‫بسم ا) الرحمن الرحيم‬

-:The following drug is classified as Immunosuppressive Agent .1

a. Theophylline
&
b. Cyclosporine
c. Prazosin
&
d. Mycophenolate Mofetil
e. b+d

:Read the following prescription carefully, then answer questions (2-5)

Lerofloxacine Tavanic 500mg Tab
Sanofi
Take 1 Tab BID
Levox-Jerusalem days 14
Levact-Pharmace
a

Tivaxin-Beit Jala
Livotreat :The drug Tavanic contains the following active ingredient .2
Leroflox-Sama a. Ceftriaxone sod
b. Ofloxacin
c. Levofloxacin
d. Clarithromycin
e. Gentamycin

-:Tavanic is classified as .3
a. Penicillin Antibiotic
b. Macrolide Antibiotic
c. Fluoroquinolone Antibiotic
d. Aminoglycoside Antibiotic
e. Cephalosporin Antibiotic

-:Tavanic is manufactured by .4
a. MSD
b. Sanofi Aventis
c. Novartis
d. Bayer
e. Eli Lilly

A locally manufactured drug that contains the same active ingredient as .5

_:Tavanic includes the following
a. Klarimax Beit Jak
>
-

Clarithromycin
b. Genticin Jerusalem
>
-

Gentamicin
Birzeit
cefurixeme
c. Zinex
&

d. Levox Jerusalem
>
-

Birzeite e. Ultracin
ofloxacin
 -:Common etiologic agents of community acquired pneumonia include .6 -

I. Esherichia coli
II. Haemophilus Influenza-

III. Mycoplasma pneumonia L

a. I only
b. III only
c. I and II only
d. II and III only
e. I,II and III
-:Pernicious anemia is .7 -

a. due to dietary deficiency of vitamin B12

.b. Prevented by oral administration of a vitamin B6 supplement
c. treated by parenteral administration of folic acid
d. treated by parenteral administration of vitamin B12
.e. Caused by dietary iron deficiency

?Which of the following statements is FALSE regarding tablet formulation .8 &

a. Diluents are fillers to add bulk to the tablet

-

.b. Lubricants help the patient to swallow the tablet more easily
c. Binding agents may be added dry or in solution
d. Disintegrants draw water into the tablet causing it to burst -
e. Glidents promote the flow of materials during compression -

:Reasons for using coatings on tablets include all of the following, EXCEPT .9 -

a. To mask the taste of the drug

b. To mask the odor of the drug -
c. To improve the appearance of the tablet
d. To increase the drug's release rate
e. To protect the drug from stomach acid X

-:Read the following prescription carefully, then answer questions (10-13)

:Rx
I.O.P eye drops
i gtt o.d t.i.d

-:I.O.P eye drops contains the following active ingredient .10

a. Dorzolamide
-
b. Sodium Cromoglycate
c. Timolol Maleate
d. Atropine sulphate -
e. Prednisolone Phosphate X

The following statement is true regarding the active ingredient in I.O.P eye .11
: -:drops
 I. Has a sulfonylurea structure
.II. Has a carbonic anhydrase inhibitor activity
.III. Is useful in the treatment of glaucoma

a. I only
b. III only
c. I and II only
d. II and III only
e. I, II and III

-:According to the prescription the drug should be taken as follows .12

a. One drop in the right eye four times daily
b. One drop in each eye four times daily
c. One drop in the left eye three times daily
d. One drop in the right eye three times daily
e. One drop in each eye three times daily

-: I.O.P eye drops is manufactured by .13 s

a. Birzeit Pharmaceutical Company

b. Pharmacare PLC
c. Jerusalem Pharmaceutical company
d. Beit Jala Pharmaceuticals company
e. Megapharm
Good
A solution has a ratio strength of 1:9000 (w/v). What is the percent weight- .14
.volume {(w/v)} of the solution
a. 0.01% d. 9%
b. 1.1% e. None of the above
c. 0.09%

