Cutaneous malignancies
1.True/false regarding basal cell carcinoma?
a. Face is the commonest body site to get involved.
b. Commonly metastasizes to distant body parts.
c. Chronic arsenic exposure is a risk factor
d. There is an inherent tendency to recur
e. Excision is considered treatment of choice for discrete nodular lesions
2.Referral for Mohs’ microscopic surgery is advisable for
a.Cicatricial basal cell carcinoma
b.Large basal cell carcinoma of more than 1cm diameter
c.Discrete 5mm nodular basal cell carcinoma over the forearm
d.Nodular basal cell carcinoma over the tip of the nose
e.Superficial basal cell carcinoma in the upper back
3.True/false regarding basal cell carcinoma?
a. Superficial basal cell carcinoma can mimic nummular eczema
b. Pigmented basal cell carcinoma is only seen in individuals with pigmented skin.
c. Curettage and cautery for triple cycles is unlikely to be effective for superficial lesions.
d. Imiquimod is one of the topical treatment options
e. Gorlin’s syndrome is inherited X linked dominant manner.
4. True/false regarding squamous cell carcinoma
a. Nicotinamide is used as chemoprophylaxis in susceptible individuals
b.Common in upper lip than in lower lip
c.Moh’s microscopic surgery is recommended for high-risk tumours
d. Radiotherapy is first line treatment in middle age healthy individuals
e.Sentinal lymph node biopsies are an important part of the work up
5.Recognised risk factors for the development of squamous cell carcinoma
a.Defective DNA repair mechanisms
b.Immunosuppression
c.Ultraviolet radiation
d.Gorlin’s syndrome
e.Chronic inflammation on the skin and mucosa
6. True /false regarding metastasize potential of squamous cell carcinoma
a. Arise in sun -exposed areas of the body
b. Associated Immunosuppression
c. Diameter of less than 2cm
d. Depth of greater than 4mm
e. Arise from previous thermal injury scar
7.True/ false regarding Bowen’s disease
a. Characterised by amoeboid borders
b.65% of Bowen’s disease progress to invasive squamous cell carcinoma
c. Need to consider if an isolated psoriasis plaque does not respond to topical steroids .
d. Multiple lesions are seen in chronic arsenic exposure
e. Treated with photodynamic therapy
8.Chronic arsenic poisoning is associated with
a. Malignant melanoma
b. Rain drop pigmentation
c. Basal cell carcinoma
d. Palmoplantar focal keratoderma
e. Squamous cell carcinoma
9. Dermoscopic features suggestive of malignant melanoma include:
a. Presence of 2 or more colours within the lesion
b. Blue-whitish veil
c. Arborising blood vessels
d. Regression structures
e. Abrupt interruption of pigment network in the periphery
10. True/ false regarding the epidemiology of melanoma
a.The worldwide incidence of melanoma is increasing
b.Sunbed use is a significant risk factor
c.Sun protective measures early in life may be protective
d.Acral lentiginous melanoma is the most common type of melanoma in Caucasians.
e.Pre excisitng naevus seen in 90% of malignant melanomas.
11.True/ false regarding the types of melanoma
a.Nodular melanoma is the type commonly seen in the Chinese and Japanese skin
b.Pyogenic granuloma is considered one of the differential diagnoses
c.Sentinal lymph node biopsies are not recommended
d.Immunotherapy is considered in metastatic disease
e.Talon noir occurs in palmar skin
12. Cutaneous T cell lymphoma can be treated with the following methods
a.Nitrogen mustard
b.PUVA therapy
c.Topical corticosteroids
d.Oral vitamin A derivatives
e.Calcipitriol topical applications