a note on ‘Pharmacy as a carrier’. 05
Q.2 (a) What is posology? Discuss the pediatric dose calculations based on age and 06
body weight.
(b) Discuss the imperial systems for weight and measures. 05
(c) Explain with examples: effervescent and efflorescent powders? 05
Q.3 (a) Discuss the Geometric dilutions in powders and explain eutectic mixtures. 06
(b) What are the merits and demerits of liquid dosage forms? 05
(c) Describe the calculation for isotonic solutions based on freezing point. 05
Q.4 (a) Write a note on physical incompatibility with examples. 06
(b) Discuss the method of preparation for lotion and liniments. 05
(c) Give the application site for followings: pessaries, enema, elixirs, gargles, 05
throat paints.
Q.5 (a) Give a note on ‘displacement value’ considered in preparation of suppository. 06
(b) Give the labeling requirements of enema, nasal drops, liniments, ointments and 05
suppository.
(c) How flocculated and deflocculated suspensions have been prepared? 05
Q. 6 (a) Explain in brief: method of preparation of emulsion. 06
(b) Discuss the method of preparation of ointments. 05
(c) Differentiate between suspension and emulsion with examples. 05
Q.7 (a) Explain the mechanisms of dermal penetration of drugs. 06
(b) Discuss the excipients used in semisolid dosage forms. 05
(c) Discuss the chemical incompatibility with suitable examples. 05

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GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph.- SEMESTER–I • EXAMINATION – SUMMER -2022

Subject Code: BP103TP Date: 07/09/2022

Subject Name: PHARMACEUTICS-I
Time: 10:30am to 01:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define terms 1) Mixture 2) Lotion 3) effervescent granules 4) Elixir 5) gels 6) Enemas 06
(b) Write in detail Education and scope of pharmacy. 05
(c) Define Prescription. Discuss parts of prescription with sample prescription. 05
Q.2 (a) Define Posology. How age, body weight and surface area influence calculation of 06
dose. Write equations to calculate child dose based on Age, Surface area and body
Weight.
(b) Write in detail errors associated with prescription writing. 05
(c) What are the different monophasic oral liquids? Discuss excipients used in medicated 05
solutions.
Q.3 (a) Define suppositories. Classify suppository bases. Write ideal properties of Suppository 06
bases.
(b) Write advantages of synthetic suppository base over Cocoa butter. 05
(c) Discuss geometric dilution, displacement values and eutectic mixture. 05
Q.4 (a) Define Emulsion. Classify Emulsion. Discuss instability problems of emulsion and 06
suggest remedy.
(b) Write labelling requirement for lotion, liniment and ointment. 05
(c) Write methods used in Identification of type of Emulsion. 05
Q.5 (a) Define incompatibility. Classify types of incompatibility and discuss therapeutic 06
incompatibility.
(b) Classify suspension. Discuss advantages, disadvantages and method of preparation of 05
suspensions.
(c) Calculate the volume of each 90%, 70 %, 20% alcohol and water required to produce 1 05
liter of 45% alcohol solution.
Q. 6 (a) Differentiate followings 06
1) Cream and ointment
2) Paste and jelly
(b) What do you mean by Tolerated and Adjusted type of incompatibility? 05
Discuss the following prescription and suggest remedy.
Rx
Sodium benzoate
Caffeine citrate
Water.
(c) Discuss in detail chemical incompatibility and suggest remedy with suitable examples. 05
Q.7 (a) Classify the ointment bases. Write Ideal properties of ointment base. Discuss 06
properties of absorption bases in brief.
(b) Write a note on mouthwash and gargles. 05
(c) Discuss formulation, labeling and packaging for effervescent granules. 05
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B.PHARM – SEMESTER – 1- EXAMINATION –WINTER - 2018

Subject Code: BP103TP Date: 05/01/2019

Subject Name: Pharmaceutics I
Time: 10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define the prescription. Discuss in detail parts of prescription. 06

(b) Explain various scope of pharmacy. 05
(c) Define pharmacopoeias. Discuss about IP. 05
Q.2 (a) Define Posology. Explain various factors affecting on Posology. 06
(b) Write down various methods used for calculating the dose for children and 05
infant
(c) Find out the parts of 80% and 30% alcohol to supply 500ml of 50% alcohol. 05
Q.3 (a) Define powder. Classify it and write its merits and demerits. 06
(b) Define following terms (1) Dusting powder (2) effervescent powder (3) 05
hygroscopic powder (4) efflorescent Powder (5) eutectic mixture.
(c) Write a note on solubility enhancement techniques. 05
Q.4 (a) Describe in detail Liniment and Lotions. 06
(b) Define suspension. Give its advantages and disadvantages. 05
(c) Write a difference between flocculated and deflocculated suspension. 05
Q.5 (a) Define emulsion. Write its type. Explain various identification methods. 06
(b) Enlist the methods used to prepared emulsion. Explain any one in detail. 05
(c) Discuss in detail stability problems of emulsion and describe the methods to 05
overcome it.
Q. 6 (a) Define suppositories. Enlist type of suppositories. Writes its advantages and 06
disadvantages.
(b) Write a short note on suppositories base. 05
(c) Define and classify the pharmaceutical incompatibility. Explain physical 05
incompatibility.
Q.7 (a) Write a note on ointment base. 06
(b) Discuss in detail “jellies” one of the best promising semisolid dosage form. 05
(c) Explain the different evaluation parameters of semisolid dosage forms. 05

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GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM-SEMESTER–I EXAMINATION – WINTER -2019

Subject Code: BP103TP Date: 01/01/2020

Subject Name: Pharmaceutics-I
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define prescription. Discuss the parts of prescription with drawing ideal 06
prescription.
(b) Discuss Scope and Potential of Pharmacy as Career. 05
(c) Write in detail about handling of prescription by Registered Pharmacist. 05
Q.2 (a) Classify Solid,liquid and semisolid dosage forms in detail. 06
(b) Define posology.Discuss factors affecting doses. 05
(c) Calculate and suggest: (i) Calculate the quantity of sodium chloride required to 05
prepare 700 ml of a 0.9% solution? (ii) Find the strength of 85% v/v alcohol in
terms of proof spirit.

Q.3 (a) Differentiate the following: (i) Syrup I.P and Syrup U.S.P. 06
(ii) Lotion and liniment.
(b) Comments: (i) Syrup required preservative. 05
(ii) Suspending agent is required in Indiffusible mixture.
(c) Write a note on dusting powders. 05
Q.4 (a) Discuss the labeling requirement for elixir,linctuses and eye drops. 06
(b) Write a note on effervescent powder. 05
(c) Comments: (i) Collapsible tubes are more preffered than glass jar for creams. 05
(ii) Gels and gellies are not required preservatives.
Q.5 (a) Classify ointment base and discuss any one in detail. Classify methods to prepare 06
ointment.
(b) Write a note on flocculated and deflocculated suspension. 05
(c) How many mililitres of a 1:20 v/v solution of a drug can be prepared from 100 05
ml of 6% v/v solution.
Q. 6 (a) Write a note on Chemical type of incompatibility with suitable examples. 06
(b) Discuss suppository bases with examples. 05
(c) Write a note on Nasal drops and Ear drops. 05
Q.7 (a) Define emulsion.Discuss the different types of emulsion? Enlist the 06
identification tests for emulsion.
(b) Write a note on Gargles and mouthwashes. 05
(c) Define suppository. Discuss methods to prepare suppositories. 05

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