Advanced Cell Division Worksheets - Solutions
Worksheet 1: Chromosomes and Karyotypes
1. The structure of a chromosome includes two chromatids connected by a centromere. Each
chromatid contains tightly coiled DNA. Chromosomes function in genetic inheritance by carrying
genes that encode traits from parents to offspring.
2. Autosomes are chromosomes that do not determine sex and are the same in both sexes (e.g.,
chromosomes 1-22 in humans). Sex chromosomes determine an organism's sex (e.g., X and Y
chromosomes in humans).
3. Without the karyotype image, specific abnormalities cannot be identified. However, abnormalities
such as trisomy (e.g., Down syndrome - trisomy 21) can often be detected in karyotypes.
4. Karyotyping is significant in diagnosing genetic disorders and determining chromosomal
abnormalities. Examples include:
- Diagnosing Down syndrome (trisomy 21)
- Identifying Turner syndrome (monosomy X).
5. Refer to a labeled diagram showing a chromosome with a centromere and chromatids.
Worksheet 2: The Cell Cycle and DNA Replication
1. Interphase has three phases:
- G1: Cell growth and preparation for DNA replication.
- S: DNA replication occurs, doubling the genetic material.
- G2: Preparation for mitosis, including protein synthesis.
2. DNA replication ensures that each daughter cell receives an identical set of genetic instructions,
maintaining genetic continuity. For example, during mitosis, replicated DNA is evenly divided.
3. Cell cycle checkpoints (G1, G2, and M) monitor DNA integrity, cell size, and proper spindle
formation. They prevent errors, reducing the risk of mutations or incomplete division.
4. If a cell cannot progress from G1 to S phase, potential reasons could include:
- DNA damage detected at the G1 checkpoint.
- Insufficient growth signals or nutrients.
- Malfunction in cyclin or CDK proteins.
5. Refer to a simple flowchart showing the stages of the cell cycle: G1 -> S -> G2 -> M ->
Cytokinesis.
Worksheet 3: Types of Cell Division and Related Concepts
1. Mitosis vs. Meiosis:
- Purpose: Mitosis for growth and repair; meiosis for gamete production.
- Stages: Mitosis has one division; meiosis has two.
- Outcomes: Mitosis produces 2 identical cells; meiosis produces 4 genetically diverse cells.
2. Abnormal cell division can lead to cancer. Strategies to control it include:
- Chemotherapy to target dividing cells.
- Radiation therapy to destroy cancerous cells.
3. Observing cytokinesis:
- In animal cells: A cleavage furrow forms.
- In plant cells: A cell plate develops due to the rigid cell wall.
4. Number of daughter cells:
- Mitosis: Produces 2 daughter cells.
- Meiosis: Produces 4 daughter cells.
5. Importance of meiosis in genetic diversity:
Meiosis ensures variation through processes like crossing over and independent assortment.
Examples include:
- Diverse traits in offspring.
- Adaptation and evolution in populations.