Amity/Tech Data/Virusolve+ conc

Virusolve®+ concentrate
Specialized Cleaning and High Level Disinfecting
Fluid
Technical Information
Description & Application:
Virusolve+ is a complex blend containing the latest dodecylamine based structures, solvents and fully non-toxic,
biodegradable detergent. The formulation does not contain any hazardous aldehydes or chlorine generating
components.
The formulation is highly effective as a cleaner and terminal high level disinfectant (HLD) against bacteria,
bacterial spores, fungi and viruses. The product is designed to eliminate the risk of cross-infection from viruses,
fungi and bacteria. Virusolve+ does not simply render the microorganisms inert but has been demonstrated to kill
these by disrupting the RNA of the microorganisms.
It is safe to use on any surface and is odourless and colourless.
Virusolve+ is available for supply as a concentrate – fragrant and non-fragrant (this data sheet), as a Ready-to-
Use (RTU) solution and as an impregnated wipe. The RTU and Wipe products are described fully in separate
Technical Data Sheets (TDS).

Primary features attributable to Virusolve+ concentrate are:

• Suitable for high level disinfection and cleaning, contains powerful germicides;
• Low toxicity, does not contain chlorine or aldehyde compounds;
• Highly effective over a wide range of viruses, bacteria, fungi, yeasts and moulds, including MRSA,
Hepatitis B and HIV agents;
• Highly effective against bacterial spores;
• Effective against the difficult non-enveloped type viruses such as Polio, Adenovirus and Norovirus;
• Non-selective;
• Versatile, simple to use and cost effective;
• Approved by accredited laboratories.

Applications
Virusolve+ concentrate is ideal for removing biohazards in hospitals, health centres, dentists, vets, nursing
homes, laboratories, food preparation areas and any environment where the risk of cross-infection needs to
be eliminated, e.g. cruise ships.
Virusolve+ is suited for cleaning and disinfection of hard surfaces, walls, floors, glasswork and
contaminated laundry.
It can also be used to disinfect medical and surgical instrumentation.
It can also be used to disinfect hairdressing equipment.

Infection
Certificate No. Controlled
Certificate No. GB06/69741 Certificate No. GB06/69740 GB19/964425

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Compatibility
Virusolve+ concentrate is compatible with a wide range of fabrics, rubbers, plastics and hard surface
materials when diluted to normal working strength.
In the concentrate form there may be slight staining or attack on some materials such as aluminium, zinc
and some plastics so care needs to be exercised prior to dilution.

Order Information
Virusolve+ concentrate can be made available as a fragrant grade when requested.
4 versions are currently available to order:
- Lavender version order code - L
- Lemon version order code - LE
- Orchid version order code - O
- Pine version order code - P
Users should specify the required fragrance at time of order otherwise the non-fragrant version will be
supplied.

Health and Safety

Virusolve+ is not flammable and is neither a known or suspected carcinogen, is non-hypoallergenic, and is
fully biodegradable.
Virusolve+ is classed as Corrosive to skin and eyes in the concentrate form but is non-hazardous when
diluted to normal working strength and used according to the specified user directions.
Virusolve+ is intended for external use only.
In the ‘concentrate’ form contact with skin and eyes should be avoided. Suitable protective clothing, gloves
and eye/face protection should be used
However when diluted to normal working strength Virusolve+ can be safely used in contact with skin and in
the ‘Ready-to-Use’ form the product is classed as being non-harmful.

See Safety Data Sheets for details.

Typical Properties

Appearance Pale straw coloured liquid

Odour Slight amine (fishy) odour
pH, (typical) 12.4 units (neat)
11.6 (10% solution)
11.2 (5% solution)
11.0 (1% solution)
Density, g/cm3 @ 20 C 1.02 (neat)
Solubility in water Complete
Flash Point (Abel closed cup) None

Shelf Life of Concentrate

4 years in unopened original containers when stored between 5 C and 35 C out of direct sunlight.

Virusolve+ in contrast to other disinfectants is capable of penetrating the outer membranes of the bacteria
and viruses and as a result renders the genome material within the cell inactive. This is in contrast to other
disinfectants in the marketplace that are composed of chemicals that may well inactivate the cells for a
period of time, preventing growth, but after a period the cells will regenerate and multiply.
Virusolve+ will inactivate the cell to the point where the RNA is destroyed and therefore preventing
replication.

