India Handbook Notes
India Handbook Notes
HANDBOOK
BIOTECH
HANDBOOK
2024
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INDIA BIOTECH 2024
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TABLE OF CONTENTS
Foreword by ABLE President 04
Program Schedule 30
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Savour the
Best of India’s
Biomanufacturing
Capabilities
G S Krishnan, Hon. President - ABLE
T
he Covid pandemic highlighted the ucts across various industrial sectors. With
need for every country to have its products such as food additives, biophar-
manufacturing capabilities for vac- maceuticals, biogenic dyes, bulk chemicals,
cines, diagnostic kits, anti-virals, protec- animal feed products, flavours/fragrances,
tion kits, syringes and so on. India’s vaccine biomaterials.
manufacturing leadership came in handy
during the pandemic to deliver over 2 billion The opportunities will be huge as India’s
doses of Covid vaccines to the country and $150 billion BioEconomy that accounts for
to many parts of the world. 3.75% of the nation’s $ 4 trillion GDP chugs
along nicely in the years to come. At the core
As we prepare for the next pandemic, India of India’s thriving BioEconomy is the pres-
is embarking on an ambitious program to ence of more than 600 biotech enterprises
enhance national capabilities with an inno- and 8500+ biotech startups. A vast network
vative ‘plug and play’ model of manufac- of 200+ bioincubators and accelerators
turing for biotech products. The backbone spread across the country are aiding the
of this initiative will be the use of advanced growth of the innovative biotech ecosystem.
tools of biotech including synthetic biolo-
gy, genome editing, metabolic engineering In addition, 100+ top quality CDMOs in the
and so on. country are providing a range of services
to companies around the world with best in
As the nation prepares to roll out this initia- class bio manufacturing solutions.
tive this year, we look forward to collabora-
tions from around the world to work with In- Some of India’s top biotech companies will
dian companies and institutions to build the be present in the India Pavilion, set up the
products of tomorrow for the entire world. Association of Biotechnology Led Enterpris-
The pilot scale based biomanufacturing es (ABLE) at the BIO International Conven-
units will employ fermentation using en- tion in San Diego, from June 3-6, 2024. This
hanced microbial cell factories (and suga/ special edition of “India Biotech Handbook
biomass/waste-based raw material) and 2024” provides some glimpses into the in-
so on that are abundantly available in the stitutions and companies that are driving In-
country to manufacture bio-based prod- dia’s $150 billion BioEconomy to the targeted
ucts as an alternative to chemical prod- doubling to $300 billion by the year 2030.
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INDIA’S
BIOECONOMY
A Decade of Dazzling Growth
and Unstoppable Momentum
RANKS #3
in global ethanol
production
13 MN HECTARES
world’s second-largest
cotton producer
25% VACCINES
used worldwide come
from India
670 APPROVALS
FDA-approved facilities
75 INCUBATORS
India’s active bioincubator
network
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Ethanol Cotton King Vaccine Giant: A
Powerhouse: (Almost): India staggering 25%
India ranks #3 reigns supreme as of all vaccines
in global ethanol the world’s second- used worldwide
production, largest cotton come from India!
boasting over 390 producer, with a That’s 1.25 billion
distilleries and whopping 35.5 mn doses keeping
a massive 13.8 bales and 13 mn people healthy!
billion liters of hectares dedicated
capacity! to cultivation!
Global Bioincubator
Manufacturing Boom: India’s
Leader: When bioincubator
it comes to network has
FDA-approved exploded,
facilities outside fostering
the US, India tops innovation with
with around 670 over 75 active
approvals! incubators!
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C
osmos Bio Pvt. Ltd. is an industrial biotech startup, manu-
facturing specialty chemicals for skin protection. Incubated
at the Centre for Cellular and Molecular Platforms (C-CAMP),
Bangalore, it currently produces two biologically active ingredi-
ents, ectoine and hyaluronic acid. Cosmos Bio uses recombinant
DNA technology for both upstream and downstream bioprocessing.
These molecules serve as key ingredients for skin protection and
anti-aging in humans. With a team comprising of protein chemists,
scientists and industry experts, Cosmos Bio aims to become a lead-
er in skin protection chemicals space.
