LATG Training Manual (2016) Updates and Corrections
Page Original Text Update or Correction
Ch. 5, Page 46, 1st Research facilities using regulated Research facilities using regulated
column species must register with the species must register with the
USDA and update this registration USDA.
every three years.
Ch. 5, Page 58, 2nd the license holder is required to the license holder is required to
column, under report the incident to the Drug report the incident to the Drug
Noncompliance Enforcement Agency for Enforcement Administration for
investigation. investigation.
Ch. 16, p. 193, 1st Drugs that are controlled by the Drugs that are controlled by the
column, under Drug Enforcement Agency (DEA) Drug Enforcement Administration
Controlled are known as controlled (DEA) are known as controlled
Substances substances. substances.
July 2019 Printing Updates
Page Original Text Update or Correction
Page 65, 1st column, often develop non-specific often develop non-specific
3rd line antibodies which interfere with antibodies which interfere with
ELISA or MFI assay. ELISA or multiplex fluorescent
immunoassay (MFI)assays.
Page 150, 1st Delete last bullet
column, last line • Rotaviruses
Page 153, 2nd 2nd paragraph: Move paragraph to Protozoa
column, last Aquatic animals are particularly section in first column as the 2nd
paragraph under prone to protozoan infections. paragraph.
Flagellates Common infections in fish are
velvet disease, caused
by Piscinoodinium, and white
spot, caused by Ichthyophthirius
multifilis. Both organisms are
ectoparasites.
Page 155, 2nd Delete last 2 bullets:
column • Thorny-headed worms
• Leeches
Page 162, 2nd B57BL/6 or B57BL/10 Change to:
column, Ideopathic C57BL/6 or C57BL/10
Ulcerative
Dermatitis, 2nd
sentence
Page 163, 1st Last sentence: Update antisporicidal to sporicidal.
column, Because C. piliforme produces
Tyzzer’s Disease spores, antisporicidal sterilants Because C. piliforme produces
should be used to clear the spores, sporicidal sterilants should
organism from equipment and the be used to clear the organism from
environment. equipment and the environment.
Page 175, 2nd … values are influenced by Change the word “gender” to
column, Complete multiple variables, “sex”:
Blood Count including age, gender, stress, and
individual variation …values are influenced by multiple
variables, including age, sex, stress,
and individual variation
Page 219, Other variables may be the Change the word “gender” to
1st column, 1st line gender, age, strain, and “sex”:
health status of the animals.
Other variables may be the sex,
age, strain, and
health status of the animals.
Page 219, Other factors to be addressed are Change the word “gender” to
2nd column, 2nd gender (males usually “sex”:
paragraph grow faster and larger than
females), age…. Other factors to be addressed are
sex (males usually grow faster and
larger than females), age….
Page 219, Change the word “gender” to
2nd column, 2nd …then she must start with rats of “sex”:
paragraph the same weight, age, gender, and
stock or strain. …then she must start with rats of
the same weight, age, sex, and
stock or strain.
December 2017 printing
Page Original Text Update or Correction
P. vii, Table of Change page 35 to page 37.
Contents
Chapter 4: Facility Security & Chapter 4: Facility Security &
Disaster Planning 35 Disaster Planning 37
P. 34 – 1st column, NIH's Cost Accounting and Rate NIH's Cost Analysis and Rate
third paragraph Setting Manual Setting Manual
from the top
P. 38, 2nd column, Delete "entered" from first
3rd bullet sentence.
Do windows offer a clear view of Do windows offer a clear view of
the interior, and are those the interior, and are those
windows easily accessible windows easily accessible?
entered?
P. 41 2nd column, Delete "smoke detectors".
bottom – under Advance planning to handle the Advance planning to handle the
“2. Prepare” effects of disasters includes effects of disasters includes
activities such as installing activities such as installing
emergency equipment, fire emergency equipment, fire
extinguishers, smoke detectors, extinguishers, and developing
and developing evacuation plans. evacuation plans.
Page 48. 2 column,
nd Change chapters of the Guide to:
#2 • Institutional Policies and • Key Concepts
Responsibilities; • Animal Care and Use
• Animal Environment, Program
• Housing, and Management; • Environment, Housing, and
• Veterinary Medical Care; Management
and • Veterinary Care
• Physical Plant. • Physical Plant
P. 78, Figure 7.1., 1st Change "Corrosion" title to "Health
box of image Hazard" in first image; Change
"Environmental" to "Environment"
in bottom row, 2nd image.
P. 80, 1st column, Add the word “and” to sentence.
last paragraph, 2nd Risk factors for developing animal Risk factors for developing animal
line allergies include genetic allergies include genetic
predisposition, the degree and predisposition, and the degree
duration of environmental and duration of environmental
exposure. exposure.
