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Hoffmann Bromamide Degradation Reaction

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rajwindersingh7507
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41 views1 page

Hoffmann Bromamide Degradation Reaction

Uploaded by

rajwindersingh7507
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

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6 . Jfoffm
ann brom
l Ioffmann amide d e
d grada tion r e a
trcatJng an eveloped a method ction
a fo
of sodJum mide \\1th bromine r preparation o f pr
hy in im
alkyl or ar droxide.. In this de a n aqueous o r et ary
y g ha
to the nitro l group takes place f radation reaction. m nollc
than that gen atom. The am rom carb
o n y l
igra -
carbon o
present in ine so fan f the
0 t h e amide. ned contains
one~
II
I~ - C - r·~
:z + Br2 + 4N
aOH 0

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