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Virusolve+ will also attack all single strand transcriptase positive and transcriptase negative viruses within
similar families.
Virusolve+ has been thoroughly tested by independent laboratories and demonstrated to be effective
against gram negative and gram positive bacteria, viruses and fungi/yeasts.

Efficacy data has been raised against the following specific organisms:
Bacteria:
Acinetobacter calcoaceticus
Acinetobacter baumannii
Bacillus stearothermophilus
Bacillus cereus
Campylobacter jejuni
Clostridium difficile
Clostridium perfringens
Enterobacter sakazakii
Enterococcus hirae
Enterococcus faecalis Vancomycin Resistant (VRE)
Escherichia coli
Escherichia coli ESBL (Extended Spectrum beta-Lactamases)
Escherichia coli - O157 Strain
Klebsiella pneumonia
Legionella pneumophila (Sero Group 1)
Listeria monocytogenes
Methicillin resistant Staphylococcus aureus (MRSA)
Pseudomonas aeruginosa
Salmonella typhimurium
Serratia marsescens
Shigella sonnei
Stenotrophomonas maltophilia
Staphylococcus aureus
Vibrio parahaemolyticus
Yersinia enterocolitica

Mycobacterium terrae (Note – has been used for testing against TB)
Mycobacterium tuberculosis
Mycobacterium avium

Viruses: -
Avian flu (Bird Flu – Strain H5N1)
Hepatitis B and C
HIV-1 virus
Influenza virus (Strain H3N2)
Murine norovirus
Parainfluenza 3 virus,
Polio virus
Vaccinia virus,
Feline Calicivirus (Human norovirus surrogate)
Feline Coronavirus (human surrogate for SARS)
Adenovirus

Spores:-
Bacillus cereus
Bacillus subtilis
Clostridium difficile
Clostridium perfringens

Fungi and Yeasts: -

Aspergillus niger
Aspergillus fumigatus
Candida albicans
Microsporum canis
Microsporum gypseum
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Trichophyton equinum
Trichophyton mentographytes

Directions for Use

Virusolve+ concentrate product requires dilution prior to use.
Application:

Medical Devices
For Manual Disinfection of instruments and equipment:
Stage 1:
Put on PPE and wash medical device carefully in an Enzymatic cleaner and rinse
Note: The enzymatic cleaner recommended by Amity is as follows:
• Dismantle (and subsequently reassemble) the device, if necessary
• For automated processes use either Viruzyme, Viruzyme N or for the most arduous cleaning use
Duo system
• For manual cleaning use Viruzyme III
Make Virusolve+ solution at 1:20 (5%) or 50ml per litre
Stage 2:
Instruments and devices that are non-autoclavable, particularly those that are heat-sensitive or delicate in
nature (flexible and rigid endoscopes, etc.), require disinfection with specially designed chemical
alternatives like Virusolve+ Concentrate instrument disinfectant
Virusolve+ concentrate (High Level Instrument Disinfectant) is recommended for use, as follows: -
• Make sure that instrument has been thoroughly cleaned (see STAGE ONE above)
• Soak for 5 - 10 minutes making sure that all internal channels are flushed through. This ensures
bactericidal, fungicidal, virucidal, mycobactericidal and sporicidal performance is attained.
Note: Ensure that all spaces and recesses are completely filled with Virusolve+ fluid and no air
pockets exist
• Rinse in sterile water and dry with sterile material
• The medical device is now ready for use

A policy by the practice / department too carefully monitor the above will help to reduce any potential
problems. Amity would recommend to conduct the MEC test at least once per day.

Changing from an Aldehyde based disinfectant (Glutaraldehyde and OPA) to Virusolve+

The aldehyde will be absorbed into the walls of all plastics including flexible endoscopes and if no pre-
treatment is carried out there will be a chemical reaction which can cause discolouration.
To prevent this Amity would recommend to soak all plastic instruments, syringing tubes, connection tubes,
flexible endoscopes etc in a solution of Viruzyme III diluted to 1% (10ml/litre) for a minimum time of 3-4
hours but this could be extended to an overnight soak. Then rinse thoroughly.
This should eliminate 99% of the possible reaction occurring.