A medication is available in a 200mg/5ml vial. An Rx calls for 300mg bid x .15

?10d.How many ml are needed for a single dose
a. 7.5 ml d. 150 ml

Zoom
- b. 15 ml e. 300 ml
c. 75 ml

300
mg
?What quantity should be dispensed for the following prescription .16
Rx: Prednisolone 5 mg Tab

200 2x4X2
Sig: 2 tabs qid x 2 days
tabs tid x 2 days 2x3x2 2 12

16 tabs bid x 2 days 2x2X2 2 8

tab tid x 2 days 2x3X) 1 6

 2x2X( 4

tab bid x 2 days. Then stop 1

-: Qty qs
a. 23 tablets d. 50 tablets
b. 25 tablets e. 60 tablets
c. 46 tablets

warfarin
: Which of the following drug decreases the efficacy of the drug Coumadin .17
a. Clofibrate d. Heparin
b. Metronidazole e. None of the above
c. Vitamin K antidote
-

The following laboratory test should be used to monitor therapeutic .18

-:progress of patients receiving Coumadin
a. Prothrombin time d. Creatinine Kinase
b. Bilirubin e. Allergy testing
c. Amylase

When considering the appropriateness of Glucophage monotherapy for a .19 G

patient with type II diabetes mellitus, relevant patient factors to consider

-

:include
I. Obesity ?
II. Renal dysfunction. C
III. Thyroid function.
a. I only d. II and III
only
b. III only. e. I, II and
III
.c. I and II only
se

-:All of the following are classified as Anti-hypertensive drugs except .20

a. Doxazosin - d. Amlodipine -

b. Valsartan - e. None of the above

c. Doxorubicin
-
<

:State which of the following Pharmaceutical abbreviation is not correct .21

a. p.r.n=as needed -
b. o.u = both eyes -
c. q.o.d = every other day-outdated
d. a.c = after meals -
 e. noct=at night -

:Absorption of drugs from gastrointestinal tract occurs more .22 *

a. In ionized state
b. With larger molecular size
c. In case of tertiary amines
d. With greater water solubility
e. With longer disintegration time L

:By knowing the half-life of a drug we can find out .23

a. The dose of the drug
b. Bio-availability of the drug L

c. Time to reach the steady state -

d. Rate of absorption
e. The pattern of their distribution in body

Pralidoxime is administered to patients suffering from poisoning .24 &

:With Organophosphorous compounds to

a. Reduce the cholinergic effects
b. Reactivate cholinesterase enzyme
c. Counter the central effects of acetylcholine
d. Prevent the respiratory embarrassment
e. Stimulate production of fresh cholinesterase

· 25. Which of the following endocrine abnormality may be produced by

D-2 receptor blockade caused by phenothiazines?
a. Hypothyroidism d. Diabetes mellitus
b. Hyperprolactinaemia e. Diabetes insipidus
c. Iatrogenic Cushing's Syndrome
26. Aspirin is not used in young children for antipyretic effect, because it may be
associated with:
a. Salicylism
b. Hypoprothrombinemia
c. Renal impairment
d. Metabolic acidosis
e. Reye's syndrome
-

* 27. Which one of the following drugs exhibits its anti-hypertensive effect
primarily by reduction of peripheral resistance?
a. Diltiazem d. Amlodipine
b. Clonidine e. Atenolol
c. Verapamil
SAN

⑳
A calcium channel blocker preferably used in subarachnoid haemorrhage .28
:is
 a. Verapamil d. Amlodipine
b. Nifedipine e. Nimodipine
c. Diltiazem

