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How To Calculate The Maximum Dose

The document outlines the steps to calculate the maximum dose of local anesthesia based on body weight, specifically for lidocaine, including the calculations for total milligrams in a carpule and the maximum number of carpules. It also details how to calculate the amount of adrenaline in each carpule and the maximum allowable dose for cardiac patients. Additionally, it provides information on dosing local anesthetic agents without a vasoconstrictor, emphasizing the recommended limits and absorption considerations.

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Muharrm
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122 views2 pages

How To Calculate The Maximum Dose

The document outlines the steps to calculate the maximum dose of local anesthesia based on body weight, specifically for lidocaine, including the calculations for total milligrams in a carpule and the maximum number of carpules. It also details how to calculate the amount of adrenaline in each carpule and the maximum allowable dose for cardiac patients. Additionally, it provides information on dosing local anesthetic agents without a vasoconstrictor, emphasizing the recommended limits and absorption considerations.

Uploaded by

Muharrm
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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How to calculate the Maximum Dose of each type of local anaesthesia

according to body weight with vasoconstrictor?

 First step you have to know the Maximum recommended dose of


each local anaesthesia type mentioned in the following table
• Maximum recommended dose is a dose given by the
manufacturers after exceeding these doses potential local
anaestheisa toxicity may occur.

 Second step : you have to determine the pt. weight here we will say
that the mean Yemeni pt weight is 70kg
 So to calculate the Maximum dose we will use the following
equation
Pt. weight X MRD of the local anaesthesia for example lidocaine
which is the most commonly used local anesthetic
70 kg X 7 mg = 499 mg

 Third step : how to calculate the total amount in milligrams of LA


in the carpule use the following equation given that the size of LA
carpule in yemen is 1.8ml

Total milligrams= % of the solution X 10 X total millilitres


2% lidocaine X 10 X 1.8 which means
20 X 1.8 =36 mg lidocaine in each carpule

 Fourth step: how to calculate the maximum number of carpule of


lidocaine

Pt weight 499 = 13.8 carpule


Amount of lidocaine in each carpule 36
How to calculate the amount of adrenaline in each carpule?

Use the following equation:


 1:80,000 = 1000 = 0.0125mg/ml
80,000
 1:100,000 = 1000 = 0.01mg/ml
100,000
 1:200,000 = 1000 = 0.005mg/ml
200,000
So the dose 1:80,000 adrenaline in 1.8ml carpule =
0.0125mg/ml X 1.8ml = 0.0225mg

How to calculate the maximum allowable vasoconstrictor of the cardiac


patient

The dose in pt. with cardiac disease should not exceed 0.04 mg
So if you have lidocaine 1:80,000 this means it contains 0.0225mg adrenaline
then you should not give him more than 2 carpules

STANDARD
VASOCONSTRICTOR MAXIMUM
VASOCONSTRICTOR DENTAL
CONCENTRATION ALLOWED
(MG/ML) CARTRIDGE
AND TYPE CARTRIDGES
(MG/1.8 ML)
1:50,000 Epinephrine 0.02 0.036 1
1:80,000 Epinephrine 0.0125 0.0225 2
1:100,000 Epinephrine 0.01 0.018 2
1:200,000 Epinephrine 0.005 0.009 4

How to calculate the dose of Local anesthetic agents without a


vasoconstrictor:
 The recommended dose of lidocaine, without a vasoconstrictor is 4.4
mg/kg BW, but not to exceed 300 mg.
 A lesser dose is recommended because of faster absorption of the local
anesthetic agent.
 This dose will be contained in 15 ml or 7½ carpule of the local anesthetic
solution.

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