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A 13.7 FOLD
INCREASE
A Breathtaking Trajectory
From a mere $2 billion in 2003, India’s bioeconomy has ballooned to a
staggering $151 billion by 2023, reflecting a remarkable 13.7-fold increase.
This growth trajectory can be segmented into distinct phases:
2.5 times
Growth
400% 173%
Growth Growth
Cumulative Base
of Startups
2662
462
2013 2018 2023 11
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BIOTECH
FUNDING SOARS
Fueling the Innovation Engine
The rise of startups is mirrored by a significant in-
crease in funding. The period 2019-2023 witnessed
a substantial rise in biotech funding deals compared
to 2014-2018. The total funding deals grew from $2.1 2014-18 2019-23
billion to $2.8 billion, with an average annual fund- $2.1 billion $2.8 billion
ing increase from $0.42 billion to $0.56 billion. This
demonstrates growing investor confidence in the
sector’s potential.
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GLOBAL LEADERSHIP
IN KEY BIOSECTORS
India has established itself as a global • Bt Cotton: Bt cotton production in
leader in crucial bioeconomy segments: India has witnessed a 1.6-fold increase,
• Vaccine Production: India has wit- reaching 320 million bales (2014-2024)
nessed a 4-fold increase in vaccine pro- from 200 million bales (2003-2013). This
duction capacity from 2.9 billion doses not only boosts agricultural productivity
(2003-2013) to a staggering 11.5 billion but also positions India as a significant
doses (2013-2023). This remarkable contributor to global textile production.
growth makes India a key player in global India’s bioeconomy has demonstrably
vaccine security. transformed over the past decade.
• Diagnostic Tests: The number of di-
agnostic tests conducted in India has With continued government support, a
grown by 5 times, reaching 5 billion tests thriving startup ecosystem, and a focus
(2013-2023) from 1 billion tests (2003- on innovation, India is poised to maintain
2013). This expansion strengthens In- its impressive growth trajectory and so-
dia’s capacity for early disease detection lidify its position as a global leader in the
and improved healthcare outcomes. bioeconomy.
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INDIA
Gears Up for
Biomanufacturing Boom
Aims for $300 Billion
Bioeconomy by 2030
INDIA HAS SET ITS SIGHTS ON A MONUMENTAL GOAL
A
chieving a $300 billion bio- and Prosperous India.” This nation-
economy by 2030. To propel al endeavor aims to cultivate world-
this growth, a major initia- class expertise, infrastructure, and
tive has been launched to promote a skilled workforce focused on sus-
high-performance biomanufactur- tainable manufacturing practices
ing. This initiative will foster inno- based on synthetic biology.
vation, scale-up production, and
establish robust manufacturing At the heart of this initiative lies
facilities for bio-based commercial a cutting-edge “plug and play”
products. manufacturing model designed
for Industry 4.0. The DBT envisions
This ambitious plan aligns with In- a comprehensive national infra-
dia’s rapidly growing bioeconomy structure platform that leverag-
and the vision of Green Growth es advanced biotechnologies like
outlined in the Union Budget 2023- synthetic biology, genome editing,
2024. Spearheading this initiative is and metabolic engineering to pro-
the Department of Biotechnology pel the synthetic biology capacity
(DBT) with their pioneering program of the biomanufacturing program.
titled “Fostering High Performance Central to this infrastructure are
Biomanufacturing: An Integrated biofoundries – high-throughput fa-
Approach towards Promoting Cir- cilities equipped with cutting-edge
cular Economy for Green, Clean, automation methods like robotics,
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“BEING THERE”
a Contract Research Organisation, supporting a community of small
to medium sized companies be the best versions of themselves.
