Hydrogenated Soya Lecithin
NIKKOL LECINOL® S-10
Special Materials / Active Materials
Oil Materials
Emulsifiers / Solubilizers / Dispersants
Thickeners / Gelling Agents / Film Former
Foaming Agents / Detergents
Conditioners
Blends / etc.
Hydrogenated Soya Lecithin
®
NIKKOL LECINOL S-10
R1COOCH2
|
R2COOCH O R1,R2 : Hydrogenated Alkyl
| ||
H2CO－P－OX X : Phosphatidyl Choline
|
O-
INCI name : HYDROGENATED LECITHIN
JCIC name : Hydrogenated Soybean Phospholipid
CLS ingredient code : 42-506017
CAS number : 92128-87-5
EINECS number : 295-786-7
Lecithin is one of the most important components of a cell and plays an
important role in its metabolism, especially in its constitution and membrane
penetrability. For many years its use as a bio-surfactant in cosmetics has been
studied. However, its application to cosmetics has been limited because of its
oxidation and instability against heat.
NIKKOL LECINOL® S-10 retains all the good qualities of natural lecithin,
yet its stability is greatly improved. Moreover, unlike common surfactants,
NIKKOL LECINOL® S-10 forms stable liposomes when it is dispersed in water,
which can be involved both water-soluble and lipo-soluble substances.
Ⅰ. Physical properties
Appearance : Slight yellow to light yellow powder with faint characteristic odor
Acid Value : 40 max.
Iodine Value : 10 max.
Loss on Drying : 2.0% max. (3g, 105℃, 1 hour)
1
Ⅱ. Stability against Oxidation
Fig. 1 shows the stability against oxidation of NIKKOL LECINOL® S-10 versus
Soya Lecithin at 60℃.
40
30
POV
20
Soya Lecithin
Egg Yolk Lecithin
10
0
0 10 20 30 40 50 60
Preservation Period (day)
Fig. 1 Stability against oxidation
Ⅲ. Stability against Heat
Fig. 2 shows the stability against heat of NIKKOL LECINOL® S-10 versus
Soya Lecithin, showing the permeation and variation rate of various wavelengths
after 95 days at 60℃. The results show that NIKKOL LECINOL® S-10 is more
stable than Soya Lecithin against heat.
(%)
120
Initial
80 120 80 (%)
Initial
After 95 days 70 After 95 days
100 Rate of Decrease Rate of Decrease 70
100
Wavelengths Permeation
60
Wavelength Permeation
60
Variation Rate
Variation Rate
80 80
50 50
60 40 60 40
30 30
40 40
20 20
20 20
10 10
0 0 0 0
380 400 450 500 380 400 450 500
Wavelengths (nm) Wavelength (nm)
Soya Lecithin NIKKOL LECINOL® S-10
Fig. 2 Stability against heat
2
Ⅳ. Compatibility with Other Surfactants
Compatibility with other surfactants is important when we formulate detergents
include NIKKOL LECINOL® S-10. The following tables show the compatibility of
various concentrations of NIKKOL LECINOL® S-10 as 20% aqueous solution with
anionic, cationic and amphoteric surfactants at 2, 25, 60℃.
Table 1 Compatibility with anionic surfactants
LECINOL® SAA NES-203-27 1) SLS 2) Sarcosinate LN 3) DLP-10 4)
S-10 (%) ℃ 2 25 60 2 25 60 2 25 60 2 25 60
0
10
20
30
40
50
60
70
80
90
1): Sodium C12-15 Pareth-3 Sulfate 2): Sodium Lauryl Sulfate
3): Sodium Lauroyl Sarcosinate 4): Dilaureth-10 Phosphate
Table 2 Compatibility with cationic and amphoteric surfactants
LECINOL®S-10 SAA CA-101 1) CA-2450 2) AM-301 3)
(%) ℃ 2 25 60 2 25 60 2 25 60
0
10
20
30
40
50
60
70
80
90
1): Benzalkonium Chloride 2): Steartrimonium Chloride 3):Lauryl Betaine
Transparent liquid Solid
Opaque slightly viscous liquid Phase separation
Opaque viscous liquid
3
Ⅴ. Solubility
Table 3 shows the solubility of NIKKOL LECINOL® S-10 into common
cosmetic raw materials at 25 and 80℃.
Table 3 Solubility in cosmetic raw materials
Cosmetic raw Temperature 25℃ 80℃
materials Concentration 1% 5% 1% 5%
Ethanol I I I I
Propyleneglycol I I I TD
5% Propyleneglycol aq. soln. I D TD I
Glycerin PS D S S
5% Glycerin aq. soln. D D TD TD
2-Hexyldecanol I I S S
Cetyl Octanoate I I S S
Trioctanoin I I S S
Corn Oil I I I I
Squalane I I S TD
S: Soluble I: Insoluble D: Dispersion
PS: Partially Soluble TD: Semi-Transparent Dispersion
Ⅵ. Efficacy on Foaming Power of Detergent
This figure shows the efficacy of NIKKOL LECINOL® S-10 on the forming
power of anionic surfactant using the Loss & Miles Method. According to the
results, NIKKOL LECINOL® S-10 makes foam luxurious without decreasing its
volume.