P. 96, Figure 8.1 Add A, B, and C labels.
P. 108, 1st paragraph Change " i10.1t" to "it".
Under Transcription, Transcription is an essential step in Transcription is an essential step in
2nd line up from that process; i10.1t is the synthesis that process; it is the synthesis of a
bottom of of a messenger between the two messenger between the two sites.
paragraph sites.
P. 135, Figure 12.1. Add" a" and "b" labels on image as
in figure caption.
P. 139, Figure 12.4, Delete "Cell mediated Immunity".
caption Figure 12.4. The basic structure of Figure 12.4. The basic structure of
an antibody molecule, which is an antibody molecule, which is
shaped like a Y. Each molecule shaped like a Y. Each molecule
contains 2 heavy chains and 2 light contains 2 heavy chains and 2 light
chains. Cell mediated Immunity chains.
P. 156 Figure 13.8, Delete "(e) Armilifer armillatus, a
caption pentastome of the rat."
Figure 13.8. Examples of the Figure 13.8. Examples of the
common types of arthropods and common types of arthropods and
the laboratory species they may the laboratory species they may
infest. (a) Haemaphysalis leporis- infest. (a) Haemaphysalis leporis-
palustris, a tick of rabbits. (b) palustris, a tick of rabbits. (b)
Pedicinus sp., a louse of nonhuman Pedicinus sp., a louse of nonhuman
primates. (c) Psoroptes cuniculi, a primates. (c) Psoroptes cuniculi, a
mite of rabbits. (d) Cediopsylla mite of rabbits. (d) Cediopsylla
simplex, a flea of rabbits. (e) simplex, a flea of rabbits.
Armillifer armillatus, a pentastome
of the rat.
p. 163, right column, There is no effective treatment, Treatment of coccidiosis is difficult,
under Coccidiosis although sulfa drugs may help although sulfa drugs may be
signs of the disease. effective in controlling disease.
P 177, Figure 15.2. Image was replaced.
Image is cropped, so
that only 1½ of 3
images are seen.
p. 195, right column, Add parasiticides after “widely
under Ivermectin, used” and correct spelling of
first line "animal."
Ivermectin is one of the most Ivermectin is one of the most
widely used in laboratory animlal widely used parasiticides in
medicine and is most often laboratory animal medicine and is
prepared by diluting an injectable most often prepared by diluting an
formulation. injectable formulation.
Page 200, 2nd Because these animals are Change "Because" to "If".
column, 4th line coprophagic, measures should be If these animals are coprophagic,
from the bottom taken to prevent them from measures should be taken to
ingesting their feces during the prevent them from ingesting their
fasting period. feces during the fasting period.
Page 203, 1st Change "sedative and analgesic" to
column, Alpha-2- "sedatives and analgesics".
Adrenergic Agonists, Nevertheless, it is an excellent Nevertheless, they are excellent
6th line sedative and analgesic for many sedatives and analgesics for many
species. species.
Page 205, 2nd In table header, change “Color” to
column, Table 17.1 “Tank Color”.
Page 205, 2nd Change "tank attached the" to
column, Inhalant "tank attached to the”.
Anesthetics, 6th line These agents are in liquid form and These agents are in liquid form and
are vaporized in an anesthesia are vaporized in an anesthesia
machine and delivered in oxygen, machine and delivered in oxygen,
the carrier gas, delivered either the carrier gas, delivered either
from a pipeline or a tank attached from a pipeline or a tank attached
the anesthesia machine. to the anesthesia machine.
Page 221, Left Change "Figure 17.2a" to "Figure
column, last line 18.2a".
The means for both sets of The means for both sets of
measurements are identical (10), measurements are identical (10),
but the individual measurements but the individual measurements
are more spread out (from 6.5 to are more spread out (from 6.5 to
13.5) in Figure 18.2b compared to 13.5) in Figure 18.2b compared to
Figure 17.2a (from 8.0 to 12.0). Figure 18.2a (from 8.0 to 12.0).
Page 221, Right Information for the two curves was
column, 1st switched. Change text to:
paragraph, last 2 For the curve shown in In Figure For the curve shown in Figure
sentences 18.2a, the individual data values 18.2a, the individual data values
are more widely dispersed around are tightly clustered near their
their mean with a standard mean with a standard deviation of
deviation of 1.6. In Figure 18.2b, 0.99. In Figure 18.2b, the individual
the individual data values are data values are more widely
tightly clustered near their mean dispersed around their mean with
with a standard deviation of 0.99. a standard deviation of 1.62.