SERVICES
ABOUT TG
CDSCO, BIS, Ayush, ISO,
ASTM & ASCI Compliant
CONTACT US
+91 088671 25414
[email protected]
www.trialguna.com Flickr - Trial Guna
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Highlights of
BIO2023
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INDIA
Delegation
#BIO2024
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Indrila Sengupta
Asst. Manager-BDO Dr. SK Samal
Association of Biotechnology Director
Led Enterprises (ABLE) Accumark Diagnostics Private Limited
[email protected] [email protected]
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PROGRAM SCHEDULE
BIO International
Convention 2024 INDIA PAVILION
June 3-6 | San Deigo, CA Inauguration in
Booth 4807
on June 3, 2024 | 3 PM
by
Dr. JITENDRA KUMAR
Managing Director
Biotechnology Industry Research
Assistance Council (BIRAC)
MR. RAKESH ADALKHA
Scan the QR Code Deputy Consul General &
to access Commercial Representative
BIO Schedule Consulate General of India
San Francisco, CA, USA
G S KRISHNAN
Hon. President - ABLE
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India's Leading INDIA BIOTECH
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2024
IP Law Firm
Founded in 1994, K&S Partners is India's top tier Intellectual Property (IP) boutique firm, serving
clients in all areas of IP including patents, designs, trademarks, copyrights, geographical
indications, plant varieties and other related laws. With over 150+ professionals spread over
seven locations across India, we serve a large repertoire of Indian and global corporations,
including Fortune 500 companies, research institutes and universities, with a
technology-focused approach. Our affiliate Firm, J. Sagar Associates (JSA), is one of the
largest corporate commercial firms in India.
Advisory Protection
Prior art searches, FTO & Litigation and contentious
infringement analysis proceedings
Landscape study and analysis Oppositions | Revocations |
Invalidity opinions OUR Infringement actions
SERVICES
WHAT WE DO Prosecution
Transactional
Due diligence in M&A Drafting, filing and
transactions; transactional prosecution of patent
support and licensing applications
INDIA
PAVILION
EXHIBITORS
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SERVICES:
Accumark Diagnostics is dedicated to establishing a comprehensive
network of pathology and microbiology investigation units. This network will
encompass:
Fixed Pathology and Microbiology Labs: These brick-and-mortar
Accumark Diagnostics
facilities will provide a central location for patients to access a wide range
Private Limited
of diagnostic tests.
Mobile Investigation Units: Accumark aims to extend their reach through
mobile units,making diagnostic services more accessible in various
locations.
ENTREPRENEURIAL FOCUS:
The company underscores its commitment to developing and training
young entrepreneurs. This initiative empowers individuals to establish and
manage their own investigation units within the Accumark network, fostering
a spirit of self-reliance and increasing healthcare service availability across
Odisha.
CONTACT:
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FOR INQUIRIES OR APPOINTMENTS, YOU CAN REACH ACCUMARK DIAGNOSTICS PRIVATE LIMITED AT 7377292053.
2024
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We develop enzymatic solutions for
chiral intermediates and more...!
Enzyme
Engineering
Improved
High quality targeted variants
Variants
Biocatalysis
Process
Developement
Commercial
Enzyme
Manufacturing
(Fermentors ranging from 5m3 to 60m3)
T
he Bangalore Bioinnovation Centre (BBC) is a government initiative
aimed at nurturing innovation and entrepreneurship within the bio-
technology sector. Located in Bangalore, Karnataka, often referred
to as the “Silicon Valley of India,” BBC strives to cultivate an environment
conducive to biotech innovators, startups, and researchers. Jointly estab-
lished by the Department of IT, BT and S&T, Government of Karnataka, and
the Department of Biotechnology (DBT), Government of India, BBC provides
cutting-edge infrastructure, specialized equipments, mentorship, network-
ing opportunities, and funding support to biotech startups and entrepre-
neurs. Additionally, BBC fosters collaborations among academia, industry,
and government bodies to drive innovation and commercialization in the
biotechnology sector.
BBC plays a crucial role in nurturing the growth of biotech startups, ac-
celerating the development of new biotech products and technologies, and
contributing to the overall growth of the biotechnology ecosystem in India.
The rapid growth and success of the Bangalore Bioinnovation Centre (BBC)
since its establishment in 2016 highlight its effectiveness as a hub for bio-
tech startups in India. Its strategic focus on supporting innovation across
various domains of life sciences, including Healthcare, Medtech, Pharma-
ceutical, Agriculture, food, and nutrition, Industrial biotechnology, Integrat-
ed Veterinary, Bio-IT, Bio-Electronics, Blue economy, sustainability, clean
and climate tech underscores its role in addressing critical challenges and
driving progress in these areas.