250
Initial After 5 min
200
Height (mm)
150
100
50
0
1 2 3
1: Sodium C12-15 Pareth-3 Sulfate (0.25wt%)
2: Sodium C12-15 Pareth-3 Sulfate / Soya lecithin (0.25wt% / 0.25wt% )
3: Sodium C12-15 Pareth-3 Sulfate / LECINOL® S-10 (0.25wt% / 0.25wt%)
Fig. 3 Efficacy on foaming power of detergent
4
Ⅶ. Safety
Modification effect of skin irritation was investigated pathologically using
0.5% NIKKOL LECINOL® S-10 with Sodium Lauryl Sulfate (SLS, 5% aq.).
Results are shown in Table 4. The presence of NIKKOL LECINOL® S-10
resulted in a significant reduction of SLS-induced irritation. The results
suggested that NIKKOL LECINOL® S-10 has the efficacy to reduce the skin
irritation caused by other ingredients.
[Method]
Hartley albino guinea pigs (six in a group) were used in this test. Before
the test, hair was shaved from the dorsal of the trunk. Each animal received
test material, each of which was applied under gauze with occlusive patch for
48 hours. Two hours after the removal of the patch the application sites were
scored. Then necropsy with gross-pathological examination was carried out.
Table 4 Comparison of skin irritation score
Distilled Propylen SLS(0.5%) NIKKOL SLS(0.5%)
Water Glycol (5%) LECINOL® +NIKKOL
S-10 LECINOL®
(0.5%) S-10 (0.5%)
Hyperkeratinization 4 7 9 8 1
Gulanular layer gain 5 6 11 4 5
Thick in percutaneous 6 7 12 5 10
Chromosome singular 0 0 2 0 0
Achromocyte 7 6 6 3 7
Incomplete keratinization 0 0 8 0 0
Eschar formation 0 0 0 0 0
Gulanular layer reduction 0 0 0 0 0
Oedema 3 1 0 5 7
Infiltrate of epidermal cell 2 1 7 0 0
Infiltrate of dermal 6 8 17 6 11
inflammatory cell
Congestion 9 11 18 8 14
Collagen fiber breakage 7 8 16 6 12
Collagen fiber swelling 7 8 12 9 10
Score 56 63 118 54 77
5
Ⅷ. Formulations
(1) Milk Lotion
(A) NIKKOL LECINOL® S-10 (Hydrogenated Lecithin) 5.0 wt%
NIKKOL GM-18IS (Batyl Isostearate) 1.0
NIKKOL Trifat S-308 (Trioctanoin) 4.0
Butylparaben 0.1
(B) 1, 3-Butyleneglycol 5.0
Methylparaben 0.1
Distilled Water 84.8
(C) Perfume qs
Procedure: Heat (A) and (B) in separate vessels at 80℃. Add (B) to (A) and
mixing until uniform. When (A)+(B) is at 50℃, add (C). Cool to desired filling
temperature.
(2) Lotion
(A) NIKKOL LECINOL® S-10 (Hydrogenated Lecithin) 2.0 wt%
Ethanol 10.0
Sorbitol (70%) 3.0
Glycerin 3.0
Dipotassium Glycyrrhizinate 0.1
Methylparaben 0.1
Distilled Water 81.8
(B) Perfume qs
Procedure: Heat (A) with continued slow sweep agitation. Cool to 50 ℃ and
add (B).
(3) Hair Conditioner, Treatment
(A) NIKKOL LECINOL® S-10 (Hydrogenated Lecithin) 2.0 wt%
NIKKOL BO-2 (Oleth-2) 5.0
Swanol CA-2465 (Steartrimonium Chloride) 7.7
NIKKOL IPM-EX (Isopropyl Myristate) 9.0
2-Octyldodecanol 4.0
Behenyl Alcohol 2.0
(B) Distilled Water 70.3
(C) Perfume qs
Procedure: Heat (A) and (B) in separate vessels at 80℃. Add (B) to (A) and
mixing until uniform. When (A)+(B) is at 50℃, add (C). Cool to desired filling
temperature.
6
*We do not guarantee the stability of final product formulations in this brochure though
the stability was checked at 40℃ for 3 weeks.
「Public | December 1984 | NIKKOL LECINOL® S-10」
©1984 NIKKOL GROUP All Rights Reserved.
1st revised: Feb. 1999