&
29. A diuretic that produces its action mainly by acting on the proximal part of
distal convoluted tubules is: DCT

a. Ethacrynic acid Loop of henle d. Spironolactone collecting

ducts
b. Triamterene e. Mannitol
c. Hydroxychlorothiazide

:A drug that inhibits ADP-induced platelet aggregation is .30

a. Abciximab d. Clopidogrel
b. Aspirin e. Tirofiban
c. Eptifibatide

⑧
31. While traveling by car to a hill-station, a child suffered from nausea and
vomiting. In order to prevent these symptoms to occur during return journey
you would prescribe:
a. Atropine X d. Diphenoxylate
b. Promethazine e. Chlorpromazine
c. Ondensatron

O 32. Loperamide and Diphenoxylate: Immunosuppresants

-antiinflammat
a. Are very effective in controlling the diarrhea of sever ulcerative colitis.
-

b. Are preferred for control of diarrheas caused by infections &

c. Are primarily used in treatment of diarrheas in infants 2

d. Should be preferred over ORS therapy in childhood diarrheas &

e. May produce substantial improvement in diarrhea of irritable bowel syndrome&
-

33. A patient presenting with acute episode of bronchial asthma should be

preferably treated with:
a. Oral administration of LTD-4 receptor blockers X
b. Administration of Mast Cell Stabilizing drug by aerosol &
c. Administration of long acting Beta-2 receptor agonists by inhalation
d. Administration of short acting Beta-2 receptor agonists by inhalation -

e. Oral administration of slow-release tablets of theophylline X

Which of the following drugs may be used in regimens for eradication of .34
?H.pylori
 a. Clarithromycin d. Ciprofloxacin
b. Tobramycin e. Albendazole
c. Ticarcillin

:Cellcept is calssified pharmacologically as .35

a. Antihistamine d. Anti-
inflammatory
b. Immunosuppressant e. Antitussive
c. Antidepressant

Sulphamethoxazole is combined with trimethoprim in cotrimoxazole because .36

:the two drugs
a. Have matching volumes of distribution
b. Have similar plasma protein binding
c. Have matching half lives
d. Inhibit different steps in a metabolic pathway in the organisms &

e. Are excreted through the same route

needs oxygen to get absorbed
&
· :The aminoglycosides are not effective against anaerobic bacteria because .37
a. These organisms do not have binding sites for aminoglycosides
b. These drugs fail to enter into anaerobes
c. These drugs are actively effluxed from anaerobes
d. These drugs are inactivated under anaerobic conditions
e. The anaerobes produce inactivating enzymes against aminoglycosides

:The tetracyclines are not prescribed to the growing children because they .38
Penicillin/clinda
a. May cause pseudomembranous enterocolitis cephalo
b. May cause photosensitivity Not CI for that
c. May cause sever vertigo aminoglycosides
cisplatin
d. May impair bony growth &

e. May cause Fanconi-like syndrome aminoglycosides

:Among the alkaloids of Vinca rosea .39

a. Vinblastine cause more neurotoxicity than vincristine
Vingrisihe b. Vincristine causes more bone marrow depression than vinblastine
CNS
c. Vincristine is more useful in childhood leukemias
d. Vinblastine has mechanism of action different than vincristine
-inblastine e. The clinical uses of two alkaloids are practically the same
Jone marrow
Which of the following drugs used in chemotherapy of breast cancer acts by .40 &

?inhibiting the Estrogen receptor

a. Diethylstilbestrol d. Paciltaxel
b. Tamoxifen e. Cyclophosphamide
 c. Anastrozole

41. If the dose of a drug is 50 mcg, how many doses are contained in 0.020g
a. 40. d. 100
b. 400 I soga e. 10
c. 200

002g X
Sym
=

42. One tablespoonful contains:

.

b. 10ml
a. 5ml
X00e. Non
To
S
sig
0
d. 20ml
.

of the above
05
my

c. 15ml

Which of the following may reduce the severity and duration of influenza if .43
?administered early in the course of the infection
a. Zanamivir d. a and b
b. Oseltamivir e. a and c
c. Palivizumab
monoclonal anti
body

Which of the following side effects will the patient most likely experience if .44
? using trihexyphenidyl anticholinergic
a. Diaphoresis d. Miosis
b. Diarrhea e. Urinary incontinence
c. Dry mouth