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B
ioAgile Therapeutics Pvt. Ltd a distinguished clinical research or-
ganization headquartered in Bangalore, India. Our company special-
izes in delivering comprehensive end-to-end clinical research and
pharmacovigilance services to esteemed pharmaceutical, nutraceutical
and medical device industries.
With a proven track record of over 120 successfully completed studies and
the publication of 30 national and international publications, we take pride
in offering unparalleled expertise to our clients.
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Biological E. Limited, founded in 1953, is the first private sector Our expertise in technology transfer, process development,
biological products company in India and the first pharmaceutical and commercial manufacturing enables us to aid clients across
company in South India various stages of their journey
Supplied more than two billion doses of vaccines for global We offer seamless end-to-end Contract Development and
health. Leading supplier of several life-saving vaccines Manufacturing Organization (CDMO) services for biologics,
and pharmaceutical products to UNICEF, PAHO and many other covering process development to clinical and commercial GMP
global markets manufacturing of drug substances at BSL-2 and Fill-finish
Equipped with state-of-the-art laboratories, R&D facilities, Our aseptic fill/finish manufacturing capabilities include Liquid
and more than 5,000 highly skilled employees, including around and Lyophilized platform technology for vial, ampoule, PFS,
350 scientists cartridge, auto-injectors, and multiple drug-device combinations,
Our facilities comply with rigorous compliance standards as well as Secondary Packaging
established by USFDA, EMEA, WHO, ANVISA Brazil, TGA Australia We are leading in the manufacture of vaccines and
and other regulatory bodies biopharmaceuticals. Our specialty lies in in-licensing and
Our integrated services platform encompasses Microbial, co-development, which aid us in accelerating the production of
next-generation vaccines and RNA therapeutics
CorpCom 4/2024
BIONEEDS
Preclinical Services
PK / TK/
Immunogenicity
Assessment
Analytical &
Bioanalytical
Services
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SERVICES:
Biswa Pharma is dedicated to establishing a supply chain/ network of
pharmaceutica and nutraceutical products supply units. This network will
encompass:
Fixed Services Labs: These brick-and-mortar facilities will provide a
central location for patients to get all pharmaceutical, nutraceutical
products, services.
Mobile Investigation Units: Biswa Pharma aims to extend their reach
through mobile units, making pharmaceutical, nutraceutical products,
services more accessible in various locations.
ENTREPRENEURIAL FOCUS:
The company emboldens its commitment to developing and training young
entrepreneurs. This initiative empowers individuals to establish and manage
their own pharmaceutical, nutraceutical products supplyunits within the
Biswa Pharma network, fostering a spirit of self-reliance and increasing
pharmaceutical, nutraceutical products, service availability across different
locations of India.
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Chemveda harnesses its scientific and technological expertise to
deliver full-suite Chemistry support ranging from lab-scale syn-
thesis to Process R&D, and large-scale custom development of drug
substances, key intermediates, and starting materials across multi-
ple chemistry classes.
C
hemveda Life Sciences is a leading contract research partner to the
pharmaceutical, biotechnology, agrochemical industries, and aca-
demia. As a market challenger, Chemveda is boosting its value cre-
ation along and beyond the drug discovery, development and manufactur-
ing continuum, with an emphasis on:
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D
SK InnoSciences is a growing Contract Research Organization for
Chemistry with a decade of successful operation offering services
to a wide range of global clients such as Pharmaceutical, Veteri-
nary, Agrochemical, Cosmetic, Fragrance, Polymer, Electronic, Specialty
chemicals etc. DSK’s operation is housed in a 30,000 sq. ft. building on five
acres of land in Greater Bangalore, India.
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2024
INDIA BIOTECH
Koncepo
HANDBOOK Scientech
International
Who We Are What We Do
• Established in 2017 | Subsidiary of • Conceptualizing and developing world-
NASDAQ listed company with a 110+ year class technical infrastructure across varied
old presence in Science & Technology sectors such as Life Science, Healthcare,
Sectors Engineering and Technological sectors, for
• Established in 2017 | Subsidiary of the well-being of future generations.
