Orofacial Pain
Dr. Maimoona Siddiq
• pain associated with the hard and soft tissues of the head, face,
oral cavity and neck.
• Pain Transduction is the conversion of a nociceptive stimulus to a
transmissible neuroelectrical signal
• It refers to activation of specialized nerves: A-Delta, C fibres
• Pain Transmission is the relay functions by which the message is
carried from the site of tissue injury to the brain regions underlying
perception.
• Pain Modulation neural process that acts specifically to reduce
activity in the transmission system
Pain Fibers
Classification of Orofacial Pain
• Somatic:
I. Visceral: TMJ pain, Salivary Gland
II. Odontogenic
III. Musculoskeletal : Myofacial Pain Dysfunction syndrome( MPDS )
• Neuropathic:
I. Nerve injury (trauma)
II. Trigeminal Neuralgia
III. Neuroma
IV. Post Herpetic
• Psychological: very rare
• Pain of Unknown Origin: Atypical Facial Pain (may or may not be
associated with psychogenic cause)
Glossary of Pain
Neuropathic Facial Pain
• Trigeminal Neuralgia
Trigeminal Neuralgia
• Age above 50 years
• incidence 8 : 100,000
• female-to-male ratio 1.6 : 1
• sharp, electric shock like pain in nerve distribution area
• Intense pain, lasts for few seconds to 1 minute, followed by a
refractory period
• a trigger zone is present: mechanical stimuli such as soft touch may
provoke an attack
• Common cutaneous trigger zones: corner of the lips, cheek, ala of the
nose, lateral brow, any intraoral site.
HOW TO MAKE DIAGNOSIS?
• History and pain character
• Examination
• Diagnostic nerve block
• MRI and radiological investigation
• Consult Neurologist if suspected Central lesion/disease
Pathophysiology
• Pressure on root entry zone (near Pons of brain stem)of tri-germinal
nerve by vascular loop, leading to demyelination
• Superior Cerebellar Artery
• Other diseases which have
similar symptoms: Brain Tumors,
Lyme Disease,
Multiple Sclerosis
Trigeminal Neuralgia
MANAGEMENT
MEDICAL:
Trigeminal Neuralgia
SURGICAL MANAGEMENT
PERIPHERAL CENTRAL
• Nerve resection • Microvascular Decopression
• Cryotherapy • Gamma Knife radiosurgery
• Absolute Alcohol Injection • Percutaneous Needle Rhizotomy
• Glycerol Injection • Balloon Compression of root
entry zone
Post Herpetic Neuralgia
• 80% V1 dermatome involved
• 10-15 % occurs in cases of Shingles ( herpes zoster)
• Neuralgia associated with rash in specific cutaneous dermatome
Neuroma
• After peripheral nerve transection, proximal portion of the nerve forms
sprouts in an effort to regain communication with the severed distal
component.
• sprouting occurs without distal segment communication, a stump of
neuronal tissue, Schwann cells, and other neural elements form.
• This stump, can become exquisitely sensitive to mechanical and chemical
stimuli
• burning or shocklike pain
• Frequently a positive Tinel sign is present.
TINNEL SIGN: tapping over the suspected neuroma produces sharp,
shooting, electric shock like pain