All of the following statements about intramuscular drug administration are .45
: true EXCEPT
a. entry of the drug into the circulation is affected by the drug's degree of
.lipophilicity
.b. peak effect is generally less than with intravenous administration
. c. bioavailability equals 100%
d. maximium injection volume is 2-5 ml
e. drug effects generally last longer than with intravenous administration

The most useful glucose test employed in monitoring diabetes mellitus (DM) .46
:therapy is
a. urine monitoring d. cardiovascular monitoring
b. blood monitoring e. vascular monitoring
c. renal function
 Placental transfer of a drug is affected by all of the following characteristics .47
: EXCEPT
a. molecular weight d. Lipid solubility of the drug
b. fetal sex e. plasma protein binding
c. gestational age

·
The advantage of recommending dextromethorphan instead of codeine .48
includes
a. more analgesia for muscle aches and pain
b. fifty percent as much respiratory depression M

c. fifty percent as much addiction

d. peripheral action instead of central action
.e. none of the above

: Drugs useful in treatment of infertility include all of the following EXCEPT .49
.a. bromocriptine↓ >
- prolactin
. b. clomiphene Level

.c. gonadotropin-releasing hormone

d. human chorionic gonadotropin
.e. prolactin

Hormones that are synthesized in the hypothalamus include all of the .50 ⑳

:following EXCEPT
.a. corticotrophin-releasing hormone
-
b. luteinizing hormone by anterior
c. oxytocin
d. thyrotropin-releasing hormone
e. vasopressin

51. which of the following statements about Regular Insulin is not correct:
a. It is a clear product
b. It may be administered either sc or iv -
-

c. It is a short-acting insulin
-
-

d. It is a rapid acting insulin

e. It has long duration of action
-
&

: Which of the following matches is not correct .52

- a. Mesulid Nimesulide
-
b. Simovil Simvastatin

a c. Tritace Captopril
-d. Rafassal 5-aminosalicylic acid
 e. Redoxon Vitamin C
-

The ingredient added to tablets in pharmaceutical industry to help in .53

:disintegration is called
a. Disintegrant - d. Dissolution-enhancing agent
b. Lubricant L e. Binder
c. Surfactant 2

:Bromhexin is used clinically as .54

a. Laxative d. Mucolytic
b. Cough suppressant e. Diagnostic agent
c. Haemostatic

Streptokinase is used in treatment of .55

a. Celiac disease d. lung cancer
b. Pulmonary emboli e. none of the above
c. tuberculosis

56. Which of the following drugs is used in the treatment of a diabetic

pregnant woman:
a. Insulin d.
Metformin
b. Chlorpropamide e. none of the above
c. Glibenclamide

Amlodipine is classified as .57

a. Antitussive d. ACE inhibitor
b. Antispasmodic e. none of the above
c. calcium channel blocker

:The drug that decreases Uric acid production in the body is .58
a. Allopurinol d.
Propylthiouracil
b. Phenylbutazone e. Probencid
c. Famotidine
 59. Which of the following pharmacological classes should not be used
during pregnancy:
a. Narcotics d.
Diazepam
b. Alcohol e. all of the above
c. Barbiturates

:Which of the following vitamins is lipid soluble .60

a. Vitamin A d.
Pyridoxine B6
b. Thiamine e. Ascorbic acid 1 . (

c. Niacin
Bs
Patient should be cautioned not to consume alcoholic beverages when given a .61
: prescription for any of the following EXCEPT
a. cefixime. d. glipizide
b. chloral hydrate e. metronidazole
.c. chloropropamide

When a patient is prescribed glyceryl nitrate (nitroglycerine) tablets they .62

:must
a. store them in a tightly closed glass bottle
b. Keep a couple of tablets in their pocket or purse for emergency use pockets
>
-

c. Swallow them whole with a glass of water S L >

-
.

d. Take them regularly e.g. 8 hourly

e. all of the above.