NASDAQ listed company with a 110+ year • Our expertise is to provide an integrated
old presence in Science & Technology platform for the development from
Sectors Strategic Advisory to Design and Build
• 60+ employees | 1000+ employees as a • Sector Expertise: Pharmaceuticals,
group across the world Biophar ma, Heal thcare, P etroleum/
• 50+ Customers include top 6 fortune 500 Petrochemical, Energy Generation &
companies Energy Storage, E-Mobility
Business Verticals
Strategic Advisory
Design Services
Smart Build
Technical Services
Key Achievements
USD 214 Mn Associations 15+ Clients
Business with top 10 With reputed
Investment Lifescience Educational
Advisory companies Conglomerate
5+
2+ million 7+ Advanced
Collaborations
SF Design Futuristic
Lifescience
Assignments Assignments
parks
Clients
Our Focus
Therapeutics Diagnostics
Infectious Diseases
Oncology
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www.mabgenex.com [email protected]
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SERVICES:
Mokshya is dedicated to establishing a comprehensive network of
healthcare support services units. This network will encompass:
Fixed Services Labs: These brick-and-mortar facilities will provide a
central location for patients to access a wide range of diagnostic tests.
Mobile Investigation Units: Mokshya aims to extend their reach through
mobile units, making healthcare equipment, aids, services more
accessible in various locations.
ENTREPRENEURIAL FOCUS:
The company emboldens its commitment to developing and training young
entrepreneurs. This initiative empowers individuals to establish and manage
their own healthcare support units within the Mokshya network, fostering a
spirit of self-reliance and increasing healthcare service availability across
different locations of India.
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We have developed a technology platform for the production
of exosomes with tuneable cargos from clinical-grade human
Mesenchymal Stem Cells, with enhanced anti-inflammatory,
anti-fibrotic, anti/pro-angiogenic, and neurogenic properties
in order to promote regeneration of different tissues.
andorum
BUILDING BLOCKS OF LIFE
P
andorum Technologies is a tissue engineering and regenerative med-
icine company that uses the foundational and translational princi-
ples of biology and engineering to design novel class therapeutic
products. Pandorum has R&D labs and clinical study centres in the US (Pan-
dorum International Inc.) and India (Pandorum Technologies Pvt. Ltd.). We
have developed a technology platform for the production of exosomes with
tuneable cargos from clinical-grade human Mesenchymal Stem Cells, with
enhanced anti-inflammatory, anti-fibrotic, anti/pro-angiogenic, and neuro-
genic properties-in order to promote regeneration of different tissues such
as, cornea (avascular), and brain, liver and lung (vascular).
Pandorum Technologies
www.pandorum.com [email protected]
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De Novo CORNEA
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V
eeda Clinical Research Limited, a leading independent full-ser-
vice Contract Research Organization (CRO), offers comprehensive
drug development solutions from Pre-clinical to Late-stage devel-
opment. Our subsidiaries, Bioneeds and Heads, provide complimentary
services that enhance Veeda’s capabilities. Bioneeds comes up with its
Pre-clinical capabilities, while Heads synergizes its expertise in Late-
stage clinical trials. Together, Veeda gains a broader global footprint, with
trial sites in over 20+ locations, allowing for efficient drug development
services for Pharma and Biopharma companies.
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Veer Medica
ORGANIZATION PROFILE
Veer Medica Private Limited is a medical equipment trading company based in Bhubaneswar,
Odisha, India incorporated on April 17th, 2017 and commencing operations on December 24th,
2023.The company aims to provide comprehensive solutions for hospitals and healthcare
facilities in the region.
OPERATIONS:
Veer Medica currently focuses on trading a wide range of medical equipment, including:
HOSPITAL FURNITURE:
The Company supplies beds, chairs, examination tables, and other furniture essential for patient
care and comfort.
HOSPITAL STATIONERY:
Veer Medica offers essential medical forms, charts, and other consumables used in daily hospital
operations.
MANUFACTURING:
The Company aspires to establish its own manufacturing unit to produce high-quality medical
equipment incorporating the latest technology.
FINANCIAL GROWTH:
The Company aims to achieve a turnover of Rupees 1000 crores within the next five years,
demonstrating significant financial growth.