Non-immersible Medical Devices and Equipment

• Dilute Virusolve+ at 1:20 (50ml/litre, 5%)
• Apply the Virusolve+ solution onto a low lint cloth and wipe the relevant medical device or
equipment ensuring the full surface of the device remains wet for at least 1 minute (ILD) or 5
minutes (HLD).
• Rinse the surface of the medical device with a damp cloth of water.

For non-critical medical devices:

• Inspect device / instrument.
• Wipe thoroughly with Virusolve+ Wipes (see separate TDS) and repeat using fresh wipe(s).
• Allow to air dry
• Place in suitable holder until required for use

For maximum effectiveness, the Virusolve+ solution should be replaced every 14 days or when the
measured strength falls below the recommended 5% level or if any signs of gross soiling of the solution
is present.

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General Surface Cleaning and Healthcare Environment:

For Intermediate Level Disinfection: Dilute Virusolve+ to 0.5% with water (5ml per litre) at 20⁰C with
a 15 minutes contact time.
For High Level Disinfection: Dilute Virusolve+ to 5% with water (50ml per litre) at 20⁰C

Dispense / Spray (DO NOT MIST) Virusolve+ diluted solution directly onto the surface to be treated and
wipe gently over the whole area with a clean low lint cloth.
Allow a minimum contact time of 1 minute before wiping clean or brushing to remove grease, blood and
organic debris. Removal of stubborn deposits may be assisted by the use of a stiff bristle brush.
Rinse treated surface with clean water if required.

Food Sector
Food Preparation Surfaces
For Intermediate Level Disinfection: Dilute Virusolve+ to 0.5% with water (5ml per litre) at 20⁰C with
a 15 minutes contact time.
For High Level Disinfection: Dilute Virusolve+ to 5% with water (50ml per litre) at 20⁰C

Dispense / Spray (DO NOT MIST) Virusolve+ diluted solution directly onto the surface to be treated and
wipe gently over the whole area with a clean low lint cloth.
Allow a minimum contact time of 1 minute before wiping clean or brushing to remove grease, blood and
organic debris. Removal of stubborn deposits may be assisted by the use of a stiff bristle brush.
Rinse treated surface with clean water if required.
Note: Food preparation surfaces should be allowed to dry before use.

COP (Clean Out of Place)

Instruments and devices that require disinfection with specially designed chemical alternatives like
Virusolve+
Virusolve+ is recommended for use, as follows:
For Intermediate Level Disinfection: Dilute Virusolve+ to 0.5% with water (5ml per litre) at 20⁰C with
a 15 minutes contact time.
For High Level Disinfection: Dilute Virusolve+ to 5% with water (50ml per litre) at 20⁰C
• Make sure that instrument has been thoroughly cleaned
• Soak for 5 - 10 minutes in the diluted Virusolve+ solution, making sure that all internal channels are
flushed through. This ensures bactericidal, fungicidal, virucidal, mycobactericidal and sporicidal
performance is achieved
Note: Ensure that all spaces and recesses are completely filled with Virusolve+ fluid and no air
pockets exist
• Rinse in sterile, Deionised (DI) or Reverse Osmosis (RO) water and dry

CIP (Clean In Place)

For Intermediate Level Disinfection: Dilute Virusolve+ to 0.5% with water (5ml per litre) at 20⁰C with
a 15 minutes contact time.
• Flush for 30 minutes making sure that all internal channels are flushed through.
• Ensure that all spaces and recesses are completely filled with Virusolve+ fluid and no air pockets
exist
• Rinse is optional
• Allow to dry

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CONTACT DETAILS:

For UK and Rest of the World: For North America:

Amity International, Amity International,

Libra House, West Street, PO Box 5254,
Worsbrough Dale, 1704 Denver Road,
BARNSLEY ANDERSON,
S YORKS, S70 5PG, SOUTH CAROLINA,
ENGLAND SC29623, USA.