A patient suffering from depressive disorder is being treated with imipramine .63
if he uses diphenhydramine for allergic rhinitis a drug interaction is likely to
:occur because
a. diphenhydramine inhibits imipramine metabolism
b. both drugs block reuptake of norepinephrine release from sympathetic nerve
.endings
.c. imipramine inhibits the metabolism of diphenhydramine
.d. both drugs block muscarinic receptors
e. the drugs compete with each other for renal elimination

Agents that have been shown to protect the upper gastrointestinal tract from .64
:ulcer formation include all of the following EXCEPT
a. antacids d. misoprostol
.b. cimetidine e. sucralfate
 c. ibuprofen

:The drug Prozac contains .65

a. paroxetine d. trimiprane
.b. trazodone e. fluoxetine
c. sertraline

66. The drug Cialis contains:

d.vardenafil a. testosterone
b. alprostadil e.sildenafil
c. tadalafil

A locally manufactured drug that contains the same active ingredient as .67
:Cialis

a. sinagra
b. fortex
c. v-care
d. all of the above
.e. none of the above
:The manufacturer of Cialis is .68
a. Novartis
b. GSK
c. Lilly
d. Pfizer
.e. Roche

units of Heparin are added to 1 Liter of 0.9% Saline. Dose prescribed is 10,000 .69
.400 units per hour. Calculate the rate of infusion in ml/hr
a. 4 ml
b. 0.4 ml
c. 40ml
-

d. 400ml
e. 100ml

Digoxin injection is available in concentration of 0.1 mg/ ml .How many .70

?milliliters of the injection will provide a dose of 75 mcg
a. 7.5 ml
b. 75 ml
c. 0.75ml
-

d. 10ml
e. 0.1 ml

:In dispensing the Latin abbreviation for "at bedtime" is .71

 .a. b.i.d
.b. hrs
.c. h
.d. h.s
.e. prn

72. Atropine sulphate is used to treat the poisoned patients with:

a. Cyanide
b. Iodine 1-131
c. Organophosphate
d. Iron
e. Methanol

73. Which of the following conjugation reactions occurs inside the

-
microsomes of hepatocytes ?
a. Sulfate conjugation
b. Acetylation
c. Glycine conjugation
d. Glucuronide conjugation
e. Glutathione conjugation

74. The drug Crestor contains the following active ingredient:

a. verapamil
b. pravastatin
c. rosuvastatin
-

d. ramipril
e. cilazapril

75. Crestor is classified as:

a. ACE inhibitor
b. statin type hypercholestrolemic agent
c. calcium antagonist hypotensive agent
d. B blocker
.e. statin type hypocholestrolemic agent

76. Symbicort Turbuhaler contains:

a. Budesonide
b. Formoterol
c. Salmeterol
d. a+b
e. a+c

77. Symbicort Turbuhaler is manufactured by:

a. Sanofi Aventis
b. GSK
c. AstraZeneca
d. Abbot
e. Novartis

Read the following prescription carefully, then answer questions (78- 80)

Rx:- Prazolex 1mg Tab

Tab T.I.D 1

-:Prazolex Tab contains the following active ingredient .78

a. Clozapine
b. Haloperidol
c. Risperidone
d. Alprazolam
e. Bromazepam

-:Prazolex is classified as .79

a. Benzodiazepine Anxiolytic
b. Atypical Antipsychotic
c. Phenothiazine Antipsychotic
d. Piperidine Antipsychotic
e. None of the above

-:Prazolex Tab is manufactured by .80

a. Birzeit Pharmaceutical Company
b. Pharmacare PLC
c. Jerusalem Pharmaceutical company
d. Beit Jala Pharmaceuticals company
e. Megapharm

-:The drug Glivec is classified as .81

a. Anti-spasmodic agent
b. Anti-arrythmic agent
c. Anti-neoplastic agent
d. Anti-diabetic agent
e. Anti-hypertensive agent
:The active pharmaceutical ingredient in Amaryl is .82
a. glibenclamide
 b. metformin
c. glimepiride
d. chlorpropamide
e. glipizide