MARKET LEADERSHIP:
Veer Medica strives to become the leading supplier of
hospital equipment in Odisha, India, catering to the
needs of various healthcare institutions.
With a dedicated team and a clear vision for the future,
Veer Medica Private Limited is poised to make a significant
impact on the healthcare landscape in Odisha, India. Their
commitment to providing high-quality products, coupled
with their ambitious goals for manufacturing and
expansion, positions them well for continued success.
State-of-the-art laboratory with 20,000 SFT animal facility based out of Mysore.
Our Vivarium holds Global certi�cations like OECD GLP, AAALAC and NABL, equipped
with 21CFR Part 11 compliance systems and processes.
Our team has expertise in serving leading pharmaceutical companies in the therapeutic
areas such as Oncology, CNS, In�ammation & Autoimmune diseases, Cardiovascular
diseases, Metabolic & GI disorders, rare diseases and Neuroscience diseases as well.
We deliver scienti�cally rigorous in-depth data which are statistically signi�cant, and
100% regulatory compliant including submissions to FDA, DCGI, EMEA, OECD, and
other relevant regulatory bodies.
OUR SERVICES
Impurity
Discovery Regulatory
Quali cation
Services Toxicology
Studies
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Companies Stall
INDIA PAVILION EXHIBITORS
1 ABLE 4807
2 Biotechnology Industry Research Assistance Council (BIRAC) 4807-D1
3 Biocon Biologics Limited 4807-D2
4 Karnataka Innovation and Technology Society, Government of Karnataka 4807-C1
5 Hi-tech Medical College & Hospitals 4807-C2
India Pavilion
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OTHER INDIAN
EXHIBITORS
Companies Stall
1 Ami Polymer 6051
2 Aurigene Pharmaceutical 5748
Services Limited
3 DDReg Pharma Pvt Ltd 3751
4 Dr. Reddy’s Biologics 6145
5 Jubilant Biosys Limited 4117
6 Kemwell Biopharma Pvt. Ltd. 4953
7 Premas Biotech 4251
8 Rubicon Research Pvt Ltd 3758
9 Syngene International Limited 5757
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MEMBER OF
Join the Community Stewardship initiative of AMRACE (AMR Action Collaborative Engagement)
“Save the existing Antibiotics”
www.microvioma.com
Visit our Website
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OUR STRENGTHS
• Clinical Epidemiological
research centre with ICMR
Registered Clinical Trial Centre.
Supported By
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A
ssociation of Biotechnology Led Enterprises - ABLE is a not-for-
profit pan-India forum that represents the Indian Biotechnology
Sector. It was launched in April 2003, after industry leaders felt a
need to form an exclusive forum to represent the Indian Biotechnology
Sector.
ABLE has over 400 members from all across India representing all verti-
cals of the sector like Agribiotech, Bio-pharma, Industrial biotech, Bioin-
formatics, Investment banks and Venture Capital firms, leading Research
and Academic Institutes and Law Firms and Equipment Suppliers.
The primary focus of ABLE is to accelerate the pace of growth of the Bio-
technology sector in India, through partnering with the Government in
their biotechnology initiatives to deliver optimal policies and create a
positive regulatory environment, encouraging entrepreneurship and in-
vestment in the sector, providing a platform for domestic and overseas
companies to explore collaboration and partnerships, forging stronger
links between academia and industry and showcasing the strengths of
the Indian biotech sector.
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Journal of Clinical Oncology, 2022,Vol
INDIA 40, Issue
2024
35, Page 4095
BIOTECH
A REVIEW
Methods Summary
124 FDA-approved New cancer drugs
substantially reduce
Drugs the risk of death and
tumor progression, yet
255 Solid tumor only marginally extend
indications patient survival
19 Years: Meta-regression of overall survival vs. FDA indication approval sequence. Each indication’s
overall survival HR (y-axis) is mapped against the FDA approval sequence (x-axis). Initial
2003 to 2021 indication approvals are classified as 1, second indication approvals as 2, etc.
Results Introducing
E METASTASIS
TH
SP
2.8 months
ECIA
increase in OS
LISTS
(IQR, 1.97-4.60
months)