Tel: +44 (0) 1226 770787 Tel: 864 622 2233

Fax: +44 (0) 1226 291936 Fax: 864 622 2234

E-mail: [email protected]
Web site: www.amityinternational.com

For any further information, please contact your distributor or Amity.

In the event of any technical queries, please contact:

Mr. Ram Singh at the UK/ROW address, above, or by e-mail to:

[email protected]

Packaging Details:
Virusolve+ is available in the following packaging.
Users will need to specify requirements on their order.

125 ml 250 ml 2.5 L 5L 25 L 210 L 1000 L

bottle Bottle Container Container Container Drum IBC
Container
V+ Concentrate ✓ (1) ✓ (1) ✓ ✓ ✓ ✓ (2) ✓ (2)
V+ Conc. Lavender ✓ ✓
V+ Conc. Lemon ✓ ✓
V+ Conc. Orchid ✓ ✓
V+ Conc. Pine ✓ ✓

(1) Minimum order quantity (MOQ) applies

(2) Available on special request only

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Approval and Test Data for Virusolve+

1. Approvals.
1.1 Virusolve+ has been satisfactorily tested by leading laboratories for viral, bacterial and fungi testing.
- Micropathology Ltd, Coventry;
- H.I.R.L (Hospital Infection Research Laboratory) City Hospital Birmingham
- Bodycote Materials Testing, Law Laboratories, Birmingham.
- Texcell Laboratory (Part of Institute Pasteur®), Paris, France
- Health Protection Agency, UK.
- Retroscreen Virology Ltd (Queen Mary Hospital, University of London)

1.2 Virusolve+ has been satisfactorily tested as a disinfectant and approval granted by the UK Department
for Environment, Food and Rural Affairs (DEFRA) for the following:
- General Orders, as defined in the Diseases of Animals (Approved Disinfectant) Order 1978 at a
dilution of 1 part disinfectant to 19 parts of water.
- The Disease of Poultry Order and The Avian Influenza and Influenza of Avian Origin in
Mammals Order at a dilution rate of 1 part disinfectant to 9 parts of water.

1.3 Virusolve+ has been satisfactorily tested as an Intermediate Level disinfectant against Tuberculosis at
a dilution of 0.25% following a contact time of 15 minutes.

2. Test compliance
2.1 Testing carried out according to;
- BS6471,
- BS6424,
- BS6905,
- EN1275
- EN1276
- EN13704
- EN 13727
- EN14347
- EN 14348
- EN13697
- EN13704
- EN14476
- EN 14561
- EN 14562
- EN 14563
- EN16615 and
- AFNOR (EC) procedures.
2.2 Virusolve+ has been tested for bactericidal efficacy according to BS EN 1276 (European
Suspension Test) and demonstrates a > log 5 reduction in counts at 20 C for all three time intervals
selected.
2.3 Basic fungicidal and yeastical activity tested in accordance with BS EN 1275 (European Suspension
Test) and demonstrates a > log 5 reduction in counts at 20 C after 1, 2 and 5 minute contact times.
2.4 Sporicidal Efficacy tested in accordance with BS EN 14347 and achieved >5 log 10 reduction in all
test organisms for all contact times down to 1 minute.
2.5 Sporicidal Efficacy tested in accordance with BS EN 13704 and achieves a >3 log 10 reduction in all
test organisms for all contact times down to 1 minute.
2.6 Virucidal activity tested according to norm NFT 72-180 and passes requirement (> 4 log 10
reduction at 1 minute exposure).
2.7 Bactericidal Efficacy for disinfection of medical instruments tested in accordance with BS EN 13727
and achieved >5 log 10 reduction in all test organisms.
2.8 Bactericidal and Fungicidal Efficacy in food, industrial and institutional areas tested in accordance
with BS EN 13697 and achieved >5 log 10 reduction within a 5 minute contact time.
2.9 Complies with BS ISO 4120:2004, food taint test.
2.10 Feline calicivirus (Human norovirus surrogate), polio virus and adenovirus tests carried out in
accordance with test standards EN 14476.
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2.11 Bactericidal efficacy against Mycobacterium tuberculosis established using BS EN 14348.
2.12 Bactericidal efficacy against Mycobacterium tuberculosis following a contact time of 15 minutes and
at a dilution concentration of 0.25% established.

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