:Myocardial oxygen demand is increased by all of the following factors EXCEPT .83
a. exercise
b. smoking
c. cold temperatures
d. isoproterenol
e. propranolol

84. The most serious adverse reaction that may occur with the use of Thionamide
antithyroid drugs is:
a. Agranulocytosis
b. Joint pains
c. Paresthesias
d. Alopecia
e. Skin rashes

Potential adverse effects associated with aspirin include all of the following .85
:EXCEPT
a. gastrointestinal ulceration
b. renal dysfunction
c. enhanced methotrexate toxicity
d. cardiac arrhythmias
e. hypersensitivity asthma

86. Which of the following will increase the half-life of theophylline?

a. carbamazepine inducers
-

b. cimetidine inhibitors
-

c. Phenobarbital inducers
-

d. smoking inducers
-

e. all of the above

87. Which of the following metals has no therapeutic use:

a. lead &
highly toxic
b. lithium
c. gold
d. platinum
.e. none of the above

88. Which of the following enhances digitalis toxicity by pharmacokinetic

mechanism:
a. captopril.
 b. hydrochlorothiazide
c. lidocaine
d. quinidine
e. salfasalazine

:Thiazides are known to reduce excretion of .89

a. diazepam
b. fluoxetine
c. imipramine
d. lithium
e. potassium

90. A hypertensive patient has been using nifedipine for sometimes without
outwards effects. If he experiences a rapidly developing enhancement of the
antihypertensive effect of the drug it is probably due to:
a. concomitant use of antacids.
b. foods containing tyramine.
c. grapefruite juice. Inhibits metabolism
d. induction of drug metabolism.
.e. over-the-counter decongestant

(100-91) ‫سئلة من‬1‫ على ا‬4 ‫أجب بنعم أو‬:

91. ‫كثر من مؤسسة صيد)نية واحدة‬3 ‫يجوز للصيدلي أن يكون مالكا‬.
(X )
32m

92. ‫ متر مربع‬40 ‫يجب أن ) تقل مساحة الصيدلية عن‬. ( - )

93. ‫ي كان‬3 ‫فرق‬K‫دوية بالجملة و ا‬3‫دوية مخصص لبيع ا‬3‫مستودع ا‬. ( X
-

)
94. ‫صول بسبب سفره إلى‬3‫ شهرا فقط حسب ا‬15 ‫دة‬K ‫صيدلية أغلقها صاحبها‬
‫الخارج و عندما رجع له الحق بإعادة فتحها و ممارسة عمله‬.
( X )
95. ‫يجوز أن يكون تاريخ انتهاء الدواء مختوما بالحبر أو مطبوعا من قبل الشركة‬
‫الصانعة‬. *

( X )
96. ‫) يجوز أن يكون للصيدلية العامة باب فرعي آخر يتصل بمنزل الصيد)ني‬
‫سئول‬K‫ا‬.

(-
)
97. ‫بر في الصيدلية من قبل أي كان‬o‫يجوز حقن ا‬. ( X )
98. ‫) يجوز أن يكون باب الصيدلية الخاصة التابعة لجمعية خيرية على الشارع العام‬.
 ‫‪( -‬‬ ‫)‬
‫يجوز للصيدلي ا‪K‬الك و ا‪K‬سئول عن الصيدلية العمل كمندوب دعاية با‪o‬ضافة إلى ‪99.‬‬
‫‪.‬عمله في الصيدلية‬ ‫) ‪(X‬‬
‫يلغى الترخيص ا‪K‬منوح من الوزارة في حال تم بيع الصيدلية دون علم و موافقة ‪100.‬‬
‫‪.‬الوزارة‬ ‫)‪( -‬‬

‫‪،،‬مع تمنياتنا لكم بالتوفيق‬

‫‪13‬‬